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Difference Between Ketosis And Ketoacidosis

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Understanding Ketosis Vs Ketoacidosis

written by: Ravneet Kaur edited by: Diana Cooper updated: 1/28/2011 Although you might think of ketosis and ketoacidosis as the same, they are two different conditions. Read on to learn more about these terms mean and the relationship between ketosis vs ketoacidosis. Some people believe that ketosis and ketoacidosis are the same condition, but these are two different conditions related to the body's metabolism. Learning the differences between ketosis vs ketoacidosis will help to dispel myths surrounding their cause and diagnosis. Ketosis is a state in which the body starts burning fat for energy due to lack of new glucose in the diet. Althugh ketosis is commonly seen in individuals participating in a low-carb diet, it is also seen in people suffering from a lack of insulin as well as prolonged periods of fasting or starvation. Carbohydrates provide the body with glucose. The pancreas secretes a hormone called insulin that works with the glucose in the bloodstream to provide energy to the body's organs and cells. When the glucose supply is exhausted, it begins to break down stored fat to meet its energy needs for normal functioning. The accumulation of ketone molecules in the bloo Continue reading >>

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  1. purplegolfball

    Intermediate Fasting and Maintaining Ketosis

    I ran across an interesting post and response over on Peter Attia's blog:
    "lorraine July 22, 2012
    Doc, not sure where to ask this, but this seems as good a place as any. I read somewhere along the way that you’ve done some self-experimentation with IF. I’ve been doing the same, but limited to eating “within a window”. I usually wait 16-17 hours after last meal to start the new day’s eating. and eat two meals within that 7 or 8 hours. I really like eating this way, but I have found that it kicks me out of ketosis. Not so if I do fasted exercise. It seems to me, theoretically anyway, that if I’m running on ketones I shouldn’t have to turn on too much gluconeogenesis, but it doesn’t appear to be working out that way. I get kicked out of ketosis especially in the morning of the fast. Have you experienced anything like this? At least with me, it seems I need to pick one or the other. Thanks for any input.
    Peter Attia July 22, 2012
    You’re spot on. IF makes a steady-state of ketosis almost impossible, because of the bolus of protein in one meal. I’ll detail all of this when I get the post (or short series, more likely) on this topic."
    Lately, I've been eating one large meal with some snacking or a second light meal per day. I've found I like this. Keeping a ketonic ratio around two, it does result in an intake of protein for me up to around 60-70 grams at one time.
    I haven't noticed high post prandial readings or any significant increase in my morning fasting readings. This leads me to believe I'm maintaining ketosis, but I'm not sure. I guess it boils down to does it simply take maintaining a ketonic ratio to maintain a state of ketosis, or does it also require limiting a maximum protein intake at one time? What exactly, if anything, does our glucose readings say about maintaining ketosis?
    Curious as to what some of you longer term ketogenics have run across. I hate to break down and buy those expensive ketone meter strips, but maybe thats the only way to know for sure.

  2. jim55

    Today begins my third week of if. I haven't had any problem staying in keto when i break a fast. I've done two 41 hour fasts with the other 10 days being 20 hour fasts. I like the 20 hour fasts. It's just like normal eating without breakfast really. Very easy for me to create a caloric deficit without any feelings of depervation. My workouts have been fantastic, i have so much more energy it seems. I read somewhere that the gut has a hormone or something called gerlin (spelling) that causes hunger and fasting over time will silence this. I think it's true as i just don't have big hunger. I don't think it would be as easy if i were not keto addapted. My weight is down somewhere between four and six pounds. Hard to determine exactly as the fasting does cause rather large hydro swings.

  3. blaisjp

    Well this is all very interesting reading. Really. I mean it. I do 24 hour fasts a couple times a month. I find it is most effective combined with a high intensity workout of some kind. I don't really fall out of ketosis, at least not when I check, I just notice that my blood sugar goes up during the fast and exercise and then drops for the the next several days. I presume because glycogen is depleted and needs to rebuild. I know this goes goes against the idea that ketosis only happens when glycogen is depleted i just don't experience this.

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

What’s The Difference Between Ketosis And Diabetic Ketoacidosis?

Ketosis and ketoacidosis sound similar and are sometimes confused, but don’t mistake these conditions for one another. These involve two different sets of circumstances with considerably different outlooks. Both are triggered by an increase of ketones in the body, which are acids released into the bloodstream when the body burns fat for energy instead of carbohydrates. But it’s how the body responds to this increase that sets ketosis and ketoacidosis apart from each other. RELATED: How to Tell the Difference Between Good and Bad Carbs What Is Ketosis and How Does the Process Work? “Ketosis is a natural state that occurs when you start to metabolize fat instead of sugar,” says Michael Greenfield, MD, endocrinologist and chief medical officer at El Camino Hospital in Palo Alto, California. “It occurs often when people fast and use up the stores of sugar in their body." To understand ketosis, it helps to understand how the body burns energy. Carbohydrates and fat are both energy sources, and the body typically burns carbs (sugar or glucose) first, and then fat. If there aren’t enough carbohydrates in your system, it begins to break down fat for energy, which puts your body Continue reading >>

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  1. jodysd6

    What is DKA?

    What is DKA?
    DKA stands for Diabetic Ketoacidosis, and it is a potentially life threatening complication of Diabetes. It is usually associated with uncontrolled high blood glucose levels and it occurs as a result of insufficient insulin.
    Who is at risk for DKA?
    Type 1 diabetics are most at risk of developing DKA as they have no residual insulin production, often even a little insulin production is enough to prevent DKA developing. Some Type 2 Diabetics who also have no residual insulin production are also at risk.
    Many Diabetics will never experience DKA, and many cases of DKA occur in people who have previously been undiagnosed with diabetes. In people who know they are Diabetic there are a few potential triggers for DKA:
    · Inadequate Insulin – insulin being missed, failed delivery from a pump or much more rarely ‘bad’ insulin
    · Infection – particularly bacterial infections, and especially if the patient is unwell and unable to test and adjust insulin as usual
    · Other Illness – anything which stresses the body, such as a heart attack
    Most Episodes of DKA in known diabetics can be prevented if you know the symptoms, know how to manage when you are unwell and are able to make contact with your healthcare team early. It is estimated that around 25% of admissions for DKA in known diabetics occur when people stop insulin because they are not eating or are vomiting. It is very important to keep taking insulin even when you are ill, at these times you may even need more than usual despite not eating.
    What happens in DKA?
    Without Insulin all the glucose in your blood is unable to get into the cells where it is needed for fuel. Your blood glucose level will rise, and your liver will produce even more glucose because it senses that your cells are ‘starving’. 2 Parallel processes then occur which together lead to dehydration and a lowering of the bloods pH level – your blood becomes acidic.
    As the blood glucose rises your kidneys attempt to get rid of all the excess glucose, as excess glucose is ‘spilled’ into the urine water follows it, this is what makes you go to the toilet more frequently. As you lose water you feel thirsty, and develop a dry mouth.
    Because the cells cannot use the glucose in your blood (because the cells require insulin to let the glucose in) they need to find another source of energy. The cells can get the energy from other sources such as fat but in doing so they produce ketones. Ketones are acidic and as they build up in your blood they lower the pH of your blood. This is dangerous because all the cells in your body rely on the pH of your blood staying within a certain range. As the pH of your blood drops you may notice you are breathing faster than usual, this is your bodies way of attempting to raise your bloods pH level.
    By this stage most people will be feeling very unwell and will seek help, however if this process continues it can be life threatening, as your brain cannot survive indefinitely without glucose and other cells in your body begin to die due to the acidity of the blood. This is why it is so important to seek help early.
    What are the symptoms of DKA?
    Early Symptoms
    · Frequent Urination
    · Thirst
    · Dry Mouth
    · Nausea
    Later Symptoms
    · Vomiting
    · Abdominal Pain
    · Rapid Breathing
    · Confusion
    · Drowsiness
    · Coma
    Some people are able to taste ketones on their breath, this has been described as tasting how you expect nail varnish remover to taste! Friends or family may also be able to smell ketones on your breath (often described as sweet smelling or smelling of ‘pear drops’)
    How can I prevent DKA?
    Sometimes nothing you can do will stop it, and you will have to go to the ER in order to recieve appropriate treatment, however you may be ableto prevent DKA if you know the warning signs and respond quickly. If you have a high blood glucose you need to take an appropriate correction shot of fast acting insulin ( your doc can help you work out how much you need to take). Once you have taken the correction, you need to keep a close eye on your BG levels as they are falling, and be on the look out for hypoglycaemia. It is also importand to drink plenty of clear fluids, ideally water, as this will help combat any dehydration and help your body flush out the excess glucose and any ketones. If your blood glucose levels are falling steadily and you feel well, these steps may be all that is needed. You should continue to keep a close eye on you BG levels and on any ketones though, and be prepared to take further action if things stop improving or worsen.
    When Should I go to the ER?
    · If your BG is above 400mg/dl (or 20mmol/l) for more than a short period of time (some people may develop DKA at lower levels, so be prepared to seek help if you have any other symptoms, even if your BG is lower than this)
    · If your BG does not come down rapidly with short acting Insulin
    · If you have High Levels of Ketones (you can test for ketones using urine strips which are readily available, or some brands of glucose meter will allow you to test for blood ketones)
    · If you cannot tolerate oral fluids or begin vomitting
    · IF YOU ARE EVER IN DOUBT GO TO THE ER
    Remember it never hurts to call your healthcare team if you are at all concerned, they can advise you and would much rather you call them early than you end up more ill.
    What will happen in the ER?
    When you arrive at the ER you should tell them straight away that you suspect you may be in DKA. Sometimes if you have recently taken insulin your BG may appear normal and they may not realise what has been going on.
    Exactly what happens in the ER depends on how advanced the DKA is when you arrive, however there are certain things which are standard practice in the management of DKA. This includes:
    · Checking your pulse, blood pressure, temperature and respiratory rate – you can develop a low blood pressure due to the dehydration, and your respiratory rate may be raised by your body trying to correct the acidosis. If your temperature is raised it may be a sign that you have an infection.
    · Taking a blood sample from a vein – this allows the doctors to confirm your blood glucose, and to check the levels of other salts in your body. They will also check to see if you have any signs of infection, and they may take a sample to send to the lab to see if there is any bacteria in the blood. In some hospitals they will use this sample to check the pH of the blood too, but in some hospitals they may use a blood sample from the artery in your wrist. This test can be quite painful but it gives the doctors lots of useful information on the acidity of your blood, and allows them to confirm the diagnosis of DKA.
    · Start an IV – as you will probably be dehydrated the most important thing is to replace the lost fluid and this is usually done using an IV. An IV is usually also needed to give you insulin.
    · Most hospitals will also perform an ECG, an electrical tracing of your heart to check that you are not having any problems with your heart, this is a painless test and is routine for DKA.
    · They may also order a chest x-ray and take a sample of your urine, they do this because they are looking for any infection, and chest infections and urine infections are the most common.
    Most of the time you will be admitted to the hospital for a couple of days so they can ensure everything is back to normal, and they can restart your usual insulin. Once you are eating and drinking normally and your blood sugars are stable you should be able to go home. If they have found a reason for the DKA such as an infection you may have to stay longer, or take medication such as antibiotics when you go home.
    After an episode of DKA
    There is usually no lasting effects after an episode of DKA, though you may feel tired and not quite yourself for a while once you get home. You may need to rest a bit more at home in the first few days. You should keep a close eye on your blood sugars, and be prepared to contact your healthcare team if you are not happy with your results. You may have been given a follow up appointment with an endocrinologist or diabetes specialist nurse to discuss how things are going since you got home, you should take along any records of your blood sugars and feel free to ask about any concerns you have had. If you have had something like an infection your blood sugars may still be running higher than usual and you will have to discuss whether you need to increase your insulin.

  2. whisperwillow

    This is a great post. Thanks for posting it. It might save a life or two. I went to the ER with a BG of 986. I didn't know I had diabetes. I don't know how I wasn't in a coma. The docs couldn't either. But I am living testament that it is serious and it can kill you if left untreated. If you are experiencing any of this symptoms, don't walk but run to the ER. (Figuratively speaking). Your life might be on depend on it.

  3. hannahtan

    I'm a living testament as well that ketones in T2 happens...even with just a level of 20.9mmol/l (376 mg/dl)...and i was lucky to caught it early...
    Thanks Jody for the GREAT post on DKA...this will definitely be handy to save a life or two...

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Which is the best weight loss diet? Ketogenic diet vs low carb diet vs atkins vs paleo? Which one of these meal plans is best to burn fat? FREE 6 Week Challenge: https://gravitychallenges.com/home65d... Fat Loss Calculator: http://bit.ly/2O70G4m Isn't the ketogenic diet and low carb diet essentially the same thing? How about Atkins and paleo aren't all of these diets just a fancy way of saying keep your carbs low. Well it's definitely safe to say that you are limiting your carb intake in all of these diet plans but each plan calls for a slightly different approach to burning fat. Most ketogenic diets require you to keep your carbs under 30 grams a day and the most carbs that I've ever seen on a keto plan was 50 grams a day. Usually this will account for 5% of your total daily intake. Then you would have somewhere between 75 to 80 percent of your calories from fat. And finally 15 to 20 percent of your calories from protein. With ketogenic it's clear that the carbs are very limited at only 5 percent per day and the reason why carbs are so limited is because the ketogenic diet is trying to put you into ketosis. To sum it up simply ketosis is a state in which you're going to burn more

Ketoacidosis During A Low-carbohydrate Diet

To the Editor: It is believed that low-carbohydrate diets work best in reducing weight when producing ketosis.1 We report on a 51-year-old white woman who does not have diabetes but had ketoacidosis while consuming a “no-carbohydrate” diet. There was no family history of diabetes, and she was not currently taking any medications. While adhering to a regimen of carbohydrate restriction, she reached a stable weight of 59.1 kg, a decrease from 72.7 kg. After several months of stable weight, she was admitted to the hospital four times with vomiting but without abdominal pain. On each occasion, she reported no alcohol use. Her body-mass index (the weight in kilograms divided by the square of the height in meters) was 26.7 before the weight loss and 21.7 afterward. Laboratory evaluation showed anion-gap acidosis, ketonuria, and elevated plasma glucose concentrations on three of the four occasions (Table 1). She had normal concentrations of plasma lactate and glycosylated hemoglobin. Screening for drugs, including ethyl alcohol and ethylene glycol, was negative. Abdominal ultrasonography showed hepatic steatosis. On each occasion, the patient recovered after administration of intraven Continue reading >>

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  1. spoiltmomof2

    For me it doesn't So by eating high fat if I eat until I'm full I lose weight very, very, very slowly because I'm taking in too many calories I'm assuming.
    I know everyone says Atkins needs to be high fat but why?
    Even if I stay below 20 grams of carbs a day I don't lose weight unless I stay below 1600 calories.
    Staying low Carb does control my blood sugar and my Carb/sugar cravings so I don't want to stop but I do need to keep losing. right now I can't get below 175

  2. ouizoid

    see, I think we are all different. I need to eat very low fat with slightly higher carbs to feel appetite control. When I eat high fat low carb, I get hungry, almost bingey. If I eat a more vegetable based diet, I am free of cravings and hunger. I just think we all have different genetic organizations. I am definitely in favour of lowish carb--but I had to find my way of having appetite suppression, and it is not the same as others.

  3. Ntombi

    Ketosis definitely suppresses my appetite. What's more, not eating carby food doesn't lead to blood sugar highs and lows, so I don't feel starving three hours after eating something like oatmeal. So the combination of eating very low carb and being in ketosis makes a difference for my hunger pattern.
    I eat very low carb (fewer than 20g total), moderate protein (~120g--enough to nourish my LBM), and enough fat to make up the rest of my calories, because fat is the macronutrient that won't affect blood sugar nor be stored as fat. So yes I eat high fat, but that doesn't mean that I'm eating a ton of calories. I don't count calories, but I generally average about 1800-2000 calories per day, with some outliers.
    If you need to keep your calories below 1600, do that.

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