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Alcoholic Lactic Acidosis Treatment

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So what is dextrose? How should you use apply it to your current supplement protocol, and should you use it? Find everything about dextrose in this episode of ATSGS! Dextrose is one of the fastest absorbing types of simple carbohydrates. Dextrose is used by a variety of athletes including bodybuilders to induce an insulin spike and replace the glycogen in the muscle which is lost during an intense workout session. Dextrose -- Fat storage VS Muscle Storage: There are 3 options for carbs when they enter into the blood stream. They can either by burnt for fuel, get stored in the muscle or get stored as fat. If you're insulin sensitive, 80 percent of the carbs you eat will go to your muscle cells. If you're NOT insulin sensitive, 80 percent will go to your FAT cells! Dextrose and Sports: Dextrose is very commonly used by anyone looking to gain size quickly, but it can also be used by endurance athletes who run a lot. Anybody who workouts for a long period of time would likely see benefit from taking dextrose. Who can benefit from using dextrose supplements? Like I mentioned above, dextrose can be used by pretty much any athlete, especially any body looking to gain a lot of size quickly

Treatment Of Alcoholic Acidosisthe Role Of Dextrose And Phosphorus

We have made serial metabolic observations in 18 acute episodes of alcoholic ketoacidosis in ten patients. Data from patients treated with only saline initially were compared to data from patients who received modest amounts of intravenous dextrose (7.0 to 7.5 gm/hr). More rapid improvement in the acidotic state was seen in the latter group (P <.001). The quicker decline in absolute levels and ratio of -hydroxybutyrate to acetoacetate when glucose was given suggests that this treatment induced mitochondrial oxidation of the reduced form of nicotinamide adenine dinucleotide (NADH). Since phosphorus is a critical cofactor necessary for NADH oxidation and the glucose-induced correction of the acidosis was associated with a rapid decline in serum phosphorus from an initial mean of 6.79 .82 mg/100 ml SEM to 0.96 0.12 mg/100 ml in 24 hours, we propose that glucose enhanced the mitochondrial capacity to oxidize NADH by increasing hepatocyte phosphorus. This effect combined with decline in free fatty acid levels results in reversal of acidosis. Our data suggest that glucose provides the safest, most effective treatment for this disorder; addition of either insulin or bicarbonate is usuall Continue reading >>

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  1. kaazoom

    I recently had my Hba1c tests and it was over 9 . The doctor increased my metformin from 1 tablet twice a day to 2 tablets twice a day. I was told to start by increasing the morning dose and after 2 weeks increase my evening dose. I have had a lot of stomach discomfort, and terrible indigestion since increasing the does. I work up the other morning in extreme pain like I was having a heart attack. The pain went after taking antacids. Indigestion is something I get every now and then, but it is usually due to eating something I should avoid. This day I don't think I had eaten anything that would cause it. But I had increased my evening dose of metformin, so I was and am on 4 tablets a day. I have had more general discomfort than usual, muscle pains and more breathlessness.The difficult is I have other health problems so knowing which one is caused by which is a nightmare.
    I also tend to let myself get dehydrated at night as I have bladder problems which I having investigations for at the moment. If I don't stop drinking about at about 7pm I end up waking numerous times to go to the loo. The only drink I have after 7pm is a few sips of water to help swallow my medications.
    Sorry for being so long winded. My main question is does lactic acidosis come on suddenly, or does it build up over days or weeks?
    Paul

  2. destiny0321

    Hi. If you find your metformin could be causing problems which it did with me runs,breathing problems and generally really poorly go back to your gp I did and I was put on me form in slow release which is much gentler on the stomach hope this helps you destiny
    Sent from the Diabetes Forum App

  3. kaazoom

    Thanks.
    I've got to see my GP next week about something else so I will talk to him about it. I don't think I have lactic acidosis, I was curious about whether it was sudden or gradual onset. I saw something on the TV yesterday that said patients are risking their health because they don't read the information sheets that come with their medication. So I had a look at mine. It gave a number of symptoms to watch out for including severe indigestion,muscle spasms etc it said if you have any of these symptoms when taking Metformin to go immediately to the nearest hospital A&E because these symptoms can be signs of lactic acidosis. I don't think what I'm experiencing is severe enough for A&E.
    I had muscle spasms, pains and a number of the other symptoms list prior to my diabetes diagnose due to other illnesses, and they can vary in severity. They seem to have got somewhat worse since my metformin was increased, but it could just be coincidence. The indigestion and stomach problems are particularly bad. My feeling is my body is taking time to adapt to them. i will ask my doctor if I can change to a slow release version.
    Paul

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Metabolic Abnormalities In Alcoholic Patients: Focus On Acid Base Andelectrolyte Disorders

E-mail: [emailprotected] , [emailprotected] Received Date: December 20, 2014; Accepted Date: January 24, 2015; Published Date: January 27, 2015 Citation: Moses Elisaf MD, Rigas Kalaitzidis MD (2015) Metabolic Abnormalities in Alcoholic Patients: Focus on Acid Base and Electrolyte Disorders. J Alcohol Drug Depend 3:185. doi:10.4172/2329-6488.1000185 Copyright: 2015 Moses Elisaf MD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Alcoholic patients commonly develop a variety of acid-base and electrolyte disturbances. The aim of this review is to describe the most commonly encountered abnormalities and their significant role in the patients morbidity and mortality. Physicians should be aware of these clinically important disturbances caused by alcohol abuse and their underlying pathophysiological mechanisms involved for their appropriate management. Alcoholic Keto Acidosis (AKA) is a medical emergency is more common than previously thought and is characterized by an increased anion gap metabo Continue reading >>

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  1. TheCommuter

    You can post this question on this site's Nursing Student Assistance Forums and perhaps get an answer. One of our frequent users, Daytonite, loves to give detailed answers to these types of questions.
    http://allnurses.com/forums/f205/

  2. ICRN2008

    Here is the formula for anion gap:
    Agap = Na + K - Cl -CO2
    I would think that the doctor would be monitoring the glucose level (not the agap) to determine when to stop the insulin drip. Anyone else have an idea?

  3. P_RN

    One of our wonderful members Mark Hammerschmidt has a great FREE MICU site:
    http://www.icufaqs.org/
    Check section 4.2
    It's all acidosis/alkalosis

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Alcoholism is disease, heres some resources to help you fight back: Responsible Drinking: A Moderation Management Approach http://amzn.to/1ZdgP9f I Need to Stop Drinking!: How to get back your self-respect. http://amzn.to/1VEqbeU Why You Drink and How to Stop: A Journey to Freedom: http://amzn.to/1Q8pAv2 Alcoholics Anonymous: The Big Book: http://amzn.to/1N0rttl Alcoholics: Dealing With an Alcoholic Family Member, Friend or Someone You Love: http://amzn.to/1j9cvH4 Watch more How to Understand Alcoholism videos: http://www.howcast.com/videos/517398-... The question that has been asked of me is if alcoholism can lead to diabetes. And if so, how? The answer is chronic alcohol use can lead to diabetes. The way it leads to diabetes is that chronic alcohol use can cause inflammation of the pancreas, and chronic inflammation of the pancreas can affect the production of insulin in the body. And that's what causes diabetes. So that is why alcohol can be an actual primary determinate of diabetes. The other way that heavy alcohol use can lead to diabetes or exacerbate diabetes is that alcohol has a high content of sugar. So if one is already diabetic, alcohol is really not indicated because o

Alcoholism And Lactic Acidosis

Learn more about the SDN Exhibition Forums for exclusive discounts and contests. So the way I understood this is that both alcohol metabolism and latcate to pyrvuate conversion require NAD, and with too much alcohol consumption the body uses up all the NAD for alcohol metabolism right? The part that I'm a bit troubled with this mechanism is that unless we are doing extreme exercise, we don't really generate lactic acid. In most cases, the body uses oxidative phosphorylation, right? So lactic acidosis will most likely occur when you drink alcohol and then do extreme exercise, correct? SDN Members don't see this ad. About the ads. My understanding is that high NADH levels from EtOH metab drives the pyruvate -> lactate conversion. So you don't need to be exercising +drinking, either will do it on their own. I actually enjoy your questions, though some things are really easily looked up. The several different causes of lactic acidosis: I actually enjoy your questions, though some things are really easily looked up. The several different causes of lactic acidosis: But the reasons behind why lactic acidosis occurs for these is significantly different.... For example, in exercise- lactic Continue reading >>

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  1. FooFatFighters

    So I've read on r/keto that you can use a cheap breathalyzer to test for acetone on the breath which indicates your level of ketosis. The trick is to use a cheap, crappy alcohol breathalyzer to test and not an expensive fancy one.
    The cheap ones can't tell the difference between alcohol and acetone, the good ones (like the police carry) only measure alcohol and ignore acetone (ketones).
    So I bought this breathalyzer http://www.ebay.com/itm/231045711618 from ebay
    And folks in r/keto say that blowing 0.01—0.05 is good and shows youre in ketosis. I just blew 0.14 which I can believe because I've been doing less than 15g net carbs/day this week and I lost three pounds. I put a photo of the readout in my profile pics.
    Has anybody else tried this? What reading levels should I be watching for? This seems a lot better than peeing on a stick.

  2. Booksandbeaches

    That's interesting and affordable too.
    I'm interested in what the veteran keto folks have to say.
    I found this study that says breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals. It's not a long-term study though, but still intriguing.
    http://ajcn.nutrition.org/content/76/1/65.full

  3. FooFatFighters

    I bought a nice breathalyzer on Amazon.com but it was a good one and it didn't register breath acetone at all, only alcohol so I returned it. Seems like this cheap one does the trick. I'm meeting-up with a friend tommorrow and hopefully she hasn't had any drinks and isn't doing keto, I'm going to get her to blow into it for a baseline test.

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