Where Is Insulin Produced

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Endocrine Pancreas

This page outlines information on the pancreas. Several hormones participate in the regulation of carbohydrate metabolism. Four of them are secreted by the cells of the islets of Langerhans in the pancreas: two, insulin and glucagon, with major actions on glucose metabolism and two, somatostatin and pancreatic polypeptide, with modulating actions on insulin and glucagon secretion. Other hormones affecting carbohydrate metabolism include: epinephrine, thyroid hormones, glucocorticoids, and growth hormone. Structure and Function of the Pancreas The pancreas lies inferior to the stomach, in a bend of the duodenum. It is both an endocrine and an exocrine gland. The exocrine functions are concerned with digestion. The endocrine function consists primarily of the secretion of the two major hormones, insulin and glucagon. Four cell types have been identified in the islets, each producing a different hormone with specific actions: * A cells produce glucagon; * B cells produce insulin; * D cells produce somatostatin; and * F or D1 cells produce pancreatic polypeptide. These hormones are all polypeptides. Insulin is secreted only by the B cells whereas the other hormones are also secreted by Continue reading >>

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Popular Questions

  1. ilana

    I was just recently diagnosed with type 1 and I'm taking about 20 units total (12 Lantus and 8 Novolog) per day. I'm curious how much insulin other people with type 1 take and if it's changed much over the years.

    Thanks much!

  2. Kari2

    60 units a day, on average. It's increased over the years. I'm type 1, but believe I have some insulin resistance.

  3. Gerri

    Hi Ilana,
    What other people take is quite variable. Insulin doses are based on weight, activity level, other meds being taken, how many carbs per meal, etc. You can't compare your doses based on other people's. A newly diagnosed T1, who may be still in a honeymoon phase, will take a different amount also.

    Insulin doses usually do change over time.

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