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Glucose Ketone Index (gki) Calculator

Tracking The Glucose Ketone Index

Tracking The Glucose Ketone Index

In this post we will examine the “glucose ketone index” as a biomarker for tracking metabolic health. We will also explore some of the primary use cases for tracking the glucose ketone index including cancer treatment, weight loss, metabolic disease management and athletic performance. Lastly, we will demonstrate how you can use Heads Up Health to track the glucose ketone index along with all of your other important health data. If you want to skip ahead, click the button below to create an account with Heads Up and start tracking the glucose-ketone index alongside all of your other health metrics. Or, read on for more information on tracking the glucose ketone index. What is the Glucose Ketone Index? The glucose ketone index is simply a way to measure the relationship between your ketone levels and your glucose levels at any moment in time. It is measured by dividing your blood glucose level (mmol/L) by your blood ketone level (mmol/L). The result is a single number we can use an indicator of one’s metabolic state. The index has its roots in brain cancer treatment, where researchers using metabolic therapy found best results when glucose and ketones maintained a very precise relationship in the patient [1]. Since there are many aspects of daily life (stress, exercise, nutrition etc.) that can upset glucose or ketone levels in the body, thereby throwing off the optimal glucose-ketone ratio, the index was developed to ensure both metrics (glucose and ketones) are maintaining the ideal ratio for optimal treatment outcomes. Example: If my fasting blood sugar first thing in the morning is 4.6 mmol/L (82 mg/dL) and my ketone reading is 0.8 mmol/L, I would record a glucose ketone index of 5.75 (4.6 / 0.8). Despite its roots in cancer treatment, the index can also be ver Continue reading >>

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic Joshua J Meidenbauer, Purna Mukherjee and Thomas N Seyfried Background: Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic fermentation of glucose (Warburg effect), w hich i s the common metabolic malady of most cancers including brain tumors. The KD targets tumor energy metabolism by lowering blood glucose and elevating blood ketones (-hydroxybutyrate). Brain tumor cells, unlike normal brain cells, cannot use ketone bodies effectively for energy when glucose becomes limiting. Although plasma levels of glucose and ketone bodies have been used separately to predict the therapeutic success of metabolic therapy, daily glucose levels can fluctuate widely in brain cancer patients. This can create difficulty in linking changes in blood glucose and ketones to efficacy of metabolic therapy. Methods: A program was developed (Glucose Ketone Index Calculator, GKIC) that tracks the ratio of blood glucose to ketones as a single value. We have termed this ratio the Glucose Ketone Index (GKI). Results: The GKIC was used to compute the GKI for data published on blood glucose and ketone levels in humans and mice with brain tumors. The results showed a clear relationship between the GKI and therapeutic efficacy using Conclusions: The GKIC is a simple tool that can help monitor the efficacy of metabolic therapy in preclinical animal models and in clinical trials for malignant brain cancer and possibly other cancers that express aerobic fermentation. Keywords: Glucose, Beta-hydroxybutyrate, Calorie restriction, Metabolic therapy, Glioblast Continue reading >>

Glucose Ketone Index For Metabolictherapy - The Trustees Of Boston College

Glucose Ketone Index For Metabolictherapy - The Trustees Of Boston College

Glucose Ketone Index for MetabolicTherapy United States Patent Application 20160078782 The ratio of blood glucose to blood ketones as a single Glucose Ketone Index value is tracked to manage metabolic treatment. This ratio identifies a metabolic state of health and has potential use for monitoring the progression of a metabolic or inflammatory disease or indication for all types of cancer, neurological disorders, and chronic inflammatory diseases. The tracking can be performed by a device or kit, such as a Glucose Ketone Index Calculator. Meidenbauer, Joshua J. (Auburndale, MA, US) THE TRUSTEES OF BOSTON COLLEGE (Chestnut Hill, MA, US) Bond Schoeneck & King, PLLC (350 Linden Oaks 3rd Floor Rochester NY 14625) 1. A method for managing the metabolic treatment of a subject comprising: administering a diet to the subject, wherein the diet reduces blood glucose levels and elevates blood ketone levels in the subject; tracking the ratio of blood glucose to blood ketone levels in the subject as a single Glucose Ketone Index value; and maintaining the tracked Glucose Ketone Index value within a target range. 2. The method of claim 1, wherein the maintaining the tracked Glucose Ketone Index value within a target range comprises altering the diet administered to the subject. 3. The method of claim 1, wherein the diet comprises at least one of a ketogenic diet, calorie restricted diet, nutritional supplementation, pharmacological therapy, low carbohydrate diets, ketone ester supplementation, and therapeutic fasting. 4. The method of claim 1, wherein the target range is a Glucose Ketone Index value from about 0.5 to about 5. 5. The method of claim 1, wherein the metabolic treatment comprises treatment for a metabolic or inflammatory disease or indication. 6. The method of claim 5, Continue reading >>

It Really Is In Your Blood: Glucose To Ketone Ratios

It Really Is In Your Blood: Glucose To Ketone Ratios

I wrote awhile back about how I felt that I might be going a little mad obsessing over my blood numbers and measuring my blood glucose and ketone levels. This is one of the greatest differences, in my opinion, between people that follow a ketogenic or low carb lifestyle for overall health reasons or weight loss, and those of us who are experimenting with using a ketogenic approach as a specific disease therapy. I’m using the term “therapeutic ketosis” now for this, as you’ll know if you’re a Constant Reader here at Greymadder. I think people in the first category, with weight loss or general health goals, can definitely be helped by measuring ketones, and that this is vital to the success of the approach. However, in my personal experience using this approach to “starve” my brain tumour, I find I can become quite the data junkie, measuring blood levels of both glucose and ketones up to four times a day, because in my mind, the optimal levels of both are perhaps what’s required to have a therapeutic effect. I base this on the book Cancer as a Metabolic Disease by Dr. Thomas Seyfried, in which he advises that there is a window of effectiveness of therapeutic ketosis for cancer that uses a glucose to ketone ratio of 1.0. This essentially means that when measured in mmol/L (“millimolar”), blood glucose and ketones should be equal, or even achieving ketone levels that are higher than the glucose levels may be preferable. There is general agreement between my favourite go-to references (Ellen Davis, Dominic D’Agostino, Miriam Kalamian, all found in my Resources section) that this glucose to ketone ratio of 1.0 is best. Miriam Kalamian, in her ebook Get Started with the Ketogenic Diet for Cancer further notes that it should not be disregarded that a thera Continue reading >>

Glucose Ketone Index Calculator | Optimising Nutrition

Glucose Ketone Index Calculator | Optimising Nutrition

A low carb helps reduce blood sugars and insulin levels. Blood glucose control and improved metabolic health will help to reduce your risk of many of the diseases of modern civilisation such as diabetes, heart disease, stroke, cancer, Parkinsons and Alzheimers. We become insulin resistant when our body fat cant store more energy. Once our adipose tissue becomes insulin resistant, excess energy is stored in theliver, pancreas, heart, brain, eyes and other organs that are more insulin sensitive. Once our body fat cant hold the excess, we see increased levels of energy in our blood in the form of glucose, ketones and triglycerides. Endogenous ketosis occurs when weeat less food than we need. Our insulin and blood sugar levels decrease and ketones rise to supply the energy we need. Exogenous ketosis occurs when we eat lots fat and/or take exogenous ketones. Blood ketones rise, but our insulin levels will also increase because we have an excess of energy coming from our diet. While a low carb or ketogenic diet helps to stabilise blood sugars, most of the good things associated with ketosis occur due to endogenous ketosis, that is, when we drive lower levels of energy in our system. If your goal isblood sugarcontrol, longevity orweight loss then endogenous ketosis with lower blood sugars and lower ketones is likely a better place to be than higher blood ketones. There has been a lot of interest and confusion recently from people following a ketogenic about ideal ketone and blood sugar levels. In an effort to try to clear this up, this article reviews blood ketone (BHB), breath ketone (acetone) and blood sugar data from a large number of people who are following a low carb or ketogenic diet to understand what normal and optimal look like. low carb diets reduce blood glucose l Continue reading >>

Therapeutic Water Fast

Therapeutic Water Fast

All keto. All the time. Kombating Ketogenic Kognitive Dissonance of the Ubiquitous 'Others' Sunday, April 13 2015 I decided to prolong my 'down day' fast of Saturday. I will be doing a therapeutic water fast for up to 20 days as tolerated. After seeing discussion in the Optimal Ketogenic Living Facebook ( ) group (thank you, Raymund Edwards), I thought it would also be a good time to start my own mitigation. So I am considering today "Day 2.5" since my last 'meal' was mid-day on my down day Saturday. Seyfried's premise: While the medical community continues to chase gene mutations in cancer... It is what is *causing* the gene mutations we are not focusing on: the mitochondria. I am looking forward to the following benefits: Cleanup of all the defective cells from the prolonged illness, Eating the plaques in all vessels, but especially the coronary arteries and brain, Improving overall inflammation, but especially that which continues to plague me in terms of headaches and carpal tunnel Dad has type 2 diabetes and coronary artery disease... And Mom has severe osteoporosis and is clearly suffering from dementia of God knows what cause. Her episodes have become more frequent in the last two months, so much so that they will be coming to live near us so we can help. Now that I am healthy enough to do this, it is time to do it, and then do it yearly. Average Ketonix was Green 5 or about 1.3 mmol for the week. I am not excessively concerned with "weight" loss during this time. Some loss of lean body mass is to be expected, but since I am already keto-adapted, this should be fairly minimal over the course of the therapy. There is no doubt that much "weight" will also be water weight which will return upon refeeding (probably up to 4 pounds). "Weight loss" is NOT the primary g Continue reading >>

Keto Katie All Things Ketones

Keto Katie All Things Ketones

The glucose ketone index is a ratiototrack your metabolic state. Dr. Thomas Seyfried suggests in his book, Cancer as a Metabolic Disease ,that you aim for a GKI between 0.7 to 2.o with a goal of 1. Today, Todd hit 1! When fighting cancer with the Ketogenic Diet, the goal is to depletethe supply of sugar/glucoseto thecancer cells and elevate the blood ketone level between 2-5 mmol depending on who you ask. Elevated ketone bodies have a very promising effect on shrinking tumors in lab & case studies. Getting your blood glucose down & ketones elevated can be a challenging task for some. What works for some may not for others. Through trial & error, Todd found out that tomatoes, almonds & too much dairy will kick him out of ketosis . There are many factors that play into the equation of raisingglucose including too much protein to any type of stress on the body. Heres how we got to 1. Precision Xtra monitor measure blood glucose in mg/dl and ketones in mmol so the glucose needs to be converted into mmol. Continue reading >>

Glucose Ketone Index (gki) Calculator

Glucose Ketone Index (gki) Calculator

Enter your blood glucose in (mg/dL) or (mmol/l) * Lower GKI values are associated with more therapeutic benefits of ketosis (cellular repair, autophagy, apoptosis, reduced inflammation, disease prevention). Dr. Seyfried does a lot of his research in the realm of cancer treatment and has noticed increasingly impressive therapeutic outcomes with the lower the glucose ketone index ratio gets. Dr. Seyfried claims that a GKI of lower than 1.0 is prime therapy for patients with cancer, and he has plenty of data to back this up. Were all for using tools to improve our health and meet personal goals for our body. If youve never heard of or used the glucose ketone index (GKI), nows the time to learn more about this useful tool. This article will fully explain what the glucose ketone index is and why it matters that we all use it. The glucose ketone index (GKI) is a single number that gives you a way to monitor the state of your metabolic health. Tracking your ketone levels lets you know how far you are into ketosis , and the GKI gives you a picture of the relationship between your ketone levels and your glucose levels. Its simply an even more efficient way to see where you stand with your health. Lets take a second to talk about what metabolic health means, as this needs to be clarified for two reasons: Many people who hear the term think of metabolism , which has been watered down a lot in recent times and is often misunderstood (such as the myth that intermittent fasting kills your metabolism, etc), and its not the same as an overall picture of metabolic health. Metabolic health has been defined in many different ways by researchers depending on whats being measured: triglycerides, blood pressure, cholesterol, etc. Perhaps most commonly, we see it used in tandem with research Continue reading >>

Gki (glucose To Ketone Index)

Gki (glucose To Ketone Index)

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community I posted this in the prediabetes forum and someone there suggested I try my posting in this forum as well. So...here it is; Michael here from Tasmania in Australia. Just briefly, I was obese and prediabetic for an excess of 15 years until I discovered intermittent and longer term fasting. I have now lost in excess of 20 kg and whilst I haven't tested my HbA1c for a while am probably no longer prediabetic. I will test my bloods again soon. When doing longer fasts (up to 21 days) I would regularly test my BSL and ketones. I learned that dividing BSL by ketones gives an index called GKI (glucose to ketone index). This is apparently an accurate way of assessing insulin levels in the blood. A GKI of 1 or less is optimal. This morning (my 7th and last day of my current modified water fast), my BSL was 3.1 and my ketones were 3.4. This gives me a GKI of less than 1. I'm happy with that, have lost just under 5 kg in 7 days (though I'm aware I will regain a couple of kilo in water), have absolutely no signs of hypoglycaemia and I feel good. My question is, does anyone else use GKI? Anyone got any research on the reliability and/or validity of using GKI to assess insulin levels in the blood. What a great forum. Very happy to have come across it. Well so much for my theory @Tassiemike ......... Perhaps you'd have more luck over at reddit or maybe the 2 keto dudes forums? I posted this in the prediabetes forum and someone there suggested I try my posting in this forum as well. So...here it is; Michael here from Tasmania in Australia. Just briefly, I was obese and prediabetic for an excess of 15 years until I discovered intermittent and longer term fasting. I have Continue reading >>

How To Easily Track Your Glucose Ketone Index (gki) On Your Ketogenic Diet

How To Easily Track Your Glucose Ketone Index (gki) On Your Ketogenic Diet

Tracking ketone levels is a large part of success on the ketogenic diet. It helps you know how far you are into ketosis and where we might need to make changes. But did you know that there’s an even better way to step it up a notch? The glucose ketone index is a simple calculation that allows you to find out how ketosis works best for you individually. Without it, you could be in full, high-level ketosis yet still not getting the full benefits. In this post, we’ll be looking at how to easily track your glucose ketone index for different aspects of health along with your ketogenic diet. Basics of the Glucose Ketone Index Here’s what you need to know about the glucose ketone index (GKI): Researchers have used the index in studies on the ketogenic diet, fasting, and more. Additionally, it has been used for tracking changes and progress regarding weight loss, athletic performance, management of metabolic diseases like type 2 diabetes, and even cancer treatment. Now that we’ve covered the basics of what the GKI does, let’s talk about how you can use tracking it to your advantage. Tracking Your Glucose Ketone Index What’s so special about the glucose ketone index is that it lets you track both glucose and ketones at the same time, taking into account how they work together. It’s a way to know your optimal state for addressing all sorts of health conditions. Tracking this number benefits you over simply measuring ketone levels. That’s because even if you’re deeply in ketosis, you could still have high blood glucose levels that throw things off and affect your health. Essentially, it gives you a more full picture of your metabolic health. The numbers you can expect to target depend on your intentions for being in ketosis. Is your goal weight loss, better overa Continue reading >>

Glucose Ketone Index Calculator For Cancer Management

Glucose Ketone Index Calculator For Cancer Management

Glucose Ketone Index Calculator For Cancer Management This is a fantastic article statingthe incredible benefits of using ketogenic diet for the metabolic management of cancer. To calculate your index you will need to have a blood glucose monitor and a blood ketone monitor to obtain your Glucose Ketone Index (GKI). Paying attention to the optimal ratio of your glucose and ketones has been scientifically proven to be a powerful tool for the metabolic management of brain tumors (and other aggressive and inoperable cancers). Mary Beauchamp is a Registered Nurse, Therapeutic Nutritionist and Mind Body Specialist. She is a world traveler, food alchemist, and student of ancient healing traditions. She has four beautiful children and two grandchildren. With her knowledge of nutritional science, medical research, plant medicines, ancient super foods and indigenous healing rituals, she formulates food products for the natural foods industry and is a private health coach, specializing in healing the metabolism. Mary works with a team of Naturopathic doctors at Auburn Naturopathic Medicine in northern California. She alsooffers private and group online coaching programs. You can learn more about her work by visiting her website, www.ketogenicdietcoach.com . Mary is passionate about re-educating people about nutrition. She invites you to experience your body as a master communication system and facilitates this sacred encounter within to unlock the bodys innate intelligence to heal and thrive! Continue reading >>

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer Meidenbauer et al.; licensee BioMed Central.2015 Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic fermentation of glucose (Warburg effect), which is the common metabolic malady of most cancers including brain tumors. The KD targets tumor energy metabolism by lowering blood glucose and elevating blood ketones (-hydroxybutyrate). Brain tumor cells, unlike normal brain cells, cannot use ketone bodies effectively for energy when glucose becomes limiting. Although plasma levels of glucose and ketone bodies have been used separately to predict the therapeutic success of metabolic therapy, daily glucose levels can fluctuate widely in brain cancer patients. This can create difficulty in linking changes in blood glucose and ketones to efficacy of metabolic therapy. A program was developed (Glucose Ketone Index Calculator, GKIC) that tracks the ratio of blood glucose to ketones as a single value. We have termed this ratio the Glucose Ketone Index (GKI). The GKIC was used to compute the GKI for data published on blood glucose and ketone levels in humans and mice with brain tumors. The results showed a clear relationship between the GKI and therapeutic efficacy using ketogenic diets and calorie restriction. The GKIC is a simple tool that can help monitor the efficacy of metabolic therapy in preclinical animal models and in clinical trials for malignant brain cancer and possibly other cancers that express aerobic fermentation. GlucoseBeta-hydroxybutyrateCalorie restrictionMetabolic therapyGlioblastomaWar Continue reading >>

Biohacking: Using The Glucose Ketone Index

Biohacking: Using The Glucose Ketone Index

Looking for a way to measure metabolic health? One technique is to look at the ratio of blood glucose to blood ketones. The idea is to reduce carbohydrate intake which will result in lower blood sugar and higher ketone levels. The chart below explains the ideal ratios. The glucose ketone index is simply a way to measure the relationship between your ketone levels and your glucose levels at any moment in time. It is measured by dividing your blood glucose level (mmol/L) by your blood ketone level (mmol/L). The result is a single number we can use an indicator of one’s metabolic state. The index has its roots in brain cancer treatment, where researchers using metabolic therapy found best results when glucose and ketones maintained a very precise relationship in the patient [1]. Since there are many aspects of daily life (stress, exercise, nutrition etc.) that can upset glucose or ketone levels in the body, thereby throwing off the optimal glucose-ketone ratio, the index was developed to ensure both metrics (glucose and ketones) are maintaining the ideal ratio for optimal treatment outcomes. [ … Read More … ] I tend to stay in a solid level of ketosis most of the day and cycle out for just two hours. Using my numbers from the photo above look like: Convert Blood Glucose – 85 mg/dL / 18 = 4.72 mmol/L Divide Glucose by Ketones – 4.72 mmol/L / 1.6 mmol/L = 2.95 GKI No Comments No comments yet. Sorry, the comment form is closed at this time. Continue reading >>

The Glucose-ketone Index Approach To Cancer Therapy Some Early Insights

The Glucose-ketone Index Approach To Cancer Therapy Some Early Insights

The Glucose-Ketone Index Approach to Cancer Therapy Some Early Insights Written by Chris on June 01, 2015 No comments This recent article appeared in March 2015. Thomas Seyfried and colleagues came up with a way to monitor the therapeutic efficacy for managing brain cancer by introducing the glucose ketone index. This tool measures the ratio of blood glucose to ketones (BOHB) and its helpful because it outputs a single number that would tell if a patient is predominantly burning ketones or glucose. It would assess whether the patient is successful into implementing a ketogenic dietary approach (or a fasting approach) to managing different pathological conditions. The Glucose Ketone Index (GKI) was created to track the zone of metabolic management for brain tumor management. The GKI is a biomarker that refers to the molar ratio of circulating glucose over -OHB, which is the major circulating ketone body. A mathematical tool called the Glucose Ketone Index Calculator was developed that can calculate the GKI and monitor changes in this parameter on a daily basis. The GKIC generates a single value that can assess the relationship of the major fermentable tumor fuel (glucose) to the non-fermentable fuel (ketone bodies). The formula is quite comprehensive and it can be used with different unit systems and devices: The graphics above show you how you can switch between mg/dL and mM (millimolar). So, far theyve used the calculator to estimate the GKI for mice and humans with brain tumors that were treated with either calorie restriction or ketogenic diets from five previously published reports.[1] They noticed that the optimal results in terms of the efficacy of the treatment would be when GKI was around 1, or lower. I suspect that lower than 1 would be even better. This would Continue reading >>

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer Background:Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic fermentation of glucose (Warburg effect), which is the common metabolic malady of most cancers including brain tumors. The KD targets tumor energy metabolism by lowering blood glucose and elevating blood ketones (-hydroxybutyrate). Brain tumor cells, unlike normal brain cells, cannot use ketone bodies effectively for energy when glucose becomes limiting. Although plasma levels of glucose and ketone bodies have been used separately to predict the therapeutic success of metabolic therapy, daily glucose levels can fluctuate widely in brain cancer patients. This can create difficulty in linking changes in blood glucose and ketones to efficacy of metabolic therapy.Methods:A program was developed (Glucose Ketone Index Calculator, GKIC) that tracks the ratio of blood glucose to ketones as a single value. We have termed this ratio the Glucose Ketone Index (GKI).Results:The GKIC was used to compute the GKI for data published on blood glucose and ketone levels in humans and mice with brain tumors. The results showed a clear relationship between the GKI and therapeutic efficacy using ketogenic diets and calorie restriction.Conclusions:The GKIC is a simple tool that can help monitor the efficacy of metabolic therapy in preclinical animal models and in clinical trials for malignant brain cancer and possibly other cancers that express aerobic fermentation. Continue reading >>

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