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A Pediatric Suicide Attempt By Ingestion Of Metformin, Glimepiride Andsulpiride: A Case Report And Literature Review
Received date: March 01, 2016; Accepted date: July 04, 2016; Published date: July 11, 2016 Citation: Tarek G, Kais G, Ramzi G (2016) A Pediatric Suicide Attempt by Ingestion of Metformin, Glimepiride and Sulpiride: A Case Report and Literature Review. J Clin Toxicol 6:310. doi:10.4172/2161-0495.1000310 Copyright: 2016 Tarek G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. A case of a pediatric patient poisoning after ingestion of metformin , glimepiride and sulpiride, he was presented to the emergency service with symptoms and signs of hypoglycemia. Using a risk assessment based approach, the management of glimepiride and metformin overdose is discussed. Glimepiride overdose invariably results in profound hypoglycemia that requires resuscitation with IV dextrose and the use of octreotide as an antidote. Metformin overdose rarely causes problems. The acute sulpiride poisoning is poorly reported in the medical literature. Pediatric; Suicide attempt; Poisoning; Metformin; Glimepiride; Sulpi
Metformin Side Effects: Side Effects of Metformin: Metformin and Diabetes
Side Effects Of Metformin Are More Serious Than You Think
The Side Effects of Metformin can range from not so serious, to deadly, are the risks of Metformin and Glucophage side effects worth it? This page will give you information that might be able to help you decide that for yourself. Also known as Glucophage, this is an antidiabetic medicine most often used in those with Type 2 Diabetes who are also overweight. It’s also used extensively in women with Polycystic Ovarian Syndrome, a condition known as PCOS, which is often accompanied by higher blood sugar readings which often benefit from the blood sugar lowering effects of Metformin. While at first glance it seems that Side Effects of Metformin are rare, a closer look and a little math show that there are some serious problems that can occur when taking this drug, and others that can and should be prevented easily, but are usually not due to a medical community that simply does not use nutritional supplements in the prevention of even well-known, easily preventable Glucophage side effects. Vitamin B12 Deficiency Vitamin B12 and Folic Acid Deficiency are well-known and well-studied side effects of Metformin. Despite the fact that there have been many studies confirming this problem ov
What is MATERNAL DEATH? What does MATERNAL DEATH mean? MATERNAL DEATH meaning - MATERNAL DEATH definition - MATERNAL DEATH explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Maternal death is defined by the World Health Organization (WHO) as "the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes." The world mortality rate has declined 45% since 1990, but still every day 800 women die from pregnancy or childbirth related causes. According to the United Nations Population Fund (UNFPA) this is equivalent to "about one woman every two minutes and for every woman who dies, 20 or 30 encounter complications with serious or long-lasting consequences. Most of these deaths and injuries are entirely preventable." UNFPA estimated that 289,000 women died of pregnancy or childbirth related causes in 2013. These causes range from severe bleeding to obstructed labour, all of which have highly effective interventions. As women have gained access to family planning and skilled birth attendance with backup emergency obstetric care, the global maternal mortality ratio has fallen from 380 maternal deaths per 100,000 live births in 1990 to 210 deaths per 100,000 live births in 2013, and many countries halved their maternal death rates in the last 10 years. Worldwide mortality rates have been decreasing in modern age. High rates still exist, particularly in impoverished communities with over 85% living in Africa and Southern Asia. The effect of a mother's death results in vulnerable families and their infants, if they survive childbirth, are more likely to die before reaching their second birthday. Factors that increase maternal death can be direct or indirect. Generally, there is a distinction between a direct maternal death that is the result of a complication of the pregnancy, delivery, or management of the two, and an indirect maternal death. that is a pregnancy-related death in a patient with a preexisting or newly developed health problem unrelated to pregnancy. Fatalities during but unrelated to a pregnancy are termed accidental, incidental, or nonobstetrical maternal deaths. The most common causes are postpartum bleeding (15%), complications from unsafe abortion (15%), hypertensive disorders of pregnancy (10%), postpartum infections (8%), and obstructed labour (6%). Other causes include blood clots (3%) and pre-existing conditions (28%). Indirect causes are malaria, anaemia, HIV/AIDS, and cardiovascular disease, all of which may complicate pregnancy or be aggravated by it. Sociodemographic factors such as age, access to resources and income level are significant indicators of maternal outcomes. Young mothers face higher risks of complications and death during pregnancy than older mothers, especially adolescents aged 15 years or younger. Adolescents have higher risks for postpartum hemorrhage, puerperal endometritis, operative vaginal delivery, episiotomy, low birth weight, preterm delivery, and small-for-gestational-age infants, all of which can lead to maternal death. Structural support and family support influences maternal outcomes. Furthermore, social disadvantage and social isolation adversely affects maternal health which can lead to increases in maternal death. Additionally, lack of access to skilled medical care during childbirth, the travel distance to the nearest clinic to receive proper care, number of prior births, barriers to accessing prenatal medical care and poor infrastructure all increase maternal deaths. Unsafe abortion is another major cause of maternal death. According to the World Health Organization, every eight minutes a woman dies from complications arising from unsafe abortions. Complications include hemorrhage, infection, sepsis and genital trauma. Globally, preventable deaths from improperly performed procedures constitute 13% of maternal mortality, and 25% or more in some countries where maternal mortality from other causes is relatively low, making unsafe abortion the leading single cause of maternal mortality worldwide.
Common Diabetes Drugs Associated With Increased Risk Of Death
Follow all of ScienceDaily's latest research news and top science headlines ! Common diabetes drugs associated with increased risk of death Compared to another popular drug, three widely used diabetes medications are associated with a greater risk of death, a large new analysis finds. Compared to another popular drug, three widely used diabetes medications are associated with a greater risk of death, a large new analysis finds. The results were presented June 25 at The Endocrine Society's 94th Annual Meeting in Houston. The drugs, glipizide, glyburide, and glimepiride, are known as sulfonylureas, which help decrease blood-sugar levels among type 2 diabetes patients by stimulating the pancreas to produce insulin. In the past, these medications were considered comparable to one another in terms of effectiveness and safety. Recently, however, research has shown some sulfonylureas may be safer than others. These findings led to this latest research, which compared them to another type of blood-sugar-reducing drug known as metformin. All four medications are available under low-cost, generic labels. "We have clearly demonstrated that metformin is associated with a substantial reduction
The preliminary findings of a study from Denmark suggest that children and young adults with diabetes may have seven times the risk of sudden cardiac death of young people without it. The study — led by researchers at Copenhagen University Hospital in Denmark — was presented at the American Heart Association's Scientific Sessions 2017, held this week in Anaheim, CA. Its findings also revealed that children and young adults with diabetes may h ...
Tweet After diabetes diagnosis, many type 1 and type 2 diabetics worry about their life expectancy. Death is never a pleasant subject but it's human nature to want to know 'how long can I expect to live'. There is no hard and fast answer to the question of ‘how long can I expect to live’ as a number of factors influence one’s life expectancy. How soon diabetes was diagnosed, the progress of diabetic complications and whether one has other e ...
Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. Well let's just say I was prepared for the stomach problems as most of you have talked about. However it has been absolutely horrid! I started my 2000mg of metformin yesterday, 1000 in the am and the rest at dinner. All I can say is oh my god! To think I felt sick befo ...
A 2015 study compiled by the U.S. Department of Health and Human Services in partnership with the Centers for Disease Control and Prevention and the National Center for Health Statistics found that there were around 2.6 million deaths registered in 2014. In their research, these organizations examined the leading causes for fatalities and found the top 10. Let’s take a closer look: Heart disease Heart disease is the No. 1 killer of both men and ...
Complications caused by diabetes People with diabetes must routinely monitor and regulate their blood sugar. No matter how careful you may be, there’s still a possibility that a problem might arise. There are two types of complications you may experience: acute and chronic. Acute complications require emergency care. Examples include hypoglycemia and ketoacidosis. If left untreated, these conditions can cause: seizures loss of consciousness dea ...
Severe hypoglycemia, or diabetic shock, is a serious health risk for anyone with diabetes. Also called insulin reaction, as a consequence of too much insulin, it can occur anytime there is an imbalance between the insulin in your system, the amount of food you eat, or your level of physical activity. It can even happen while you are doing all you think you can do to manage your diabetes. The symptoms of diabetic shock may seem mild at first. But ...