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Can Dka Cause Lactic Acidosis?

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A Rare Case Of Persistent Lactic Acidosis In The Icu: Glycogenic Hepatopathy And Mauriac Syndrome

Copyright © 2016 Kirsten S. Deemer and George F. Alvarez. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Mauriac syndrome is a rare disorder that can present with the single feature of glycogenic hepatopathy in children and adults with poorly controlled diabetes mellitus. An often underrecognized finding of glycogenic hepatopathy is lactic acidosis and hyperlactatemia. Primary treatment of glycogenic hepatopathy is improved long-term blood glucose control. Resolution of symptoms and hepatomegaly will occur with improvement in hemoglobin A1C. We present here a case of a young adult female presenting to the intensive care unit with Mauriac syndrome. This case demonstrates exacerbation of lactic acidosis in a patient with glycogenic hepatopathy treated for diabetic ketoacidosis with high dose insulin and dextrose. 1. Introduction Lactic acidosis is a common finding in critically ill patients admitted to the intensive care unit (ICU) and it is associated with increased mortality [1, 2]. An anion gap and pH of l Continue reading >>

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  1. Wodkat

    So I've been on induction since last weekend and I've only tested with the ketostix today and it was very dark purple (Im hydrating though, I swear!). What I also noticed was a weird taste in my mouth. Kinda like blood? Which I've read is a sign of ketosis so that's normal.
    But I wanna confirm this: ever since yesterday, my pee is really smelly. Sorry for the tmi! But yeah I drink tons of water and it's still yellow and it stinks, but I've also noticed it's unusually foggy! Could that be cause by the ketones or should I be worried?

  2. moniruth

    I don't know what causes it but it happens to me too. Maybe fat cells being excreted? You have to get rid of all the stuff the body is breaking down. And yes, it really smells!

  3. Wodkat

    thanks, glad to know it's not just me, because I was worried it might be something else ! but since it started when it did I believe it might be due to ketosis. it only makes sense, the chemicals from lipolisis and the ketones should be able to cause it, and I even tested a VERY dark purple on the ketosticks so yeah, I think Im just gonna drink *even* more water now

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https://www.facebook.com/drinkhealthy... - Do you want to learn how to get rid of lactic acid as an athlete, and start recovering quicker with more energy? Learn how to reduce lactic acid symptoms and increase your performance. Getting rid of lactic acid may be easier than you have imagined. Many professional athletes know the importance of eliminating lactic acid so they can recover quicker and perform at an optimal level. Start flushing out that lactic acid today! Many people suffer from lactic acidosis symptoms and are rigorously searching for a lactic acid treatment. More and more athletes are searching for solutions on how to get rid of lactic acid. In this video you will learn what a professional football player from the Seattle Seahawks is using to eliminate lactic acid after his workouts, practices, and NFL games. Learn how to make lactic acid a symptom of the past. Begin your journey to faster recovery today. See what the pro's are using to reduce lactic acid, recover quicker, and have more energy. Uncertain of what lactic is? Here is the definition https://en.wikipedia.org/wiki/Lactic_... Contact me for more information on getting rid of lactic acid FB: http://www.faceboo

Lactic Acidosis

Background In basic terms, lactic acid is the normal endpoint of the anaerobic breakdown of glucose in the tissues. The lactate exits the cells and is transported to the liver, where it is oxidized back to pyruvate and ultimately converted to glucose via the Cori cycle. In the setting of decreased tissue oxygenation, lactic acid is produced as the anaerobic cycle is utilized for energy production. With a persistent oxygen debt and overwhelming of the body's buffering abilities (whether from chronic dysfunction or excessive production), lactic acidosis ensues. [1, 2] (See Etiology.) Lactic acid exists in 2 optical isomeric forms, L-lactate and D-lactate. L-lactate is the most commonly measured level, as it is the only form produced in human metabolism. Its excess represents increased anaerobic metabolism due to tissue hypoperfusion. (See Workup.) D-lactate is a byproduct of bacterial metabolism and may accumulate in patients with short-gut syndrome or in those with a history of gastric bypass or small-bowel resection. [3] By the turn of the 20th century, many physicians recognized that patients who are critically ill could exhibit metabolic acidosis unaccompanied by elevation of ket Continue reading >>

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  1. Daniel Nebdal

    Programming Computer Applications

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    What are ketostix? What are they used for?




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    They’re small measuring sticks that you pee on. They measure the amount of ketones, a family of energy-carrying molecules you get when burning fat.
    Ketones can indicate good and bad things - if you intentionally diet and exercise to burn fat you may want to see an increased amount. The safety of this is debated, but it seems to be harmless in moderation?
    If you have diabetes and don’t get/produce enough insulin, it can indicate that you are heading into diabetic ketoacidosis - where your blood contains far too much glucose and your body is also burning fat giving you far too much ketones. This can be quite dangerous - overly acidic blood is not great for you.

    Wikipedia has a reasonable summary: Ketosis

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Lactic Acidosis In Diabetic Ketoacidosis

Go to: Discussion Lactate acidosis is a common finding in DKA. Several pathophysiological mechanisms are responsible for the extremely high lactate values sometimes found in patients with ketoacidotic. Originally, elevated lactate values in patients with DKA were thought to be the result of inadequate tissue perfusion and oxygenation (due to a contracted intravascular volume, aggravated by the presence of macrovascular disease and microangiopathies, an increased amount of glycosylated Hb, and an abnormal platelet function).1–3 The resulting relative hypoxaemia stimulates the process of anaerobic glycolysis, where pyruvic acid is converted to l-lactate, yielding two ATP molecules. More recently, however, it was demonstrated that the metabolic derangements itself present in DKA might contribute as well to the elevated lactate levels.4 Various studies have reported the presence of a positive correlation between glucose levels and ketone (β-hydroxybutyrate) levels on the one hand, and lactate levels on the other hand.4 5 This could be explained by various intracellular and extracellular mechanisms. First, an increased amount of d-lactate is formed in erythrocytes. Since erythrocytes Continue reading >>

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  1. Doominatorx

    Beer on keto?

    i know in general its a no no, and i intend to drink just this once, so how many 12 oz cans could i get away with of a light beer, without knocking my body out of keto?

  2. asudin

    Depends of the beer (carbs?). The carbs are what will throw you out of keto, not the alcohol. However, the consumption of alcohol calories (7cal/g) will take higher priority to burning fat so it will "post-pone" your fat burning.
    lol @ "Age: 18" in your info, Doominatorx

  3. blinkers88

    you should really just avoid it

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