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8.4 Sodium Bicarbonate Intracellular Acidosis

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Md51 - Anaesthesia_mcq

MD51 [Jul01] An intravenous infusion of 8.4% sodium bicarbonate to a healthy adult maycause:A. HypotonicityB. Intracellular AcidosisC. Ionized HypercalcaemiaD.?Respiratory AlkalosisE. Rebound Metabolic AcidosisMD51b [Feb04] BicarbonateA. Complications include intracellular acidosisB. 100ml of 8.4% NaCO3 has 200 milliosmolesC.? Aug15 108. Side effect 8.4% NaHCO3 administration A. Intracellular acidosisB. Rebound metabolic acidosisC. ... Other options were easy to rule out =============================================================================================================== Brandis p38 - almost word for word (is that allowed?) 8.4% NaHCO3 is a one molar solution because the molecular weight of NaHCO3 is 84 = 84g/L = 8.4g/100mls.But each molecule of NaHCO3 dissociates into 2 particles in solution so the osmolality is double the molality. ie 2 osmoles/kg = 2000mOsm/kg = about 7 times the plasma osmolality. 100mls of the solution would then have 200 mOsm. The ECF HCO3 will cause decrease in H+ concentration. I think this then causes H+ to move out of the cells and K+ to move in. If this is true, B would also be incorrect. Don't know about C,D,E can some smart person help me? R Continue reading >>

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  1. Sonomas Mom

    > Ketone and urine strips

    Hello, can someone tell me about using urine strips for testing for ketones? My vet has never mentioned this to me and I see some posters referring to it but I can't find any procedure or table of measurements (normal and abnormal). My Sonoma is still having difficulties being regulated. I have found out that her Lysodrene dosing was getting to her digestive system and causing her stomach upset, which gave her insulin overdose. Now she is running high again on blood glucose levels, and I am worried that she has ketones but don't know how to test for it! Thank you to anyone who can tell me about this. I am able to test BG at home pretty well now. But I need to find out about her ketones in case she is ill from high BG levels. --Karin

  2. Patty

    Here's a picture of the box from Walgreens website:
    http://img.walgreens.com/dbimagecache/30193288050_450x450_a.jpg
    They are a dipstick you can use to test for the level of ketones if they are present with high blood sugar. Anything more than trace warrants a trip to the vet immediately.
    You can catch your dog's urine in a cup and dip it or some hold it in their urine stream. Then match the color to the chart on the bottle after 15 seconds.

  3. Patty

    Here's some additional information with an example of the color chart on the bottle you match the strip to:
    http://diabetesindogs.wikia.com/wiki/Ketones

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Sodium Bicarbonate

Treat acidosis with ventilation and perfusion Bicarbonate has not been shown to improve survival Bicarbonate may transiently depress CV parameters Bicarbonate 4.2% (0.5 meq/ml in 10 ml ampule) Bicarbonate 8.4% (1 meq/ml in 50 ml prefilled syringe) Equivalents of Sodium Bicarbonate (NaHCO3) Standard bicarb ampule is 50 meq in 50 ml Equivalent to 8.4 grams/dl or 4.2 grams/50 ml One ampule = 50 meq = 4.2 grams = 50 mmoles Do not use 8.4% in child under 3 months old Bicarbonate 8.4% is hyperosmolar (2000 mosm/L) Intraventricular bleeding risk in Preterm Infant Use in Child over 3 months old and adults Sodium Bicarbonate 8.4%: 1 amp (50 meq or 50 mmol) Base actual dosing on standard pharmacology texts IV infusion must be slow even in emergency Initial Dose: 1 meq/kg IV or IO over 1-2 minutes Additional Dose: 0.5 meq/kg IV or IO every 10 minutes Base repeat dosages on Arterial Blood Gas Continuous Infusion: 5% bicarbonate (297.5 meq/500ml) VI. Dosing: Adults for Urine Alkalinization Irrigate IV or IO tubing with Normal Saline Irrigate before and after bicarbonate infusion Intracranial Hemorrhage in newborns (hyperosmolality) Use only 4.2% bicarbonate in under age 3 months Images: Relate Continue reading >>

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  1. Teko1

    Eating Correctly.. still high blood sugar

    Hi Guys
    Im new and first off no clue why my profile pic is a black square. Anyway, I've been eating low carb with low carb veggies and protein. Im very frustrated my a1c has been 6.9. Even after i eat a low carb meal if Im lucky I get a readying of 160. Im back on Metformin 2 times a day. I saw the biggest lose of weight and stable bloodsugar 5.3 on Victoza but its very expensive. I exercise and am trying to eat healthy and lose about 25 lbs. And nothing! Ive been doing this for about 6 months.
    When I went on 500 calories a day with the supervision of a doctor I lost 30 and my blood sugar was about 110. But as soon as I stopped that it went back up. Any suggestion would be helpful. I don't want to starve myself. I am eating whole foods mainly veggies. I also had graves disease so have no thyroid.

  2. WASHED OUT

    First off your hormones can and will cause things in the body to go haywire. I hope you are on supplement medication that helps to balance your thyroid problem. Second it can take many months of low carb eating to just get rid of the fat in your liver which is released daily as glucose. The liver stores this supply and causes the dawn phenomenon or higher morning numbers and elevates it throughout the day. When that storage is used up to a point that should improve your glucose control. Just be patient and keep on your diet, most of us have enough body and liver fat stored to keep you from actually starving for quite a long time. That doesn't mean you won't be hungry and want to eat. Even fat people get hungry even though the body doesn't need to eat for energy. The body wants to continue to store energy from food rather than use what is already stored. That stored energy can only be used when you force its use by placing your body in the position of not being able to get the energy from foods you eat. Here is a video of Butter Bob Briggs explaining why, Fat people are always hungry.
    https://www.youtube.com/watch?v=wJhNnbRHCbE
    Another from Dr Jason Fung :
    https://www.youtube.com/watch?v=dimP7IdM2Og

  3. Lillymarie

    Hi washed out I'm new diabetic I don't take meds they make me I'll so i'm eating properly but u said it take months to get u r liver straighten out thank u I have been confused about my numbers they high in the morning and I didn't eat anything the nite before it seems like I can't eat much or the numbers go up can u help thanks again lillymarie

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This is another in my how to series of making things. In this video I show you how to make a water ionization alkalization water unit using simple parts found around the house for around $20 to $30. I did this unit for my health, and to help me clean up 48 years of too many burgers and pizza, also to help me clean the fluoride and chlorine that many cities are putting into the public drinking water systems. I have been drinking the water I made in this unit for over a few weeks, with no harmful effects what so ever, I have however felt better, have more energy, and just a few days. After I started drinking my water I was able to cut my grass and still felt fine, where before I was dead, heck at one point I had to lay in my driveway to rest before I could get cleaned up. This video is intended for educational purposes only. So if you do decide to build one please do so at your own risk. The water made in this unit will result in a high PH ionized alkalized water which is said to balance the high acidic levels of your body. Note to date I do not own a digital ORP or PH level meter so I did the best I could with a chemical test unit I own. I advise anybody building one to purchase these items to get an accurate result of your water levels. Ok Ed, but what does PH and ORP mean? In simple terms PH = acid/alkaline balance = ionizing = O.R.P. (oxidation reduction potential) This is saying that when there are more H+ ions in water than OH- ions, it will read as acidic. When there are more OH- than H+, it's alkaline water. So acid or alkaline liquid is measured as pH, and pH is a measure of hydrogen ions (atoms).The more H+ in a liquid, the more 'acidic'. The more OH-, the more alkaline. What is a good level then? The fact is, most water ionizers will have an ORP reading of -300 to -600 at the 9.5 pH level most often used for drinking, but I have read that the body is not able to process anything over -350, and as the ORP goes to a stronger negative reading than -350 the body isn't able to process the excess. Drinking ionized water throughout the day, at any negative ORP level, gives the body a steady supply of antioxidants -- and minerals -- and hydration, so do not freak out if your water is at a -500 ORP. What is the reason then for drinking alkaline water? Some are reverse aging, more energy, there are too many to list, but the answer is out there on the internet please do the research. Lets just say our body is overloaded with acid type foods like burgers, beer, and soda, it needs help or it starts to rob bones and teeth, and yes, we actually erode our own skeleton to feed our acid habit. It can lead to gout which is painful I'll tell you what. Alkaline water helps to reduce the acid and help the body to balance, but reducing the burgers and beer should be the first step. Remember blood is 7.35 to 7.45 PH.

Efficient Extra- And Intracellular Alkalinization Improves Cardiovascular Functions In Severe Lactic Acidosis Induced By Hemorrhagic Shock | Anesthesiology | Asa Publications

Efficient Extra- and Intracellular Alkalinization Improves Cardiovascular Functions in Severe Lactic Acidosis Induced by Hemorrhagic Shock From the CHU Nancy, Service de Ranimation Mdicale Brabois, Pole Cardiovasculaire et Ranimation Mdicale, Hpital Brabois, Vandoeuvre les Nancy, France; Institut National de la Sant Et de la Recherche Mdicale (INSERM) U1116, Equipe 2, Facult de Mdecine, Vandoeuvre les Nancy, France; Universit de Lorraine, Nancy, France (A.K., N.D., and B.L.); INSERM U1116, Equipe 2, Facult de Mdecine, Vandoeuvre les Nancy, France; Universit de Lorraine, Nancy, France (N.S., K.I., and C.S.); and Critallographie, Rsonnance Magntique et Modlisation (CRM2), Unit Mdicale de Recherche (UMR), Centre National de la Recherche Scientifique (CNRS), Institut Jean Barriol, Facult des Sciences et Technologies, Vandoeuvre les Nancy, France; Universit de Lorraine, Nancy, France (J.-M.E. and S.L.). From the CHU Nancy, Service de Ranimation Mdicale Brabois, Pole Cardiovasculaire et Ranimation Mdicale, Hpital Brabois, Vandoeuvre les Nancy, France; Institut National de la Sant Et de la Recherche Mdicale (INSERM) U1116, Equipe 2, Facult de Mdecine, Vandoeuvre les Nancy, France; Univer Continue reading >>

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  1. danielcruit

    What if I did 100g/day, or 50g/day?
    I'm trying to do this with my partner, and just due to life situation, we don't really have the ability to track religiously what we eat, and staying under 20g is not really possible, for reasons I don't want to get into now. What I'm interested in is simply whether weight loss will still occur at 100g or 50g/day, just more slowly than under 20g, or if we won't lose any weight at all.
    I'm also confused about calories- I'm really a beginner to this, but I was lead to believe that calories didn't matter, only how much carbs you ate, but I see people on this sub all the time asking "how many calories are you eating a day?" to people who say that they are having trouble losing weight on keto.
    Thanks so much for any insight, my understanding of this is really limited.

  2. anbeav

    Ketosis != weight loss
    Ketosis works for many because it makes eating at a deficit feel easier but it's not required for weight loss.
    Also most at less than 100 grams/day are transiently in ketosis.
    If you eat fewer calories than you need at 100 or 50 gram carb intake, you will lose weight. People lose weight eating at much higher carb intake. Keto is not the only way to lose weight (caveat: insulin resistance complicates this situation)
    Calories aren't all that matters, but they matter. For some they can achieve a caloric deficit eating to satiety, many others cannot and need to count calories. If you're not eating in a deficit, you will not lose weight. Calories mater.

  3. IRiseFromTheAshes

    I've never understood why carbs are limited to 0-50g/day, with emphasis of eating under 30g, if being under 100g will still keep you at some level of ketosis. I find it frustrating at times having to limit my vegetable intake of all things simply because I require a lot of calories / day (sometimes close to 4000), which means that proportionally I would have say, 40g of carbs from vegetable instead of 20g from someone eating 2000 calories.

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