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Euglycemic Ketoacidosis Definition

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high blood sugar, low blood pH, and ketoacids in either the blood or urine. The primary treatment of DKA is with intravenous fluids and insulin. Depending on the severity, insulin may be given intravenously or by injection under the skin. Usually potassium is also needed to prevent the development of low blood potassium. Throughout treatment blood sugar and potassium levels should be regularly checked. Antibiotics may be required in those with an underlying infection. In those with severely low blood pH, sodium bicarbonate may be given; however, its use is of unclear benefit and typically not recommended. Rates of DKA vary around the world. About 4% of people with type 1 diabetes in United Kingdom develop DKA a year, while in Malaysia the condition affects about 25% a year. DKA was first described in 1886 and, until the introduction of insulin therapy in the 1920s, it was almost universally fatal. The risk of death with adequate and timely treatment is currently around 1–4%. Up to 1% of children with DKA develop a complication known as cerebral edema. The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. Those who measure their glucose levels themselves may notice hyperglycemia (high blood sugar levels). In severe DKA, breathing becomes labored and of a deep, gasping character (a state referred to as "Kussmaul respiration"). The abdomen may be tender to the point that an acute abdomen may be suspected, such as acute pancreatitis, appendicitis or gastrointestinal perforation. Coffee ground vomiting (vomiting of altered blood) occurs in a minority of people; this tends to originate from erosion of the esophagus. In severe DKA, there may be confusion, lethargy, stupor or even coma (a marked decrease in the level of consciousness). On physical examination there is usually clinical evidence of dehydration, such as a dry mouth and decreased skin turgor. If the dehydration is profound enough to cause a decrease in the circulating blood volume, tachycardia (a fast heart rate) and low blood pressure may be observed. Often, a "ketotic" odor is present, which is often described as "fruity", often compared to the smell of pear drops whose scent is a ketone. If Kussmaul respiration is present, this is reflected in an increased respiratory rate.....

Euglycemic Diabetic Ketoacidosis, A Misleading Presentation Of Diabetic Ketoacidosis

Go to: Introduction Hyperglycemia and ketosis in diabetic ketoacidosis (DKA) are the result of insulin deficiency and an increase in the counterregulatory hormones glucagon, catecholamines, cortisol, and growth hormone. Three processes are mainly responsible for hyperglycemia: increased gluconeogenesis, accelerated glycogenolysis, and impaired glucose utilization by peripheral tissues. This might also be augmented by transient insulin resistance due to hormone imbalance, as well as elevated free fatty acids.[1] DKA is most commonly precipitated by infections. Other factors include discontinuation of or inadequate insulin therapy, pancreatitis, myocardial infarction, cerebrovascular accident, and illicit drug use. The diagnostic criteria of DKA, established by the American Diabetic Association, consists of a plasma glucose of >250 mg/dL, positive urinary or serum ketones, arterial pH of <7.3, serum bicarbonate <18 mEq/L, and a high anion gap. The key diagnostic feature of DKA is elevated circulating total blood ketone concentration. Hyperglycemia is also a key diagnostic criterion of DKA; however, a wide range of plasma glucose levels can be present on admission. Continue reading >>

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Popular Questions

  1. Jacob4Jesus

    I am considering getting a home meter to test my glucose and ketone levels. The meter’s are reasonably priced but test strips on Amazon are about $1 for glucose and $3 for ketones.
    I know what levels to look for and all that. But my question is how important is home testing and if it is important then how often should I do it?

    –Jacob

  2. Shortstuff

    In my over two years on keto, I’ve only been testing for the last couple of months. It’s really not essential if you’re seeing the results you want, but is a useful tool if not.

    I only started testing because I was curious.

  3. KHAN

    I think if you are don’t need to test for ketones for health reasons, it’s a huge waste of money.
    If you’re diabetic or pre-diabetic, testing for blood sugar is very important. Especially if you’re tying to ween yourself off medication.

    If your a1c is normal, I wouldn’t bother.

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Euglycemic Diabetic Ketoacidosis: A Potential Complication Of Treatment With Sodium–glucose Cotransporter 2 Inhibition

OBJECTIVE Sodium–glucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ketoacidosis (euDKA) in hopes that it will enhance recognition of this potentially life-threatening complication. RESEARCH DESIGN AND METHODS Cases identified incidentally are described. RESULTS We identified 13 episodes of SGLT-2 inhibitor–associated euDKA or ketosis in nine individuals, seven with type 1 diabetes and two with type 2 diabetes, from various practices across the U.S. The absence of significant hyperglycemia in these patients delayed recognition of the emergent nature of the problem by patients and providers. CONCLUSIONS SGLT-2 inhibitors seem to be associated with euglycemic DKA and ketosis, perhaps as a consequence of their noninsulin-dependent glucose clearance, hyperglucagonemia, and volume depletion. Patients with type 1 or type 2 diabetes who experience nausea, vomiting, or malaise or develop a metabolic acidosis in the setting of SGLT-2 inhibitor therapy should be promptly evaluated for the presence of urine and/or serum ketones. SGLT-2 inhibitors should only be used with Continue reading >>

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Popular Questions

  1. cobracock1979

    Hi Bros,
    Im on a CKD diet - only carbs I have is 20mg oats PWO + veg and a carb Bulking day once a week.
    I find I tend to go into Ketosis after eating High fats (ie nuts) but I never seem to go fully into Ketosis, only half way (I use Ketostix to tell).
    Anyone have any other methods to kick start ketosis/ supplements to help insulin etc?
    Thanks in advance

  2. GUARDIAN

    have u gone 2 straight strict weeks yet without a carb up day?

  3. cobracock1979

    Quote posted by GUARDIAN
    have u gone 2 straight strict weeks yet without a carb up day? Been on for 3 weeks - 2 weeks straight then 1 carb up day last week. I just got some ALA as well

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Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Lowering your caloric intake and doing intermittent fasting has a ton of health benefits on both your body and your mind. Herman Hesse said in his novel, Siddhartha: Everyone can perform magic, everyone can reach his goals, if he is able to think, if he is able to wait, if he is able to fast. Numerous studies have shown that caloric restriction increases the lifespan and youthfulness of almost all species, starting with fruit flies and ending with rhesus monkeys. In humans, there is no definite anti-aging proof but fastings been shown to improve biomarkers, reduce inflammation, promote stem cell growth, boost the immune system and make you burn a ton of fat. However, the key to successfully gaining these health benefits comes from avoiding malnutrition and starvation. Theres a hugedifference between fasting, starvationand caloric restriction, but it doesn't mean you can't be starving while intermittent fasting or consuming fewer calories. This video tells you how to avoid starvation mode while fasting and gain the longevity benefits More In-Depth video on autophagy: https://www.youtube.com/watch?v=_2kW_... Read the blog post for the referred studies: http://siimland.com/physiology-of-fas... Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Keto//IF: HTTP://www.siimland.com/keto-if-fasting/ Stay Empowered Siim Join my Facebook group: https://www.facebook.com/groups/bodym... What is this awesome ring I'm wearing?: https://www.youtube.com/watch?v=399Xt... Use the code SIIMLAND to get -20% from Perfect Keto exogenous ketones: http://bit.ly/2gvn88m #fasting #intermittentfasting #weightloss #fatloss #burnfat #loseweight #losefat #keto Disclaimer I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only. Follow me on social media: Blog: http://siimland.com Facebook: https://www.facebook.com/thesiimland/ My Facebook Group: https://www.facebook.com/groups/bodym... Instagram: https://www.instagram.com/siimland/ Twitter: https://twitter.com/inthevanguard Pinterest: https://www.pinterest.com/siimland/ Patreon: https://www.patreon.com/siimland

Starvation-induced True Diabetic Euglycemic Ketoacidosis In Severe Depression

Go to: A 34-year-old man with a 19-year history of type 1 diabetes presented as an emergency with a 4-day history of nausea, vomiting, and flu-like symptoms. He was on a basal bolus insulin regime comprising 8 units of bolus insulin lispro injected at mealtimes and 12 units of basal isophane insulin at bedtime, but did not monitor capillary blood glucose levels. He did however empirically increase his insulin doses during times of illness and had increased his isophane insulin to 15 units during the 3 days prior to presentation. He had only one prior hospital admission, which occurred 6 years previously and was due to an episode of DKA precipitated by gastroenteritis. He was single, unemployed, did not drink alcohol, had no previous psychiatric history, no family history of diabetes or other medical conditions, and lived in a hostel. He had a record of poor clinic attendances and a history of long-term cannabis use. He denied any salicylate consumption, but admitted to some weight loss; however, he was unable to quantify this. His body mass index (BMI) was 19 kg/m2, and he looked unkempt. Physical examination revealed a temperature of 36.4°C (97.5°F), heart rate of 106 beats per Continue reading >>

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Popular Questions

  1. Liam Gorman

    I agree with Anderson. It is a sad fact, however it is a harsh reality and we should accept violence can often only be the only answer to resolving an issue.
    Many would combat this point by saying peace is the way forward and a peaceful resolution is the best answer- it can often be this way, sadly it isn't always.
    If Anders Behring Breivik had been met with gunfire as he arrived on Utøya island lots of lives would have been saved that day.
    I know, for a certainty, that this is my view on the matter however I guess there would be many so opposed to murder, however justifiable, that they'd sooner stand up to talk them down and be shot trying.
    I think this question could be answered by posing a question along the lines of "If an armed madman broke into your child's school whilst you where there, and you had a gun at your disposal, what would you do?" I think that's a scenario which brings reason to my answer.
    So yes. I think that violence can sometimes only be resolved by violence. Obviously the less violent caused is best, but the world can be cruel that way, sometimes there can be no better way to put a cease to a horribly violent occurrence than by stamping it away with violence in return.
    Some may see it as unreasonable, but I think when it's the only possible way to end a situation like those mentioned above, with an unreasonable force, then yes, it's reasonable and justified.

  2. Ranjan Prithvi

    Absolutely. Violence is and should be the only answer to violence.
    But the important question is towards whom?
    Atleast where I live, Many people interpret this as retaliation towards the community of the people who initiated the attack, even if they had nothing to do with it. This is a very wrong interpretation of revenge directed at innocent people in the search for an immediate solace. A heat of the moment act committed and fuelled by a section of the society who perpetuate hatred in the name of revenge and protecting the interests of the community, as finding the actual culprits would be time and resource consuming

  3. Sam Morningstar

    Is there a supposition that humans, as a species, are not inherently violent?
    I don't think it is possible to exclude from this debate the causes of violence and how it manifests in our species. This is the primary flaw in pacifist arguments.
    One human inflicting violence on another will normally be for a specific purpose. Whether the intent is to kill, hurt or intimidate, it usually represent eliminating threats, gaining positions of power or asserting dominance (which might manifest as simply enjoying the power and thrill associated with the act of killing).
    In some cases, it represents an animal (yes, a human animal) that has some mental or psychological defect that causes erratic and dangerous behavior. In these instances, a violent outburts cannot be "resovled" in a way that is acceptable to any rational human being. And even in the case where there is no aberrational issues invovled, and we are talking about NORMAL violent human behavior, you will have one group of people or certain individuals that can and will resort to violence for a variety of reasons. If you set up the environment in a certain way, it is an inevitability. This is the pathology of our species.
    If thy reason for the violence is to intimidate and control, then sure...some people might be okay with being in a subservient or inferior role, being dominated by others. This might be seen as an acceptible compromise or "resolution" to avoid any further violence. However, there is a cost benefit analysis that has to be done. Once a violent act is being engaged in, the person being attacked has to understand the underlying causes and recognize what the possible outcomes will be.
    Of course there are violent situations that will have unacceptable outcomes ...that any moral, ethical, and rational person will not be able to tolerate (mainly, death of your loved ones or the utter destruction of your nation). In these cases, the laws of inertia apply. An opposing force must be applied.
    By the way, I do not consider theoretical or religious pacifism to be rational.Theoretical pacifists do not apply the laws of nature and have usually never seen violence actually threaten them personally. These folks would change their tune quickly if they were facing a real violent threat. And religious pacifists are not rational because they believe there is something beyond this mortal existence on planet earth. So, they ignore reality altogether and choose a fantastic degree of nihilism.

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