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Euglycemic Ketoacidosis

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Euglycemic Diabetic Ketoacidosis: A Potential Complication Of Treatment With Sodiumglucose Cotransporter 2 Inhibition

Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With SodiumGlucose Cotransporter 2 Inhibition We are experimenting with display styles that make it easier to read articles in PMC. The ePub format uses eBook readers, which have several "ease of reading" features already built in. The ePub format is best viewed in the iBooks reader. You may notice problems with the display of certain parts of an article in other eReaders. Generating an ePub file may take a long time, please be patient. Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With SodiumGlucose Cotransporter 2 Inhibition Anne L. Peters, Elizabeth O. Buschur, [...], and Irl B. Hirsch Sodiumglucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ketoacidosis (euDKA) in hopes that it will enhance recognition of this potentially life-threatening complication. Cases identified incidentally are described. We identified 13 episodes of SGLT-2 inhibitorassociated euDKA or ketosis in nine individuals, seven with type 1 diabetes and two with type 2 diabetes, from various pract Continue reading >>

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  1. ruford

    is this what they mean when they say keto?
    B
    2 eggs 1 carb
    fried in butter 0 grams carbs
    S
    1 oz almonds 3 grams carbs
    L
    5 oz chicken 0 carbs
    2 oz pecans 4 carbs
    s
    2 oz cheese 2 carbs
    D
    5 oz ground beef 0 carbs
    2 oz walnuts 2 grams carbs
    1/2 cup brussel sprouts 5 grams carbs
    s
    2 oz cheese 2 grams carbs
    19 grams total

  2. bulkbiker

    Kind of although most keto dieters don't snack and quite a few don't eat three meals a day...
    I'm guessing that as you are in Canada those are total carbs?
    In the UK our measurements are usually net so depending on how low you want to go I try for less than 20 net carbs a day but am usually lower.
    Hope that helps

  3. Brunneria

    Hi,
    Keto is any way of eating (or not eating) that means the body switches from glucose burning to fat burning. And that usually happens for people when they eat somewhere below 50g carbs a day.
    However, it is worth bearing in mind, that protein can be converted to glucose by the body, via a process called gluconeogenesis. This happens if we eat more protein than we need to use for protein-purposes, then the spare will be broken down and may release glucose via gluconeogenesis.
    I don't know your height, weight and activity levels, so i can't say how much protein you need - but there are lots of protein calculators online, where you can check if you want. For me, the amount of protein on that menu would be high enough to prevent ketosis, and the small amount of veg would leave me constipated.
    Doesn't mean that will happen to you, since we are all different, but it might be worth you doing a bit of trial and error to see how your body handles more or less of the different macronutrients. But a ketogenic diet isnt a high protein diet.
    Are you testing for ketones?
    If you want a programme of really delicious, varied, interesting meals, then have a look at the 2 week Keto Challenge, on the www.dietdoctor.com website. It demonstrates just how high we can go on the fat, rather than the protein.
    Hope that helps.

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Euglycemic Diabetic Ketoacidosis: A Potential Complication Of Treatment With Sodiumglucose Cotransporter 2 Inhibition

Objective Sodiumglucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ketoacidosis (euDKA) in hopes that it will enhance recognition of this potentially life-threatening complication. Research Design and Methods Cases identified incidentally are described. Results We identified 13 episodes of SGLT-2 inhibitorassociated euDKA or ketosis in nine individuals, seven with type 1 diabetes and two with type 2 diabetes, from various practices across the U.S. The absence of significant hyperglycemia in these patients delayed recognition of the emergent nature of the problem by patients and providers. Conclusions SGLT-2 inhibitors seem to be associated with euglycemic DKA and ketosis, perhaps as a consequence of their noninsulin-dependent glucose clearance, hyperglucagonemia, and volume depletion. Patients with type 1 or type 2 diabetes who experience nausea, vomiting, or malaise or develop a metabolic acidosis in the setting of SGLT-2 inhibitor therapy should be promptly evaluated for the presence of urine and/or serum ketones. SGLT-2 inhibitors should only be used with grea Continue reading >>

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  1. [deleted]

    Pure frustration. My poor wife who just wants to lose 20 lbs. I've tolder her that keto is THE way to go. I told her I was certain that she would drop at least 5 lbs the first month. She used to eat low fat yogurt with bannanas and blueberries every morning. Whe used to have mexican food all the time with lots of tortillas. She used to have ice cream every night. She LOVES that food, but on my advice, gave it up and went strict keto, and a lot less calories too. And she hansn't dropped anounce in 5 weeks. Last night she said, "there's no point in me doing this any more. I guess I'm just one of those people who just can't lose weight. It's hereditary. My mom has a big tummy, so does my sister. I do too. We just get fat around the middle and that's the way it is". Her friends said "ketosis toomuch fat. It's unhealthy. Eating all that fat, you'll nevr lose weight". Reddit says "just ignor them and let the results speak for themselves". But, no results. Her friends, who starve themselves and count calories, are losing. 5 lbs in one week. I guess they are right. I know we are doing it right. I am very knowlegable about keto. Been doing it for years. I took off 30 lbs without even trying.
    She needs encouragment. Keto is NOT working. EDIT 7-8-17: Breakfast: one sausage patty. One egg scrambled in butter. This is a typical breakfast for her. EDIT: 235 calories with the teaspoon of butter, not 200 as originally posted. 0 carbs. EDIT: 7-8-17. Some stats: She is 5'10" tall. About 148lbs. All weight is around her middle. She is skinney everywhere else. All weight is in "rolls" around her bra area and stomach. EDIT 7-8-17: LNCH 1/2 avacdo (161 cal) . two teaspoons of tuna salad (70 cal). Total of 231cal. 6 carbs. EDIT 7-8-17 DINNER: 2 scrambled aggs (150) with 2/3 avacado (175): Total 325. 0 carbs. DAILT TOTAL: 791. This is a pretty typical day for her, although dinner varies up to 500 calories. She is under 1000 a day. And yet...

  2. drinkduff77

    I'll say it since no one else has...she could very well be sneaking food that you don't know about.

  3. GodricGryffindor87

    I thought this but didn't want to say it. I know people who have been discouraged and quit their diet only to admit later down the road they were cheating during the diet.

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Several metals, including iron, cobalt, copper and zinc, are naturally present in living organisms and play essential roles in a wide range of biological processes. In addition, some metal complexes have shown to be very successful therapeutic and diagnostic agents. Examples of these are platinum-based anticancer drugs, used in chemotherapy since the 1970s, and gadolinium-based MRI contrast agents for medical imaging. For several years Ramon Vilar and his team have been studying the chemistry of metal complexes in living organisms with the aim of developing new metal-based drugs as well as gaining a better molecular understanding of biological processes. They have a particular interest in studying how novel metal complexes interact with selected enzymes and DNA. For more information please visit http://www3.imperial.ac.uk/newsandeve...

Euglycemic Diabetic Ketoacidosis: A Diagnostic And Therapeutic Dilemma

Euglycemic diabetic ketoacidosis: a diagnostic and therapeutic dilemma 1Department of Internal Medicine, Memorial Hospital of Martinsville and Henry County, Martinsville, Virginia, USA, 2Texas Tech University Health Sciences Center, El Paso, Texas, USA, 3Senior Research Associate, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA, 4Department of Pharmacology, St Johns Medical College, Bangalore, India, Received 2017 Jul 18; Accepted 2017 Aug 4. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License . Euglycemic diabetic ketoacidosis (EDKA) is a clinical triad comprising increased anion gap metabolic acidosis, ketonemia or ketonuria and normal blood glucose levels <200 mg/dL. This condition is a diagnostic challenge as euglycemia masquerades the underlying diabetic ketoacidosis. Thus, a high clinical suspicion is warranted, and other diagnosis ruled out. Here, we present two patients on regular insulin treatment who were admitted with a diagnosis of EDKA. The first patient had insulin pump failure and the second patient had urinary tract infection and nausea, thereby resulting in starvation. Both Continue reading >>

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  1. Binti1962

    Does it matter when to test blood ketones?

    Just received a new blood ketone meter and the strips are arriving today so I haven't used it yet. Does it matter when I test? There were no guidelines with the meter. Thanks!
    Binti
    Sent from my iPhone using Diabetes Daily

  2. jwags

    I bought a ketone meter several years ago. I would test in the mornings once or twice a week. The strips are very expensive. I finally gave up because my ketone level was always very low, even doing a Ketogenic diet.

  3. furball64801

    Are you on a ketogenic diet to see if you are burning fat. You can get urine sticks that would do about the same job and are cheaper. I used those 45 yrs ago before I became diabetic and lost 10 lbs but was only 170 at the time.

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