Acute Kidney Injury In Dka

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Acute Kidney Injury Common In Pediatric Diabetic Ketoacidosis

medwireNews: Almost two-thirds of children hospitalized with diabetic ketoacidosis (DKA) develop acute kidney injury (AKI) within 24 hours of hospitalization, study findings indicate. The most severe cases of AKI (stage 2 or 3) were significantly associated with increased volume depletion and more severe acidosis, the researchers report. “Overall, these data suggest that clinicians should consider AKI as a frequent complication that accompanies pediatric DKA and should be especially alert to its presence in severe presentations of DKA,” Constadina Panagiotopoulos (University of British Columbia, Vancouver, Canada) and co-authors write in JAMA Pediatrics. They reviewed the medical records of 165 children (median age 10.6 years) with type 1 diabetes who were hospitalized for diabetic ketoacidosis between 2008 and 2013, 75.8% of whom were newly diagnosed with type 1 diabetes during their stay. Of these, 106 (64.2%) met the Kidney Disease/Improving Global Outcomes serum creatinine criteria for AKI, of which 34.9% was stage 1, 45.3% stage 2, and 19.8% stage 3. In 99.1% of cases, AKI occurred within 24 hours of hospitalization, and it resolved with conservative fluid management by 72 Continue reading >>

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Popular Questions

  1. OutcastInZion

    Hi Ladies!
    I have been doing keto for about 2-3 months now to lose the last 15lbs towards my weight goal. I am 34 (going 35), 4'11", and currently 117lbs. My goal is to get to 110lbs and originally thought that I could maybe push to 100-105lbs.
    I recently found out that I am pregnant. For those who have lost weight during pregnancy (or trying to), do you stick to your original macros? Since there will be a weight gain during pregnancy, what would be the ideal gain on keto and still stay on target for weight loss?
    I am a slow to weight loss, and I imagine I would have to lose the extra weight after pregnancy or achieve weight goal before 2nd-3rd trimester.
    As a side note, I did have a lot of issues during last pregnancy and been working on weight loss for the last year.
    Thanks in advance

  2. sellyberry

    I'm 5'6" and can't imagine being 117.
    Rather than trying to lose weight at all, even in the first trimester, I'd recommend aiming to simply maintain your current weight for a while. You are not overweight (I think?) so gaining 25lbs or so through the whole pregnancy is expected and even encouraged. Necessary weight gain.
    You should gain weight.
    It's ok.
    A lot of stuff is going to happen besides the growing baby. You're body will grow a new organ, the placenta. It will fill with fluid over time to cushion the baby, allow for movement and growth, assist in respiratory and digestive development, and temperature control. You will have about a 50% increase in blood. Your heart will grow bigger to pump that blood. Organs with shift and stretch to make room. Your body will also start storing choice nutrients in preparation for breastfeeding.
    All that adds up.
    Now I see this isn't your first. But I don't know how a second pregnancy differs so I'm not changing it.

  3. Ocipura

    Agreed! It's not advisable to lose weight on purpose during pregnancy. Even for very overweight people like myself, the most I'd say is aim to maintain weight of you can for the first trimester and maybe part of second.

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