diabetestalk.net

Can Ketosis Cause Gout

1: Kidney Stones, Gout, & Heart Palpitations On Keto

1: Kidney Stones, Gout, & Heart Palpitations On Keto

Today we officially kickoff this brand new podcast dedicated to answering listeners questions about the low-carb, moderate protein, high-fat, ketogenic diet. It’s called Keto Talk with Jimmy Moore & The Doc (now available to listen and subscribe on iTunes) featuring 10-year veteran health podcaster Jimmy Moore from “Livin’ La Vida Low-Carb” and Arizona osteopath and bariatric physician Dr. Adam Nally from “Doc Muscles.” These two are a keto power pair ready to take on your most pressing questions about this way of eating. KEY QUOTE: “If you cheat on your ketogenic diet, then you are at risk of a kidney stone or gout. The point is if you’re gonna cheat, you’re gonna pay for it.” — Dr. Adam Nally Here’s what Jimmy and Adam talked about in Episode 1: – The beginning of this new podcast devoted to keto – How Adam uses ketogenic diets with his patients – Adam’s father who died early from diabetes issues – Follow Jimmy and Adam on Periscope – Whether keto creates or prevents kidney stones – Why it’s not a good idea to cheat on your low-carb diet – How cheating, not keto, is what leads to gout – Whether a ketogenic diet causes heart palpitations – How to best balance your electrolytes starting keto – The problem with caffeine on your cortisol levels WORLD’S 1ST REUSABLE BREATH KETONE ANALYZER NOTICE OF DISCLOSURE: Paid sponsorshipTHE WORLD’S FIRST EXOGENOUS KETONES SUPPLEMENT NOTICE OF DISCLOSURE: Paid sponsorshipLINKS MENTIONED IN EPISODE 1 – SUPPORT OUR SPONSOR: Get the 2015 Ketonix breath ketone analyzer from Ketonix.com – SUPPORT OUR SPONSOR: Try the KETO//OS exogenous ketones supplement – Jimmy Moore from “Livin’ La Vida Low-Carb” – Dr. Adam Nally, DO from DocMuscles.com – Jimmy Moore on Periscope Continue reading >>

Too Many Carbohydrates Cause Gout

Too Many Carbohydrates Cause Gout

What is Gout? Gout is a common form of arthritis that has been recognized for centuries. Patients often will complain of experiencing recurrent episodes of pain and inflammation in a joint, particularly the large toe and usually lasts for 1-2 weeks. It is often associated with obesity and excessive alcohol consumption. The incidence of gout seems to be increasing along with the incidence of obesity and diabetes in the U.S. Although men are affected more often than women, many women suffer from gout as well. Pain and Inflammation The pain of gout is due to an inflammatory reaction triggered by a buildup of uric acid in the joint. Uric acid (otherwise known as urate) is a normal waste product of protein metabolism. When concentrations of uric acid build up in the blood stream, they seep into the fluid of our joints and can trigger a painful inflammatory reaction. Why the reaction often occurs first in the joint of the large toe is generally unknown. It can also occur in the ankle initially and less commonly the knee. The conventional approach to the treatment of gout is to provide medications that either reduce inflammation during an acute episode of pain or lower the level of uric acid in the blood. Both approaches help reduce the pain and frequency of attacks but neither addresses the underlying cause of gout. Too Many Carbohydrates Cause Gout For centuries, gout has been associated with obesity and overindulgence in alcohol. As I have discussed before, obesity is linked to development of insulin resistance which also causes elevated triglycerides, high blood pressure, diabetes, stroke, chronic kidney disease and heart attacks and elevated uric acid levels. The greater the degree of obesity, the more likely a person seems to be predisposed to develop gout. Elevated insu Continue reading >>

Will Ketogenic Diet Cause Gout?

Will Ketogenic Diet Cause Gout?

While initially there may be an increase in uric acid that usually subsides when you become fat adapted. Being on a ketogenic diet does not mean your intake of meat should be high. Most meats are predominantly protein, so you should not use meat as a primary fat source. If you find yourself consuming meat and dairy at almost every meal then you have a problem. You are not only increasing the acidity in your system by creating more uric acid, but you are also straining you GI tract, liver, and kidneys. Make sure to get your fats from quality sources like avocado, coconut, flax, chia, olive oil, butter, and grass fed meats.Eating a diet predominantly made up of meat is also disastrous because you are depriving your body of important micro-nutrients,minerals, and antioxidants. You have to increase your intake of vegetables to make up for the over-consumption of animal products. You need to calculate how much protein your body needs for muscle maintenance and stay at that level. Consuming too much protein from meats will also force your body to convert the excess into glucose, which may kick you out of ketosis. Continue reading >>

Does Keto Cause Gout? Day 2 Of Vlogust

Does Keto Cause Gout? Day 2 Of Vlogust

So yesterday I had a gout attack. I've had gout for the past 10 years, long before I started the ketogenic diet. When I first started the keto diet 15 months ago I had a touch of gout here and there but nothing too bad. Yesterday and today was a bad one though. In this video, I talk about why I think it happened and what I'm going to do about it. I'd love to hear in the comments if you think Keto causes gout and if any of you have experienced it while on Keto. Continue reading >>

Dear Mark: Risk Of Gout?

Dear Mark: Risk Of Gout?

Every so often, a health malady arises that seems to clash with Primal living. And when a doctor brings it up, or a family member with intimate knowledge of the illness expresses concern, it can be intimidating and troubling. We’ve all heard how we’ll suffer heart attacks, diabetes, ketoacidosis, lowered marathon performance, kidney disease, and osteoporosis from “eating all that meat,” but that’s not what I’m covering today. No, today the subject is gout, which occurs when excess uric acid crystallizes and accumulates in the extremities. The jagged shards embed themselves in the joints, tendons, and other tissues, causing excruciating pain, inflammation, and swelling, particularly in the big toe. Suffice it to say, it is extremely unpleasant. Sounds great, right? Let’s move on to the question that prompted today’s post: Hi Mark, What’s your take on gout? It apparently runs in my family, and while I haven’t gotten an attack yet, I’ve heard that a “rich diet” is the cause, which as I understand refers to meat and animal fat. Does this mean I shouldn’t eat Primal? What does the science actually say? Thanks, Will In previous centuries, gout was described as a “rich man’s disease” or “the disease of kings.” Ambrose Bierce called it “A physician’s name for the rheumatism of a rich patient.” Basically, it primarily affected the upper class, the royalty, the aristocracy – those who could afford “rich” foods like meat, sugar, and port. In the mid-19th century, uric acid was identified as the causative agent in gout. Where does uric acid come from? Purines. Purines are in pretty much every cell – plant and animal alike – because they provide some of the chemical structure of both DNA and RNA. When cells are broken down and re Continue reading >>

Steve Phinney And Richard Johnson: Ketones, Uric Acid, High Fat And Health

Steve Phinney And Richard Johnson: Ketones, Uric Acid, High Fat And Health

Note from Steve Phinney: What this shows is that uric acid goes up promptly in the same time frame that ketones go up, but after 4-6 weeks, despite ketones staying up, uric acid starts to come back down. Based on these data and my clinical observations in thousands of patients, uric acid returns to or below pre-diet baseline within 6-12 weeks despite the person remaining is a state of nutritional ketosis. Thus, when I’m asked how long ketoadaptation aks, I generally respond that some aspects of it take 6 weeks or more. This graph, by the way, shows blood uric acid levels from the untrained subjects (VT) and bicycle racers (MIT) at various times over 4-6 weeks of sustained carbohydrate restriction (aka keto-adaptation). LISTEN (50 Minutes) EDITOR’S NOTE: Sometimes, the divide between experts who advise against a high-fat, low-carb diet and those who recommend it seems larger than the Grand Canyon. But occasionally, top thinkers from both sides break through to discover common ground, along with new paths for exploration. With that in mind, here’s a discussion between two nationally recognized health researchers which refers to the uric data in this chart . . . and more. To see the charts in larger format, click on them, and they should enlarge. Before going to the transcripts of this interview, here’s more background: Dr. Steve Phinney is emeritus professor of medicine at UC-Davis and a world-renowned expert on high fat diets, including how they affect uric acid levels. Dr. RIck Johnson is a professor of medicine at the University of Colorado who’s an expert on fructose metabolism (fructose accounts for much of the sweetness in table sugar and in high fructose corn syrup). Johnson’s expertise on fructose ties him back to uric acid. Johnson writes: “Our work Continue reading >>

Gout And Keto

Gout And Keto

There’s loads more to it than simply blaming red meat or whatever is this weeks uric acid demon food. Some people with high uric acid never experience gout, whilst others with low levels get it often – and vice versa, it’s all about CLEARANCE and avoiding the feedback loop. Simply put – swapping out pig for fish won’t fix the clearance issue, it may reduce the build-up ever so slightly, but I seriously doubt it. Short version for ketards is ketones compete with uric acid for flushing, so that period where you are just acclimatising is when it’s most likely. Once you are using your ketones effectively the uric clearance thing isn’t an issue. The worst thing someone susceptible to gout can do is go back and forth from carby to keto and never fully adapt – this is gout limbo, and I’m guessing a good way to develop kidney stones in the long term. As it stands I consider it a catalyst feature – as in whatever susceptibility I have toward joint issues lays dormant until something ELSE happens. One catalyst that semi-correlates is food, each of the last few times I’ve experienced pain it’s been within a day or two of Thai food – but a confounder is that each time I also drank a bunch of beer too. Another is 12+ hours on a chair when I’m in research and writing mode that promotes poor circulation, so probably inducing some kind of mild thrombosis which is enough to start a cascade of events that end up in inflammation of a joint/nerve. And each time seems to be within days where I’ve experienced a twisting/whatever of an ankle/knee too for some reason. It’s a reflective problem which gets itself into a feedback loop. I’ve researched far and beyond the whole “it’s cos you eat red meat and wine brah” thing from years ago, it’s nothing to Continue reading >>

Ketogenic Diet And Gout Risk — Tips For Success

Ketogenic Diet And Gout Risk — Tips For Success

Despite all the wonders of moving towards a high-fat, low-carb — ketogenic — diet, those who suffer from gout or other kidney problems are well advised to seek medical consultation before experimenting with this nutritional regime. Over the past several days, I have cited Rocco Stanzione’s informative Low Carb For Health. Stanzione wrote about the ketogenic diet in 2010. He also suffers from gout. Gout and the ketogenic diet In his article, ‘Gout’, he explains and advises (emphases mine): if you’re getting plenty of fluids, your kidneys are generally active enough to get rid of the excess uric acid produced by your diet. And if you’re getting plenty of exercise, the crystals likely won’t have a chance to form in the joints in the first place. There also seem to be some specific foods you can consume to lower your risk. Dairy products, for example, tend to decrease the amount of uric acid in your blood. Coffee has been shown to decrease your risk of getting gout in the first place, but no one seems to know why. Anecdotally, I’m pretty sure I can vouch for coffee as an effective treatment and preventative even after getting it, and this is possibly explained by the effects of caffeine on uric acid levels. And still other foods further increase your risk. These include organ meats such as liver and kidneys, which are very high in purines, and alcohol. The flare-up I’m presently suffering from happened to occur after an expense-account night at the bar, but I’m sure that’s completely unrelated. … More dairy products, more coffee, less alcohol. Milk, by the way, has lactose, a sugar that’s not compatible with a low-carb diet in high doses, so I recommend regular coffee with lots of heavy cream for two powerful nearly-carb-free preventatives at onc Continue reading >>

Ketogenic Diet And Vitamin C: The 101

Ketogenic Diet And Vitamin C: The 101

Written by Amber O’Hearn (MSc Computer Science). Find more of her writings at www.ketotic.org The Recommended Daily Allowances (RDA) for different nutrients were developed on Western diets, and therefore, high-carb diets. Given that a ketogenic metabolism uses different metabolic pathways and induces cascades of drastically different metabolic and physiological effects, it would be astonishing if any of the RDAs are entirely applicable as is. One micronutrient that seems to be particularly warranting reassessment is vitamin C, because vitamin C is biochemically closely related to glucose. Most animals synthesize it themselves out of glucose. It shares cellular uptake receptors with glucose. Some argue that because we don’t make vitamin C, we need to ensure a large exogenous supply. I will argue the opposite: so long as we are eating a low-carb diet, we actually need less. On our way, we’ll briefly re-examine the relationship between vitamin C deficiency and insulin resistance. Table of Contents Micronutrients matter Micronutrients matter There are particular nutrients people need to develop normally and stay healthy, that we can’t make in our own bodies, and so we have to get them from our diets. We only started recognizing this at the end of the 19th century. Before that, the germ theory of disease was new and exciting, and we wanted to explain all maladies as infections. However, we ultimately learned that some diseases come from malnutrition. The best exemplifiers of this are when people or other animals die for lack of one specific ingredient, as in pellegra, beriberi, rickets, and scurvy. These ingredients were named, initially, “vitamines”, meaning vital amines, but when it turned out they weren’t all amines, the name was shortened to “vitamins” Continue reading >>

The Ketogenic Diet Is A Natural Treatment For The Symptoms Of Gout

The Ketogenic Diet Is A Natural Treatment For The Symptoms Of Gout

A new study published in the journal Cell Reports suggests that a ketogenic (high fat, low carb) diet may be helpful in treating the symptoms of gout. Gout is something that plagues more and more people every day, and it’s caused from uric acid buildup in the body. What is Gout? Gout is a form of inflammatory arthritis that develops in some people who have high levels of uric acid in the blood. The acid can form needle-like crystals in a joint and cause sudden, severe episodes of pain, tenderness, redness, warmth and swelling Uric acid, a normal byproduct of metabolic processes, is typically dissolved in the blood and then excreted from the body through the urine. However, when the body is unable to properly break down uric acid, blood levels rise, and the excess is deposited in bodily tissues. When uric acid accumulates around the joints it is known as “tophi,” and can manifest as jelly like lumps under the skin. When uric acid crystals collect in the kidneys, it can result in kidney stones. The Role Of a Ketogenic Diet Ketogenic diet may protect against gout. … It is caused by either an excessive production or insufficient excretion of uric acid. In gout, the uric acid crystals sediment in tissues and fluids, triggering the body’s immune cells. Recent research out of the laboratory of Vishwa Deep Dixit, professor of comparative medicine and immunobiology at Yale School of Medicine in New Haven, CT, suggests that symptoms of gout may be managed with a ketogenic diet. Ketogenic diets are typically implemented for weight loss, or to treat childhood epilepsy. The diet involves a significant reduction of carbohydrate intake favoring moderate protein and high fat foods. This starves the central nervous system of glucose and prompts the liver to metabolise fats pro Continue reading >>

Study Identifies Natural Gout Remedy With This Diet

Study Identifies Natural Gout Remedy With This Diet

A new study published in the journal Cell Reports suggests that a ketogenic (high fat, low carb) diet may be helpful in treating the symptoms of gout. What is Gout? Gout is a form of inflammatory arthritis that results from an imbalance in the production and secretion of uric acid. Uric acid, a normal byproduct of metabolic processes, is typically dissolved in the blood and then excreted from the body through the urine. However, when the body is unable to properly break down uric acid, blood levels rise, and the excess is deposited in bodily tissues. The “needle-like” uric acid crystals irritate the area where they are deposited, triggering inflammation, swelling, and severe pain. When uric acid accumulates around the joints it is known as “tophi,” and can manifest as jelly like lumps under the skin. When uric acid crystals collect in the kidneys, it can result in kidney stones. The Role Of Ketosis Recent research out of the laboratory of Vishwa Deep Dixit, professor of comparative medicine and immunobiology at Yale School of Medicine in New Haven, CT, suggests that symptoms of gout may be managed with a ketogenic diet. Ketogenic diets are typically implemented for weight loss, or to treat childhood epilepsy. The diet involves a significant reduction of carbohydrate intake favoring moderate protein and high fat foods. This starves the central nervous system of glucose and prompts the liver to metabolise fats producing fatty acids and ketone bodies. This is referred to as the physiologic state of ketosis. The new study focuses on one of these ketone bodies in particular called beta-hydroxybutyrate, or BHB. The researchers suggest that BHB may be responsible for the noticeable effect of ketosis on the symptoms of gout. BHB, Inflammation, and Gout Episodes of immun Continue reading >>

How To Cure Gout

How To Cure Gout

How to Cure Gout Gout, or elevated levels of uric acid, is one of the most commonly mistakenly fixed with a diet that is low in protein and high in fructose. The prevalence of gout seems to have doubled over the last 25 years.Uric acid accumulates and crystallizes into needle-sharp urate crystals. These crystals then lodge in the soft tissues and in the joints of the extremities most commonly, the big toe. This causes inflammation, swelling and terrible pain. Uric acid is a breakdown of protein compounds known as purines; which are the building blocks of amino acids. High concentrations of purines are found in meat, SO we assumed that the primary cause of elevated uric acid levels in the blood is caused by an excess of meat consumption. The actual cause, has been quite shocking! Just as low sodium diet has been proven to NOT help with lowering blood pressure and a cholesterol-free diet doesn’t help with decreasing heart disease, a low-purine diet has no effect on uric acid levels! A vegetarian diet will drop serum uric acid levels by only about 10% compared to a typical American diet, but that isn’t going to do much to decrease the gout and the pain that is being experienced. Another shocking piece of evidence is that eating additional protein increases the excretion of uric acid from the kidney! This decreases the level of uric acid in the blood; therefore the high protein diets are helpful, even if the purines aren’t. Now let’s look at the true culprit…Insulin resistance DOES raise uric acid levels. This happens because it decreases uric acid elimination by the kidney; the same way it raises blood pressure by decreasing sodium excretion. So raised insulin levels will raise uric acid levels and can cause gout. Therefore a high carbohydrate diet is one large p Continue reading >>

Gout And Ketogenic Diet

Gout And Ketogenic Diet

How Gout and the Ketogenic Diet Affects You A ketogenic diet is a diet with extremely low or no carbohydrates diet which makes the body go into a state known as ketosis. When the body is in the state of ketosis, the carbohydrates levels are low and this causes the blood sugar levels to drop and the body begins to break down fat to produce energy. Normally, the body relies on dietary energy sources as well as on the stored energy, which in most cases is always in the form of stored fats. When the body is exposed to ketogenic diet, it implies that the dietary carbohydrates will be kept very low, thus leaving the body to rely on stored fats to provide the primary source of fuel, a process which also ends up producing ketones from the stored fats. It should be noted, therefore, that a ketogenic diet is a high fat diet and not a high protein diet as has always been portrayed. Studies have suggested that high fat low carb ketogenic diet can help to alleviate the symptoms of gout. Gout symptoms are normally triggered by the NLRP3 inflammasome with the aid of neutrophilis. What happens is that the NLRP3 activates the 1L-1B pro-inflammatory cytokine which then leads to bouts of intense pain at the joints, fever, as well as the destruction of the joints. According to the studies conducted on rodent models, researchers induced gout in rats by injecting 1.25mg of monosodium urate on the knee, after which the knee’s thickness was measured and pathology analysis performed on the menisci and the ligaments. Human subjects were also used during the research where steroid free adults between the ages of 18 and 45 years and adults above the ages of 65 years. All the participants in the studies were not fasting at the time when there peripheral blood was collected. The studies concluded Continue reading >>

The Symptoms Of Gout Are Related To Excess Uric Acid

The Symptoms Of Gout Are Related To Excess Uric Acid

Rates of gout have skyrocketed in the UK, rising 64 percent between 1997 and 2012 High levels of uric acid are associated with gout, and one of the primary ways that uric acid levels are increased is by eating too much fructose If you struggle with gout, eliminating or strictly limiting fructose is an important step to recovery First, cut out soda, fruit drinks, and other sweetened beverages, as these types of drinks are a primary source of excessive fructose By Dr. Mercola Rates of gout have skyrocketed in the UK, rising 64 percent between 1997 and 2012.1 That equates to about a four percent rise every year, and this painful condition now affects one in 40 people! Unfortunately, many of the media outlets that picked up this story have been focusing on the researchers' finding that access to medication was a problem, and rates of people using uric-acid-lowering medications remained "suboptimal." If you struggle with gout, as increasing numbers of people do, the message to take home is that you don't need to take drugs to deal with this potentially excruciating condition. You can address the underlying cause of excess uric acid formation through all natural means, and very effectively at that. Gout is, after all, primarily a lifestyle-related disease. Uric acid is a normal waste product found in your blood. High levels of uric acid are associated with gout, which is a type of painful arthritis and inflammation, and about half the time, targets the base of the big toe. It has been known for some time that people with high blood pressure, overweight, and people with kidney disease often have high uric acid levels as well. Uric acid functions both as an antioxidant and as a pro-oxidant once inside your cells. So, if you lower uric acid too much, you lose its antioxidant ben Continue reading >>

Will Eating A Paleo Diet Cause Gout?

Will Eating A Paleo Diet Cause Gout?

This article is part of a special report on Red Meat. To see the other articles in this series, click here. A common question I get from readers is whether a Paleo-type diet will increase their risk for gout. Gout is a type of inflammatory arthritis caused by elevated levels of uric acid in the blood, forming crystal deposits in the joints, tendons, and surrounding tissue. Gout typically affects the feet in general and big toe joint specifically, and causes severe pain and swelling. In the past, gout was referred to as a “rich man’s disease”, as it typically affected the upper class and royalty who could afford “rich” foods like meat, sugar, and alcohol. Uric acid is a byproduct of the metabolism of purines, one of two types of nitrogenous bases that form the basic structure of DNA and RNA. While purines are present in all foods, they are typically higher in many of the foods emphasized on a nutrient-dense Paleo diet, such as red meat, turkey, organ meats, and certain types of fish and seafood. Patients with gout are often advised to reduce or eliminate these purine-rich foods with the goal of preventing excess uric acid production, thereby reducing the symptoms of gout. And research has confirmed the association between high purine intakes and acute gout attacks, suggesting that those diagnosed with gout would benefit from a reduction in purine-rich foods. (1, 2) So, do we need reconsider recommendations to eat foods like liver, sardines, red meat, mussels, and other traditional foods? Do these nutrient-dense, purine-rich foods really cause gout? Are those of us following a Paleo-style diet putting ourselves at greater risk for this painful, debilitating condition? Does eating meat and fish increase your risk for gout? Inflammation as a cause of gout attacks Continue reading >>

More in ketosis