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Can Metabolic Acidosis Be Caused By Seizures?

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Severe Diabetic Ketoacidosis Complicated By Hypocapnic Seizure

Summary In clinical practice, seizures independent of hypoglycemia are observed in patients with type 1 diabetes mellitus (T1DM) more frequently than expected by chance, suggesting a link. However, seizures during management of diabetic ketoacidosis (DKA) have generally been considered a bad prognostic factor, and usually associated with well-known biochemical or neurological complications. We present the case of a 17-year-old girl with known T1DM managed for severe DKA complicated by hypocapnic seizure. We review the literature on this rare occurrence as well as outline other possible differentials to consider when faced with the alarming combination of DKA and seizure. Learning points: Seizures during DKA treatment require immediate management as well as evaluation to determine their underlying cause. Their etiology is varied, but a lowered seizure threshold, electrolyte disturbances and serious neurological complications of DKA such as cerebral edema must all be considered. Sudden severe hypocapnia may represent a rare contributor to seizure during the treatment of DKA. Background Diabetic ketoacidosis (DKA) is an endocrine emergency occurring in patients with both new-onset and Continue reading >>

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Popular Questions

  1. noexcuses84

    hi everyone i need some help. Today i had my monthly check up with my diabetes nurse and she found a high level of ketones in my urine. It's the first time i've ever tested positive for them and am now being monitored over the next couple of weeks to c if they leave my system. Has anyone else had this problem and if so what did u do to get rid of them?? I absolutely don't want to end up with Ketoacidosis so i need as many ideas as possible. My diary is open to anyone that is willing to also have a look n c if i need to adjust anything. i increased my calories to from 1310 as i was told that maybe i'm not eating enough?! so confused about this one!

  2. concordancia

    You aren't tracking protein, but ketones are just the by product of protein metabolism. Did your doctor mention them actually being a problem? Their may be some concern with them indicating other problems related to your diabetes, but ketones are usually only an issue for people with kidney problems.
    As a matter of fact, low carb diets all lead to ketone production, so the only way to address them is eat less protein and more carbs, which doesn't sound like very good advice for a diabetic.

  3. noexcuses84

    thanks heaps, yeah she said that ketones in a diabetic is not good but didn't explain it further. i have to eat a certain amount of carbs each day which i am doing, so i will monitor my protein from now on. thank you

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