How To Manage Diabetes While On Oxycodone
What happens to a person’s blood sugar when they are under stress due to pain, and must take a narcotic pain reliever such as oxycodone? In this article, we will explore what happens to a person with diabetes who is taking long term pain medication. We will look at whether it raises or lowers blood glucose. We will look at how taking oxycodone affects blood glucose levels, activity levels and appetite, and how that could influence the self-management of diabetes. We will look at ways that you can maintain blood glucose in target ranges while taking a narcotic pain reliever such as oxycodone. John’s story As John relayed to me during a phone conversation, he is taking a combination of oxycodone plus acetaminophen for severe pain in his legs related to poor circulation and neuropathy because of his Type 1 diabetes. He has had severe sleep disruption, and was getting no relief on nonsteroidal anti-inflammatory agents. He has been taking oxycodone now for about three months, and has seen a need to increase the basal rate on his insulin pump in order to stay in target range with his blood glucose. He found that once the stress of the pain was gone, his numbers have stayed in range. I suggest reading the following: What is oxycodone? Oxycodone is a narcotic pain reliever that is used to relieve moderate to severe pain. It is in the class of drugs called “opiate analgesics,” and can be found in combination with other nonsteroidal anti-inflammatory medications such as aspirin, acetaminophen, or ibuprofen. Oxycodone can also be found in combination with aspirin and acetaminophen. Each of these components can also have side effects in addition to the oxycodone. Brand names of combination medications include Nortab, Vicodin, and Lortab and Percocet. Precautions for oxycodo Continue reading >>
Diabetes - Type 2
Description An in-depth report on the causes, diagnosis, treatment, and prevention of type 2 diabetes. Alternative Names Type 2 diabetes; Maturity onset diabetes; Noninsulin-dependent diabetes Highlights Diabetes Statistics According to the U.S. Centers for Disease Control and Prevention’s (CDC) National Diabetes Fact Sheet, nearly 26 million American adults and children have diabetes. About 79 million Americans aged 20 years and older have pre-diabetes, a condition that increases the risk for developing diabetes. Diabetes and Cancer Type 2 diabetes increases the risk for certain types of cancer, according to a consensus report from the American Diabetes Association and the American Cancer Society. Diabetes doubles the risk for developing liver, pancreatic, or endometrial cancer. Certain medications used for treating type 2 diabetes may possibly increase the risk for some types of cancers. Screening for Gestational Diabetes Mellitus The American Diabetes Association recommends that pregnant women without known risk factors for diabetes get screened for gestational diabetes at 24 - 28 weeks of pregnancy. Pregnant women with risk factors for diabetes should be screened for type 2 diabetes at the first prenatal visit. Aspirin for Heart Disease Prevention The American Diabetes Association now recommends daily low-dose (75 - 162 mg) aspirin for men older than age 50 and women older than age 60 who have diabetes and at least one additional heart disease risk factor (such as smoking, high blood pressure, high cholesterol, family history, or albuminuria). Guidelines for Treatment of Diabetic Neuropathy The anticonvulsant drug pregabalin (Lyrica) is a first-line treatment for painful diabetic neuropathy, according to recent guidelines released by the American Academy of Neurol Continue reading >>
14 Ways To Reduce Joint Pain With Diabetes
Diabetes can damage joints, making life and movement much harder. How does this happen, and what can we do about it? A lot. “Without properly functioning joints, our bodies would be unable to bend, flex, or even move,” says Sheri Colberg, PhD, author of The Diabetic Athlete, The 7 Step Diabetes Fitness Plan, and other books. Joint pain is often called “arthritis.” “A joint is wherever two bones come together,” Colberg writes. The bones are held in place by ligaments, which attach bones to each other, and by tendons, which attach bones to the muscles that move them. The ends of the bones are padded with cartilage, a whitish gel made from collagen, proteins, fiber, and water. Cartilage allows bones to move on each other without being damaged. Joint cartilage can be damaged by injuries or by wear and tear with hard use. “Aging alone can lead to some loss of [the] cartilage layer in knee, hip, and other joints,” says Colberg “but having diabetes potentially speeds up damage to joint surfaces.” Sometimes extra glucose sticks to the surfaces of joints, gumming up their movement. This stickiness interferes with movement and leads to wear-and-tear injury. High glucose levels also thicken and degrade the collagen itself. This is bad because tendons and ligaments are also largely made from collagen. Reduced flexibility of joints leads to stiffness, greater risk of physical injury, and falls. People with joint damage may reduce their physical activity due to discomfort and fear of falling. Reduced activity promotes heart disease and insulin resistance. Here are 14 things we can do to prevent and treat joint problems and to keep moving. • Stretching keeps muscles and tendons relaxed and aligned so they’ll move as needed. You might want to ask a physical ther Continue reading >>
- 14 Ways to Reduce Joint Pain With Diabetes
- Do Simvastatin Side Effects Include Diabetes and Joint Pain?
- Is it possible to catch diabetes? It sounds absurd, but that's what a reputable new study suggests. And it may be that other 'lifestyle' diseases such as joint pain and even obesity are contagious, too
The Emedicinehealth Doctors Ask About Diabetic Ketoacidosis:
A A A Diabetic Ketoacidosis (cont.) A person developing diabetic ketoacidosis may have one or more of these symptoms: excessive thirst or drinking lots of fluid, frequent urination, general weakness, vomiting, loss of appetite, confusion, abdominal pain, shortness of breath, a generally ill appearance, increased heart rate, low blood pressure, increased rate of breathing, and a distinctive fruity odor on the breath. If you have any form of diabetes, contact your doctor when you have very high blood sugars (generally more than 350 mg) or moderate elevations that do not respond to home treatment. At initial diagnosis your doctor should have provided you with specific rules for dosing your medication(s) and for checking your urinary ketone level whenever you become ill. If not, ask your health care practitioner to provide such "sick day rules." If you have diabetes and start vomiting, seek immediate medical attention. If you have diabetes and develop a fever, contact your health care practitioner. If you feel sick, check your urinary ketone levels with home test strips. If your urinary ketones are moderate or higher, contact your health care practitioner. People with diabetes should be taken to a hospital's emergency department if they appear significantly ill, dehydrated, confused, or very weak. Other reasons to seek immediate medical treatment include shortness of breath, chest pain, severe abdominal pain with vomiting, or high fever (above 101 F or 38.3 C). Continue Reading A A A Diabetic Ketoacidosis (cont.) The diagnosis of diabetic ketoacidosis is typically made after the health care practitioner obtains a history, performs a physical examination, and reviews the laboratory tests. Blood tests will be ordered to document the levels of sugar, potassium, sodium, and oth Continue reading >>
Can Inflammatory Foods Cause Joint Pain?
Yes. Sugar may be hard to resist desserts, pastries, chocolate bars, sodas, even fruit juices. However, the American Journal of Clinical Nutrition warns that processed sugars trigger the release of inflammatory messengers called cytokines. Sugar goes by many names so look out for any word ending in “ose,” e.g. fructose or sucrose on ingredient labels. Pizza and cheese are the biggest sources of saturated fats in the average American diet, according to the National Cancer Institute. Other culprits include meat products (especially red meat), full-fat dairy products, pasta dishes and grain-based desserts. trans fat can be found in fast foods and other fried products, processed snack foods, frozen breakfast products, cookies, donuts, crackers and most stick margarines. Avoid foods with partially hydrogenated oils in the ingredient labels. o mega 6 fatty acids are an essential fatty acid that the body needs for normal growth and development. The body needs a healthy balance of omega-6 and omega-3 fatty acids. Excess consumption of omega-6s can trigger the body to produce pro-inflammatory chemicals. These fatty acids are found in oils such corn, safflower, sunflower, grapeseed, soy, peanut, and vegetable; mayonnaise; and many salad dressings. White flour products (breads, rolls, crackers) white rice, white potatoes (instant mashed potatoes, or french fries) and many cereals are refined carbohydrates. According to Scientific American, processed carbohydrates may trump fats as the main driver of escalating rates of obesity and other chronic conditions. These high-glycemic index foods fuel the production of advanced glycation end (AGE) products that stimulate inflammation. Mono-sodium glutamate (MSG) is a flavor-enhancing food additive most commonly found in prepared Asian Continue reading >>
- 14 Ways to Reduce Joint Pain With Diabetes
- Do Simvastatin Side Effects Include Diabetes and Joint Pain?
- Is it possible to catch diabetes? It sounds absurd, but that's what a reputable new study suggests. And it may be that other 'lifestyle' diseases such as joint pain and even obesity are contagious, too
Can Diabetes Kill You?
Here’s what you need to know about the life-threatening diabetes complication called diabetic ketoacidosis. Diabetic ketoacidosis is one of the most serious complications of diabetes. Symptoms can take you by surprise, coming on in just 24 hours or less. Without diabetic ketoacidosis treatment, you will fall into a coma and die. “Every minute that the person is not treated is [another] minute closer to death,” says Joel Zonszein, MD, professor of medicine at Albert Einstein College of Medicine in New York City. Diabetic ketoacidosis occurs when your body doesn’t produce enough insulin. (Diabetic ketoacidosis most often affects people with type 1 diabetes, but there is also type 2 diabetes ketoacidosis.) Without insulin, sugar can’t be stored in your cells to be used as energy and builds up in your blood instead. Your body has to go to a back-up energy system: fat. In the process of breaking down fat for energy, your body releases fatty acids and acids called ketones. Ketones are an alternative form of energy for the body, and just having them in your blood isn’t necessarily harmful. That’s called ketosis, and it can happen when you go on a low-carb diet or even after fasting overnight. “When I put people on a restricted diet, I can get an estimate of how vigorously they’re pursuing it by the presence of ketones in the urine,” says Gerald Bernstein, MD, an endocrinologist and coordinator of the Friedman Diabetes Program at Lenox Hill Hospital in New York City. RELATED: The Ketogenic Diet Might Be the Next Big Weight Loss Trend, But Should You Try It? But too many ketones are a problem. “In individuals with diabetes who have no or low insulin production, there is an overproduction of ketones, and the kidneys can’t get rid of them fast enough,” sa Continue reading >>
Joint Pain And Bone Conditions
Tweet Diabetes affects both the nerves and circulation which can result in joint pain and disorders developing in a number of areas of the body. In terms of the complications of diabetes, joint disorders tend to get mentioned less than the likes of retinopathy and kidney disease but some of the conditions can be serious. Charcot foot Charcot foot, also known as Charcot arthropathy and Charcot joint, is the name for a condition which causes the foot to swell and, in progressed cases, deform. Symptoms of Charcot foot include: Swelling or redness of joints in the foot Affected foot being warmer than the non-affected foot Pain in the affected area will be noticed Charcot foot can affect any of the weight bearing joints in the foot including the ankle. Charcot joint can be treated but the treatment takes time, up to several months, typically involving casting the foot and taking weight off it. Read more about Charcot foot Osteoporosis Osteoporosis, meaning porous bones, is a condition which causes bones to weaken. Areas which tend to be affected are the spine, wrist and hips. Symptoms develop slowly and can be hard to notice until an event causes a bone to break or fracture, termed as a ‘fragility fracture’. Treatment may include extra vitamin D and/or calcium in your diet and exercises to build up strength in the bones are often prescribed. Osteoarthritis Osteoarthritis includes inflammation of the tissues in the joints and damage to cartilage. People who are overweight put extra strain on their joints and can increase the risk of osteoarthritis as well as making the condition more pronounced. Osteoarthritis symptoms Symptoms include: Pain Stiffness A grating sound or a limited range of mobility in the joints. Osteoarthritis becomes more likely in old age, with 50 years Continue reading >>
- Is it possible to catch diabetes? It sounds absurd, but that's what a reputable new study suggests. And it may be that other 'lifestyle' diseases such as joint pain and even obesity are contagious, too
- Do Simvastatin Side Effects Include Diabetes and Joint Pain?
- 14 Ways to Reduce Joint Pain With Diabetes
Diabetic Ketoacidosis (dka)
Tweet Diabetic ketoacidosis (DKA) is a dangerous complication faced by people with diabetes which happens when the body starts running out of insulin. DKA is most commonly associated with type 1 diabetes, however, people with type 2 diabetes that produce very little of their own insulin may also be affected. Ketoacidosis is a serious short term complication which can result in coma or even death if it is not treated quickly. Read about Diabetes and Ketones What is diabetic ketoacidosis? DKA occurs when the body has insufficient insulin to allow enough glucose to enter cells, and so the body switches to burning fatty acids and producing acidic ketone bodies. A high level of ketone bodies in the blood can cause particularly severe illness. Symptoms of DKA Diabetic ketoacidosis may itself be the symptom of undiagnosed type 1 diabetes. Typical symptoms of diabetic ketoacidosis include: Vomiting Dehydration An unusual smell on the breath –sometimes compared to the smell of pear drops Deep laboured breathing (called kussmaul breathing) or hyperventilation Rapid heartbeat Confusion and disorientation Symptoms of diabetic ketoacidosis usually evolve over a 24 hour period if blood glucose levels become and remain too high (hyperglycemia). Causes and risk factors for diabetic ketoacidosis As noted above, DKA is caused by the body having too little insulin to allow cells to take in glucose for energy. This may happen for a number of reasons including: Having blood glucose levels consistently over 15 mmol/l Missing insulin injections If a fault has developed in your insulin pen or insulin pump As a result of illness or infections High or prolonged levels of stress Excessive alcohol consumption DKA may also occur prior to a diagnosis of type 1 diabetes. Ketoacidosis can occasional Continue reading >>
Does Humidity Cause Joint Pain?
This is an excellent question and one that does not have an easy answer. Many people with knee ostheoarthritis report increased pain with temperature or bad weather conditions (cold makes it worse, and stormy weather makes it worse). It's not a question of humidity but rather of barometric pressure. There is a 2007 study involving >200 with knee ostheoarthritis in the united States which participated in an online study reporting their pain daily, on a scale, for 3 months. Weather conditions were available for all participating locations. The participants did not know that weather was going to be one of the parameters they used in the study, to rule out that people reported more pain in relation to meteorologic conditions, because they are so convinced that's the case, that they will report it. Interestingly, the study showed that indeed, barometric pressure and temperature both affected pain severity in a statistically significant fashion in this group of people. Possible reasons are: 1) for stormy weather conditions, atmospheric pressure appears to play a role in the biomechanics of stabilizing the joint (typically divers report joint pain during compression), and 2) for cold weather, temperature can affect the viscosity of synovial fluid, and also there can be more inflammatory mediators in the joint space. Here's the link to the article: Changes in barometric pressure and ambient temperat... [Am J Med. 2007] Your daughter 1, you 0. Please promise me you'll tell her she won. Continue reading >>
- 14 Ways to Reduce Joint Pain With Diabetes
- Do Simvastatin Side Effects Include Diabetes and Joint Pain?
- Is it possible to catch diabetes? It sounds absurd, but that's what a reputable new study suggests. And it may be that other 'lifestyle' diseases such as joint pain and even obesity are contagious, too
Diabetic Ketoacidosis
Practice Essentials Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that mainly occurs in patients with type 1 diabetes, but it is not uncommon in some patients with type 2 diabetes. This condition is a complex disordered metabolic state characterized by hyperglycemia, ketoacidosis, and ketonuria. Signs and symptoms The most common early symptoms of DKA are the insidious increase in polydipsia and polyuria. The following are other signs and symptoms of DKA: Nausea and vomiting; may be associated with diffuse abdominal pain, decreased appetite, and anorexia History of failure to comply with insulin therapy or missed insulin injections due to vomiting or psychological reasons or history of mechanical failure of insulin infusion pump Altered consciousness (eg, mild disorientation, confusion); frank coma is uncommon but may occur when the condition is neglected or with severe dehydration/acidosis Signs and symptoms of DKA associated with possible intercurrent infection are as follows: See Clinical Presentation for more detail. Diagnosis On examination, general findings of DKA may include the following: Characteristic acetone (ketotic) breath odor In addition, evaluate patients for signs of possible intercurrent illnesses such as MI, UTI, pneumonia, and perinephric abscess. Search for signs of infection is mandatory in all cases. Testing Initial and repeat laboratory studies for patients with DKA include the following: Serum electrolyte levels (eg, potassium, sodium, chloride, magnesium, calcium, phosphorus) Note that high serum glucose levels may lead to dilutional hyponatremia; high triglyceride levels may lead to factitious low glucose levels; and high levels of ketone bodies may lead to factitious elevation of creatinine levels. Continue reading >>
Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a serious problem that can occur in people with diabetes if their body starts to run out of insulin. This causes harmful substances called ketones to build up in the body, which can be life-threatening if not spotted and treated quickly. DKA mainly affects people with type 1 diabetes, but can sometimes occur in people with type 2 diabetes. If you have diabetes, it's important to be aware of the risk and know what to do if DKA occurs. Symptoms of diabetic ketoacidosis Signs of DKA include: needing to pee more than usual being sick breath that smells fruity (like pear drop sweets or nail varnish) deep or fast breathing feeling very tired or sleepy passing out DKA can also cause high blood sugar (hyperglycaemia) and a high level of ketones in your blood or urine, which you can check for using home-testing kits. Symptoms usually develop over 24 hours, but can come on faster. Check your blood sugar and ketone levels Check your blood sugar level if you have symptoms of DKA. If your blood sugar is 11mmol/L or over and you have a blood or urine ketone testing kit, check your ketone level. If you do a blood ketone test: lower than 0.6mmol/L is a normal reading 0.6 to 1.5mmol/L means you're at a slightly increased risk of DKA and should test again in a couple of hours 1.6 to 2.9mmol/L means you're at an increased risk of DKA and should contact your diabetes team or GP as soon as possible 3mmol/L or over means you have a very high risk of DKA and should get medical help immediately If you do a urine ketone test, a result of more than 2+ means there's a high chance you have DKA. When to get medical help Go to your nearest accident and emergency (A&E) department straight away if you think you have DKA, especially if you have a high level of ketones in Continue reading >>
What You Should Know About Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a buildup of acids in your blood. It can happen when your blood sugar is too high for too long. It could be life-threatening, but it usually takes many hours to become that serious. You can treat it and prevent it, too. It usually happens because your body doesn't have enough insulin. Your cells can't use the sugar in your blood for energy, so they use fat for fuel instead. Burning fat makes acids called ketones and, if the process goes on for a while, they could build up in your blood. That excess can change the chemical balance of your blood and throw off your entire system. People with type 1 diabetes are at risk for ketoacidosis, since their bodies don't make any insulin. Your ketones can also go up when you miss a meal, you're sick or stressed, or you have an insulin reaction. DKA can happen to people with type 2 diabetes, but it's rare. If you have type 2, especially when you're older, you're more likely to have a condition with some similar symptoms called HHNS (hyperosmolar hyperglycemic nonketotic syndrome). It can lead to severe dehydration. Test your ketones when your blood sugar is over 240 mg/dL or you have symptoms of high blood sugar, such as dry mouth, feeling really thirsty, or peeing a lot. You can check your levels with a urine test strip. Some glucose meters measure ketones, too. Try to bring your blood sugar down, and check your ketones again in 30 minutes. Call your doctor or go to the emergency room right away if that doesn't work, if you have any of the symptoms below and your ketones aren't normal, or if you have more than one symptom. You've been throwing up for more than 2 hours. You feel queasy or your belly hurts. Your breath smells fruity. You're tired, confused, or woozy. You're having a hard time breathing. Continue reading >>
The Musculoskeletal Effects Of Diabetes Mellitus
Go to: Abstract Diabetes mellitus (DM) is a multi-system disease characterized by persistent hyperglycemia that has both acute and chronic biochemical and anatomical sequelae, with Type-2 DM representing the most common form of the disease. Neuromusculoskeletal sequelae of DM are common and the practicing chiropractor should be alert to these conditions, as some are manageable in a chiropractic office, while others are life and/or limb threatening. This paper reviews the effects of DM on the musculoskeletal system so as assist the chiropractor in making appropriate clinical decisions regarding therapy, understanding contraindications to therapy, referring patients to medical physicians when appropriate and understanding the impact that DM may have on the prognosis for their patients suffering from the myriad musculoskeletal conditions associated with this disease. Keywords: diabetes, musculoskeletal, chiropractic Go to: Introduction Diabetes mellitus (DM) is a multi-system disease characterized by persistent hyperglycemia that has both acute and chronic biochemical and anatomical sequelae. It is thought to affect almost 17 million Americans, only 11 million of whom have been diagnosed according to the American Diabetes Association. In type 1 diabetes, a lack of insulin results in poor carbohydrate, fat, and protein metabolism. Insulin is functionally absent, typically due to immune-mediated destruction of the beta cells of the pancreas, though other etiologies of beta cell destruction have also been implicated, including drugs, chemicals, viruses, mitochondrial gene defects, pancreatectomy and ionizing radiation.1 Type 1 DM (DM1) occurs most commonly in juveniles. It can occur in adults, especially in those in their late 30s and early 40s. Unlike people with Type 2 DM ( Continue reading >>
- The musculoskeletal effects of diabetes mellitus
- Women in India with Gestational Diabetes Mellitus Strategy (WINGS): Methodology and development of model of care for gestational diabetes mellitus (WINGS 4)
- Effects of Insulin Plus Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in Treating Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Diabetic Ketoacidosis Causes, Symptoms, Treatment, And Complications
Diabetic ketoacidosis definition and facts Diabetic ketoacidosis is a life-threatening complication of type 1 diabetes (though rare, it can occur in people with type 2 diabetes) that occurs when the body produces high levels of ketones due to lack of insulin. Diabetic ketoacidosis occurs when the body cannot produce enough insulin. The signs and symptoms of diabetic ketoacidosis include Risk factors for diabetic ketoacidosis are type 1 diabetes, and missing insulin doses frequently, or being exposed to a stressor requiring higher insulin doses (infection, etc). Diabetic ketoacidosis is diagnosed by an elevated blood sugar (glucose) level, elevated blood ketones and acidity of the blood (acidosis). The treatment for diabetic ketoacidosis is insulin, fluids and electrolyte therapy. Diabetic ketoacidosis can be prevented by taking insulin as prescribed and monitoring glucose and ketone levels. The prognosis for a person with diabetic ketoacidosis depends on the severity of the disease and the other underlying medical conditions. What is diabetic ketoacidosis? Diabetic ketoacidosis (DKA) is a severe and life-threatening complication of diabetes. Diabetic ketoacidosis occurs when the cells in our body do not receive the sugar (glucose) they need for energy. This happens while there is plenty of glucose in the bloodstream, but not enough insulin to help convert glucose for use in the cells. The body recognizes this and starts breaking down muscle and fat for energy. This breakdown produces ketones (also called fatty acids), which cause an imbalance in our electrolyte system leading to the ketoacidosis (a metabolic acidosis). The sugar that cannot be used because of the lack of insulin stays in the bloodstream (rather than going into the cell and provide energy). The kidneys f Continue reading >>
What Is The Most Important Information I Should Know About Glyxambi?
IMPORTANT SAFETY INFORMATION What is the most important information I should know about GLYXAMBI? Inflammation of the pancreas (pancreatitis), which may be severe and lead to death. Before you start taking GLYXAMBI, tell your doctor if you have ever had pancreatitis, gallstones, a history of alcoholism, or high triglyceride levels. Stop taking GLYXAMBI and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis. Heart failure. Heart failure means your heart does not pump blood well enough. Before you start taking GLYXAMBI, tell your doctor if you have ever had heart failure or have problems with your kidneys. Contact your doctor right away if you have any of the following symptoms: increasing shortness of breath or trouble breathing, especially when you lie down; swelling or fluid retention, especially in the feet, ankles or legs; an unusually fast increase in weight or unusual tiredness. These may be symptoms of heart failure. Dehydration. GLYXAMBI can cause some people to have dehydration (the loss of body water and salt). Dehydration may cause you to feel dizzy, faint, light-headed, or weak, especially when you stand up. You may be at higher risk of dehydration if you have low blood pressure, take medicines to lower your blood pressure, including water pills (diuretics), are on a low salt diet, have kidney problems, or are 65 years of age or older. Ketoacidosis (increased ketones in your blood or urine). Ketoacidosis is a serious condition, which may need to be treated in the hospital. Ketoacidosis may lead to death. Ketoacidosis occurs in people with type 1 diabetes and Continue reading >>
