Euglycemic Dka Invokana

Share on facebook

What is DIABETIC CARDIOMYOPATHY? What does DIABETIC CARDIOMYOPATHY mean? DIABETIC CARDIOMYOPATHY meaning - DIABETIC CARDIOMYOPATHY definition - DIABETIC CARDIOMYOPATHY explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic cardiomyopathy is a disorder of the heart muscle in people with diabetes. It can lead to inability of the heart to circulate blood through the body effectively, a state known as heart failure, with accumulation of fluid in the lungs (pulmonary edema) or legs (peripheral edema). Most heart failure in people with diabetes results from coronary artery disease, and diabetic cardiomyopathy is only said to exist if there is no coronary artery disease to explain the heart muscle disorder. One particularity of DCM is the long latent phase, during which the disease progresses but is completely asymptomatic. In most cases, DCM is detected with concomitant hypertension or coronary artery disease. One of the earliest signs is mild left ventricular diastolic dysfunction with little effect on ventricular filling. Also, the diabe

A Case Of Euglycemic Diabetic Ketoacidosis Due To Canagliflozin Complicated By Takotsubo Cardiomyopathy

A Case of Euglycemic Diabetic Ketoacidosis due to Canagliflozin Complicated by Takotsubo Cardiomyopathy Muzammil Khan , Shaza Khalid, Asghar Marwat, Hassan Mehmood American Journal of Medical Case Reports. 2018, 6(1), 1-3. DOI: 10.12691/ajmcr-6-1-1 Sodium-glucose co-transporter-2 (SGLT-2) inhibitor is the latest class of anti diabetic medication that improves glycemic control in insulin independent fashion by increasing urinary loss of filtered glucose. Since its introduction in 2013, several cases of euglycemic DKA have been reported in patients being treated with SGLT-2 inhibitors. Blood glucose levels in range lower than expected for DKA makes the diagnosis challenging if clinical suspicion for euglycemic DKA is not high. We report a case of a patient being treated with canagliflozin who presented with DKA, AKI and mild hyperglycemia that was complicated by stress-induced cardiomyopathy. Keywords: sodium-glucose co-transporter-2 (SGLT-2) inhibitor euglycemic DKA In March 2013, first Sodium-glucose co-transporter-2 (SGLT-2) inhibitor, canagliflozin, was approved for the treatment of type 2 diabetes mellitus by the US food and drug agency (FDA) (1). SGLT-2 inhibitors reversibly i Continue reading >>

Share on facebook

Popular Questions

  1. Solieus

    So I bought some "no sugar added" chocolate the other day, and was trying to decode the package info... can anyone help?
    It's this: http://www.ohnuts.com/buy.cfm/no-sugar-added-milk-chocolate-bar-with-praline
    Ingredients: Isomalt, hazelnuts, cocoa butter, whole milk powder, cocoa mass, vegetable fats, emulsifier (sunflower lecithin), vanilla, sucralose. Milk solids: 20% minimum. Cocoa solids: 30% minimum (milk chocolate)
    Soo the ingredients don't mention any sugar at all but the nutritional info says there is 18g of carbs per 5 squares. 2g sugars, >1g fiber.
    Then there's a table below:
    Avg quantity per serving (33g) 165 cal 2g protein 12g fat Carbs 17g - of which sugars: 2g - of which polyols: 14g - of which assimilable polyols: 9g
    So assimilable means it will be digested and metabolized right? So is the NET carb count 11g, then?
    Thanks guys in advance.

  2. zbeeble42

    Isomalt has a glycemic index of 2, compared to sucrose at 58-65. In other words it has almost no impact on blood sugar. Some portion is considered digestible, which is why it has 2 calories per gram in the USA, and also explains the "assimilable polyols" on your ingredient statement. BUT, and this is the important part, the digestion that does happen is by bacteria in the gut that convert it to short chain fatty acids. So, about half of it will be excreted unchanged and the other half will make it into your bloodstream as fatty acids that will then be converted to ketones. Only a tiny portion makes it into the bloodstream as glucose. There are several high-quality studies on isomalt that support this.
    I count isomalt as 0 carbs for my own purposes because you'd have to eat many grams of isomalt in order to have the same blood sugar impact as one gram of sugar. Since isomalt is the only polyol in that chocolate bar, I would suggest counting one serving as 3g net carbs (17g-14g).

  3. Solieus

    Awesome answer! Wikipedia was vastly lacking in this info. Thanks :)

  4. -> Continue reading
read more
Share on facebook

To watch the full lecture visit: https://bit.ly/2GCpykW About this lecture: Covering reviews of cardiovascular outcome trials, Professor Andrew Krentz focuses on glucose lowering in clinical trials. Professor Krentz discusses updates on hypotheses concerning the mechanism of benefits and risk of EMPA-REG OUTCOME and CANVAS studies, and considers the clinical implications of these trials. This lecture was filmed at the RSM in London for the event 'an update on lipid and glucose lowering clinical trials' on Friday 23rd of February 2018

Euglycemic Diabetic Ketoacidosis With Prolonged Glucosuria Associated With The Sodium-glucose Cotransporter-2 Canagliflozin

Euglycemic Diabetic Ketoacidosis With Prolonged Glucosuria Associated With the Sodium-Glucose Cotransporter-2 Canagliflozin Neda Rasouli, MD, University of Colorado Denver, Mail Stop 8106, 12631 East 17th Avenue, Aurora, CO 80045, USA. Email: [email protected] Received 2017 Mar 15; Revised 2017 May 5; Accepted 2017 May 9. Copyright 2017 American Federation for Medical Research This article is distributed under the terms of the Creative Commons Attribution 4.0 License ( ) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ( ). Sodium-glucose cotransporter-2 (SGLT2) inhibitors improve glycemic control by a reversible inhibition of the sodium-glucose cotransporters in the renal proximal tubules resulting in increased urinary glucose. This unique mechanism, independent of insulin secretion and beta cell function, has made this class of medication desirable in patients with type 2 diabetes. However in May 2015, the US Food and Drug Administration issued a safety warning pertaining to the development of diabetic ketoacidosis (DKA) with the use of SGLT2 Continue reading >>

Share on facebook

Popular Questions

  1. [deleted]

    Ok, so here's a question I have, that I can't find the answer to in the FAQ...
    Once you are fat-adapted, do you intentionally drop your dietary fat intake down and rely on body fat being utilized to make up the difference?
    Are successful Keto diets generally eating a monitored calorie deficit for their fats, or just eating fat to satiety?
    Probably both?
    I understand the first part of the Keto diet for losing fat - get into nutritional ketosis. I just don't understand the second part. I assume that it is possible to overeat fats and put on weight, so do most people still count calories?
    If so, is the major advantage over traditional dieting that it is easier to say no to food Or is it that it that you can maintain energy in a caloric deficit. Edit:Or is it muscle preservation while dieting?
    If this is answered in the FAQ's or elsewhere, thanks in advance for links.

  2. ketogirlde

    Not counting calories is often referred to as "lazy keto" around here, you can search that for experiences. It works best for morbidly obese men - the less you have to lose and the smaller you are, the less leeway you have.
    If so, is the major advantage over traditional dieting that it is easier to say no to food Or is it that it that you can maintain energy in a caloric deficit.
    The latter. Eating low-carb is satiating and it is easier to maintain a deficit without blood sugar ups and downs. This is the case whether or not you count calories. However, for people who don't have a lot to lose, are prone to binge eating, or have a history of food abuse, those satiety effects are often not strong enough to negate the need for counting calories.

  3. Scarykidscaringkids

    Yup, I'm 130 pound and not aiming to lose much more but as I used to have an ED I feel a strong need to count calories still. Not counting can result in bingeing and that scares me. I'm hoping one day to rely completely on just my hunger but I still can't trust it yet.

  4. -> Continue reading
read more
Share on facebook

DKA diabetic ketoacidosis nursing management pathophysiology & treatment. DKA is a complication of diabetes mellitus and mainly affects type 1 diabetics. DKA management includes controlling hyperglycemia, ketosis, and acdidosis. Signs & Symptoms include polyuria, polydipsia, hyperglycemia greater than 300 mg/dL, Kussmaul breathing, acetone breath, and ketones in the urine. Typically DKA treatment includes: intravenous fluids, insulin therapy (IV regular insulin), and electrolyte replacement. This video details what the nurse needs to know for the NCLEX exam about diabetic ketoacidosis. I also touch on DKA vs HHS (diabetic ketoacidosis and hyperosmolar hyperglycemic nonketotic syndrome (please see the other video for more details). Quiz on DKA: http://www.registerednursern.com/diab... Lecture Notes for this video: http://www.registerednursern.com/diab... Diabetes NCLEX Review Videos: https://www.youtube.com/playlist?list... Subscribe: http://www.youtube.com/subscription_c... Nursing School Supplies: http://www.registerednursern.com/the-... Nursing Job Search: http://www.registerednursern.com/nurs... Visit our website RegisteredNurseRN.com for free quizzes, nursing care plans, salary

The Dka That Wasn't: A Case Of Euglycemic Diabetic Ketoacidosis Due To Empagliflozin

The DKA that wasn't: a case of euglycemic diabetic ketoacidosis due to empagliflozin Nellowe Candelario * and Jedrzej Wykretowicz Department of Internal Medicine, Einstein Healthcare Network, Philadelphia, USA *Correspondence address. Department of Internal Medicine, Einstein Healthcare Network, 5501 Old York Road, Philadelphia, PA 19141, USA. Tel: +267-858-5508; E-mail: [email protected] Received 2016 May 14; Revised 2016 Jun 14; Accepted 2016 Jun 16. Copyright The Author 2016. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] This article has been cited by other articles in PMC. Sodium glucose co-transporter (SGLT-2) inhibitor is a relatively new medication used to treat diabetes. At present, the Food and Drug Administration (FDA) has only approved three medications (canagliflozin, dapagliflozin and empagliflozin) in this drug class for the management of Type 2 diabetes. In Continue reading >>

Share on facebook

Popular Questions

  1. Mindset714

    Hey All!! Happy Fourth!
    I was wondering if anyone has any advice or insights on a keto carb up day? Been seeing it a lot on some pages I follow.


  2. JorgePasada


    I was wondering if anyone has any advice or insights on a keto carb up day?

    I've never heard that phrase before, could you explain what it means?

  3. Fiorella

    Wait. What?

    Have no clue what that is. What is the purpose of a carb up on a low carb way of eating? I don't get it.

  4. -> Continue reading
read more

No more pages to load

Related Articles

  • Euglycemic Dka

    Authors: Priyanka Kailash (MS-4, Campbell University School of Osteopathic Medicine), Kevin Weaver, DO (Program Director, Lehigh Valley Health Network), and Krystle Shafer, MD (Attending Physician, York Hospital) // Edited by: Alex Koyfman, MD (@EMHighAK, EM Attending Physician, UT Southwestern Medical Center / Parkland Memorial Hospital) and Brit Long, MD (@long_brit) A 35-year-old male with a past medical history of type 2 diabetes arrives at t ...

    ketosis Apr 2, 2018
  • Euglycemic Dka Pathophysiology

    Background: Diabetic ketoacidosis (DKA) is traditionally defined as a triad of hyperglycemia (>250mg/dL), anion gap acidosis, and increased plasma ketones. There is another entity that providers must be aware of known as euglycemic DKA (euDKA), which is essentially DKA without the hyperglycemia (Serum glucose <200 mg/dL). Euglycemic DKA is a rare entity that mostly occurs in patients with type 1 diabetes, but can possibly occur in type 2 diabetes ...

    ketosis Apr 27, 2018
  • Euglycemic Dka Medscape

    Professor of Pediatric Endocrinology University of Khartoum, Sudan Introduction DKA is a serious acute complications of Diabetes Mellitus. It carries significant risk of death and/or morbidity especially with delayed treatment. The prognosis of DKA is worse in the extremes of age, with a mortality rates of 5-10%. With the new advances of therapy, DKA mortality decreases to > 2%. Before discovery and use of Insulin (1922) the mortality was 100%. E ...

    ketosis Apr 29, 2018
  • Euglycemic Dka Sglt2

    Go to: Case A 51-year-old man with a known history of T2DM and hypertension presented to the emergency department with a 1-week history of malaise, cough, and intermittent shortness of breath. Over the preceding 2 days, he admitted to a history of decreased oral intake and fever, and he had abstained from taking his antihyperglycemic medications (canagliflozin and linagliptin-metformin). He reported 3 episodes of clear emesis the day of his prese ...

    ketosis Apr 27, 2018
  • Invokana Euglycemic Dka

    You’ve become the New York Times and the Wall Street Journal of medicine. A must-read every morning. ” ...

    ketosis Apr 27, 2018
  • Euglycemic Dka Invokana

    Euglycemic diabetic ketoacidosis: a diagnostic and therapeutic dilemma 1Department of Internal Medicine, Memorial Hospital of Martinsville and Henry County, Martinsville, Virginia, USA, 2Texas Tech University Health Sciences Center, El Paso, Texas, USA, 3Senior Research Associate, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA, 4Department of Pharmacology, St Johns Medical College, Bangalore, India, Rece ...

    ketosis Apr 26, 2018

More in ketosis