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Dka Treatment Guidelines 2015

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Diabetic Ketoacidosis In Children And Adolescents Raghupathy P - Indian J Endocr Metab

Diabetic ketoacidosis (DKA) is considered to be a common presentation of type 1 diabetes mellitus (T1DM) and occasionally, type 2 diabetes mellitus (T2DM) in children and adolescents. DKA arises due to lack of adequate insulin in the body. Insulin stops the use of fat as an energy source by inhibiting the peptide hormone glucagon. Without insulin, glucagon levels rise resulting in the release of free fatty acids from adipose tissue, as well as amino acids from muscle cells. The biochemical criteria for DKA diagnosis include hyperglycemia (blood glucose [BG] higher than 11 mmol/L or 200 mg/dL) with a venous pH of <7.3 and/or a bicarbonate (HCO 3 ) level of <15 mmol/L; ketonemia and ketonuria. Although not universally available, blood -hydroxybutyrate concentration should be measured whenever possible, and a level of 3 mmol/L is indicative of DKA. Urine ketones, of moderate or large size (typically 2+), are also indicative of DKA. The clinical signs of DKA include dehydration (may be difficult to detect), tachycardia, tachypnoea (may be mistaken for pneumonia or asthma), deep sighing (Kussmaul) respiration with a typical smell of ketones in the breath (variously described as the odo Continue reading >>

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Popular Questions

  1. inmalafide

    The Keto folks say that once your body goes into keto, no matter how much you eat, your body will continue cannibalizing fat. But I find this hard to be true. What if i am on a giant calorific surplus and still in keto? what happens?
    As there is no insulin spike, the extra calories dont go to the muscles either right?
    (Sleep hacker trying to see the effect of keto diet on my sleep, please comment only if you know what ketosis is and/or have tried it out)

  2. Jason Hooper

    Lipolysis is more likely to occur when more fat is consumed. There is much lower biological energy expended when fats are metabolized in the gut rather than mobilizing lipase in the various adipose tissues. Transport is not governed by insulin; rather, the sympathetic nervous system--hence your sleep issues. Insulin regulates lipogenisis through the genetic signaling of malic enzymes.

  3. Dan O.

    I have been on a 100% keto diet for a few years now. Before that low carb Paleo. Before that paleo with refeeds and leangains.
    I still IF and eat epi-Paleo. Yes I can over eat and gain weight in this diet.
    Sleep - I sleep great or best on a light to empty stomach. 2 -4 hours after eating a normal sized satisfying meal.
    If I eat a heavy full meal right before bed my sleep quality goes down and I don't feel as good when I wake up.
    I usually wake up with lots of energy and no hunger.

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National Paediatric Diabetes Audit National Conference 2017 (13th January 2017)

Management Of Paediatric Diabetic Ketoacidosis: An Audit

Introduction: NICE Guidelines NG18 (published 2015) advocate a more conservative approach to management of diabetic ketoacidosis (DKA) in children and young people up to the age of 18, in an attempt to reduce the risk of cerebral oedema. We aimed to assess if management of DKA in children at Manor Hospital was compliant with hospital guidelines, that were based on BSPED guidelines (issued 2009). We analysed the difference in total fluid administered if the new DKA guidelines were in place, specifically in the case of young people. Method: We retrospectively audited case notes of all patients up to the age of 19 years admitted to Walsall Manor Hospital with DKA between 1st July 2014–31st July 2015 (n=13). A standardised proforma was used to collect data, which was then analysed. Results: Current hospital policy advocates that young people after their 16th birthday are managed by the adult medical team. The adult DKA Guideline is based on recommendations of Joint British Diabetes Societies Inpatient Care Group recommendations (2013). The age range was 10 to 18 years. Ten patients were treated using the paediatric and three were treated using the adult guidelines. There was one sign Continue reading >>

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  1. toothhornet88

    ">
    I thought that the more Donating groups you have the more stable the molecule is===> less acidic! and In my opinion I think that Anhydride>Formaldehyde>Aldehyde>Ketone
    Also pKa of Formaldehyde is 13.3
    pKa of aldehyde is 17
    pKa of ketone is 20
    So why is the answer A, I don't get it!

  2. flin5845

    toothhornet88 said: ↑
    ">
    I thought that the more Donating groups you have the more stable the molecule is===> less acidic! and In my opinion I think that Anhydride>Formaldehyde>Aldehyde>Ketone
    Also pKa of Formaldehyde is 13.3
    pKa of aldehyde is 17
    pKa of ketone is 20
    So why is the answer A, I don't get it!
    Click to expand... The carbons on a ketone or aldehyde can backdonate through hyperconjugation stabilizing the cation

  3. wizi

    For II and IV: Just by looking at it you can tell II is the most acidic one, and IV is the least acidic.
    C A R DI O. We use R which is Resonance -> II: most acidic and IV: least acidic.
    For I and III: just like you said, ketone's pKa > aldehyde's pKa -> aldehyde is more acidic.

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What is KETOACIDOSIS? What does KETOACIDOSIS mean? KETOACIDOSIS meaning - KETOACIDOSIS definition - KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids. The two common ketones produced in humans are acetoacetic acid and ß-hydroxybutyrate. Ketoacidosis is a pathological metabolic state marked by extreme and uncontrolled ketosis. In ketoacidosis, the body fails to adequately regulate ketone production causing such a severe accumulation of keto acids that the pH of the blood is substantially decreased. In extreme cases ketoacidosis can be fatal. Ketoacidosis is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Prolonged alcoholism may lead to alcoholic ketoacidosis. Ketoacidosis can be smelled on a person's breath. This is due to acetone, a direct by-product of the sp

Clinical Management Of Diabetic Ketoacidosis

Abstract: Background: Diabetic ketoacidosis (DKA) is a medical emergency where rapid and effective management is necessary to aid prompt recovery and to prevent life threatening complications such as: cerebral oedema, hypokalaemia, hypo/hyper-glycaemia and hypovolaemia. It requires effective co-operation between the emergency department (ED), general medical team and endocrinology team members. Within the past 4 years, a new national guideline regarding the management of DKA has been used by the majority of hospitals in the United Kingdom (1). One of many points in these guidelines is that a fixed rate of iv insulin infusion with appropriate rate of iv fluids (normal saline and 10% of glucose) is preferable to variable insulin infusion. The new guidelines describe clearly each step of DKA management. This audit investigated the management of DKA at Medway Hospital to see if national and local hospital guidelines were being adhered to. Aims and Objectives: Multiple steps of clinical management of DKA were examined, including: recognition of DKA, initiation of treatment, the occurrence of hypoglycaemia and hypokalaemia, blood glucose and ketones monitoring, venous blood gases monitor Continue reading >>

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Popular Questions

  1. Im_In_College

    I was thinking of incorporating a 36 hour carb-up/low fat period every week. First carb meal would be friday night, eat carbs and low fat throughout saturday, back on Keto for sunday brunch, then excersize sunday afternoon, and hopefully I'll be back in Keto mid-day monday. Any thoughts? Has anyone done this?
    EDIT: Right now I'm primarily weight loss, with light weight training 2-3 times/week

  2. nothingtoseehere28

    if your goal is to lose fat, carb ups are unnecisary and counter productive.

  3. ElmStreetsLoverBoy

    What this guy said.
    If you've still got significant weight to lose, this may not be the route you want to go. I'd only consider this if you start training more than 3 times a week or your training is more intense than "light weight" training.

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