Euglycemic Dka Medscape

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Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor Inhibitors of sodiumglucose cotransporter 2 (SGLT2) decrease plasma glucose by blocking the reabsorption of glucose at the proximal tubule.1,2 Case reports have suggested that SGLT2 inhibitors may be associated with an increased risk of diabetic ketoacidosis, which led to a warning from the Food and Drug Administration (FDA) in May 2015.3,4 The objective of our study was to assess the risk of diabetic ketoacidosis after the initiation of an SGLT2 inhibitor. https://www.youtube.com/channel/UCsqm...

Sglt2 Inhibitor-linked Diabetic Ketoacidosis Is Rare, But Severe

SGLT2 Inhibitor-Linked Diabetic Ketoacidosis Is Rare, but Severe Many cases of sodium-glucose cotransporter-2 (SGLT2) inhibitor-associated diabetic ketoacidosis (DKA) are preventable, new research suggests. But physicians and patients are missing the signs and symptoms of this rare side effect or not even aware of the link and as a result, any cases are severe and one was fatal, according to this latest audit of Australian databases, published online February 13 in Diabetes Care by Emily J Meyer, MBBS, of the Royal Adelaide Hospital and University of Adelaide, Australia, and colleagues. As DKA was initially missed by both patients and physicians, likely due in part to relative euglycemia, this led to delayed treatment, say the researchers. However, "identifiable precipitants were often present, suggesting the potential for risk mitigation," Meyer and colleagues write. Stop SGLT2 Inhibitors for Acute Illness, Surgery The US Food and Drug Administration (FDA) first warned about the risk for DKA with SGLT2 inhibitors, a relatively new class of oral agents for type 2 diabetes, in 2015, and the European Medicines Agency followed suit in 2016. The phenomenon has also been reported sever Continue reading >>

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  1. Kok-Hong Wong

    The fear of ketosis turning into ketoacidosis leads to nutritional advice that favours constant grazing. Eating small meals every few hours. This keeps a constantly elevated insulin level that suppresses enzymes necessary for fats oxidation. So the body is perpertually in a fats storage mode rather than fats burning mode.

  2. Rajagopalan K

    Hemoglobin A1c is good marker of long-term control of diabetes and a value below 7 is recommended. Tight control of diabetes with diet, oral medications or insulin and exercise along with early recognition and treatment of complications are the ways to keep it in check.

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Get Unlimited Access On Medscape.

You’ve become the New York Times and the Wall Street Journal of medicine. A must-read every morning. ” Continue reading >>

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Popular Questions

  1. LindseysMommy

    Sometimes when I tell someone about my Keto choices their response is "Oh! So it's like Atkins then!" Since I don't know a thing about Atkins I don't know how to explain the differences. I know it's not the same but I don't know how to clear up this misconception. How do I differentiate what Keto is over Atkins?

  2. WillowWagner

    Keto essentially is the induction phase of Atkins, with protein a little more limited. More science has been done so things have been tweaked a little. "A New Atkins for a New You" was written by Volek, Phinney and Westman... all three are major advocates for keto.

  3. chrisbair

    I always say, "yeah, kinda like Atkins, but with science!"

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Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Lowering your caloric intake and doing intermittent fasting has a ton of health benefits on both your body and your mind. Herman Hesse said in his novel, Siddhartha: Everyone can perform magic, everyone can reach his goals, if he is able to think, if he is able to wait, if he is able to fast. Numerous studies have shown that caloric restriction increases the lifespan and youthfulness of almost all species, starting with fruit flies and ending with rhesus monkeys. In humans, there is no definite anti-aging proof but fastings been shown to improve biomarkers, reduce inflammation, promote stem cell growth, boost the immune system and make you burn a ton of fat. However, the key to successfully gaining these health benefits comes from avoiding malnutrition and starvation. Theres a hugedifference between fasting, starvationand caloric restriction, but it doesn't mean you can't be starving while intermittent fasting or consuming fewer calories. This video tells you how to avoid starvation mode while fasting and gain the longevity benefits More In-Depth video on autophagy: https://www.youtube.com/watch?v=_2kW_... Read the blog post for the referred studies: http://siimland.com/physiology-of-fas... Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Keto//IF: HTTP://www.siimland.com/keto-if-fasting/ Stay Empowered Siim Join my Facebook group: https://www.facebook.com/groups/bodym... What is this awesome ring I'm wearing?: https://www.youtube.com/watch?v=399Xt... Use the code SIIMLAND to get -20% from Perfect Keto exogenous ketones: http://bit.ly/2gvn88m #fasting #intermittentfasting #weightloss #fatloss #burnfat #loseweight #losefat #keto Disclaimer I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only. Follow me on social media: Blog: http://siimland.com Facebook: https://www.facebook.com/thesiimland/ My Facebook Group: https://www.facebook.com/groups/bodym... Instagram: https://www.instagram.com/siimland/ Twitter: https://twitter.com/inthevanguard Pinterest: https://www.pinterest.com/siimland/ Patreon: https://www.patreon.com/siimland

Starvation-induced True Diabetic Euglycemic Ketoacidosis In Severe Depression

Go to: A 34-year-old man with a 19-year history of type 1 diabetes presented as an emergency with a 4-day history of nausea, vomiting, and flu-like symptoms. He was on a basal bolus insulin regime comprising 8 units of bolus insulin lispro injected at mealtimes and 12 units of basal isophane insulin at bedtime, but did not monitor capillary blood glucose levels. He did however empirically increase his insulin doses during times of illness and had increased his isophane insulin to 15 units during the 3 days prior to presentation. He had only one prior hospital admission, which occurred 6 years previously and was due to an episode of DKA precipitated by gastroenteritis. He was single, unemployed, did not drink alcohol, had no previous psychiatric history, no family history of diabetes or other medical conditions, and lived in a hostel. He had a record of poor clinic attendances and a history of long-term cannabis use. He denied any salicylate consumption, but admitted to some weight loss; however, he was unable to quantify this. His body mass index (BMI) was 19 kg/m2, and he looked unkempt. Physical examination revealed a temperature of 36.4°C (97.5°F), heart rate of 106 beats per Continue reading >>

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  1. j

    Keto diet while nursing

    My SIL is doing the Ketogenic Diet (low carb/high fat) and is having great results. I was overweight before getting pregnant, and now have even more to lose. I'm thinking of trying the diet but am wondering how it will affect breastfeeding. I've heard it might not be good for baby if your body is in ketosis, but I'm having a hard time finding solid info either way. Anyone have any experience with this?

  2. Mareeena

    I'm doing something similar but a breastfeeding friendly variation... Basically Atkins 20 is not safe for breastfeeding but Atkins 40 is. I think it's important while nursing to eat balanced so I still eat the recommended servings of fruit a day and some whole grains. I try for lower sugar fruits like berries. For grains I do oats and then a small bowl of kashi go lean cereal (the cinnamon crunch kind is amazing)
    So basically I try and eat balanced for the sake of my milk and just reduce my net carbs while trying to eat as much protein and fiber as possible.
    As for your question is keto specifically safe? I don't personally think so.
    I'm not counting carbs and I'm eating a good amount of fat (meats, eggs, cheese)

    I've lost 7lbs the past 9 days and haven't exercised much during that time (baby is teething I'm tired)

  3. Mareeena

    Sorry when I said I'm not counting carbs I meant I'm not counting calories!!'

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