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Which Insulins Are Cloudy In Appearance

What Does Cloudy Insulin Mean?

What Does Cloudy Insulin Mean?

Insulin can change when stored, says the American Diabetes Association (ADA). Many factors speed up the change, including warm temperatures and shaking the insulin bottle. That’s why the ADA recommends that you avoid carrying your insulin in your pocket, especially if you are an active person. Keep it in a refrigerator, cupboard, purse, briefcase or backpack, and protect it from heat and motion. If regular insulin becomes cloudy, throw it away, says the ADA. It has lost its effectiveness, and won’t keep your blood sugar from getting too high. If your insulin is a mix of regular and NPH or ultralente insulins, you may be getting NPH or ultralente in the bottle of regular insulin. This, too, will make it cloudy. If in doubt, discard the old bottle and replace it with a new one. Reprinted from 101 Tips for Improving Your Blood Sugar by the University of New Mexico Diabetes Care Team. Copyright by the American Diabetes Association. Used by permission. All rights reserved. Play Video Play Loaded: 0% Progress: 0% Remaining Time -0:00 This is a modal window. Foreground --- White Black Red Green Blue Yellow Magenta Cyan --- Opaque Semi-Opaque Background --- White Black Red Green Blue Yellow Magenta Cyan --- Opaque Semi-Transparent Transparent Window --- White Black Red Green Blue Yellow Magenta Cyan --- Opaque Semi-Transparent Transparent Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Dropshadow Font Family Default Monospace Serif Proportional Serif Monospace Sans-Serif Proportional Sans-Serif Casual Script Small Caps Defaults Done Connect with Us Get more healthy food for thought – check out our posts on Health Bistro and Lifescript TV videos on YouTube. Plus, join the fun and conversation on Google+, Facebook, Twitter, Continue reading >>

Insulin Treatment For Diabetes

Insulin Treatment For Diabetes

People with type 1 diabetes are unable to produce enough insulin to regulate the glucose (sugar) levels within their blood, so they need to take insulin to manage their diabetes. Some people with type 2 diabetes and gestational diabetes (diabetes that develops during pregnancy) may also need insulin to control their blood sugar levels. There are a variety of types of insulin and ways to give it, including injections, pens and pumps. Your doctor and diabetes educator can recommend the most suitable type of insulin and delivery device for you. Types of insulin There are different types of insulin available to manage diabetes. These days, most types of insulin are synthetic (created in a laboratory), but there are some that are extracted from the pancreas of animals. Types of insulin vary, according to: how quickly they take effect; how long their effect lasts; and when they reach their peak, in terms of ability to lower blood-glucose levels. Ultra-short-acting insulin Ultra-short-acting (also called very-short-acting or rapid-acting) insulin starts to work about 15 minutes after being injected, peaks after about 1-2 hours, and lasts for about 4-5 hours. This type of insulin is injected immediately before meal times and is also used in insulin pumps. Types of ultra-short-acting insulin include: insulin glulisine (brand name Apidra); insulin lispro (Humalog); and insulin aspart (NovoRapid). These are all synthetic copies (analogues) of human insulin and are clear in appearance. Short-acting insulin Short-acting insulin (insulin neutral) starts to work about half an hour after being injected, peaks from between 3 and 5 hours, and lasts for about 6-8 hours. Short-acting insulin is given 20-30 minutes before a meal. It is clear in appearance. Types of short-acting neutral insu Continue reading >>

Nph Insulin

Nph Insulin

NPH insulin, also known as isophane insulin, is an intermediate–acting insulin given to help control blood sugar levels in people with diabetes.[3] It is used by injection under the skin once to twice a day.[1] Onset of effects is typically in 90 minutes and they last for 24 hours.[3] Versions are available that come premixed with a short–acting insulin, such as regular insulin.[2] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] NPH insulin is made by mixing regular insulin and protamine in exact proportions with zinc and phenol such that a neutral-pH is maintained and crystals form.[1] There are human and pig insulin based versions.[1] Protamine insulin was first created in 1936 and NPH insulin in 1946.[1] It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[4] The wholesale cost in the developing world is about 2.23 to 10.35 USD per 1,000 iu of NPH insulin.[5] In the United Kingdom 1,000 iu of NPH insulin costs the NHS 7.48 pounds while in the United States this amount costs about 134.00 USD.[2][6] Chemistry[edit] NPH insulin is cloudy and has an onset of 1–4 hours. Its peak is 6–10 hours and its duration is about 10–16 hours. History[edit] Hans Christian Hagedorn (1888–1971) and August Krogh (1874–1949) obtained the rights for insulin from Banting and Best in Toronto, Canada. In 1923 they formed Nordisk Insulin laboratorium, and in 1926 with August Kongsted he obtained a Danish Royal Charter as a non-profit foundation. In 1936, Hagedorn and B. Norman Jensen discovered that the effects of injecte Continue reading >>

Humalog Kwikpens

Humalog Kwikpens

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet is designed to provide you with answers to some common questions about these medicines. It does not contain all the available information and does not take the place of talking with your doctor. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMALOG and its use that you should be aware of. All medicines have risks and benefits. Your doctor has more information about these medicines than is contained in this leaflet. Also, your doctor has had the benefit of taking a full and detailed history from you and is in the best position to make an expert judgement to meet your individual needs. If you have any concerns about using these medicines, talk to your doctor or pharmacist. What the HUMALOG insulins are used for HUMALOG insulins are used to reduce high blood sugar (glucose) levels in insulin dependent diabetic patients. Diabetes is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. Type 1 diabetes - also called Insulin Dependent Diabetes Mellitus (IDDM). Patients with type 1 diabetes always need insulin to control their blood sugar levels. Type 2 diabetes - also called Non insulin dependent diabetes mellitus (NIDDM). Some patients with type 2 diabetes may also need insulin after initial treatment with diet, exercise an Continue reading >>

Insulin And Diabetes

Insulin And Diabetes

Insulin injections are required when the body produces little or no insulin, as with type 1 diabetes. They are also required for some people with type 2 diabetes when diabetes tablets, together with healthy eating and regular physical activity, are not enough to control blood glucose levels. What is insulin? Insulin is a hormone made by special cells, called beta cells, in the pancreas. When we eat, insulin is released into the blood stream where it helps to move glucose from the food we have eaten into cells to be used as energy. Insulin also helps store excess glucose in the liver. Why must it be injected? While ways of taking insulin by mouth or as a nasal spray are being developed, they are yet to become readily available. Insulin cannot be given in tablet form as the stomach would digest it, just as it digests food. What if I have to go on to insulin? For people with type 2 diabetes, starting on insulin can be a difficult and frightening decision to make. However, the many injection devices and tiny needles available today make injecting insulin much easier than most people imagine. In fact many say that they can feel the finger prick for monitoring blood glucose more than they can feel the needle used to inject insulin. When starting on insulin, your doctor and diabetes educator will help you adjust to the new routine. You may find that even with their help, it may take a while to find exactly the right dose to reduce your blood glucose to acceptable levels and to suit your particular lifestyle. Are there different types of insulin? There are 5 types of insulin ranging from short to long acting as insulin is classified according to how long it works in the body. Some insulins are clear in appearance, others cloudy. Everyone is different and will respond differentl Continue reading >>

Diabetes And Insulin

Diabetes And Insulin

On this page: Diabetes mellitus (diabetes) is a chronic and potentially life-threatening condition where the body loses its ability to produce insulin, or begins to produce or use insulin less efficiently, resulting in blood glucose levels that are too high (hyperglycaemia). Blood glucose levels above the normal range , over time, can damage your eyes, kidneys and nerves, and can also cause heart disease and stroke. An estimated 280 Australians develop diabetes every day. Diabetes is Australia's fastest-growing chronic disease. The main types of diabetes are type 1, type 2, and gestational diabetes. Type 1 diabetes Type 1 diabetes develops when the cells of the pancreas stop producing insulin. Without insulin, glucose cannot enter the cells of the muscles for energy. Instead the glucose rises in the blood causing a person to become extremely unwell. Type 1 diabetes is life threatening if insulin is not replaced, and people need to inject insulin for the rest of their lives. Type 1 diabetes often occurs in children and people under 30 years of age, but it can occur at any age. This condition is not caused by lifestyle factors. Its exact cause is not known but research shows that something in the environment such as the rubella virus can trigger it in a person that has a genetic risk. The body’s immune system attacks and destroys the beta cells of the pancreas after the person gets a virus because it sees the cells as foreign. Most people diagnosed with type 1 diabetes do not have family members with this condition. For more information about symptoms, visit the Diabetes type 1 fact sheet. Type 2 diabetes Type 2 diabetes develops when the pancreas does not make enough insulin and the insulin that is made does not work as well as it should (also known as insulin resistan Continue reading >>

Humulin N, 100 Units

Humulin N, 100 Units

INFORMATION FOR THE PATIENT WARNINGS THIS LILLY HUMAN INSULIN PRODUCT DIFFERS FROM ANIMAL-SOURCE INSULINS BECAUSE IT IS STRUCTURALLY IDENTICAL TO THE INSULIN PRODUCED BY YOUR BODY'S PANCREAS AND BECAUSE OF ITS UNIQUE MANUFACTURING PROCESS. ANY CHANGE OF INSULIN SHOULD BE MADE CAUTIOUSLY AND ONLY UNDER MEDICAL SUPERVISION. CHANGES IN STRENGTH, MANUFACTURER, TYPE (E.G., REGULAR, NPH, LENTE), SPECIES (BEEF, PORK, BEEF-PORK, HUMAN), OR METHOD OF MANUFACTURE (rDNA VERSUS ANIMAL-SOURCE INSULIN) MAY RESULT IN THE NEED FOR A CHANGE IN DOSAGE. SOME PATIENTS TAKING HUMULIN (HUMAN INSULIN, rDNA ORIGIN) MAY REQUIRE A CHANGE IN DOSAGE FROM THAT USED WITH ANIMAL-SOURCE INSULINS. IF AN ADJUSTMENT IS NEEDED, IT MAY OCCUR WITH THE FIRST DOSE OR DURING THE FIRST SEVERAL WEEKS OR MONTHS. DIABETES Insulin is a hormone produced by the pancreas, a large gland that lies near the stomach. This hormone is necessary for the body's correct use of food, especially sugar. Diabetes occurs when the pancreas does not make enough insulin to meet your body's needs. To control your diabetes, your doctor has prescribed injections of insulin products to keep your blood glucose at a near-normal level. You have been instructed to test your blood and/or your urine regularly for glucose. Studies have shown that some chronic complications of diabetes such as eye disease, kidney disease, and nerve disease can be significantly reduced if the blood sugar is maintained as close to normal as possible. The American Diabetes Association recommends that if your premeal glucose levels are consistently above 140 mg/dL or your hemoglobin A 1c (HbA 1c ) is more than 8%, consult your doctor. A change in your diabetes therapy may be needed. If your blood tests consistently show below-normal glucose levels you should also let Continue reading >>

Difference Between Nph And Regular Insulin

Difference Between Nph And Regular Insulin

NPH vs Regular Insulin Diabetes mellitus is a long-term condition linked with irregularly high levels of glucose or sugar within the blood. It is a cluster of metabolic disorders exemplified by abnormal blood sugar levels due to deficient secretion of insulin and action or both. This disease is typically called diabetes and was first discovered as a disorder linked with sugary urine and an extreme loss of muscle tone way back in the past decades. Increased blood glucose levels, or hyperglycemia, can result in the seeping out of glucose within the urine, thus the expression “sweet urine.” Regularly, blood sugar levels are strictly managed by insulin. Insulin is the hormone secreted by the pancreas which is responsible for lowering the levels of blood glucose. The increase of blood sugar levels are commonly noted as the patient eats. Insulin is then liberated from the pancreas to put the blood sugar levels on a normal level. The patients with diabetes mellitus, with insufficient or absent manufacture of insulin, may have hyperglycemia. The two types of diabetes mellitus are the insulin-dependent type and the non-insulin-dependent type. The characteristic of these two types is described by the terms used to identify them. The non-insulin-dependent types are the patients with minimal insulin production that are augmented by taking oral hyperglycemic agents. On the other hand, the insulin-dependent types are the patients that have the inability to produce insulin with more than 100 mg/dl blood sugar level. The development of such circumstances entails an enduring medical intervention such as insulin administration. Insulin concentrations have different characteristics which gives the patient choices on what to use. Two of these concentrations are the regular and NPH insu Continue reading >>

Insulins - Brand Names

Insulins - Brand Names

Sort Which types of insulin are clear? Which types are cloudy? Three CLEAR (1) rapid-acting (2) short-acting (3) long-acting Three CLOUDY (1) intermediate-acting (2) human mixture (3) analog mixture Which insulin mixtures include insulin analogs? Are they cloudy or clear? (1) insulin lispro protamine 75% / insulin lispro (Humalog Mix 75/25) (2) insulin lispro protamine 50% / insulin lispro 50% (Humalog 50/50) (3) insulin aspart protamine 70% / insulin aspart 30% (NovoLog Mix 70/30) CLOUDY Continue reading >>

Diabetes: Under The Skin Of Diabetes

Diabetes: Under The Skin Of Diabetes

Rita Forde gives an overview of the developments in insulin administration Diabetes mellitus is a complex, multi-system disease, which results in an alteration in the metabolism of carbohydrates, fats and proteins.1 People with type 1 diabetes do not produce insulin and are therefore dependent on an exogenous supply to sustain life. Those with type 2 produce some insulin and are not dependent on an exogenous insulin supply but may, over time, require insulin to maintain adequate blood glucose levels. Whenever insulin therapy is used, it is essential that the dosage is individualised to the particular needs of the person and is balanced with their diet and exercise. Insulin Insulin is obtained from beef or pork pancreas, or is produced chemically by recombinant DNA technology.2 In recent years, insulin analogues have been developed by modifying the amINO acid sequence of the insulin molecule. The duration of action of the various insulin types is used to differentiate them. In Ireland, rapid-acting, short-acting, intermediate-acting and long-acting insulins are available. Bi-phasic insulin, a combination of either rapid- or short-acting insulin and intermediate-acting insulin, is also available. While the insulins from the various companies are not identical, there are similarities between them. The following is an overview of the insulin types and not the specific brands of insulin available. Insulin analogues: These are rapid-acting insulins. Once injected, the insulin onset is almost immediate. The action peaks between one and three hours and the duration of action is between four and five hours.3,4 Short-acting insulin: This is also referred to as soluble insulin. Following subcutaneous injection, these types of insulin take 30 minutes for the onset of action. The pe Continue reading >>

Types Of Insulin

Types Of Insulin

Insulin is always taken by injection using either a small syringe, or an Insulin Pen. Insulin must be stored in a refrigerator although the vial or pen in use can be kept at room temperature. Insulin types Insulin is described as “Rapid-acting”, “Short-acting”. “Intermediate-acting” or “Long-acting”. Rapid and short-acting insulins are described as “Bolus” and are clear in appearance. Intermediate and long-acting insulins are described as Basal and with the exception of Lantus and Levemir are cloudy in appearance. All types of insulin have a delayed onset of their peak activity and different durations of activity. Rapid-acting – These insulins (Novo Rapid, Humalog) act very quickly and only last an hour or two Short-acting – These insulins (Actrapid, Humulin R) take effect after about half an hour and last 3 to 4 hours Intermediate – and long-acting – These insulins (Humulin NPH, Protaphane, Lantus and Levemir) take effect after about an hour and are designed to last “all day” Premixed – These insulins are a mixture of short and intermediate acting insulins and act just like two injections of the separate components taken at the same time. Some 3 ml cartridges contain a mixture of both Short and Long acting insulin, and some short and long acting Insulins may be mixed in a syringe prior to injection. The following three brands of insulin are available in New Zealand. Eli Lilly Novo Nordisk Sanofi Aventis Each brand has several different types with different presentations and durations. Most insulins come in both 3 ml cartridges for use in Insulin pens and 10 ml vials, and are administered with syringes. Storage Your stock of insulin must be stored in a refrigerator between 2 and 8 degrees C. This is normal operating temperature for a do Continue reading >>

Insulin In The Uk

Insulin In The Uk

Tweet Insulin may be a key part of your treatment if you suffer from diabetes. Insulin enables your body to use glucose. Different types of insulin can act very differently in different people. Insulin regime suitable for individual patients are tailored by your diabetes care team. Type or dosage of insulin can be changed if required to meet the individual needs of the patient. Insulin can be packaged in vials (bottles), cartridges or prefilled pens. The vials are used with syringes, whereas the cartridges are used with pen injectors. Prefilled pens are disposable pen injectors, which contain insulin. Prefilled pens are useful for people with dexterity or visual problems. List of insulins The table highlights the various insulin types, their manufacturers, the insulin source and how it's available. It also highlights insulin ranges that have been discontinued. Insulin type Name Manufacturer Type Source Rapid-acting analogue Apidra Sanofi analogue vial & cartridge Apidra Sanofi analogue prefilled pen Humalog Lilly analogue vial & cartridge Humalog Lilly analogue prefilled pen Novorapid Novo Nordisk analogue vial Novorapid Penfill Novo Nordisk analogue cartridge Novorapid Novolet Novo Nordisk analogue prefilled pen Long-acting analogue Lantus Sanofi analogue vial, cartridge & prefilled pen Levemir Novo Nordisk analogue cartridge & prefilled pen Tresiba Novo Nordisk analogue cartridge & prefilled pen Short-acting Human Actrapid Novo Nordisk human vial Actrapid Pen* Novo Nordisk human prefilled pen Actrapid Penfill* Novo Nordisk human cartridge Human Velosulin* Novo Nordisk human vial Pork Actrapid* Novo Nordisk pork vial Humaject S* Lilly human prefilled pen Humulin S Lilly human vial & cartridge Hypurin Bovine Neutral CP Pharmaceuticals beef vial & cartridge Hypurin Porci Continue reading >>

Insulins Are Cloudy In Appearance

Insulins Are Cloudy In Appearance

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Insulin Treatment

Insulin Treatment

Insulin is a hormone made in your pancreas, which lies just behind your stomach. It helps our bodies use glucose for energy. Everyone with Type 1 diabetes and some people with Type 2 diabetes need to take insulin – either by injection or a pump – to control their blood glucose levels (also called blood sugar levels). Injecting insulin Insulin is injected using a syringe and needle, or an insulin pen or needle. The needles used are very small as the insulin only needs to be injected under the skin (subcutaneously) – not into a muscle or vein. Once it's been injected, it soaks into small blood vessels and is taken into the bloodstream. As your confidence grows and you become more relaxed, injections will get easier and soon become second nature. The most frequently used injection sites are the thighs, buttocks and abdomen. You may be able to inject into your upper arms, but check with your diabetes team first as this isn't always suitable. As all these areas cover a wide skin area, you should inject at different sites within each of them. It is important to rotate injection sites, as injecting into the same place can cause a build up of lumps under the skin (also known as lipohypertrophy), which make it harder for your body to absorb and use the insulin properly. The three groups of insulin There are three groups of insulin – animal, human (not from humans but produced synthetically to match human insulin) and analogues (the insulin molecule is like a string of beads; scientists have managed to alter the position of some of these beads to create 'analogues' of insulin). Nowadays, most people use human insulin and insulin analogues, although a small number of people still use animal insulin because they have some evidence that they otherwise lose their awareness of Continue reading >>

Types Of Insulin

Types Of Insulin

Topic Overview Insulin is used to treat people who have diabetes. Each type of insulin acts over a specific amount of time. The amount of time can be affected by exercise, diet, illness, some medicines, stress, the dose, how you take it, or where you inject it. The table below is a general guide. Your results may be different. Insulin strength is usually U-100 (or 100 units of insulin in one milliliter of fluid). Short-acting (regular) insulin is also available in U-500. This is five times more concentrated than U-100 regular insulin. Long-acting insulin (glargine) is also available in U-300. This is three times more concentrated than U-100 long-acting insulin. Be sure to check the concentration of your insulin so you take the right amount. Insulin is made by different companies. Make sure you use the same type of insulin consistently. Types of insulin Type Examples Appearance When it starts to work (onset) The time of greatest effect (peak) How long it lasts (duration) Rapid-acting insulins work over a narrow, more predictable range of time. Because they work quickly, they are used most often at the start of a meal. Rapid-acting insulin acts most like insulin that is produced by the human pancreas. It quickly drops the blood sugar level and works for a short time. If a rapid-acting insulin is used instead of a short-acting insulin at the start of dinner, it may prevent severe drops in blood sugar level in the middle of the night. Apidra (glulisine), Humalog (lispro), Novolog (aspart) Clear 5–30 minutes 30 minutes–3 hours 3–5 hours Rapid-acting insulin also comes in a form that can be inhaled through the mouth. Afrezza (insulin human, inhaled) Contained in a cartridge 10–15 minutes 30–90 minutes 2½–3 hours Short-acting insulins take effect and wear off more Continue reading >>

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