Using A Ketogenic Diet To Stop Brain Tumor Growth
Pablo received devastating news at age 25: He had a terminal brain tumor and only between 6 and 9 months to live. Doctors suggested chemotherapy – despite no hope of a cure in his case. After studying online, Pablo chose to implement a ketogenic diet instead. Two years later, he’s still miraculously alive. What’s more, the tumor is apparently not even growing. Plymouth Herald: Pablo, 27, Says His Survival After Terminal Diagnosis Is down to a Special Diet The idea behind using a ketogenic diet to stop tumor growth is that you can starve it by not feeding it sugar. Plus, lowering growth factors like insulin may also slow down growth. It might work in some instances, and in some not, as outlined in this article which we wrote a few weeks back: Can Low-Carb and Ketogenic Diets Be Helpful in Treating Cancer?. Note that Pablo is a case where conventional chemotherapy would have a moderate effect at best, with no hope of a cure. In many other situations conventional cancer treatment is very effective, offering excellent odds of beating the disease. Turning down treatment in such cases would be a very bad idea. However, a ketogenic diet might be a potent weapon to use alongside other cancer treatments, at least in some cases. There would probably be much more research going on if it were a patentable drug instead of a simple diet. More More about keto and cancer Video Top videos about ketosis Continue reading >>
Can A Ketogenic Diet Treat Cancer?
Can a ketogenic diet treat cancer? And could a low-carb diet over the long term reduce the risk of ever getting cancer? Here’s a segment of my earlier interview with cancer researcher Professor Eugene J. Fine. Transcript Watch it You can watch the full, much longer, interview on our member site: Can a Ketogenic Diet Treat Cancer? – Full interview Start your free membership trial to watch it instantly – as well as over 120 video courses, movies, presentations, other interviews, Q&A with experts, etc. Continue reading >>
Ketogenic Diet & Cancer: Interpreting The Research For You
We recently covered the science and clinical research behind using keto to treat pediatric epilepsy. Recently, scientists, doctors, and dietitians have assessed how the ketogenic diet can be utilized to manage symptoms of cancer. Below we report the findings of their preliminary research. While it’s a stretch to say that keto cures cancer, in some cases, it might be a useful complement to conventional cancer treatments. The Basic Facts of Cancer Before delving into the clinical research between carbohydrate restriction and cancer, let us review the basic facts about cancer. Cancer is a broad disease group of diseases characterized by uncontrolled cell growth. These cells grow unchecked and start to inhibit the function of healthy cells. Over time, this may eventually take a toll on the human body and lead to life-threatening symptoms. Cancer can start in most parts of the body where there is cell growth. Cancer cells typically form a lump called a neoplasm. People commonly call neoplasms “tumors.” Scientists refer to tumors that do not spread to other parts of the body as “benign tumors.” These are not cancerous. Tumors that do spread to other parts of the body are cancerous and called “malignant tumors.” There are over 100 documented forms of cancer with the five most common worldwide being lung, breast, colorectal, prostate, and stomach.  In 2012, over 14 million new cases of cancer were diagnosed worldwide (excluding some forms of skin cancer).  It inflicted about 8.2 million human deaths, or about 14.6% of human deaths, worldwide in 2012.  Sugar & Cancer: The Warburg Effect Cancer is a complex disease with many different underlying causes and contributing factors. One of the first observations about the disease was that cancer cells produce en Continue reading >>
When Should One Do A Keto Diet?
The keto diet seems to be an extreme offspring of the paleo movement. Like anything, there can be too much of a good thing. If low carb is good then extreme low carb enduced ketosis sounds even better. But, like taking anything to an extreme, there are side effects and unintended consequences. In the case of this diet, long term effects might include liver issues (indicated as "heat" in eastern medicine) and possonly a reduced tolerance for the "illegal" foods if and when they are reintroduced. Please do not quote me on this as I am neither a doctor nor have a thorougly or scientifically researched this topic. My comments are anecdotal and not derived from properly designed studies. Anyway... I do think there are therapeutic uses for this diet. As a previous commenter wrote, it can be used to prevent seizures. It might be appropriate for a diabetic looking for an alternative to using insulin. I have heard of it being used to stop the progression of alzeheimers although I have no evidence to support this other than that I heard about it from an eager and qualified medical researcher. In other words, it can be used as a therapy or like a medicine. Is is it a good idea to go on this diet just because you want to loose weight? Well, in my opinion no temporary diet nor any extreme diet is healthy or sustainable. Only incremental steps toward a sustained healthy lifestyle that includes a good, balanced diet will work to achieve stable normal weight in the long term. As for the prevention of disease, many claims are being made that this diet can prevent/cure cancer and other chronic diseases. While this is possibly true, it isn't to say that other diets cannot achieve the same and it isn't to say that good or even optimal health can be achieved even if you still eat sandwiches Continue reading >>
Seyfried’s Cancer Diet: My Fasting Jump-start To Ketosis
Dr. Seyfried’s book, Cancer as a Metabolic Disease, inspired me to attempt a fasting jump-start to ketosis to see how long it takes to achieve his “zone of metabolic management.” Read on to see how it’s going so far! (I’m still alive…) Note: this post was originally published on Aug 1, 2013. It was edited to streamline content and improve graphics, then re-posted in June 2016, therefore some older comments may pertain to content that was removed during revision. Dr. Seyfried’s Ketogenic Diet for Cancer Caution: dietary experiments with fasting and ketosis are best done under medical supervision, particularly if you have a medical condition or take any daily medications. Everyone’s metabolism is different, so results will vary. Please see my post “Is the Ketogenic Diet Safe for Everyone?” After reading Dr. Seyfried’s book,1) I immediately felt sympathy for those of you out there who have cancer now, or who are cancer survivors worried about recurrence—were you hoping for a simple nutritional strategy, such as “eat more broccoli” or “add chia seeds to your morning smoothie?” Had I led you down a road of hope and then left you feeling disheartened when you saw how difficult Dr. Seyfried’s diet appeared to be? Let me try to make it up to you by trying his diet myself while you watch from the comfort of your living room. Seyfried’s Fasting Jump-Start to Ketosis Dr. Seyfried says the fastest way to achieve optimal blood glucose and ketone levels is to begin with a water-only fasting jump-start to ketosis for 3-5 days, and then embark on a low-calorie “ketogenic” diet, aiming for blood sugar levels of 55-65 mg/dL and blood ketone levels of at least 4.0 mM (see article 3 of my cancer series for more details). As a reminder, average blood Continue reading >>
No Sugar, No Cancer? A Look At The Evidence
Eating lots of refined carbohydrates, including foods with added sugar, can lead to obesity. There’s a lot of confusing and misleading information on the Internet about the relationship between sugar and cancer. The notion that refined sugar causes cancer or that cutting sugar from the diet is a good way to treat cancer are two common — and incorrect — claims that turn up in a Google search. That’s unfortunate, because there is important, real science to understand about diet and cancer. To help sort out fact from fiction, we spoke with MSK President and CEO Craig Thompson, who studies the relationship between metabolism and cancer. What, if any, is the link between sugar and cancer? There is no question that obesity is associated with an increased risk of cancer, and that the abundance of carbohydrates in our diet is one of the major foundations on which the worldwide epidemic of obesity is built. The fundamental basis of obesity is eating more calories than you can burn over a period of time. Many people assume that if a person has a lot of body fat, it’s because they ate too much fat. That makes intuitive sense, but it isn’t the truth. Pretty much all you do with fats that you eat is burn them for energy. The fats you put into your fat cells are by and large made from carbohydrates. But it took us 25 years to figure that out. And as we learned recently, some groups tried to discourage or prevent that research. How did we get into this obesity trouble? As we emerged as a major agricultural nation after World War II, the United States was able to produce a tremendous amount of grains. And the caloric value of grains is not in their protein or in their fats primarily, but in their carbohydrates. We also learned that we could refine those carbohydrates into t Continue reading >>
Could A Change In Diet Cure Your Dog’s Cancer?
0 In an unassuming gated compound in Georgetown, Texas, something amazing is taking place. KetoPet Sanctuary is taking in shelter dogs with incurable, terminal cancer—dogs with no other options who would otherwise be euthanized—and giving them a second chance, providing them with state of the art cancer treatment to miraculous result. Upon pulling up at the sanctuary, located along a rural road 45 minutes outside of Austin, Texas, pretty much the first thing one notes is the enthusiasm of all present. The team’s passion and excitement is contagious. Also visiting are representatives from two local shelters, both of which have sent their dogs with cancer to the sanctuary for treatment. They sing glowing praises of the efforts of the KetoPet team. Together we wander the idyllic 53-acre facility, currently housing 26 dogs undergoing cancer treatment, including Pit Bull-mix Bill Murray and white-muzzled Dachshund cross Martha, petting dogs and getting the low-down on the ground-breaking work being done here. The foundation of the KetoPet Sanctuary’s cancer-fighting approach is the ketogenic diet, which is designed to slow or halt tumor growth. The diet looks like this: 80 to 90% fat (oil such as coconut, olive or MCT), 5 to 15% protein (beef) and 5% carbohydrates (vegetables). Yes, the diet is extreme, but with reason. It’s predicated on the Warburg theory, put forth by Otto Warburg in 1924. Warburg hypothesized that cancer feeds on sugar (which is what carbohydrates break down to) but that it doesn’t process fats well. The takeaway: cut out the sugars/carbs and you’ll slow or stop the cancer. All the dogs have weekly blood work done to monitor and evaluate the metabolic impact of the diet. CT and PET scans, conducted every 60 days, evaluate their cancers and Continue reading >>
What Are The Health Benefits Of Fasting?
For the sake 7% of the world’s population that denies the presence of any deities this article might convince them to fast. For the rest of the population, a spiritual aspect associated with fast is enough for them to continue this ritual of ‘Fasting’. According to the Medical News Today, numerous studies have suggested that intermittent fasting - abstaining or reducing food and drink intake periodically - can be good for us, making it one of the most popular diet trends worldwide. Here are some of the reasons to include fast in your dieting schedule: Fasting helps to lose weight As the body absorbs fat which it reserves for the situation like this. Lower level of insulin combined with increase in growth hormone and sending of norepinephrine by the nervous system to fat cells results in the fat to dissolve in absorbable energy. Thus it results in weight loss. Reduces Insulin Resistance Insulin resistance means the resistance of cells to the function of insulin of converting glucose in energy rather than storing it as a fat. To put it simply fasting improves the insulin sensitivity, maintaining the normal function of insulin intact and reducing sugar level in blood thus saving us from Type-2 Diabetes. Improves the Metabolism Toxic and Waste accumulated over a period of time due to eating is cleansed due to fasting. While the digestion system is resting during fast, the metabolism is energized to perform better. Normally fasting also improves digestive system helping us for better bowel movements. And who doesn’t wants to have a great start of the day? Beneficial to heart Cholesterol levels in body, blood pressure, Triglyceride and Inflammation are all risk factors for heart and by fasting, all can be controlled and indirectly that keeps us away from heart disease Continue reading >>
Rhr: The Ketogenic Diet And Cancer
The conventional view of cancer is that it is caused by DNA mutations in the cell nuclei. However, the metabolic theory of cancer proposes that some cancers are caused by a dysfunction of cellular respiration and that the restriction of glucose in the diet may prevent and even reverse some cancers. Today I’ll review the research supporting this theory and explore how the ketogenic diet may impact cancer tumor growth. In this episode we discuss: A disorder of energy metabolism Metabolic dysfunction may be a root cause How the ketogenic diet can help Existing research on keto and cancer Additional evidence supporting the metabolic theory Why keto alone may not be enough Chris Kresser: Hey, everybody, Chris Kresser here. Welcome to another episode of Revolution Health Radio. Today, we have a question from Kelsey. Let’s give it a listen. Kelsey: Hi, Chris, I was just wondering about your thoughts on the ketogenic diet as an approach to cancer prevention and therapy. I just read something about how cancer cells can only thrive on glucose, and in its absence we can prevent cancer potentially. So I was wondering if you could discuss this in a podcast. I think that would be great. Thank you. Chris: Okay. Thanks, Kelsey, for sending that question in. It’s a really great question, one that’s been on my mind a lot recently, actually, and I’ve been diving into the research on. Most of you probably know that cancer dogma holds that malignancies are caused by DNA mutations inside the nuclei of cells and that these mutations ultimately lead to runaway cellular proliferation, which is the hallmark feature of cancer. A disorder of energy metabolism But there are some cancer biologists out there that feel that while mutations are ubiquitous in cancer, they may not be the primar Continue reading >>
My Love – Hate Relationship With The Ketogenic Diet
There are always new diets popping up everywhere. One diet that recently caught my attention was the Ketogenic Diet. Since I have experimented with just about every diet out there, I wanted to experience first hand what it was all about. Since we are now understanding that cancer is a metabolic dis-ease and basically a dis-ease of insulin resistance, carbohydrate intolerance and inflammation, the low carb approach of the Ketogenic Diet made sense to me. Plus, there is more and more science to back it up. I have just spent the last three months with a Ketogenic Diet Coach exploring this very low-carb, low sugar way of eating. What I discovered about my own body based on how I responded to it was very eye-opening. What is the Ketogenic Diet? This form of eating was actually developed close to one hundred years ago as an effective way to treat and heal epilepsy. Today there are dozens of studies that confirm its long-term effectiveness at preventing epileptic seizures and other complications of this disease, especially in children for whom conventional treatment has not been effective. Studies have also shown the diet’s effectiveness on migraine headaches, narcolepsy, Retts syndrome, Dravett Syndrome, COPD, and Type 1 Diabetes. Recent studies have are also beginning to confirm its effectiveness at slowing cancer tumor growth as well. The Ketogenic Diet is high in healthy fats, moderate in protein and very low in carbohydrates (20-50 grams per day, depending on your weight) . When a person eats this way, their body is forced to burn fats instead of carbs (glucose) for fuel. Fewer carbs and glucose to use as fuel affects the liver; it will then begin to change fats into fatty acids and eventually into what are called “ketone bodies” which are water soluble fats. Accord Continue reading >>
Scientists Studying Effect Of Ketogenic Diet On Brain Cancer
Scientists are tracking the effects of a high-fat, low-carbohydrate diet for its potential to starve brain tumours and treat cancer patients. The ketogenic diet was developed in the 1920s to help people with epilepsy. It works by forcing the body to burn fats rather than carbohydrates. Normally, the body converts carbohydrates into glucose. But a low-carbohydrate diet causes the body to convert fat into fatty acids and ketone bodies; the latter acts as a replacement for glucose. High levels of ketone bodies are associated with reduced seizure frequency. It is theorized that the ketogenic diet could be used to "starve" some forms of cancer. Cancer cells use to glucose to grow, and they’re inefficient at using ketone bodies for energy So far, the diet’s effects on cancer cells has only been examined in animals and noted only anecdotally in human cases. A 2012 study on mice found that the ketogenic diet "significantly enhances" the anti-tumour effect of radiation. Dr. Jong Rho, head of pediatric neurology at the Alberta Children's Hospital, previously used the diet to treat patients with epilepsy and was part of the 2012 study. Rho has also been monitoring the case of 15-year-old Adam Sorenson. More than two years ago, the Calgary teen was diagnosed with Stage 4 glioblastoma multiforme, the most common and aggressive form of brain cancer. The average time of survival after diagnosis is 12 to 15 months. Following Adam’s diagnosis, doctors performed surgery to remove a baseball-sized brain tumour. Sorenson then received radiation treatment. Chemotherapy was an option, but tests suggested he might not benefit. With few options left on the table and a real chance the cancer would return, Sorenson's parents did some research and put their son on the ketogenic diet. "You f Continue reading >>
Could A Ketogenic Diet Cure Your Dogs Cancer?
For decades, dog owners have been following one new diet trend after another. From grain-free to raw and limited-ingredient diets, there’s always something new to try. More recently, people have begun to feed their dogs a ketogenic diet as a way to treat or cure their cancer. There is no question that what we feed our dogs impact their health but will feeding a dog with cancer a ketogenic diet cure them? Read on to find out. What is a ketogenic diet? A ketogenic diet is one that’s high in fat, contains moderate levels of proteins and is very low in carbohydrates. But why feed your dog such a diet? What does giving them fewer carbs and more fat lead to? All of the cells in our body need energy to grow and survive. They get this energy from different sources. The primary source from which cells derive energy is glucose, a simple sugar that circulates in the blood. It get broken down into various products and ultimately produces energy which the body’s cells use a fuel to carry out their various functions. Carbohydrates are a good source of glucose. So when you feed your dog carbohydrates, they’re digested and broken down into glucose which provides your dog’s cells with the energy they need. But when the availability of carbohydrates is limited, an alternative source of cellular energy is needed. This alternative source is usually fat. When fats rather than carbohydrates are used for energy, it results in the production of glycerol and fatty acids, rather than glucose. It also pushes the body into the metabolic state called ketosis. During ketosis, fats are metabolised (broken down) by the liver, which leads to the production of ketone bodies. These ketone bodies are then transported via the blood to tissues, where they’re eventually converted into energy. Amo Continue reading >>
How The Ketogenic Diet Weakens Cancer Cells
Chronic disease continues to ravage our world today despite tremendous advances in health care. Therapeutic approaches to treating this wide-range suffering cannot be met by technological growth in pharmacology, genetic therapy, or surgery. It should be obvious that the real solution for treating cancer and disease is not found in a man-made pill but rather is found in regulating the metabolic functions within our bodies. Western cultures today enjoy a diet rich in the delicacies that our ancestors did not consume on a regular basis such as grain, sugar, and starch. Research continues to show that sugar is the main source of fuel which feeds cancer and contributes to an inflammatory environment. Sugar essentially increases the risk for cancer and disease. How the Ketogenic Diet Works What is the Ketogenic Diet? The Eskimos and Maasai group are cultures we often look at to learn how their scant consumption of carbohydrates sustained their bodies through harsh weather conditions. It turns out that their low carb diet switched their metabolism to burn fat instead of sugar or glucose. This created a metabolic state known as ketosis, a process in which the body burns ketones to make energy, instead of relying on sugar or carbohydrate. Ketones are metabolized by fatty acids in the liver for energy. (This source of fuel is capable of crossing the blood brain barrier and is an excellent form of energy for neurons.) When the body lacks glucose, which is its first source of fuel, ketones are created in its absence. Ketosis was a beneficial process the human body developed as an adaptation to times when food was unavailable (such as for these hunter-gatherers). However, you can effectively produce ketones too by limiting the carbohydrates in your diet to less than 80 grams daily a Continue reading >>
Ketogenic nutrition is a nutrition-therapeutic approach to support conventional cancer treatment. The outstanding feature of this nutritional therapy is that it specifically impacts the metabolic properties of cancer cells and exploits the “weaknesses” of these metabolic changes. → What does ketogenic nutrition mean? → From the hypothesis to the nutrition concept → Survival benefit sugar fermentation → Growth factor insulin → Ketogenic nutrition in stead of fasting → What are the evidences of its efficiency so far? → Why is it worthwhile to try it out? Cancer cells absorb enormous quantities of sugar in the form of glucose (grape sugar) compared to the surrounding tissue to secure their increasing energy requirement for growth and reproduction. However, while most healthy cells “burn up” nutrients, many cells, especially aggressive, metastatic and therapy-resistant cancer cells show an unusually high rate of fermentation of sugar, even in the presence of oxygen . Recent studies could clarify that the cancer cells, in switching over to this alternative energy source, protect themselves against oxidative stress  . At the same time, by doing this, they inhibit the efficiency of many chemotherapy drugs and radiation forms. On the basis of these findings, the concept evolved to deprive cancer cells of the important energy suppliers through a significant reduction in sugar intake, for example to increase oxidative stress in the tumour cell   . → An important note in advance: Ketogenic nutritional concepts serve only to support one therapy proposed by a treating oncologist. By choosing foodstuffs rich in energy and nutrients, they are to help to strengthen the physical condition of the patient and to improve the tolerance as well as th Continue reading >>
New Publication : Ketogenic Diets And Cancer – February 2017 Issue Federal Practitioner
I invite you to take a look at my latest publication, entitled “Ketogenic Diets and Cancer – Emerging Evidence”. It appears in the February 2017 issue of the Federal Practitioner. What is this all about? This review article summarizes most of what we know today regarding ketogenic diets and how they may benefit cancer. It contains a brief history of the ketogenic diet, detailed explanations on how it might work to slow down cancer, and examples of animal and laboratory studies involving the diet in cancer investigation. Also included are human case reports and summaries of existing and recently completed clinical trials involving ketogenic diets and cancer. The link to the online article is available below. Can ketogenic diets replace chemotherapy? While many would conclude that diets can “cure” cancer, it cannot. At least not yet. The trials listed in this article are still going on. Many of the completed ones, tested for safety and tolerability only, and did NOT specifically test whether the diet can actually improve a particular cancer. Follow the advice of your cancer doctor. Chemotherapy and radiation are still very much the treatment of choice for cancer. Diet changes (low carbohydrate or ketogenic diets) are meant to be used in addition to chemotherapy and radiation, and not to replace them! Ketogenic diets, are they safe? Yes, based on the available completed safety trials, ketogenic or low carbohydrate diets are probably safe to use in cancer patients who, other than having cancer, are otherwise in good health! The diet however, is not easy to follow. A family member who is highly motivated to help, can be a key factor to successful dieting. Is this diet right for me? Results may vary. Always consult with your medical oncologist (cancer doctor), wheth Continue reading >>