Etiology Of Diabetic Ketoacidosis

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What Causes Diabetic Ketoacidosis?

Living With Diabetes Starts With Proper Management As a type 1 diabetic I am quite familiar (unfortunately) with the signs and symptoms of diabetic ketoacidosis . Diabeticketoacidosis(DKA) results fromassociated with too little insulin (and usually high blood sugars as well)which leads to the product of organic acids calledketones. Diabetic ketoacidosis is associated with significant disturbances of the bodys chemistry, which resolve with proper therapy. (And lets clear up early that DKA andnutritional ketosis experienced in low-carb diets are two extremely different thingsbut more on that in a different article!) Diabeticketoacidosisusually occurs in people with type 1 diabetes mellitus, but diabetic ketoacidosis can develop in any person with diabetes. Sincetype 1 diabetestypically starts before age 25 years, diabetic ketoacidosis is most common in this age group, but it may occur at any age. Males and females are equally affected. People withtype 1 diabetesdo not have enoughinsulin, a hormone the body uses to break down sugar (glucose) in the blood for energy. When glucose is not available,fat is broken downinstead. As fats are broken down, acids calledketonesbuild up in the bl Continue reading >>

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  1. [deleted]

    So as i'm laying here typing this i'm experiencing insane hot flashes. I especially notice this after I eat any substanstial calories, My feet are sweating and normally i'm fairly cold, so this is weird to me.
    What concerns me though is that it comes in waves and rushes. like hot flashes, it doesn't feel healthy...
    Alot of people share this experience, i've been learning, but no one really seems to understand why.
    So I guess i'm wondering, is anyone else experiencing this? alot of people get colder, ahh. It just makes no sense. >.<

  2. mvadovic

    i just feel warm, i wear short sleeves till the temperature gets below 30.... and i noticed that during any physical activity i sweat much more then before keto

  3. fake_empires

    This is pure speculation, but could you just be feeling "normal" hot?
    I find I'm really sensitive to warmth now. Those highs and crashes of eating carbs made me REALLY cold all the time.
    Now that I'm on keto if the heater is on too high I have to step outside for a bit. Before keto I would eat a huge sugary meal and then want to put on a sweater after cuz I felt that cold, tired, shaky feeling after carb crash.

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Diabetic Ketoacidosis

Etiology In DKA, there is a reduction in the net effective concentration of circulating insulin along with an elevation of counter-regulatory hormones (glucagon, catecholamines, cortisol, and growth hormone). These alterations lead to extreme manifestations of metabolic derangements that can occur in diabetes. The two most common precipitating events are inadequate insulin therapy or infection. Underlying medical conditions such as MI or stroke that provoke the release of counter-regulatory hormones are also likely to result in DKA in patients with diabetes. Drugs that affect carbohydrate metabolism, such as corticosteroids, thiazides, sympathomimetic agents (e.g., dobutamine and terbutaline), and second-generation antipsychotic agents, may participate in the development of DKA. [1] [9] The use of sodium-glucose cotransporter 2 (SGLT-2) inhibitors has also been implicated in the development of DKA in patients with both type 1 and type 2 diabetes. [10] [11] [12] Pathophysiology Reduced insulin concentration or action, along with increased insulin counter-regulatory hormones, leads to the hyperglycemia, volume depletion, and electrolyte imbalance that underlie the pathophysiology of Continue reading >>

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  1. puppydfh

    Where to buy CHEAP ketone strips?

    Ok, i'm ready to make the buy but been looking on Amazon at strips and meters and cant seem to find the right combo. Of course the strips should be Nova if I get a nova meter and same with the prescision or does what type of ketone strips matter with the meter?
    I read someone said they get the ketone strips from Canada for fairly cheap. I called the pharmacy at my clinic and they didnt have a clue as to what I was talking about.
    So I need to know if strips are meter specific or if they can go with any meter and where to buy cheapest strips for blood ketone meter.
    I'm all set and ready to order I just need to know what to order and many thanks!

  2. walkerwally1

    I bought the Precision Xtra meter on Amazon. I think it was around $18. I bought the strips from Buy Precision Xtra Online - Buy Prescriptions Online - Order Medications Online
    at $19.99 for 10 strips. I am sure that the strips are only good for the meters from the same manufactures. That is how they make their money. There is no generic test strip that I am aware of.

  3. Shanny

    I have the Nova Max Plus, and it requires Nova Max Plus ketone strips. My pharmacy has ten ketone strips for $20. I agree with Wally - there's no such thing as a generic strip - neither ketone nor glucose.

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Pathophysiology Of Diabetic Ketoacidosis

Diabetic ketoacidosis is one of the potentially life-threatening acute complications of diabetes mellitus. In the past, diabetic ketoacidosis was considered as the hallmark of Type I diabetes, but current data show that it can be also diagnosed in patients with type II diabetes mellitus. It is often seen among patients who are poorly compliant to insulin administration during an acute illness. It is commonly precipitated by an acute stressful event such as the development of infection leading to overt sepsis, organ infarction such as stroke and heart attack, burns, pregnancy or intake of drugs that affect carbohydrate metabolism such as corticosteroids, anti-hypertensives, loop diuretics, alcohol, cocaine, and ecstasy. The presence of these stressful conditions incite the release of counter-regulatory hormones such as glucagon, catecholamines and growth hormone. These hormones induce the mobilization of energy stores of fat, glycogen and protein. The net effect of which is the production of glucose. As a result of absent or deficient insulin release, diabetic ketoacidosis present with the following metabolic derangements: profound hyperglycemia, hyperketonemiaand metabolic acidosis Continue reading >>

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  1. midnight-eyes

    My husband and I don't drink coffee - never have and aren't really interested in starting (we don't care for the taste). My husband has been drinking Tazo chai tea lattes (Tazo chai concentrate + original soy milk, which has about 36g net carbs) regularly for the caffeine boost it gives him in the morning, however, it doesn't fit into our keto meal-plan. Switching to unsweetened soy barely dents the net carbs, as most of the sugar comes from the chai concentrate itself.
    We both agree that the flavour of normal brewed tea isn't to our taste (too bitter usually). He also doesn't find that brewed tea offers enough caffeination and usually takes too long to make in the morning.
    The Tazo chai is something we actually bought at Costco - it's the same concentrate Starbucks uses but for way cheaper than buying it in the shop. We both like the flavour of it and he particularly likes the caffeine.
    Any suggestions for alternatives? Additionally, neither of us is interested in drinking diet Coke or Red Bull in the morning either.

  2. amp13

    get some caffeine pills and drink whatever you find tasty+keto friendly. pills are way cheaper than any drink if you're just seeking a caffeine boost

  3. deathmangos

    Second this - cheapest and most flexible option by far. Add some theanine too, goes great with caff.

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