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Glucose To Fat Pathway

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The Science Behind Fat Metabolism

Per the usual disclaimer, always consult with your doctor before experimenting with your diet (seriously, go see a doctor, get data from blood tests, etc.). Please feel free to comment below if you’re aware of anything that should be updated; I’d appreciate knowing and I’ll update the content quickly. My goal here is to help a scientifically curious audience know the basic story and where to dive in for further study. If I’m successful, the pros will say “duh”, and everyone else will be better informed about how this all works. [UPDATE: based on a ton a helpful feedback and questions on the content below, I’ve written up a separate article summarizing the science behind ketogenic (low-carb) diets. Check it out. Also, the below content has been updated and is still very much applicable to fat metabolism on various kinds of diets. Thanks, everyone!] tl;dr The concentration of glucose in your blood is the critical upstream switch that places your body into a “fat-storing” or “fat-burning” state. The metabolic efficiency of either state — and the time it takes to get into one from the other — depends on a large variety of factors such as food and drink volume Continue reading >>

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Popular Questions

  1. tblake87

    Is the ketogenic diet related to kidney stones?

    I've been surfing the web to find some good KETO recipes and I came across multiple sites that stated being on a KETO diet raised your chances for kidney stones immensely. Taking the odds form 1 in several thousand to 1 in 20. I've had a kidney stone before and that is definitely something I don't want to go through again. Can anyone verify this?

  2. hjmacd1984

    Im not 100% sure, but I think youre more at risk the more protein you consume - being on keto should be okay as youre taking in around 1-1.5lbs per lbs LBM.. whereas something like the palumbo diet I think you'd be relying more on high protein and moderate fat.
    Not completely sure, maybe check with your doc... maybe its not suitable for you seeing as youve already had kidney stones, just check

  3. Eileen

    Lot of nonsense. It's based on the totally unproven idea that high protein diets will damage your kidneys. Not only are there no studies showing this, there hasn't been a single documented case of it. The only problem keto is likely to cause your kidneys is that keto is a duiretic diet, so you don't drink enough, your piss won't be dilute enough and that could cause problems.
    In any case, keto is not a high protein diet, it's moderate protein. Look at the Nutrition forum and you'll find guys packing away 200-350g of protein a day and none of them are worrying about exploding kidneys. Most people here are eating half that.

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