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Bears Hibernation Ketosis

Does Quitting Carbs Cause Thyroid Issues?

Does Quitting Carbs Cause Thyroid Issues?

Alright, this is a controversial one. Anything Paleo-orientated generally is. But let’s wade in. I have a number of reasons for distancing myself from the Paleo movement. I agree with many of the dietary principles inherent, just not the faddishness, the fanaticism and the insistence on basing it on a meta-theory of how we ate 10,000 years ago. I’m also cautious about the whole low/no-carb fervour in general. It’s not for everyone. Like, for instance, anyone trying to get pregnant. But today I want to raise this one: cutting carbs might just trigger thyroid problems. Strap in. I recently came across American biochemistry and genetics expert, Dr. Cate, and have asked her to flesh things out… People who run into trouble going low-carb seem to follow a pattern. First, they (make) a relatively abrupt switch to low carb (often less than 50 gm). Initially they lose weight as hoped but then, instead of feeling more energetic from their weight loss, they develop fatigue, sometimes accompanied by symptoms of low thyroid function including cold extremities, hair loss, and digestive problems. Because their fatigue and other symptoms are classic for thyroid malfunction, many will get their levels tested, only to come away confused when the tests health practitioners typically order (TSH and T4) come out normal. Those who get more extensive testing may get a test called reverse T3, or rT3 for short. These are often abnormally high, leaving them to believe they have found the root of the problem. Some are given a prescription for T3 (or thyroxin) in hopes of regaining energy and the intervention seems to help, at least a little. Reverse T3 is a kind of chemical opposite of regular T3, a mirror image compound called an enantiomer. Reverse T3 has opposite effects of T3, and has Continue reading >>

Best Ketogenic Diet Book For Cancer

Best Ketogenic Diet Book For Cancer

The best Ketogenic Diet Book for Cancer will be available to the public soon. I’m currently completing what will be once published the best ketogenic diet book for cancer available on the market. This book will be a raw vegan ketogenic diet book which comes from decades of firsthand experience helping people heal from cancer. I’m asked often if this vegan keto diet is science based? The answer is yes, it is backed by science big time! My book will be drawn from years of helping people restore their health and go on to thrive. We use this healing diet at An Oasis of Healing, the healing center I founded over a decade ago. A raw vegan ketogenic diet works in harmony with our comprehensive cancer care program. Raw plant based nutrition is key to healing from cancer and works in harmony with the laws of nature. Let’s look at what the word Keto means? Keto also means ketosis or ketones. What is the function of ketosis? Fatty acids allow human beings to store energy. As these fatty acids are separated into different pieces they become fuel for the body. When they are separated even further, they become ketone bodies which consist of three molecules. The ketone bodies are carried into cells and then split apart even more to become pure fuel for the body. This fuel provides the necessary energy for the body. These fatty acids produce twice the amount of energy versus carbs and protein. Fat is nature’s gift to humanity as a result of its capacity for energy storage. Why do you think bears are able to hibernate all winter? They eat a lot and as a result store fat. They then go into hibernation and live off their stored fat. While they hibernate, the bears are in ketosis. The Best Ketogenic Diet Book For Cancer Can Help Reverse This Pandemic There’s a right way and a wro Continue reading >>

Do Hibernating Bears Urinate?

Do Hibernating Bears Urinate?

And now for a discussion of a burning nephrology question: what happens to a bear's renal function when it goes into hibernation? (Thank my brother for raising the question while he was a medical student.) The simple answer to the headline question is: no, they do not. The details behind what does happen to renal function and nitrogenous waste disposal in hibernating bears is unfortunately not fully worked out yet, but what is known is a fascinating example of adaptive physiology. Bears hibernate in spans of a few weeks to several months, depending on the species, the weather, and available food stores. During that period, their metabolism drops to about a third of normal. There is a shift away from protein and carbohydrate metabolism toward fat breakdown. These processes result in a few notable changes in renal function: creatinine rises (from an average of 1-1.5 mg/dL to 3 mg/dL, thought to be due to decreased renal perfusion), and urea:creatinine ratio falls (as a result of decreased protein metabolism). A small amount of urine, about 100 mL, is produced, and the water and nitrogenous breakdown products are reabsorbed through the bladder. How does this happen? No idea. Urea is degraded, again by an unknown mechanism: one theory is that urease-producing bacteria in the gut aid in breakdown. Nitrogen is also thought to be shunted toward protein anabolism. The amazing result is that blood from hibernating bears does not contain an elevated level of urea, uric acid, amino acids, or ammonia. They replenish the water lost via respiration via lipolysis, where water is an end product. Interestingly, despite increased fat metabolism, bears do not develop a ketosis. Again, not sure why (may be related to increased glycerol metabolism). So, next time you see a bear foraging thr Continue reading >>

Slim By Summer, Secrets Of Ketosis

Slim By Summer, Secrets Of Ketosis

30day Fat Burning Diet Program: Lose Weight, Secrets of Ketosis Listen to the sweet sounds. The birds are singing. The lawn mower motors are rumbling. Children are outside playing and squealing with delight. Are you smiling? Maybe not. You may just feel stressed because you added pounds like a hibernating bear over the winter and these changes mean it’s time for shorts and halter tops. 30day Physician-Designed Fat Burning Diet Program Fear not. Take action now. You can lose more than 10 pounds in 30 days with an effective (& healthy) combination of high fiber, lean protein and healthy carbs. You can follow this diet without counting calories, counting carbs or counting points. It’s heart-healthy, diabetic-friendly and easy. 30day Diet Program – Phase One Here’s the scoop on this 3-step 30day physician-designed fat burning diet program. The first phase will jump-start your weight loss. You should lose 8-13 pounds over the first two weeks. Most of what you shed will be from your mid-section. During this time, your blood sugar levels will stabilize and you will eliminate your cravings for sugary foods and refined starches. You will do this with a good balance of nutrient-dense naked foods. These naked foods are foods that are unprocessed, foods in their natural state, free from additives. These naked foods include healthy carbs, lean protein and healthy fats because your body needs all three of these nutrients to thrive. The plan determines what carbs are healthy using the glycemic index and glycemic load index. Healthy fats include monounsaturated fats such as in olive oil and almonds. Lean proteins include lean cuts of meats and low fat cheeses. 30day Diet Program – Phase Two You can move on to the second phase of the 30day fat burning diet program after comple Continue reading >>

#200: Ben Bikman, Phd: Brown Fat Tissue Activation, Insulin & The Ketogenic Diet

#200: Ben Bikman, Phd: Brown Fat Tissue Activation, Insulin & The Ketogenic Diet

Want Early Access to Our Interviews and Additional Content? Become a High Intensity Health Insider and Access Bonus Content Listen to the recording What Others Are Saying About This Episode About Ben Bikman, PhD The focus of Ben's lab (the Laboratory of Obesity and Metabolism) is twofold. First, we aim to identify the molecular mechanisms that explain the increased risk of disease that accompanies weight gain, with particular emphasis on the etiology of insulin resistance and disrupted mitochondrial function. Second, we hope to reveal novel cellular processes that are responsible for fat development. Connect with Ben FaceBook Benjamin Bikman Instagram & Twitter @benbikmanphd Products Mentioned In this Episode Not Getting Results on the Ketogenic Diet? Need Meal Plans and Recipe Ideas? Access our Real-Food Recipe eBooks, Private FB Group and Live Chat Show Notes 02:02 Dr. Bikman’s Journey: He was an exercise enthusiast, with two degrees in exercise physiology. He was fixated upon calories and the “eat less – exercise more” model. It would not work consistently. During PhD studies, he learned that insulin is the metabolic key. As insulin goes, so goes body fat. Now that he has his own lab, the relevance of insulin upon normal metabolic health is his area of study. 03:11 Insulin is needed to Grow Fat Cells: Progenitor (stem) cells in a dish need a spike in insulin of a certain size and over a certain amount of time in order for them to become fat cells. This is adipogenesis, the creation of adipocytes. 03:35 Distortion of the Fat Cell: Within the adipocytes in adult humans, insulin initiates lipogenesis, the creation or expansion of the lipid droplet or bulge of fat within the fat cell. When you look at a fat cell under a microscope, the mitochondria, nucleus and o Continue reading >>

Escaping The Fat Trap

Escaping The Fat Trap

Once you’ve been heavy for some time, your high insulin levels can make it hard to succeed in losing weight. Trying diet after diet and failing on each and every one is depressing. But when you discover the perfectly natural bodily process called lipolysis, hope can replace despair. To a person longing to lose weight, Nirvana is the definition of lipolysis: the process of dissolving fat. When you burn fat, it breaks down into glycerol and other fatty acids. How does the process actually work? Are there any drawbacks? There are plenty of laypersons and even physicians who think there must be. Burning off one’s fat sounds like a faddish trick. These folks give a skeptical shrug and say, "I’m sure people lose some weight with the Atkins approach, but don’t they gain it right back again?" The interesting thing is that if you adhere to the four phases the Atkins approach—which includes finding your Atkins Carbohydrate Equilibrium (ACE), meaning the amount of carbohydrates you can still consume and neither gain nor lose weight—you won’t regain the weight. The phase known as Lifetime Maintenance, though more indulgent, evolves naturally from the three weight-loss phases, thereby gradually teaching you a permanent way of eating that still moderates carbohydrate intake to the degree that is necessary for your individual metabolism. Many controlled carbohydrate regimens have been proposed over the years. They work with some degree of effectiveness for some people. However, many of them do not bring carbohydrate intake down to a level that will permit lipolysis. For people who suffer from metabolic obesity and have great difficulty losing, that is a grave weakness. Atkins, on the other hand, starts you off consuming 20 grams of carbohydrates. You then proceed at your Continue reading >>

Hibernating Bears 'a Metabolic Marvel'

Hibernating Bears 'a Metabolic Marvel'

For the first time, scientists say they have been able to monitor a bear's vital signs continuously during a six-month period of hibernation. To their surprise, the researchers discovered that despite lowering its metabolism by 75 percent, a hibernating bear's internal temperature barely drops at all. The bear study took place at the University of Alaska, Fairbanks. The bears spent the winter in a hibernaculum — basically a big box. The researchers weren't sure whether the bears would be willing to spend the winter in this small, artificial cave. "We anticipated they might just tear the place up or go on strike or something," says Brian Barnes, one of the authors of the new study. "But they actually showed very natural behavior of getting ready to hibernate. They curl up, they go to sleep. They begin to quiet their heart rate, slow their breathing and their metabolic rate plunges." The fact that a bear could reduce its metabolism so much with such a small drop in temperature was a surprise. Barnes says two factors appear to be responsible. First, a bear has a lot of fat and thick fur, so it is well-insulated. Second, when a bear's internal temperature drops below about 90 degrees Fahrenheit (99 degrees is normal for a bear), it starts to shiver. The shivering produces heat, and the bear's temperature rises a few degrees. This periodic shivering occurs throughout the winter. 'A Closed System' Barnes says just about everything a bear does while hibernating is remarkable. "Bears don't eat, drink, urinate or defecate for six or seven months," he says. They make their own water, probably by metabolizing fat, and they get rid of wastes by breaking them down internally. "They're a closed system. All they need is air, and they can do just fine. They're a metabolic marvel," he Continue reading >>

The Biochemistry Of Mammalian Hibernation As A Possible Basis For Therapies

The Biochemistry Of Mammalian Hibernation As A Possible Basis For Therapies

Hi there ! Interesting ! This could turn out helpful, especially the limb/organ regeneration (like geckos/salamanders/lizards cell transdifferentiation to regrow their cut-off limbs/tails...regrow a human arm or leg after losing it. But 'don't lose your head' (pun!) over losing your other limbs (joke)). Regrowing your head would still not stop you from dying from losing it in the first place. It's the regrowing of organs that has me more interested, limbs ok, but organs...that's a whole different thing. If we could regrow/regenerate our organs, except perhaps brain, to the exact same state during youth; that would be a form of rejuvenation. Exceptional cancer resistance by (NMRs) naked mole rats (large hyaluronan molecules, plump skin for hypoxic environment, altered p53-p16-p21 levels and stronger stromal cell barriers that inhibit tumor propagation to other organs) is definitely something we can do with; although, this is mixed stuff. Certain studies showed an actual increase in hyaluronic acid (HA) during human cancers (neoplastic remodelling is what is happening). Inflammation is characterized by higher amount of short-chain/fractured hyaluronan while anti-inflammation in ECM has more long-chained hyaluronan. Still, this is inconclusive, an small and large chain HA have been found during pathological remodelling (like fibrosis). ECM remodelling is complex and cancer neoplasticity ECM remodelling is too; it messes up HA, not like in naked mole rats. I'm not so sure increasing long-chain HA would amount to all that much, in humans, plumper youthful skin, like a naked mole rat, such as in little children or babies would not stop cancer (kigs gets cancers...anyways and have higher HA and plumper skin/tougher organ stromal barriers). Our cell density/organ complexity/siz Continue reading >>

The Ketogenic Diet As The Default Human Diet: An Energy Perspective

The Ketogenic Diet As The Default Human Diet: An Energy Perspective

The conditions under which the liver delivers optimal fuel on demand may be the conditions under which it evolved. When you are on a ketogenic diet, the mitochondria in your cells — the parts of the cells that produce energy — actually switch from primarily using sugar for fuel to primarily using fat for fuel. They use fat mostly in a form called ketone bodies (or, commonly, ketones), thus a ketogenic diet. (See Keto-adaptation: what it is and how to adjust for more on this process of switching fuels.) Sugar-based living (from a diet with more than about 5% calories from carbohydrate) When you are using the sugar-based system, all of the cells in your body constantly take sugar out of your bloodstream. It's hard for your body to keep up, and you need to frequently refuel by eating carbohydrate-containing food. Getting sugar out of the carbohydrates that you eat is a blunt tool. Unless you eat in a trickling stream, you will consume more sugar than is safe to hold in the bloodstream at once. That sugar has to be quickly removed, because high blood sugar damages your cells. So a flood of insulin comes in to initiate the process of sugar removal. There is some limited storage space in the liver, but when that is full, the rest basically gets stored as fat. Soon however, the job is done. Your blood sugar is back in a safe range. Your body cells are still demanding sugar, though, and your blood sugar starts to drop too low. Your liver can release some sugar back into the bloodstream, but not fast enough to keep up with demand, so you get tired and hungry, and the process starts all over. People on carbohydrate-based diets typically have to "snack" every couple of hours. Endurance athletes have to stop and eat sugar just to get through their events. On a sugar-based metab Continue reading >>

Vegan Ketogenic Diet For Cancer

Vegan Ketogenic Diet For Cancer

What is a vegan ketogenic diet and how can it help people being treated for cancer? Why is this diet so important to help maintain and restore our health? Is the vegan ketogenic diet scientifically proven and could it help people being treated for cancer? We are going to cover all these questions here for you. Individuals will visit us and ask if we have research and proof that what we do at An Oasis of Healing works? Where on the other hand, these individuals will never ask the white coats or doctors at Dana Farber if they have the research and proof that the cancer treatments they are about to receive will work? There is a large amount of scientific proof on whether a vegan ketogenic diet is effective. If you’re interested in the research and scientific proof of how this works, buy the book by Thomas Seyfried Ph.D., “Cancer as a Metabolic Disease”. What is a vegan ketogenic diet? The word keto is derived from ketosis or ketones. People have fatty acids which is used to store energy. When those fatty acids are utilized for energy, they go through a process of being broken down into what’s called ketone bodies. These ketone bodies are ushered into cells and are then broken down further and transformed into fuel for the human body. This process is efficient and works perfectly in the storage of fats for conversion into energy. This process stores double the energy of carbs. When someone fasts they are actually on a ketogenic diet. The reason to be on this diet is to produce ketones. When ketones are produced we are able to get into a metabolic condition which is called ketosis. Water happens to be the best form of a ketogenic diet. However, it’s not great for someone who had cancer because they would become to weak. They need the fat and nutrients that come wit Continue reading >>

The Bears Take On Hibernation Biology Essay

The Bears Take On Hibernation Biology Essay

Disclaimer: This essay has been submitted by a student. This is not an example of the work written by our professional essay writers. Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of UK Essays. Bears are members of the family Ursidae, there are eight species alive today, with a large geographical range. They are found in North America, South America, Asia and Europe; they occupy a large range of habitats, from the Arctic tundra to temperate forests (Craighead Institute 2010). During winter, bears enter a state of dormancy. Most animal species become dormant to some extent during their lives, as an energy saving mechanism. Sleep is the archetypal form of dormancy, with animals retiring to a nest, assuming a sleep posture, remaining behaviourally quiescent and exhibiting elevated arousal thresholds (Heller et al 2004). A more extreme form of dormancy is torpor. Torpor is characterised by a controlled reduction of body temperature (Tb), metabolic rate, and other physiological functions (Geiser 2004). Torpor has the superficial appearance of sleep, indeed torpor and sleep are believed to be homologous. This has been supported by numerous electroencephalographic (EEG) studies (Heller et al. 2004). There are two basic forms of torpor used by heterothermic animals, hibernation (or prolonged torpor) and daily torpor. Daily torpor is usually not as deep as hibernation, lasts only for hours rather than days or weeks, and is usually interrupted by daily foraging and feeding (Geiser 2004). There is a lack of agreement over whether the winter dormancy of bears constitutes "true" hibernation. Hibernation is defined as "the dormant condition into which many animals and plants pass whe Continue reading >>

5 Stages Of Activity And Hibernation

5 Stages Of Activity And Hibernation

The annual cycle of black bear activity and hibernation has five stages: The stages differ in biochemistry, physiology, appetite, and level of activity. The onset and duration of the stages are genetically programmed to fit regional norms of food availability, which differ across America. When people defined hibernation simply in terms of temperature reduction, bears were not considered hibernators. However, when biologists discovered the many metabolic changes that let black and grizzly bears hibernate up to 7 ½ months without eating, drinking, urinating, or defecating, they realized that body temperature was only a small part of hibernation. They redefined mammalian hibernation as a specialized, seasonal reduction in metabolism concurrent with scarce food and cold weather (Watts et al. 1981). Black bears are now considered highly efficient hibernators. Before researchers from the Wildlife Research Institute videotaped 3-year-old June digging this den in Eagles Nest Township, Minnesota, they had no idea some bears made dens so early—July 19, 2004. It was the first time researchers watched a bear dig a den. The most interesting part happened when she encountered a 68-pound rock. She did not make futile attempts to roll it up the steep incline of the entryway. In 2003, the BBC phoned researchers for help with a documentary using new thermal imaging technology. The telephone conversation sounded something like: BBC: “We’re looking for someone dumb enough to try putting tiny cameras under a mother black bear with cubs in a den. Do you have such a person?” Researcher: “Will it have educational value that we can use at the Bear Center someday? BBC: “Yes. One of the cameras will make the very first thermal images of heat loss patterns in dens.” Temperatures rem Continue reading >>

Going Low-carb Too Fast May Trigger Thyroid Troubles And Hormone Imbalance

Going Low-carb Too Fast May Trigger Thyroid Troubles And Hormone Imbalance

If you’ve been turned on to the low-carb Paleo diet craze, you may have noticed increased energy, better digestion and happier mood, and a shrinking waist line. Good for you. But some folks who’ve taken the Primal leap—particularly those who were previously on a high-carb diet—have been faced with unexpected side effects waving them back to the world of bread, sugary fruits and sweet potato casserole. Interestingly, these side effects include a wide range of symptoms that are nearly identical to symptoms of severe thyroid hormone deficiency. More interestingly, lab tests often show normal or near normal thyroid function. More interesting still is that these symptoms seem to only be relieved by adding back carbs into the diet, sometimes upward of 300 grams—a level I consider to be very likely to harm. Why is this happening? Is it that low-carb simply doesn’t work for everyone, or is something else going on? In an effort to get to the bottom of this, low-carb blogger Jimmy Moore is asking his cadre of low-carb literate practitioners to weigh in on the issue with our opinions. This so happens to be an issue I’ve been pondering since reading about the controversy over safe starches, and a couple pieces of the puzzle recently fell into place that I think I add up to at least one explanation for the debilitating symptoms some people develop on going low-carb, and offer a method for anyone going low-carb to do so without problems. Here’s what I discovered about those with thyroid problems. Abrupt Change May Be too Much For the Thyroid People who run into trouble going low-carb seem to follow a pattern. They follow any number of diets from SAD to vegan before making a relatively abrupt switch to a low carb (often less than 50 gm) diet. At first they lose weight Continue reading >>

Talk:ketosis

Talk:ketosis

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Ketosis. PubMed provides review articles from the past five years (limit to free review articles or to systematic reviews) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC WikiProject Medicine (Rated C-class, Mid-importance) This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine. C This article has been rated as C-Class on the project's quality scale. Mid This article has been rated as Mid-importance on the project's importance scale. This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Assigned student editor(s): Matt34am. Assigned peer reviews: Ashbyaa, Gruskyd. Ketosis v Ketoacidosis?[edit] My understanding is that these are parts of the same spectrum; severe ketosis is called ketoacidosis. This article implies that they're different things. Anyone have a source? Friday 21:24, 22 July 2005 (UTC) Yes, Harrison's Principles of Internal Medicine, see the section on the body's defense against hypoglycemia.--Silverback 06:32, July 23, 2005 (UTC) Sort of. Ketoacidosis is when you have so many ketone bodies that your blood becomes acidic. So it's sort of like having severe keto Continue reading >>

How Do Bears Hibernate?

How Do Bears Hibernate?

Somewhere near Portsmouth there is probably a bear hibernating. How do bears do that? The first thing to clarify is that hibernating is not sleeping. The brain activity of hibernating animals is like awake brain activity. In fact when they “wake up” from hibernating many mammals show signs of sleep deprivation and may have to sleep more for a few days. These are some things that are known about hibernation in bears.(1) – For as many as 7 months of hibernation bears go without eating, drinking, defecating or urinating, in contrast to chipmunks and other small mammals that get up to do that stuff every week or so. – Bears hibernate at or near normal body temperature, in contrast to the those other small mammals who hibernate with a body temperature near ambient, approaching but not falling below 0°C. – Weight loss in hibernating bears ranges from 16% to 37% of body weight at the start of hibernation. So they will need to put that weight back on before the next hibernation. – Bears conserve lean body mass during hibernation using almost only fat combustion for energy needs. – So fat content at the start of hibernation is 36% to 38% of total weight in black bears and 49% in polar bears and declines proportionate to the decline in body weight. – Blood lipids (cholesterol, triglycerides, and free fatty acids) increase during hibernation, a result of increased combustion and decreased production of fat. – Ketosis which is a sign of fat burning in starving humans does not occur in hibernating bears. – Total body water, blood volume, and water content of plasma and red blood cells do not change during hibernation in black bears. – During hibernation, black bears maintain bone mass and measures of bone formation. In other species undergoing long periods of Continue reading >>

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