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Glucose To Fat Pathway

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Importance of lipid metabolism; general overview of atherosclerosis

Lipid Metabolism - An Overview | Sciencedirect Topics

Isabelle Coppens, ... Stanislas Tomavo, in Toxoplasma Gondii (Second Edition) , 2014 Fatty Acid Biosynthetic Pathways Generalities 270 Phospholipid Biosynthetic Pathways Generalities 274 Phospholipid Composition and Physiological Relevance in Toxoplasma 274 Glycerolipid Biosynthetic Pathways Generalities 277 Sterol Lipid Biosynthetic Pathways Generalities 278 Sterol Salvage and Transport in Toxoplasma 279 Sphingolipid Biosynthetic Pathways Generalities 280 Isoprenoid Biosynthetic Pathways Generalities 282 Balasubramaniyan Vairappan PhD, in Molecular Aspects of Alcohol and Nutrition , 2016 Prime Involvement of Leptin on Regulation of Lipid Metabolism Lipid metabolism is regulated by several hormones, and leptin is considered one of them. It is a balance between lipid synthesis and degradation that determines fat mass. Over 90% of total energy reserves are stored in adipocytes, such as TG, that can be hydrolyzed (lipolysis) following hormonal stimulation to release FA. FA has two possible fates: -oxidation to produce ATP, or re-esterification back into TG. Many studies have shown that leptin has a direct autocrine or paracrine mode of action on lipid metabolism.104,107,116 Leptin ap Continue reading >>

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  1. Margot LaNoue

    Maybe, but it depends on a few factors:

    What are the net carbs in the bar? (n)
    n = (grams carbs) - (grams fiber)

    How many carbs have you already consumed today? (x)
    x = total carbs before protein bar
    If (n+x) > 40 then you've probably been kicked out of keto.
    If (n+x) < 40 then you're probably still in keto.
    Your personal limit may differ from my general rule of 40g net carbs per day. Since you know your body best, go with your personal number. To test your limits, use keto sticks to test your urine for the presence of ketones. Color doesn't matter because being in ketosis is like being pregnant. You can't be a little pregnant, you either are or aren't.

  2. Steve Clarke

    It depends entirely on the types of carbs.
    Simple carbs will increase insulin secretion but 17g should be OK... just be careful.
    If the carbs were in fact fiber (Quest bars) you'll be absolutely fine. They are my go to treat when I play with Ketosis.
    Keep your carbs below 50g and get most from fiber and complex carbs.
    Also to note: Some processed sugars will cause insulin spike also.

  3. Raj Patel

    Most likely not. But it depends on how many total carbs you ate that day. Also if all those 17 grams are from sugar or not? It is a lot of carbs in one shot. If your on a ketogenic diet I would avoid protien shakes and bars.

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Pathways In The Coordination Of Cellular Glucose And Fat Metabolism

Pathways in the coordination of cellular glucose and fat metabolism Last Updated on Sat, 04 Mar 2017 | Fatty Acids The metabolism of fat and carbohydrate are closely linked; optimal oxidation of fat and conservation of glucose occur in the fed state and the opposite in the fasted state. Current theory identifies two major biochemical pathways as central components of this integrated coordination of energy metabolism . These are the glucose-fatty acid cycle first described in 1963 (Randle et al., 1963) and the malonyl CoA / carnitine palmitoyl transferase (CPT)-1 pathway which was suggested by the studies of McGarry and coworkers in the late 1970s (McGarry et al., 1977). Importantly, these two pathways complement each other (Fig. 2.1). The glucose- fatty acid cycle links carbohydrate and fat metabolism and was one of the first theories to describe how fatty acids influence glucose metabolism . It centres on the proposition that increased beta-oxidation (utilisation) of fatty acids in skeletal muscle results in a reduced uptake and oxidation of glucose (Fig. 2.1), offering additional fine-tuning to the 'coarse' control of glucose and fat utilisation that is enforced at whole body le Continue reading >>

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  1. Lmalhoit

    Anyone ever fasted away a cold? I've read a few things about how it might help, maybe because of autophagy. Any science out there on this?

  2. Jason_v

    a cold has nothing to do with autophagy. that is where the body eliminates its own, damaged cells. a cold is a viral infection that the body fights off. the last thing you would probably want to do is start fasting ( a hormetic stress on the body) when its attempting to rally its resources and fight something off. fasting is great when applied correctly but its not magic.

  3. Lmalhoit

    I know this article may not be totally legit, but I guess I was thinking more along the lines of building immunity. Http://authoritynutrition.com/can-fasting-fight-the-flu-or-cold/

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Video by Ulf Smith, MD, PhD, Professor of Internal Medicine, The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Sahlgrenska Academy, Gteborg University, Gteborg, Sweden Produced by the International Chair on Cardiometabolic Risk

Conversion Of Carbohydrate To Fat In Adipose Tissue: An Energy-yielding And,therefore, Self-limiting Process.

Conversion of carbohydrate to fat in adipose tissue: an energy-yielding and,therefore, self-limiting process. A theoretical analysis of the energy metabolism associated with the conversion ofglucose to fat is presented. In tissues where the pentose cycle furnishes some ofthe NADPH required for fatty acid synthesis, this conversion is an ATP-yieldingprocess. In rat adipose tissue the maximal rate of glucose conversion to fat can be quantatively predicted on the basis of the tissue's ability to use the ATPwhich is generated in excess during this conversion. The energy-generating natureof this process provides the means for a type of regulation which depends onmetabolic state and which, during fasting, contributes to the sparing ofcarbohydrate. Impairment of lipogenesis in the fasting state is attributed to adecrease in the activity of the malate cycle and to the presence of free fattyacids. However, rather than by inhibiting specific enzymes, it is by virtue oftheir quality as substrates for energy production that free fatty acids and theirCoA derivatives appear to inhibit de novo lipogenesis. The regulatory phenomenadiscussed here may explain the failure of the attempts made to ide Continue reading >>

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  1. tagyourit

    LC WOE noob on day #5 of Induction here! I bought the Ketostix 3 days ago and have been testing daily as "Trace".
    I have few questions re: Ketosis -
    Should I be testing at the same time of day?
    Should I test only 1 time/day or more?
    What level should I be aiming for/sustaining?
    I know everyone's body is different therefore the results will differ from my own, but I'd like to know how long it took you to go into Ketosis?
    Thanks in advance for the help & info!

  2. dansamy

    I can reliably be in ketosis by the third morning. I test morning because when I'm eating a high carb diet, I'm never in ketosis, even with first morning urine. You could test before bed to see if your day's eating has pushed you out.

  3. tagyourit

    Thanks dansamy!

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