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Do Ketones Cause Kidney Failure?

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Diabetes Dictionary: K

Ketoacidosis Ketones (Ketone Bodies) Chemicals that the body makes when there is not enough insulin in the blood and it must break down fat for its energy. Ketone bodies can poison and even kill body cells. When the body does not have the help of insulin, the ketones build up in the blood and then "spill" over into the urine so that the body can get rid of them. The body can also rid itself of one type of ketone, called acetone, through the lungs. This gives the breath a fruity odor. Ketones that build up in the body for a long time lead to serious illness and coma. See also Diabetic ketoacidosis and Ketones in Wikipedia. Ketonuria Having ketone bodies in the urine; a warning sign of diabetic ketoacidosis (DKA). Ketosis A condition of having ketone bodies build up in body tissues and fluids. The signs of ketosis are nausea, vomiting, and stomach pain. Ketosis can lead to ketoacidosis. Ketotic Hypoglycemia A poorly-understood disorder of childhood, marked by hypoglycemia and ketosis. There is carbohydrate deprivation, with consequent dependence on fat stores for energy. Ketotic hypoglycemia can often be effectively treated by simple dietary changes involving frequent feedings of car Continue reading >>

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Popular Questions

  1. NicoleAnn

    Ketones and Unrinary Tract Infection

    Is it normal when you have a high level of ketone's in your system to get a urinary tract infection? I'm kinda wondering about it, since my doctor doesn't listen to me when I say I have ketone's and he gives me antibiotics for a urinary tract infection. Any help would be greatly appreciated.

  2. MarkM

    Infections are not caused by ketones. But they are encouraged by the high blood sugar that often accompanies ketones. Bacteria love warm moist places where there are lots of nutrients. If you lower your blood sugar to the point there is no longer sugar in your urine, you will be removing one of the key attractions. And hopefully you won't get so many infections. But until this happens, you are going to have to use antibiotics ... .

  3. Kaki

    I already commented on your blog this morning regarding ketones, as an individual who has had many UTI's, women know when they have an infection, as its not possible to urinate without that burning sensation, which we do not tolerate very well and will send you immediately to your doctor for medication to resolve a UTI, you made no mention as to whether you did in fact give your doctor a urine specimen.

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Acute Renal Failure Due To Gabapentin. A Case Report And Literature Review

Fracaso renal agudo por gabapentina. Descripción de un caso y revisión de la literatura Gabapentin is an anticonvulsive that is widely used for a number of indications at present: diabetic neuropathy, neuropathic pain of other causes, epilepsy, etc. Some of its most common side effects include the following: ataxia, nystagmus, drowsiness, headaches, diplopia, fatigue and myoclonic twitches.1 All of these effects appear quite often in patients with chronic kidney disease, especially if they are undergoing dialysis and their doses are not adjusted to their glomerular filtration rates.2 We describe a new case of rhabdomyolysis and acute renal failure due to gabapentin in order to raise awareness of the importance of monitoring creatine kinase (Ck) and renal function, and of being on the alert for side effects every time this drug is used.1,3 The patient, aged 49 years, was taken to the Emergency Department due to delirium, deteriorating condition and myalgias evolving over 48 hours. The patient had visited the Emergency Department two days before due to lumbosacral pain, was diagnosed with mechanical low back pain, and began treatment with 600mg gabapentin every 8 hours. Relevant me Continue reading >>

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  1. Prairie-dawg

    So I went to the pharmacy yesterday to pick up a new scale and some Ketostix. The pharmacist (who works right next door to me and I've become friendly with) asked me if I was "starting some kind of crazy diet." I told him I've started a ketogenic diet and I'm just trying it out to see if it's right for me. He asked me a few questions about it, mostly about macro ratios and if it's been working so far. When I told him about the higher fat ratio (as opposed to high protein) he seemed somewhat intrigued, but still a little skeptical. The other pharmacist who was working with him chimed in at that point. He said apparently in some Scandinavian countries, they've found that a higher fat content and fewer simple carbs in a person's diet is ideal and actually recommended. However, they both agreed that ketosis for an extended period of time can be very hard on the kidneys. I did a little investigating on my own and there's very little info regarding the long-term effects of the high fat/moderate protein/low carb keto diet. So my question is, has anybody experienced any kidney issues on this diet? Has anyone received any similar warnings from their physician?
    TL;DR
    Pharmacist warned about kidney issues caused by long term ketosis. Seeking out facts/sources to prove or disprove this claim.

  2. cloudmind

    When I first started keto I ended up going to hospital because I had severe internal pain that wouldn't go away. Turns out I was eating far too much protein so my kidneys were giving me grief. Fixed it by upping the fat macros in my diet and I went back to being pain free. Hooray for butter and coconut oil!
    Given my experience, I can understand where the pharmacists are coming from since I think there might* have been a spate of people doing atkins-like diets with kidney problems in the past (too much protein, not enough fat).
    *rampant speculation on my part

  3. Prairie-dawg

    I don't blame them for that at all. In fact, before I really started doing my homework on keto, I used to internally roll my eyes when people would talk about low carb dieting. I think there's a lot of risidual negativity held over from the early days of Atkins regarding low carb diets. Fortunately, I'm always happy to have a teaching moment when the chance arises!

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Invokana Kidney Failure Lawsuit

**Blog shared with us by attorney Stuart Scott at Spangenberg Law Firm** Invokana Lawsuit: Investigation of Kidney Failure, Ketoacidosis and Other Injuries Linked to Type 2 Diabetes Medicines Invokana and Invokamet The attorneys at the Spangenberg Law Firm are investigating the link between several type 2 diabetes medicines and serious injuries – including kidney failure and ketoacidosis – suffered by patients after taking them, including: Invokana (canagliflozin) Invokamet (canagliflozin/metformin) Jardiance (empagliflozin) Xigduo XR (dapagliflozin/metformin) Farxiga (dapagliflozin) Glyxambi (empagliflozin/linagliptin) The FDA has warned in a drug safety announcement that these drugs may cause a serious health condition known as ketoacidosis. Ketoacidosis (also known as acidosis or diabetic ketoacidosis (DKA) – causes the body to produce excessive levels of blood acids and may cause diabetic comas or death. In addition to causing an increased risk of ketoacidosis, Invokana, Invokamet, and SGLT2 inhibitors have been linked to incidents of other side effects including kidney damage and ketoacidosis. The FDA, in its announcement, warned patients that they should seek immediate Continue reading >>

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  1. bbearsmama

    Ketones found in urine-is our diet bad for our kidneys?

    Hi there-
    I went to see my PCP for a urinary tract infection today and she said there was a lot of stuff in my urine-ketones, blood (which is always there-which is why I also see a nephrologist), and some protein. She thinks the ketones are because of my high protein diet and she told me to try to eat a more balanced diet (more carbs, fruits, veggies). How is this possible with such a tiny pouch? Has this happened to anyone else and if so-what did you do? Is it dangerous to have ketones in your urine? I do worry about my kidney function. My nephrologist likes to do labwork (blood/urine) every 6 months to keep an eye on things. He doesn't think my labs have warranted doing a kidney biopsy at this point. The last time I saw the nephrologist was before my RNY. I just don't want my diet to be damaging to my kidneys.
    Has this happened to anyone--kidney damage as a result of the post-op diet? I know that it will be easier to eat a more balanced diet as a I get further out, right?
    Thank you all for your advice and help!
    Sincerely,
    Pam

  2. RainbowRN

    I know that when the atkins diet was really popular, more people started talking about ketones in the urine. The big deal about it is that protein molecules are actually really big and more difficult for the kidneys to filter. Therefore the kidneys can be damaged overtime. Now, I'm not sure about how long it takes or how much protein it would take to do that. All I know is that, last year before I even considered WLS, my NUT put me on a protein sparing modified fast. It was a diet that was primarily protein only. It was very high amounts of protein. Greater than 140mg a day. I was told that I would do the diet for 3 months and then I had to go off of it for 3 months and then back on for three months simply because of the risk of damage to my kidneys. I don't consume that much protein since surgery. I try to make sure I get in 60mg a day. I would be curious to find out if kidney damage is a possibilty for us. In all my research I have not heard of that being a side effect.

  3. bbearsmama

    Before I had my surgery, I did talk to my nephrologist about the high protein diet and he thought it would be fine. He said that 60 g. of protein is really not that much. What is considered the "normal" intake of protein (for people who haven't had wls)? I think it's around 50 g. of protein. I'm not sure, though. And the reality is-I struggle to get 60 g. in per day. Most days I don't even get there-it's more like 50 or 55 g.
    That is interesting about the protein molecules being big.
    Thank you so much for your reply!
    Pam :)

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