diabetestalk.net

Best Ketone Supplements

Ketone Bodies And Performance

Ketone Bodies And Performance

Even for the average fitness enthusiast, the term ketone or ketone body may not mean much. There are some who associate it with the highly popularised “ketogenic diet” (also called Atkins diet), while some science graduates may recall it being mentioned in their biochemistry classes. Traditionally thought of as a toxic by-product of fat oxidation, ketone bodies are rapidly being seen in a more favourable light within the health and fitness industry as new therapeutic roles are found for them in health, disease and even exercise performance. This article will provide a brief overview of what ketone bodies are, how they are generated and their therapeutic potential for health and disease. What Are Ketone Bodies? Strictly speaking, ketone bodies encompass three compounds, namely, acetoacetate, b-hydroxybutyrate and acetone, with the major circulating form being beta-hydroxybutyrate1. Ketone bodies are generated under conditions of limited carbohydrate availability, such as fasting or low carbohydrate diets1. In such instances, the body’s stores of carbohydrates are depleted and the body is forced to increase its use of fatty acids to make up the energy deficit from depleted glucose stores (i.e. glycogen). Whenever the body significantly accelerates its use of fatty acids, it starts to generate ketone bodies, which are essentially a by-product of fatty acid oxidation. This process of making ketone bodies (i.e. ketogenesis) occurs primarily in the liver. Physiological vs Pathological Ketosis Ketogenesis was originally thought to be a ‘back-up’ energy system used by the body to fuel key organs such as the heart and brain during times of food restriction or starvation. However, in today’s western world where hunger and poverty are not major problems, individuals ar Continue reading >>

Avoid This Ketogenic Rip-off

Avoid This Ketogenic Rip-off

The Truth About Exogenous Ketones Ketones are all the rage among low carbers. And like most things in nutrition and performance, we've found a way to get them in supplement form so we don't have to do any actual work. What are ketones? They're a byproduct of ketosis caused by the process of converting fat to fuel. Your body makes them when it's in a calorie or carb restricted state. What do they do? The body and brain can use them as fuel without the presence of glucose in the blood. And now, you can take ketone supplements (salts and esters), known as exogenous ketones, without actually restricting anything. According to those promoting this nasty-tasting supplement, that means you can have a brain and body fuelled by ketones, along with all of the supposed health benefits that come with running on fat. Well, don't fall for it. Exogenous Ketones = Endogenous Fat Storage? The problem with ketone supplementation (EXOgenous) is that it's not even close to the same thing as being in ketosis (ENDOgenous ketone production). And just like the butter-blended-into-coffee trend, it's a farce. Ketones may be depressing dieters' hunger and giving them a hit of energy and cognitive enhancement, but it's INHIBITING their ability to burn fat, providing zero nourishment, and doing nothing for their metabolic health. There's an assortment of evidence suggesting that it's probably making things worse. Think of exogenous ketones kind of like alcohol. When they're consumed, everything is stored and nothing else is burned. So any lipolysis (fat burning) that would be taking place is halted; any glucose and fatty acids in your blood that were circulating are stored; and the ingested ketones are burned until there aren't any left. More importantly, this clearance of alternative fuels (glucos Continue reading >>

What Everybody Ought To Know About Ketosis

What Everybody Ought To Know About Ketosis

Recently I wanted to explore the world of Ketosis. I thought I knew a little bit about ketosis, but after doing some research I soon realised how wrong I was. 3 months later, after reading numerous books, listening to countless podcasts and experimenting with various diets I know have a sound understanding of ketosis. This resource is built as a reference guide for those looking to explore the fascinating world of ketosis. It is a resource that I wish I had 3 months ago. As you will soon see, a lot of the content below is not mine, instead I have linked to referenced to experts who have a greater understanding of this topic than I ever will. I hope this helps and if there is something that I have missed please leave a comment below so that I can update this. Also, as this is a rather long document, I have split it into various sections. You can click the headline below to be sent straight to the section that interests you. For those that are really time poor I have created a useful ketosis cheat sheet guide. This guide covers all the essential information you should know about ketosis. It can be downloaded HERE. Alternatively, if you're looking for a natural and sustainable way to improve health and lose weight head to this page - What is Ketosis? What Are The Benefits from being in Ketosis? Isn’t Ketosis Dangerous? Ketoacidosis vs Ketosis What Is The Difference Between a Low Carb Diet and a Ketogenic Diet? Types of Ketosis: The Difference Between Nutritional, Therapeutic & MCT Ketogenic Diets Is The Ketogenic Diet Safe? Long Term Effects Thyroid and Ketosis - What You May Want To Know What is a Typical Diet/Macro Breakdown for a Ketogenic Diet? Do I Need to Eat Carbs? What do I Eat On a Ketogenic Diet? What Do I Avoid Eating on a Ketogenic Diet? Protein Consumption a Continue reading >>

What Are The Best Keto Supplements In 2017?

What Are The Best Keto Supplements In 2017?

A popular diet that is largely entering the weight loss industry is the keto diet. But many people are wondering, what is it? Well the science behind such a weight loss plan revolves around a chemical process in the body called ketosis. This is a process that occurs when the body has a shortage of glucose in the body that it needs to burn for fuel. When the body is low on energy, and has no sugar to burn, it relies on other sources of energy to burn: in this case, fat. Ketones – The Supplement Of Choice Ketones are the biproducts of the chemical reaction of ketosis, where the body burns fat to gain energy for the brain and body. Namely, they’re the body’s alternative energy source to glucose. However, it’s important to consider eating very specific foods when using a ketogenic diet. Here are a few good food sources to pursue this sort of diet: Naturally occurring fats (i.e. butter, olive oil, etc.) Meats (Pork, Beef, Etc.) Fish and seafood (Cod, Flounder, Halibut, Dairy (Eggs, milk, cheese, etc.) Nuts and seeds (Peanuts, almonds, cashews, etc.) Drink mostly water, and stay away from sweeteners A ketogenic diet consists mostly of complex fats, while staying away from carbs and proteins to help the body, the biproducts of ketosis. When these biproducts occur naturally in the body, they are considered endogenous. When they occur as the result of an external supplement, they are considered exogenous. Today we’re going to talk about the most popular exogenous supplements on the keto diet market. What are Exogenous Ketones? These supplements often come in the form of keto drinks, powders and energy bars. Exogenous supplements provide an instantaneous way to get ketones in the body. They increase bloodstream ketones even if your body is not undergoing ketosis. As-a-r Continue reading >>

Raspberry Ketone

Raspberry Ketone

Summary All Essential Benefits/Effects/Facts & Information Raspberry ketone is the compound responsible for many flavoring and aromatic qualities of cosmetics and processed foods. When present in high doses, raspberry ketone can exert fat burning effects on various areas of the fat cell. These effects may be similar to those of ephedrine and synephrine. It should be noted that all evidence for the effects of raspberry ketone has only been observed in vitro (in a test tube). Though researchers are able to raise the concentrations of ketones in a single cell during studies, these same concentrations cannot be replicated in the human body, particularly through oral supplementation. Things to Know 4-(4-hydroxyphenyl) butan-2-one, p-hydroxybenzyl acetone Raspberry ketone is said to be non-stimulatory, but this has not been properly addressed by research Raspberry ketone has a slightly artificial raspberry aroma and taste How to Take Recommended dosage, active amounts, other details There is no human evidence for the effects of raspberry ketones. Studies on rats have used a dosage range of .545-2.18g/kg, which correlates to a human estimated dose of 80-340mg/kg for humans. This dose is very high compared to other fat burning compounds, so for that reason the standard supplemental dose of raspberry ketones for humans is in the 100-200mg range. There is no solid evidence for the effectiveness of the doses listed below. Rat dosages correlate to the following human doses: 870-3,700mg for a 150lb person 1,100-5,000mg for a 200lb person 1,500-6,200mg for a 250lb person There is no human evidence for the effectiveness of raspberry ketones. Raspberry ketones cannot be concentrated in the human body the same way they are concentrated during studies done outside the body, on single cel Continue reading >>

Pruvit Keto-os – The Ketone Operating System

Pruvit Keto-os – The Ketone Operating System

Pruvit is a trusted health and wellness company with highly known ketone supplements and nutritional products. Their most popular formula is Keto-OS, which stands for Ketone Operating System and it’s a powdered weight-loss ketone drink. The company describes Keto-OS as a powder that you mix with 8-10 oz. of water and within 15-30 minutes it puts the body in a state of Ketosis. Exogenous Ketone supplements are commonly used for weight loss and to enhance physical performance because of their unique properties. When the body lacks glucose, sugars and starchy foods for energy, it burns stored fats instead; this creates a beneficial build-up of acids within the body called ketones. According to multiple studies the benefits of ketones ranges from weight loss, to athletic performance, appetite control and other positive side effects that come from getting the body in a state of Ketosis. When we contacted Pruvit for a quote about their supplements and what they do, here is what they said: Keto-OS is your “ketone operating system” it’is the First Therapeutic Ketone Supplement on the market. The proprietary blend is owned by Prüvit and is Dr. Approved, Lab Tested, University backed and the technology in Keto-OS is patent pending, developed by one of the most world renown Dr.’s and experts on Ketosis. Prüvit was the first company approved by University of South Florida to acquire the sub-license rights to use this patent pending technology. Keto-OS is a powder that you mix with 8=10 oz. of water. Within 15-30 minutes it puts your body into Ketosis. Keto-OS. Keto-OS has a certificate of analysis for purity, consistence and efficacy. Over the past 5 years, Keto-OS has solidified itself as one of the most well known and used ketone supplements. We asked Pruvit why someo Continue reading >>

Ketone Ester Review: What Are They, And Do They Work?

Ketone Ester Review: What Are They, And Do They Work?

It's an exciting day at the KetoConnect household! We finally got our hands on the first commercially available ketone ester! The only company currently making this stuff is KetoneAid and they were nice enough to send us a sample to try for ourselves. We have tried most of the exogenous ketone supplements on the market and have not been impressed, but this is something completely different. Exogenous Ketones - Salts VS Esters The difference is night and day. When supplementing with the current BHB Salts on the market the impact is negligible. Often I will feel absolutely nothing, where other times I will notice a small benefit in energy and focus. It turns out this is due to the small dose that all BHB Salts deliver. There is an upper limit to how much you can consume at a given time because the ketones are binded to a salt such as sodium, potassium or magnesium. Ketone Esters on the other hand have no limit. You can consume exponentially more at a given time, which leads to a dramatic increase in benefits. The difference is rather astonishing and has completely reversed my thoughts on supplementing ketones and the future of the ketone supplement market. The Taste - Yes...It's That Bad! While the taste is much improved from the original iteration of these ketone esters, it's still pretty terrible. I'd describe it as a mix between rubbing alcohol and what I imagine toilet cleaner would taste like, with a squeeze of lemon. I'm sure this will continue to improve over time, and while it is terrible I don't feel it makes the supplement too prohibitive. It's easy to justify a few minutes of discomfort for hours of increased productivity. We Monitored Our Ketone and Glucose Levels After choking down our respective drinks, we started monitoring our blood ketone and glucose leve Continue reading >>

Ketone Supplements Extend Lifespan

Ketone Supplements Extend Lifespan

Very Low Carbohydrate Ketogenic Diets Eating a very low-carbohydrate diet results in the production of ketones, which the body uses as an alternative fuel source; hence very low-carbohydrate diets (VLCKD) diets are called ketogenic. The liver makes ketones from fatty acids when glycogen (the storage form of carbohydrate) has been depleted, hence going without carbohydrates, or fasting altogether (for around 16 hours or more), ramps up ketone production, and it does this to spare glucose so that the brain can use it. While it’s been known for a long time that ketogenic diets have therapeutic uses, such as for weight loss and in epilepsy, new research is showing the relation between ketones, longevity, and cancer. Ketone supplements extend lifespan The ketones, often referred to as ketone bodies, are beta hydroxybutyrate (BHB), acetoacetate, and acetone. Ketogenic diets are therapeutic for several reasons, one of the most important being a decrease in levels of the hormone insulin. Low insulin allows fat to be released from fat (adipose) tissue, hence a ketogenic diet speeds weight loss. One of the main benefits of ketogenic diets may be the production of ketone bodies themselves. Ketones mimic many of the changes that calorie restriction causes, and ketones have been found to extend lifespan in C. elegans. Scientists believe ketones should also extend human lifespan. Calorie restriction works via ketones Calorie restriction as a method of extending lifespan in animals has been known or a long time, maybe 80 years or so, but the concept goes back much further. Luigi Cornaro (1464-1566) sought the advice of physicians when he was in his 30s (placing the time at about 1500) when he was so sick that he felt he was going to die; Cornaro may have been diabetic. One of the do Continue reading >>

Breakthrough New Ketone Supplement!

Breakthrough New Ketone Supplement!

A Breakthrough New Ketone Supplement For the last two years I have been living and breathing everything keto, and also reading every book and research out there about ketosis and the benefits of keto adaptation. I have also assisted many conferences, and it was last year at AHS14 that I met Dr. DiAgostino. Dr. DiAgostino is one of the leading researches working with cancer and ketosis at the University of South Florida. Is also one of the first researchers to study the effects of exogenous ketone supplementation. He is the first person who talked to me about ketone supplements, and he really spiked my curiosity, mentioning all the amazing benefits of supplementing with BHB. Here is a great article that explains more about his work. So I decided to try a ketone supplement on myself. Unfortunately what was on the market a year ago was a very unpalatable pure ketone salt (KetoForce), which worked on elevating my ketosis but also gave me very bad stomach upset and nausea. Needless to say I did not continue taking it, and forgot all about ketone supplements. A quick look at ketones and how they work. As you might already know ketones are metabolites with cellular structure quite similar to glucose and they are produced in the liver out of fatty acids, in order to feed the body with energy, when glucose is low or absent. That is why ketosis is induced by restricting carbs and not by adding fat to your diet!! Unfortunately not every body is equally able to convert fat into ketones or getting in ketosis would be much easier! In my clinical experience I learned that every time your liver is not functioning perfectly or is congested, you will have a harder time producing those desired ketones and keeping a high level of nutritional ketosis. That is why weight loss stalls and you Continue reading >>

Ketones To Combat Alzheimer’s Disease

Ketones To Combat Alzheimer’s Disease

Despite decades of efforts to develop a drug that prevents or cures Alzheimer’s disease (AD), the most prevalent form of dementia afflicting our aging population, there is currently no treatment for this devastating condition. Emerging research suggests that such a miracle treatment might already exist, not in the form of a pill, but as a simple dietary change. A growing number of studies report that interventions to improve metabolic health can alleviate symptoms and reduce brain pathology associated with AD. A popular theory posits that AD has multiple causes, but their common thread may involve metabolic dysfunction. Indeed, markers of poor metabolic health, such as diabetes, inflammation and high cholesterol, are major risk factors for AD. Just like our muscles, the brain requires energy to function properly. Both neurons and muscles have the unique capacity to metabolize ketones as an alternative fuel source when glucose is in short supply, for instance during fasting or on a low-carbohydrate diet. In the 1920s scientists discovered that a high fat diet promoting ketogenesis controlled epilepsy, and ketosis remains one of the most effective treatments for the condition. This raised the possibility that ketones may also be neuroprotective against other diseases that stem from aberrant neural metabolism, such as AD. Since then, research has confirmed that ketones do in fact alter brain metabolism in ways that reduce neuropathology and relieve behavioral symptoms. Ketones alleviate symptoms of Alzheimer’s disease Over the past decade, several studies have supported the clinical value of ketosis in cognitively impaired patients. In a 2004 study twenty individuals with AD or Mild Cognitive Impairment (MCI) were treated with placebo or medium chain triglycerides, a t Continue reading >>

Which Ketone Supplement Works Best: Ketone Salts Vs. Ketone Esters With Dr. Dominic D’agostino

Which Ketone Supplement Works Best: Ketone Salts Vs. Ketone Esters With Dr. Dominic D’agostino

1. Podcast from: esters/ [3:19] Introduction [7:02] About Dr. Dominic D’Agostino [9:25] The Difference Between Ketone Esters and Ketone Salts [18:08] How Do They Commercialize the Ketones From Their Labs? [23:55&25:00&27:01] Three Unique Compounds and Others You Can “mix” with Ketones [29:00] What Occurs on a Physiological Level That Would Allow the Consumption of Branched Chain Amino Acids to Maintain Ketosis or Elevate It? [37:44] Sun in your Pocket – The Human Charger [39:17] Four Sigmatic [41:07] Why Some People Including Dr. Veech Believe Ketone Esters to be Dangerous and That MCT Oil Blocks Beta-Hydroxybutyrate Absorption or Utilization [47:50] Are There Any Evidence of People Experiencing Medical Issues with Using Ketone Salts or Esters? [60:05] Why Ephedrine Can Be Safely Used for Fat Loss and Dom’s Own Experience With It [65:40 & 1:05:41] Can You Combine Glucose with Ketones to Enhance Performance? [72:15] Why Esters are More Expensive Than Salts? Are There Ways to Make Either More Cost Effective? [1:12:14] Why are Ketone Esters More Expensive Than Ketone Salts? [1:28:40] End of Podcast Ben: Hey, you smart cookie, it’s Ben Greenfield. You better be a smart cookie because we put our propeller hats on in today’s episode with Dominic D’Agostino we get into ketosis. And speaking of ketosis as a nutritional therapy, I’m headed down to Vancouver in March and you should join me. March 3rd through the 5th. I’m speaking at this thing called the NTA Conference. In this episode of the Ben Greenfield Fitness Show: 2. "We understood ketones as an energy metabolite but it would make sense that these energy metabolites even the Kreb Cycle intermediates, the energy metabolites are powerful signaling modules. The receptors and pathways in our body, in our ce Continue reading >>

3 Reasons Keto//os Is The Highest Quality Ketone Supplement

3 Reasons Keto//os Is The Highest Quality Ketone Supplement

With the popularity of the keto diet on the rise, various ketone supplements are popping up around the globe. What is it exactly that makes a quality ketone supplement? This is a common question that people are asking. The high amount of new ketone products on the market can make the decision process difficult as to which one to buy. Not all ketones are created equally. We here at Keto Elevated recommend KETO//OS as the best ketone supplement out on the market. And to help you decide, here are 3 reasons that set Pruvit’s KETO//OS apart from other ketone supplements: 1. The type of isomer that is contained in the ketone supplement. When it comes to exogenous ketones there are two different types of isomers. There are d-isomers, and l-isomers. Many of the other ketone supplements out on the market are using a mixture of these D and L isomers. What the scientific literature for the past several decades has shown is that the d-Isomer is the most active isomer. It’s the isomer that this the most active component in creating ketone responses that get results. The l-isomer on the other hand, is kind of a nerf. It doesn’t really do much, and there is not much to it. So the issue here, is that these other supplement companies out there that are using a D/L isomer combination for their ketone salts are really giving you a half-baked product. Studies have also shown that the l-isomer can actually inhibit some the the good d-isomer’s active processes. In light of that, ketone products containing the l-isomers can be giving you less than half the benefits you’d get with a d-isomer focused product like KETO//OS. 2. The process in which the ketone supplement is made. The manufacturing process and how the ketones are made can have a profound effect on the quality of the keton Continue reading >>

How Can You Avoid Bad Raspberry Ketone Products

How Can You Avoid Bad Raspberry Ketone Products

"Raspberry Ketone Premium™ is the best raspberry ketone product out there. It was the only supplement to actually work for me and shift the fat!"* - Jenny T. 100% Pure - 500mgs All Natural Raspberry Ketone with No Fillers, Binders or Extra Ingredients 100% All Natural Raspberry Ketones Raspberry Ketone Premium™ was created to meet the growing demands of consumers for a high quality, premium raspberry ketone supplement at the best price possible. It is the strongest, most potent raspberry ketone product on the market hands down.* Read about the famous clinical Study done on Raspberry Ketones.* We're so confident that Raspberry Ketone Premium™ will work for you that we are offering a 90 day Money Back Guarantee! So, feel confident that you will lose weight, or your money back!* ...And Choose One That Will Actually Work? "Not All Raspberry Ketones Are Created Equal." Before you buy a Raspberry Ketone product, it's important you know what you're buying. Many supplement makers are rushing to create their own product and "cash-in" on this huge diet craze. Beware, many of the supplements out there claim to have the best product, but most of them either don't have enough raspberry ketones to be effective or use synthetically grown ketones. And more importantly, most supplements do not use the same source found effective in clinical studies. Weight loss* results with raspberry ketones are mainly dependent on the quality of the raspberry ketone extract you buy. So before you buy, make sure the raspberry ketone extract you choose meets all the criteria. Why Is Raspberry Ketone the Hottest Diet Today? Raspberry Ketone became popular when the most famous doctor on TV called it "the #1 miracle in a bottle to burn your fat" on his popular TV talk show. It's now the biggest diet Continue reading >>

My Experience With Exogenous Ketones

My Experience With Exogenous Ketones

Last year I wrote a couple of posts on the nuances and complexities of ketosis, with an emphasis on nutritional ketosis (but some discussion of other states of ketosis—starvation ketosis and diabetic ketoacidosis, or DKA). To understand this post, you’ll want to at least be familiar with the ideas in those posts, which can be found here and here. In the second of these posts I discuss the Delta G implications of the body using ketones (specifically, beta-hydroxybutyrate, or BHB, and acetoacetate, or AcAc) for ATP generation, instead of glucose and free fatty acid (FFA). At the time I wrote that post I was particularly (read: personally) interested in the Delta G arbitrage. Stated simply, per unit of carbon, utilization of BHB offers more ATP for the same amount of oxygen consumption (as corollary, generation of the same amount of ATP requires less oxygen consumption, when compared to glucose or FFA). I also concluded that post by discussing the possibility of testing this (theoretical) idea in a real person, with the help of exogenous (i.e., synthetic) ketones. I have seen this effect in (unpublished) data in world class athletes not on a ketogenic diet who have supplemented with exogenous ketones (more on that, below). Case after case showed a small, but significant increase in sub-threshold performance (as an example, efforts longer than about 4 minutes all-out). So I decided to find out for myself if ketones could, indeed, offer up the same amount of usable energy with less oxygen consumption. Some housekeeping issues before getting into it. This is a self-experiment, not real “data”—“N of 1” stuff is suggestive, but it prevents the use of nifty little things likes error bars and p-values. Please don’t over interpret these results. My reason for shari Continue reading >>

The Perks Of Fasting, With None Of The Work

The Perks Of Fasting, With None Of The Work

“If there’s a downside, it is kind of crazy tasting,” said Geoff Woo, the founder of HVMN, a Silicon Valley company that makes nootropics, or performance-enhancing supplements. We were in a conference room in The Atlantic’s office building, and he was bracing me for my trial run of his latest product. It was a small, clear vial labeled “Ketone,” a new type of energy drink his company is releasing this week. Its nutrition label says it contains 120 calories, but no carbs, no fat, and no protein. Instead, it’s all ketones, the chemical that Woo and his company are calling a “fourth food group.” He hopes the drink will allow people to reap the benefits of occasional fasting—high ketone levels inside the body—without actually having to not eat. I unscrewed the top and, college-days muscle memory kicking in, chugged it like a shot of Captain Morgan. It tasted like cough syrup that had been poured into a garbage bag and left in the sun. “Augh!” I cried. “I compare it to a combination of a liquor shot with nail-polish remover,” Woo said. Woo’s coworker, Brianna Stubbs, went to fetch me a glass of water. “We’ve done a lot of work to make it better,” she said. Within an hour, the drink was supposed to help improve my athletic performance by changing how my body burned energy during exercise. Some people also say it helps them feel more energetic and focused on their work. About 25 minutes after I drank Ketone, Woo and Stubbs pricked my finger to see if it was working. My blood sugar, which had verged on diabetic levels from some pineapple I had eaten that morning, was down to near-normal levels. Meanwhile, my ketones, which had been practically nonexistent before imbibing—measuring just 0.2 millimolar—had soared to 4.9. “It would have Continue reading >>

More in ketosis