What is MATERNAL DEATH? What does MATERNAL DEATH mean? MATERNAL DEATH meaning - MATERNAL DEATH definition - MATERNAL DEATH explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Maternal death is defined by the World Health Organization (WHO) as "the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes." The world mortality rate has declined 45% since 1990, but still every day 800 women die from pregnancy or childbirth related causes. According to the United Nations Population Fund (UNFPA) this is equivalent to "about one woman every two minutes and for every woman who dies, 20 or 30 encounter complications with serious or long-lasting consequences. Most of these deaths and injuries are entirely preventable." UNFPA estimated that 289,000 women died of pregnancy or childbirth related causes in 2013. These causes range from severe bleeding to obstructed labour, all of which have highly effective interventions. As women have gained ac
Alcoholic Ketoacidosis As A Cause Of Death In Forensic Cases
Alcoholic ketoacidosis as a cause of death in forensic cases Research output: Contribution to journal Journal article Alcoholic ketoacidosis as a cause of death in forensic cases. / Thomsen, Jrgen L.; Felby, Sren; Nielsen, Erik; Theilade, Peter. In: Forensic Science International, No. 75, 1995, p. 163-171. Research output: Contribution to journal Journal article Thomsen, JL, Felby, S, Nielsen, E & Theilade, P 1995, 'Alcoholic ketoacidosis as a cause of death in forensic cases' Forensic Science International, no. 75, pp. 163-171. Thomsen, J. L., Felby, S., Nielsen, E., & Theilade, P. (1995). Alcoholic ketoacidosis as a cause of death in forensic cases. Forensic Science International, (75), 163-171. Thomsen JL, Felby S, Nielsen E, Theilade P. Alcoholic ketoacidosis as a cause of death in forensic cases. Forensic Science International. 1995;(75):163-171. Thomsen, Jrgen L. ; Felby, Sren ; Nielsen, Erik ; Theilade, Peter. / Alcoholic ketoacidosis as a cause of death in forensic cases. In: Forensic Science International. 1995 ; No. 75. pp. 163-171
It is often assumed that herbs and supplements are completely safe. Consumers often do not consider the potential for interactions with their medications. How common are supplement-drug interactions? What kind(s) of impact do they have? This presentation will help answer these and other important questions involving supplement-drug interactions. At the conclusion of this presentation, participants will be able to: Describe the prevalence and impact of supplement-drug interactions. Discuss the types of evidence used to document supplement-drug interactions. Differentiate between pharmacokinetic and pharmacodynamic interactions. Describe the physiologic function of cytochrome P450 and other metabolic enzymes. Define a system to evaluate the significance of supplement-drug interactions. List examples of significant supplement-drug interactions to avoid. Recognize tools used to identify and prevent supplement-drug interactions. Speaker Bio Forrest Batz received a Doctor of Pharmacy degree from the University of California, San Francisco School of Pharmacy and completed a pharmacy residency at the Department of Veterans Affairs Medical Center in Tucson, AZ. With a background in drug inf
Alcoholic Ketoacidosis As The Cause Of Death: Thomsen And Co-workers Came First | Marc Augsburger - Academia.edu
Alcoholic Ketoacidosis as the cause of death: Thomsen and co-workers came first Alcohol and Alcoholism Vol. 49, No. 6, pp. 687688, 2014 LETTERS TO THE EDITOR Alcoholic Ketoacidosis as a Cause of Death, REFERENCES Who Came First? Denmark LN. (1993) The investigation of beta-hydroxybutyrate as a marker for sudden death due to hypoglycemia in alcoholics. Jrgen L. Thomsen* Forensic Sci Int 62:22532. Palmiere C, Augsburger M. (2014) The postmortem diagnosis of Institute of Forensic Medicine, University of Southern Denmark, alcoholic ketoacidosis. Alcohol Alcohol 49:27181. Winslwparken 17B, DK-5000 Odense C, Denmark Thomsen JL, Theilade P, Felby S et al. (1993) Alcoholism and ketoacidosis. Forensic Sci Int 60:34. *Corresponding author. Tel.: +45-65503001; Fax: +45-65916227; E-mail: [email protected] doi: 10.1093/alcalc/agu059 Advance Access publication 21 September 2014I read with interest the article The Postmortem Diagnosis ofAlcoholic Ketoacidosis by Palmiere and Augsburger (2014). Alcoholic Ketoacidosis as the Cause of Death: However for the sake of truth I must protest against thestatement on page 272: The first report in the forensic field Thomsen and Co-workers Came Firstsug
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Sudden Unexplained Death In Alcohol Misuse (sudam) Patients Have Different Characteristics To Those Who Died From Sudden Arrhythmic Death Syndrome (sads)
, Volume 13, Issue3 , pp 278283 | Cite as Sudden unexplained death in alcohol misuse (SUDAM) patients have different characteristics to those who died from sudden arrhythmic death syndrome (SADS) There is growing awareness of sudden unexplained death in alcohol misuse (SUDAM) in which there is no obvious cause of death, no evidence of acute alcohol toxicity or alcoholic ketoacidosis, and the heart is morphologically normal. This study describes the characteristics of a cohort with SUDAM from a tertiary cardiovascular referral center and compares the findings with those of individuals who died from sudden arrhythmic death syndrome (SADS). Cases in this retrospective cross-sectional study were identified from a database of referrals to our center spanning approximately 40 years. Cases with recorded heavy use of alcohol and non-alcohol users were selected, then limited to those with SUDAM or SADS aged 16 to 64 years. 62 cases of SUDAM and 41 cases of SADS were identified. The SUDAM group were older than the SADS group; mean age 35.8 years and 27.7 years respectively (P=0.0002). There was also a higher incidence of significant psychiatric illness in SUDAM (19.7%) than SADS (2.4%) case
Abstract Seven episodes of severe ketoacidosis in six nondiabetic patients were recognized at this hospital within an eighteen month period. All were women; one pregnant patient experienced two episodes at twenty-eight and thirty-two weeks' gestation. All patients admitted to heavy chronic alcohol intake and drinking binges. On admission, these patients were conscious and alert. Mean values were 143 mg./100 ml. for plasma glucose and 7.25 for art ...
Workup When a chronic alcoholic presents with signs of AKA, the clinician should carefully evaluate the patient, obtain a history, perform a physical exam, and order the appropriate laboratory tests. Laboratory tests and results A comprehensive metabolic profile will allow the medical team to determine the overall clinical picture of the patient. This includes measurement of serum electrolytes, glucose, blood urea nitrogen (BUN), creatinine, lipa ...
We analyzed the postmortem blood of a total of 100 fatal cases for beta-hydroxybutyric acid (BHBA). In 25 cases of sudden and unexpected death of alcoholics we found pathologically increased levels of BHBA of 1260 to 47 200 (median 8000) mol/L. This led us to the diagnosis of an alcoholic ketoacidosis (AKA) as cause of death in these cases. The control group of 69 postmortem cases revealed that BHBA concentrations below 500 can be regarded as no ...
Increased production of ketone bodies due to: Dehydration (nausea/vomiting, ADH inhibition) leads to increased stress hormone production leading to ketone formation Depleted glycogen stores in the liver (malnutrition/decrease carbohydrate intake) Elevated ratio of NADH/NAD due to ethanol metabolism Increased free fatty acid production Elevated NADH/NAD ratio leads to the predominate production of β–hydroxybutyrate (BHB) over acetoacetate (AcAc ...
Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia. alcoholic ketoacidosis the fall in blood pH (acidosis) sometimes seen in alcoholics and associated with a rise in the levels of serum ketone bodies. alcoholic ketoacidosis Acute metabolic ketoacidosis classically seen 1–2 days after an alcohol binge coupled with a decrease in “real” food, resulting in a starvation response, which is exacerbated by vomiting, beta-hydroxybutyrate a ...
1 A chronic alcoholic with severe metabolic acidosis presents a difficult diagnostic problem. The most common cause is alcoholic ketoacidosis, a syndrome with a typical history but often misleading laboratory findings. This paper will focus on this important and probably underdiagnosed syndrome. 2 The disorder occurs in alcoholics who have had a heavy drinking-bout culminating in severe vomiting, with resulting dehydration, starvation, and then a ...