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Which Is The Fastest Acting Insulin?

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The fourth episode of Insulin TV focuses on the appropriate use of rapid-acting or ultra-rapid-acting insulins for postprandial glucose control. View the entire series here: http://bit.ly/2lhzh0u

Bolus Insulins (short-acting And Rapid-acting)

Who? Short-acting (Regular) and rapid-acting insulins (Aspart, Lispro, Glulisine) are recommended for patients with type 1, type 2, or gestational diabetes. They may also be used in other types of diabetes. Persons with type 1 diabetes often use insulin regular or rapid-acting insulin in conjunction with intermediate-acting or long acting insulins. Persons with type 2 diabetes often use insulin regular or rapid-acting insulin in conjunction with intermediate or long acting insulin or with oral medications. Women with gestational diabetes sometimes use insulin regular or rapid-acting insulins alone or in conjunction with intermediate-acting insulin. What? Injections are given under the skin. Also suitable for insulin pumps. Rapid-acting insulins can be injected with a traditional syringe and needle, or with a disposable pen that has been prefilled with up to 300 U of insulin. Most patients tend to prefer pens though while convenient, may be expensive. Pens are not available for insulin regular. Three common rapid-acting insulins are: Aspart (marketed as NovoLog and the NovoLog FlexPen) Lispro (marketed as Humalog and the Humalog KwikPen) Glulisine (marketed as Apidra and the Apidra Continue reading >>

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  1. kraftypixie

    Oral drugs besides Metformin

    I'm not sure if my doctor or NP will want to start me on oral meds at our next appt, but I wanted to ask ahead of time, what oral meds do those take who can't tolerate Metformin? I've tried it & had a severe adverse reaction, so it's not going to be considered. Do any others help in any way with weight loss? Please share your knowledge. Thanks.

  2. jwags

    Krafty,
    The only drug I know that helps with weight loss is Byetta. Here is a link to Blood Sugar 101, drug page. It may help
    www.phlaunt.com/diabetes/17977284.php

  3. kraftypixie

    Thanks for that, but I'm afraid with the gastro issues I have that Byetta, with it's gastro upset side effects won't be considered. I was really hoping to get input from T2's that are actually taking oral drugs other than Metformin- what they are, what they do, how well they do or don't work, etc.

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U.S. FDA approves Novo Nordisk fast-acting insulin Fiasp (Audio-Video version for people with limited hearing or vision) The full version of the news is available on http://newsgra.com/english/health/432...

Fast-acting Insulin, Fiasp, Gets Fda Approval

Recently, the U.S. Food and Drug Administration approved Novo Nordisk’s latest fast-acting insulin, Fiasp, for treatment use by adults with diabetes. The move makes available a product that should allow those with T1D to better meet their target A1C levels by controlling post-meal blood sugar spikes. Fiasp, which is a fast-acting insulin asparte, is designed for dosing at the start of a meal or within 20 minutes of beginning to eat. The insulin registers in the blood stream as quickly as two and a half minutes after application. “Generally individuals are well controlled in long insulin,” said Dr. Todd Hobbs, Novo Nordisk’s Chief Medical Officer for North America. “But being able to hold down and keep the meal excursions from rising is going to have an effect on A1C. When individuals get close to their A1C goals — hit seven or eight — but can’t quite get over the hump, most of the time the barrier is meals.” Fiap grew out of the company’s previous fast-acting insulin product, NovoLog. With Fiasp the company improved the speed of initial insulin absorption rates by adding niacinamide (vitamin B3). “With Fiasp we’ve built on the insulin aspart molecule to crea Continue reading >>

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  1. RightWingWacko58

    I just returned from a trip to Canada. Across from my hotel was a Shoppers Drug Mart so I went inside. I had been told that insulin was a lot cheaper in Canada and is available without a prescription.
    To make a long story short: 5 Pens of Lantis $113 Canadian 5 Pens of Humalog $65 Canadian.
    For those of us currently lacking insurance Both these retail for about $476 US each at local pharmacies here in Washington. $178 Canadian works out to about $124 US.
    I should have purchased several boxes, but I was worried about getting it back home. There was no issue at the border when returning home, but I suppose there might have been had I purchased several boxes.
    It will be nice to get back to using Modern Insulin again! Paid for the entire trip with the insulin savings... and then some.
    Fortunately for me, It's a fairly close drive, so I am seeing more trips to our northern neighbors while I work out my Insurance issues.

  2. SisterCole

    You can get bottles of humalog from Walmart here in Canada for 38.00 without a script necessary - its the only way I've been able to afford my insulin as I have no insurance (i'm canadian).

  3. QuietLotus

    Holy cow. As an American who has paid almost $300 for a vial in the past, I suddenly feel like there's something very wrong with my reality.

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FDA approves Novo Nordisk fast-acting insulin Fiasp (Audio-Video version for people with limited hearing or vision) The full version of the news is available on http://newsgra.com/english/health/433...

Fda Approves New Fast-acting Mealtime Insulin

Officials with the FDA have approved fast-acting insulin aspart (Fiasp, Novo Nordisk) for the treatment of adults with diabetes. Fiasp is a fast-acting mealtime insulin designed for individuals in need of improved overall glucose control. Fiasp, a formulation of insulin aspart, was developed to more closely match the physiological insulin mealtime response of an individual with diabetes. Vitamin B3 (niacinamide) and a naturally occurring amino acid (L-Arginine) were added to increase the speed of absorption and for stability, respectively. The approval is based on clinical trials that demonstrated Fiasp’s clinically relevant improvement in long-term glucose level. The trial researchers noted comparable overall rate of severe or blood sugar confirmed hypoglycemia between Fiasp and aspart. The phase 3 clinical program included 4 trials with more than 2100 individuals with type 1 and type 2 diabetes. According to data presented recently at the 53rd European Association for the Study of Diabetes Annual Meeting, in the onset 1 trial, Fiasp was compared to conventional insulin aspart in type 1 diabetes over a 52-week study, split in two 26-week treatment periods. Over the 52-week perio Continue reading >>

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Popular Questions

  1. daisy707

    Switching Insulin: Novolog/Lantus to Novolin R & Novolin N?

    Hi all! It's been a while but I have a question that I'd like some insight on!
    I know it's as simple as seeing my doc and asking her, but I can't get in right now, and not sure if I can before I might lose my insurance coverage. (just weighing my options so I have a back up plan for insulin)
    Anyway, I am taking Novolog and Lantus and I have a friend (Type 1) who switched from the exact same ones to Novolin R and Novolin N, without any issues. My friend told me that I can get them without a prescription at Walmart for about $25 each. So knowing that I have this option if my plan changes or I get cut off, helps ease my fears of not being able to afford any insulin at all, but I am wondering if anyone else has switched to these and how they did?
    I trust her experience and info but wanted to hear others experiences as well if there are any! When I was first diagnosed I was on Novolin R and Lantus, so I know the Novolin R will work for meals (still not sure how different the timing of the insulin will affect me now) but I'm not sure about the Novolin N, it being a long acting and having no experience taking another type.
    Any info will be helpful! I do research outside of this site but it is my go to for questions! Thanks for the help!!

  2. coravh

    I Daisy. I think you'll find very few people who have switched to those insulins. Most have switched from. That being said, most of the long timers have used them. I always found the N to be kind of unreliable and peaky. And especially when you've taken it in the morning and it's peaked at about dinner, your I:C ratios kind of go out the window. You will have to test quite a bit and find out how these insulins work for you. I would usually get an R peak at about 4 hours, so if I took it combined with my N inthe morning, it pretty much covered my lunch (wasn't a big breakfast eater anyway). And then dinner was covered roughly as I said above and then my dp was actually handled quite nicely by my bedtime shot of N. At one point, before the intro of lantus, I did have 1 bottle of humalog on hand for the rare days I ate breakfast, for an extra shot at dinner or to bring down a high because the R took too long for me.
    Best of luck to you. Hope your insurance stays intact - I wouldn't want to have to switch back to those babys.
    Cora
    eta: my insulin needs were always 'off' the official ratios, so the pre-mixed insulins were a no-go for me.

  3. 1986

    Novolog is a much faster insulin than Novolin R and Lantus lasts 2 times longer than Novolin R, And Novolin R has a very pronounced Peek that would cause lows if BG not watched closely.
    you can see the effect of different insulins hear
    https://provider.ghc.org/open/caring...thActivity.pdf

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