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Acid Ketosis

The Interplay Of Exercise And Ketosis Part I

The Interplay Of Exercise And Ketosis Part I

The interplay of exercise and ketosis – Part I I embarked on a self-experiment last weekend to see if I could better understand the interplay between the different types of exercise I do and ketone production (beta-hydroxybutyrate, or B-OHB, to be specific).  To be clear, nothing I do with a sample size of one “proves” anything, but sometimes self-experiments can help you formulate hypotheses and, if nothing else, understand how your body works.  Consider the parable of the black sheep.  If you see even a single black sheep in the field, depending on your field of training, you can draw conclusions: Three scientists were on a train and had just crossed the border into Scotland. A black sheep was grazing on a hillside. The biologist peered out of the window and said, “Look! Scottish sheep are black!” The chemist said, “No, no. Some Scottish sheep are black.” The physicist, with an irritated tone in his voice, said, “My friends, there is at least one field, containing at least one sheep, of which at least one side is black some of the time.” My point is, even a self-experiment of one can be good for something. To test the relationship between exercise and ketosis I decided to examine my blood levels of glucose, B-OHB, and lactate immediately before and after three different types of workouts on three successive days.  This interplay is complex and no one knows “everything” about it, including the world’s experts (which I am not pretending to be).  I’m going to try to balance a fine line in this post – I want to be rigorous enough to explore the ideas with substance but not too detailed to put you to sleep.  I hope I am able to balance these forces adequately. If any of you are not familiar with the work of Jeff Volek and Steve Phinney, b Continue reading >>

What's A Keto Diet?

What's A Keto Diet?

What is a ketogenic diet and how does it work? The process was initially developed in 1924 by Dr. Russell Wilder as an effective, non-pharmacological treatment for intractable childhood epilepsy. The process works when the body is put into a metabolic state called Ketosis, where ketones become the main source of energy for the brain and body to function. The ketogenic diet plan is high in fat and low in carbohydrates while supplying adequate protein to the body. This specific combination changes the manner in which your body uses energy. Additionally, while reducing epileptic seizures, this process lowers glucose levels while improving the body’s resistance to insulin. So I know a lot of you are probably wondering "what is Ketosis?" am I right? By definition, it is when your body goes through a metabolic state in which the body transforms ketones created from fat into energy, instead of energy created from converting carbohydrates. What are they exactly did you ask? Biochemically speaking, ketones are organic, carbon-based compounds that contain a central carbon atom double-bonded to an oxygen atom and two carbon-containing substituents, denoted by “R.” Ketones are considered simple compounds because they do not contain chemical groups that are readily reactive. Fatty acids in the body are oxidized by the liver for energy production. There are 3 different ketone bodies produced in mitochondria of the liver: acetone, acetoacetic acid and beta-hydroxybutyric acid. Some of these fatty acids are oxidized by the liver for energy production while others can be partially oxidized to form the substrate acetoacetate, which is then converted to beta-hydroxybutyric acid; collective. These bodies produced in the liver are referred to as endogenous ketone bodies and are those Continue reading >>

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Great article. You actually answered my question as to the ratio of the 3 BHB salts which is quite helpful for me. For me, I had Keto O/S and found it quite good – my favorite was the chocolate swirl. But it was and is very expensive. Only 15-20 servings and would break the bank. So I turned to KetoCaNa and I’ve tried two flavours. Both of them were so salty that I almost threw up every time. Like flavoured sea water. Also only 15 serving per bottle. Then I turned to Ketond which is okay – Tigers Blood and Caramel Macchiato. What I like about Ketond is that it has a full 30 servings and is very transparent with it’s ingredients. It’s also the same price as Keto OS but you get 30 servings. But still, not the best taste. So in the end, I ordered 1kg of pure BHB Magnesium from a supplier in China and I will be developing my own Ketone product with 30 servings as a lower price than all the competitors, and with more Magnesium, and Calcium in it than Sodium so that it tastes the best and actually helps with weight loss (which Magnesium is proven to do at the right amount). What the companies don’t tell you is that actually Sodium BHB is the cheapest, then Calcium BHB and then Magnesium BHB to source so I would be interested in knowing if what you wrote is actually true or just an excuse to make the product cheaper. Probably a mix of both. So I have 2 questions Ben: 1. If you had to split the 11.7g of BHB into Sodium, Ca, and Mg, what ratio would you do for the best health results and potential weight loss? The current products on the market are about an 80/12/8 split. I would think it should be the other way around. 2. When I develop my own product and sell it, would you be up for sampling it and reviewing it on your website here? What flavours do you like/would Continue reading >>

Why Dka & Nutritional Ketosis Are Not The Same

Why Dka & Nutritional Ketosis Are Not The Same

There’s a very common misconception and general misunderstanding around ketones. Specifically, the misunderstandings lie in the areas of: ketones that are produced in low-carb diets of generally less than 50 grams of carbs per day, which is low enough to put a person in a state of “nutritional ketosis” ketones that are produced when a diabetic is in a state of “diabetic ketoacidosis” (DKA) and lastly, there are “starvation ketones” and “illness-induced ketones” The fact is they are very different. DKA is a dangerous state of ketosis that can easily land a diabetic in the hospital and is life-threatening. Meanwhile, “nutritional ketosis” is the result of a nutritional approach that both non-diabetics and diabetics can safely achieve through low-carb nutrition. Diabetic Ketoacidosis vs. Nutritional Ketosis Ryan Attar (soon to be Ryan Attar, ND) helps explain the science and actual human physiology behind these different types of ketone production. Ryan is currently studying to become a Doctor of Naturopathic Medicine in Connecticut and also pursuing a Masters Degree in Human Nutrition. He has interned under the supervision of the very well-known diabetes doc, Dr. Bernstein. Ryan explains: Diabetic Ketoacidosis: “Diabetic Ketoacidosis (DKA), is a very dangerous state where an individual with uncontrolled diabetes is effectively starving due to lack of insulin. Insulin brings glucose into our cells and without it the body switches to ketones. Our brain can function off either glucose or fat and ketones. Ketones are a breakdown of fat and amino acids that can travel through the blood to various tissues to be utilized for fuel.” “In normal individuals, or those with well controlled diabetes, insulin acts to cancel the feedback loop and slow and sto Continue reading >>

Tim Ferriss – 3 Day Fast Protocol Details – Get Into Ketosis Quicker And Easier

Tim Ferriss – 3 Day Fast Protocol Details – Get Into Ketosis Quicker And Easier

In Tim Ferriss’ new book Tools of Titans he puts forward a method to optimize the process of fasting. In his typical 80/20 style, he aims to get the most benefits, in the least amount of time. His recommended fast is conducted in a 3 day period, spanning Thursday evening to Sunday evening. 3-Day Fast Overview Stop eating Thursday night Friday morning go for a long walk to accelerate your transition into ketosis Friday and Saturday stay fasted, and consume moderate amounts of exogenous ketones and MCT oil (as needed), to give you a boost while you’re keto adapting. Sunday evening you break the fast. Here’s the process in more detail if you don’t have Tools of Titans to hand: Thursday Evening Eat a low carbohydrate dinner around 6pm. Make that the last meal of the day. Go to bed as normal. Friday Morning Drink some caffeine if needed, then get out the door and walk within 30 minutes of waking. Bring at least 1 litre of water, with some added salt (to prevent headaches/cramping), and sip as you walk. Walk for 3-4 hours(!). Filling up/buying more water as needed. Arrange phone calls for this time, to make the time productive. The idea behind the walk is that you use up your glycogen stores, forcing your body to move quicker into deep ketosis. The quicker you get into ketosis, the less time you spend feeling sub-optimal, and the less potential muscle wastage. Friday Day (post walk) Consume exogenous ketones or MCT oil 2-3 times throughout the day, where necessary. Tim primarily uses KetoCaNa & KetoForce as exogenous ketone sources. Both these products contain 11.7g of Beta-hydroxybuterate per serving, and each contain 16 servings. The key difference is that KetoForce is an unflavoured (alkaline) liquid. And KetoCaNa is an orange flavoured powder you can mix into wate Continue reading >>

What Is Ketosis?

What Is Ketosis?

Ketosis is a temporary physical condition marked by elevated levels of compounds known as ketone bodies in the body's tissues and fluids. The term "ketone bodies" refers to three different biochemicals: acetoacetate, beta-hydroxybutyrate and acetone. The first two molecules transfer energy produced in the liver to the tissues throughout the body; acetone is a breakdown product of acetoacetate, and is responsible for the sweet odor on the breath of people undergoing ketosis. The condition of ketosis typically represents a change in the way the body gets its energy. Normally, the body gets most of its energy by metabolizing glucose (a simple sugar) obtained from carbohydrates or stored in the liver and muscles as glycogen. But when unable to convert glucose into energy, the body switches to breaking down fat and converting it into energy. When this happens, the liver metabolizes fatty acids, producing energy-rich ketone bodies. The most common causes of ketosis are physiological, according to a 2000 article in the journal Diabetes/Metabolism Research and Reviews. Fasting, eating a low-carbohydrate/high-fat diet and engaging in high-intensity exercise can all lead to ketosis, because these activities deplete the body's stores of glucose. Because ketone bodies are acidic, a prolonged excess of the molecules in the blood can lead to a pathological form of ketosis, called ketoacidosis, in which the blood becomes acidic. Most commonly, ketoacidosis is associated with type 1 diabetes (and type 2 diabetes to a lesser extent). A lack of insulin, a hormone necessary for blood glucose to enter cells, causes glucose and ketone body concentrations to spike, lowering the blood's pH as it becomes more acidic. If left untreated, this condition, called diabetic ketoacidosis, can lead to Continue reading >>

What Everybody Ought To Know About Ketosis

What Everybody Ought To Know About Ketosis

Recently I wanted to explore the world of Ketosis. I thought I knew a little bit about ketosis, but after doing some research I soon realised how wrong I was. 3 months later, after reading numerous books, listening to countless podcasts and experimenting with various diets I know have a sound understanding of ketosis. This resource is built as a reference guide for those looking to explore the fascinating world of ketosis. It is a resource that I wish I had 3 months ago. As you will soon see, a lot of the content below is not mine, instead I have linked to referenced to experts who have a greater understanding of this topic than I ever will. I hope this helps and if there is something that I have missed please leave a comment below so that I can update this. Also, as this is a rather long document, I have split it into various sections. You can click the headline below to be sent straight to the section that interests you. For those that are really time poor I have created a useful ketosis cheat sheet guide. This guide covers all the essential information you should know about ketosis. It can be downloaded HERE. Alternatively, if you're looking for a natural and sustainable way to improve health and lose weight head to this page - What is Ketosis? What Are The Benefits from being in Ketosis? Isn’t Ketosis Dangerous? Ketoacidosis vs Ketosis What Is The Difference Between a Low Carb Diet and a Ketogenic Diet? Types of Ketosis: The Difference Between Nutritional, Therapeutic & MCT Ketogenic Diets Is The Ketogenic Diet Safe? Long Term Effects Thyroid and Ketosis - What You May Want To Know What is a Typical Diet/Macro Breakdown for a Ketogenic Diet? Do I Need to Eat Carbs? What do I Eat On a Ketogenic Diet? What Do I Avoid Eating on a Ketogenic Diet? Protein Consumption a Continue reading >>

Understanding Ketosis

Understanding Ketosis

To gain a better understanding of ketosis and the ketogenic diet, it is important to take a look at the physiology behind the diet. If you recall from the article What is a Ketogenic Diet? the goal of a ketogenic diet is to induce ketosis by increasing ketone body production. A key step in understanding the diet is to learn what ketosis is, what are ketones and what do they do. “Normal” Metabolism Learning the basics of the various metabolic processes of the body will better your ability to understand ketosis. Under the normal physiological conditions that are common today, glucose is our body’s primary source of energy. Following ingestion, carbohydrates are broken down into glucose and released into the blood stream. This results in the release of insulin from the pancreas. Insulin not only inhibits fat oxidation but also acts as a key holder for cells by allowing glucose from the blood to be shuttled into cells via glucose transporters (GLUT). The amount of insulin required for this action varies between individuals depending on their insulin sensitivity. Once inside the cell, glucose undergoes glycolysis, a metabolic process that produces pyruvate and energy in the form of adenosine triphosphate (ATP). Once pyruvate is formed as an end product of glycolysis, it is shuttled into the mitochondria, where it is converted to acetyl-CoA by pyruvate dehydrogenase. Acetyl-CoA then enters the TCA cycle to produce additional energy with the aid of the electron transport chain. Since glucose is so rapidly metabolized for energy production and has a limited storage capacity, other energy substrates, such as fat, get stored as triglycerides due to our body’s virtually infinite fat storage capacity. When a sufficient source of carbohydrates is not available, the body adap Continue reading >>

How To Get Your Body Into Ketosis: 6 Simple Tips

How To Get Your Body Into Ketosis: 6 Simple Tips

If you’re looking to burn fat off your body fast, then you need your body to get into ketosis. This is the basis behind the ketogenic diet. Most of us have bodies that are sugar burners. This isn’t a bad thing. Most of our diets lead to our body wanting to burn sugars first anyway. That’s the problem, though, our diets. A lot of the foods we eat on a daily basis are going to convert into glucose when they are processed by our bodies. This leads to our bodies looking at the glucose as its main source of energy instead of fat. When your body is using sugar for energy, it’s burning that instead of any fat you may be wanting to get rid of. If you can get your body into ketosis, it will become a fat burner instead of a sugar burner. This means that your body will look to burn fat for energy instead of something else. You will then begin to start shedding fat off your body and you’ll begin seeing the pound come off. Getting into ketosis isn’t a very easy task. There is a process that you need to go through. Your body will be making a major change. You’ve probably been a sugar burner your entire life so changing into ketosis will be a giant leap. Tips to Get into Ketosis Below are going to tips on how to get your body into ketosis. They are proven tips so if you follow them, you should be a fat burner in no time. If you’re looking for more guidelines on how to change your body, look at this 28-day challenge that is guaranteed to help you drop fat and make your body a fat-burning machine. Lower Carb Intake One of the first things you need to do if you want to get into ketosis is to bring your carb intake way down. Not just a little bit, you need to have a significant drop in the amount of carbs you eat daily. This is by far the most important tip when it comes t Continue reading >>

Is Keto Healthy? Ketosis Vs Ketoacidosis

Is Keto Healthy? Ketosis Vs Ketoacidosis

Is Keto Healthy? Ketosis vs Ketoacidosis When looking at a ketogenic diet and ketosis, it’s common for some people to confuse the process with a harmful, more extreme version of this state known as diabetic ketoacidosis. But there are a lot of misconceptions out there about ketosis vs ketoacidosis, and it’s time to shed some light on the subject by looking at the (very big) differences between the two. An Overview of Ketosis A ketogenic, or keto, diet is centered around the process of ketosis, so it’s important to understand exactly what ketosis is first before we get into whether or not it’s safe (spoiler: it is): Ketosis is a metabolic state where the body is primarily using fat for energy instead of carbohydrates. Burning carbohydrates (glucose) for energy is the default function of the body, so if glucose is available, the body will use that first. But during ketosis, the body is using ketones instead of glucose. This is an amazing survival adaptation by the body for handling periods of famine or fasting, extreme exercise, or anything else that leaves the body without enough glucose for fuel. Those eating a ketogenic diet purposely limit their carb intake (usually between 20 and 50 grams per day) to facilitate this response. That’s why the keto diet focuses on very low carb intake, moderate to low protein intake, and high intakes of dietary fats. Lower protein is important because it prevents the body from pulling your lean muscle mass for energy and instead turns to fat. Ketone bodies are released during ketosis and are created by the liver from fatty acids. These ketones are then used by the body to power all of its biggest organs, including the brain, and they have many benefits for the body we’ll get into later. But first, let’s address a common mi Continue reading >>

Ketosis Breath: Causes & Solutions For Bad Breath

Ketosis Breath: Causes & Solutions For Bad Breath

Ultra-low carb diets have grown in popularity over recent years. These so-called “keto diets” aim to facilitate rapid weight loss, through the consumption of minimal carbohydrates. Keto diets have become understandably popular on account of their rapid results, together with the practical benefits of consuming healthy volumes of the right foods, making hunger less of a problem than on more typical calorie-controlled diets. However keto diets are not without their issues, and one of the most common complaints comes in the form of “ketosis breath”. Quite simply many individuals making use of very low carb diets suffer from pungent and unpleasant breath. The question is what can be done to counteract such a problem? The Cause of Ketosis Breath In order to learn how to get rid of keto breath, we first need to understand why breath can smell under such a regime. As it turns out there are two potential reasons(1), both of which can operate independently, or in conjunction. Ketone Release The most typical source of energy used by the body is glucose. This is typically derived from carbohydrates, where the digestive system breaks down complex sugars into simple glucose molecules. On very low carb diets, however, the body is unable to utilize such a fuel. Instead, the liver utilizes the fat present in the body as an energy source, producing “ketones” in the process(2). This is known as “ketosis” – and is the process from where keto diets get their unusual name. These ketone bodies come in three common forms; acetoacetate, beta-hydroxybutyrate and acetone(3). In large quantities they are removed from the body in the urine or through exhalation. Ketones can have quite a characteristic smell; they often make the dieter’s breath smell quite sweet and fruity, quit Continue reading >>

7 Tips To Get Into Ketosis

7 Tips To Get Into Ketosis

And convert fat into energy. By Franziska Spritzler, RD, CDE Ketosis is a normal metabolic process that provides several health benefits. During ketosis, your body converts fat into compounds known as ketones and begins using them as its main source of energy. Studies have found that diets that promote ketosis are highly beneficial for weight loss, due in part to their appetite-suppressing effects. Emerging research suggests that ketosis may also be helpful for type 2 diabetes and neurological disorders, among other conditions. That being said, achieving a state of ketosis can take some work and planning. It’s not just as simple as cutting carbs. Here are 7 effective tips to get into ketosis. 1. Minimize Your Carb Consumption Eating a very low-carb diet is by far the most important factor in achieving ketosis. Normally, your cells use glucose, or sugar, as their main source of fuel. However, most of your cells can also use other fuel sources. This includes fatty acids, as well as ketones, which are also known as ketone bodies. Your body stores glucose in your liver and muscles in the form of glycogen. When carb intake is very low, glycogen stores are reduced and levels of the hormone insulin decline. This allows fatty acids to be released from fat stores in your body. Your liver converts some of these fatty acids into the ketone bodies acetone, acetoacetate and beta-hydroxybutyrate. These ketones can be used as fuel by portions of the brain. The level of carb restriction needed to induce ketosis is somewhat individualized. Some people need to limit net carbs (total carbs minus fiber) to 20 grams per day, while others can achieve ketosis while eating twice this amount or more. For this reason, the Atkins diet specifies that carbs be restricted to 20 or fewer grams per Continue reading >>

Bhb Salts - Get Into Ketosis With Betahydroxybutryate

Bhb Salts - Get Into Ketosis With Betahydroxybutryate

Ketogenic diets have been a popular way to lose body fat. Arguably effective, they can be traced back to at least the 1920s. The use of Click here to order now. This situation is observed in both normal and abnormal pathological states, such as fasting and high fat/low carbohydrate dieting (e.g., an Atkin's type diet). These dietary situations eventually lead to an over production of something called "Ketone Bodies" (KB) of which there are three variants - acetoacetate, ?-hydroxybutyrate, and acetone via a process which occurs primarily in the mitochondria of the liver and is known as "ketogenesis" (Prostaglandins Leukot Essent Fatty Acids 2004;70: 243-251). The principal KB that the liver produces is acetoacetate. However, somewhat surprisingly, the principle ketone found in the plasma is actually ?-hydroxybutyrate (BHB). Although if we want to get picky about it, technically BHB is not really a KB because the ketone functional group on BHB has been converted to a hydroxyl group. But it essentially functions like a ketone so If you eat a normal diet with more than (about) 50g/day of carbs, the liver produces very little in the way of ketone bodies and the small amount that it does produce is rapidly metabolized by skeletal and cardiac muscle. When the liver is coaxed into "overproduction" of ketone bodies, they accumulate in the blood at above normal levels obviously, which leads to ketosis (ketonemia and ketonuria the ability for us to detect KB's in blood plasma and urine). As a side note, one KB can be detected in the breath of people in ketosis (the "bad breath" that is often associated with people who are on high fat/low carb diets). This particular ketone body is actually the acetone moiety. In a normal state, the amount of ketone bodies in the blood is quite low Continue reading >>

Caprylic Acid (c8): Blood Ketones Impact And C8 Products

Caprylic Acid (c8): Blood Ketones Impact And C8 Products

Fatty acids come in two forms: saturated and unsaturated. Caprylic acid is a saturated fatty acid. Chemical classification of saturated fatty acids looks at how many carbon atoms are found in the hydrocarbon chain: Less than 6 carbons denotes short-chain fatty acids (SCTs) 6-12 carbons denotes medium-chain fatty acids (MCTs); more than 12 carbons denotes long-chain fatty acids (LCTs); and more than 22 carbons denotes very long-chain fatty acids. Caprylic acid (C8) has 8 carbons and it falls into the MCT category. For this reason it is often called C8 MCT. You find C8 MCT in food products like coconut, palm and butter. C8 MCT has fewer carbons (8 carbons) compared to capric acid (C10) and lauric acid (C12). This is the reason why it has a better ketone producing profile compared to the longer carbon MCTs. C8 MCT products come from palm and coconut oils. Removing the other fatty acids leaves the pure C8 MCT. The result is an oil composed of only caprylic acid. Typical Fatty Acid Composition of Foods Containing MCTs Note: Values in chart are averages for food type. Different farming leads to different fatty acid make-up of the above. E.g. Grass-fed cows tend to make butter with higher MCT content. C6, Caproic acid is the lowest carbon MCT. It is more effective at raising ketone levels than C8. This is due to its lower carbon number. Research shows that it induces higher ketone levels in animals than the other MCT oils. Right now, C6 MCT oil is not available. C6 is generally excluded from MCT oil because it is such a small component in palm and coconut oil products. Unlike C8, high quantities are not found in coconut and palm oils. Instead, C6 is present in various animal fats. 1 What is & What Isnt Caprylic Acid? Clearing Up Naming Confusion Several different names are co Continue reading >>

Acidbase Safety During The Course Of A Very Low-calorie-ketogenic Diet

Acidbase Safety During The Course Of A Very Low-calorie-ketogenic Diet

, Volume 58, Issue1 , pp 8190 | Cite as Acidbase safety during the course of a very low-calorie-ketogenic diet Very low-calorie ketogenic (VLCK) diets have been consistently shown to be an effective obesity treatment, but the current evidence for its acid-base safety is limited. The aim of the current work was to evaluate the acid-base status of obese patients during the course of a VLCK diet. Twenty obese participants undertook a VLCK diet for 4 months. Anthropometric and biochemical parameters, and venous blood gases were obtained on four subsequent visits: visit C-1 (baseline); visit C-2, (1-2 months); maximum ketosis; visit C-3 (2-3 months), ketosis declining; and visit C-4 at 4 months, no ketosis. Results were compared with 51 patients that had an episode of diabetic ketoacidosis as well as with a group that underwent a similar VLCK diet in real life conditions of treatment. Visit C1 blood pH (7.37 0.03); plasma bicarbonate (24.7 2.5 mmol/l); plasma glucose (96.0 11.7 mg/l) as well as anion gap or osmolarity were not statistically modified at four months after a total weight reduction of 20.7 kg in average and were within the normal range throughout the study. Even at the point of maximum ketosis all variables measured were always far from the cut-off points established to diabetic ketoacidosis. During the course of a VLCK diet there were no clinically or statistically significant changes in glucose, blood pH, anion gap and plasma bicarbonate. Hence the VLCK diet can be considered as a safe nutritional intervention for the treatment of obesity in terms of acid-base equilibrium. Ketogenic dietVery low-energy dietObesityKetosisAcidbase safetyAcidosis Diego Gomez-Arbelaez and Ana B. Crujeiras contributed equally to this work. In recent decades the prevalence of obesi Continue reading >>

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