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What Type Of Insulin Can Be Used In An Insulin Pump?

Types Of Insulin For Diabetes Treatment

Types Of Insulin For Diabetes Treatment

Many forms of insulin treat diabetes. They're grouped by how fast they start to work and how long their effects last. The types of insulin include: Rapid-acting Short-acting Intermediate-acting Long-acting Pre-mixed What Type of Insulin Is Best for My Diabetes? Your doctor will work with you to prescribe the type of insulin that's best for you and your diabetes. Making that choice will depend on many things, including: How you respond to insulin. (How long it takes the body to absorb it and how long it remains active varies from person to person.) Lifestyle choices. The type of food you eat, how much alcohol you drink, or how much exercise you get will all affect how your body uses insulin. Your willingness to give yourself multiple injections per day Your age Your goals for managing your blood sugar Afrezza, a rapid-acting inhaled insulin, is FDA-approved for use before meals for both type 1 and type 2 diabetes. The drug peaks in your blood in about 15-20 minutes and it clears your body in 2-3 hours. It must be used along with long-acting insulin in people with type 1 diabetes. The chart below lists the types of injectable insulin with details about onset (the length of time before insulin reaches the bloodstream and begins to lower blood sugar), peak (the time period when it best lowers blood sugar) and duration (how long insulin continues to work). These three things may vary. The final column offers some insight into the "coverage" provided by the different insulin types in relation to mealtime. Type of Insulin & Brand Names Onset Peak Duration Role in Blood Sugar Management Rapid-Acting Lispro (Humalog) 15-30 min. 30-90 min 3-5 hours Rapid-acting insulin covers insulin needs for meals eaten at the same time as the injection. This type of insulin is often used with Continue reading >>

Insulin Pumps

Insulin Pumps

The Dumbest & Smartest Things A Doctor Ever Told Me With increasing frequency, individuals with type 1 diabetes (and, to a lesser extent, type 2 diabetes) are being placed on insulin pump therapy (also called Continuous Subcutaneous Insulin Infusion or CSII for short). Unlike the usual form of intensified management which generally requires injections of insulin between 4 to 6 times per day and uses a combination of rapid or short-acting insulin as well as intermediate-acting insulin or long acting insulin , pump therapy uses only rapid-acting insulin and gives the insulin in tiny doses (called "basal insulin") around the clock. An insulin pump also allows you to give "boluses" (a few extra units of insulin) when you are about to eat. One advantage of insulin pump therapy (compared to giving yourself multiple daily injections of insulin) is that you will likely achieve better blood glucose control with fewer elevated readings and fewer episodes of hypoglycemia. A huge additional benefit is that the great majority of people with diabetes who go on pump therapy LOVE it and would NEVER go back to conventional injections. The most common comment I hear is: "It's so much more convenient. Iwish I had done this sooner!" Note that I do not hear that it is less work (cuz it ain't less work; if anything it's more work). One potential turn off about being on a pump is that you have to wear it around the clock. Sure, that may sound unpleasant, BUT I must say that these words are seldom spoken by actual pump users; it's pretty well only people that haven't yet tried a pump who voice this concern. So, if you are considering pump therapy I'd suggest you mull over the following (I'll mention only major points): Pumps have to be worn around the clock (with brief exceptions). Pumps are Continue reading >>

Type 1 Insulin Pump | Humalog

Type 1 Insulin Pump | Humalog

Humalog (insulin lispro injection) is used to treat people with diabetes for the control of blood sugar. Humalog is used to treat people with diabetes for the control of blood sugar. Humalog Mix75/25(75% insulin lispro protamine suspension and 25% insulin lispro injection) and Humalog Mix50/50(50% insulin lispro protamine suspension and 50% insulin lispro injection) are used to treat adults with diabetes for the control of high blood sugar. Do not take Humalog if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in Humalog. Important Safety Information for Humalog Brand of Insulins What is the most important information I should know about Humalog, Humalog Junior KwikPen, Humalog 200 units/mL KwikPen, Humalog Mix75/25, and Humalog Mix50/50? Do not share your Humalog, Humalog Junior, Humalog Mix75/25, or Humalog Mix50/50 KwikPens, cartridges, reusable pen compatible with Lilly 3 mL cartridges, or syringes with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them. Humalog 200 units/mL KwikPen contains 2 times as much insulin (200 units/mL) in 1 mL as standard insulin (100 units/mL). The Humalog contained in the Humalog U-200 KwikPen should ONLY be injected with the Humalog U-200 KwikPen. Do NOT withdraw Humalog U-200 from the pen using a syringe. It could result in an overdose causing severe low blood sugar which may put your life in danger. Do not change the insulin you use without talking to your healthcare provider. Changes may make you more likely to experience low or high blood sugar. Changes should be made cautiously under the supervision of your healthcare provider. Test your blood sugar levels as your healthcare provider ins Continue reading >>

Using An Insulin Pump

Using An Insulin Pump

NovoLog® has been proven safe and effective for use in insulin pumps in children ages 2 and older with type 1 diabetes and adults with type 1 and type 2 diabetes. Many people with type 1 diabetes use an insulin pump. What is an insulin pump? An insulin pump is a small, programmable, battery-operated device that delivers a steady, measured amount of insulin under your skin. You and your diabetes care team can program your insulin pump to deliver NovoLog® in constant “basal” doses throughout the day and “bolus” doses at mealtime. Insulin pumps may be helpful for people with diabetes who have more than one insulin injection per day, including some people with type 2 diabetes. Pumps provide continuous insulin delivery in small doses, similar to the way the pancreas naturally releases basal insulin. You push a button to release mealtime doses of insulin to cover food. They allow people with diabetes to take their insulin automatically, wherever they happen to be. Benefits of NovoLog® in an insulin pump NovoLog® is a fast-acting insulin that can be used for up to 6 days in a pump before it needs to be changed. The table below shows how often to change NovoLog® in a pump. Please be sure to check the instructions that came with your pump. Pump component Time frame before changing NovoLog® in reservoir Up to 6 days Infusion set and infusion set insertion site Up to 3 days NovoLog® in the pump should be discarded after exposure to temperatures that exceed 98.6ºF. Low rate of clogs in an insulin pump In a clinical study, NovoLog® was found to have a low rate of clogs when used in pumps. That's good news if you are already using, or thinking about using, an insulin pump. NovoLog® remains heat stable in pumps at normal body temperature (up to 98.6°F). This makes N Continue reading >>

Everything You Need To Know About Insulin Pumps

Everything You Need To Know About Insulin Pumps

Everyone needs insulin to live. Insulin is a hormone that helps our bodies use and store the food we eat. People with Type 1 Diabetes no longer make insulin and have to give insulin in order to sustain life. People with Type 2 Diabetes don’t use their own insulin well, and over time can have trouble making enough. So, all people with Type 1 diabetes and some people with Type 2 diabetes need insulin. When people give insulin injections, they may take 1-2 injections of a long acting insulin every day and 3+ injections of rapid acting insulin for meals and snacks. The typical person with Type 1 Diabetes could take anywhere from 4-7+ injections a day. Many people currently give insulin through an insulin pen or a syringe. But, there is another option, an insulin pump. An insulin pump delivers rapid acting insulin in two ways. First, the pump is programmed to give you insulin every hour throughout the hour referred to basal insulin. Basal, think “base,” is the insulin your body needs even in the absence of food, it is also referred to as background insulin. This basal rate replaces the long acting injection that you take. Second, is bolus, this is the insulin you take for food or to correct a high blood sugar. If you get basal and bolus confused, think “bowl”, as in you eat out of a bowl, to help you remember bolus is for food. Once you are on a pump, all insulin is delivered through the pump and shots are no longer necessary. Components There are a few things necessary to make a pump work. When a pump is shipped to someone: they will also need to send infusion sets, reservoirs, and possibly batteries, depending on your pump. Let’s talk about each component. Infusion Sets An infusion set is the part that is actually inserted into the body and has tubing that conn Continue reading >>

Insulin Pumps

Insulin Pumps

Not Just for Type 1 An estimated 350,000 people in the United States use insulin pumps today, and about 30,000 of those are believed to have Type 2 diabetes. Surprised? Type 2 diabetes is a progressive disease that causes many people who have it to eventually need to use insulin to control their blood glucose levels. Although many people still think insulin pumps are only for treatment of Type 1 diabetes, they can also be useful for some people with Type 2 diabetes. According to Charles H. Raine III, MD, a diabetologist in Orangeburg, South Carolina, who himself has Type 2 diabetes and uses an insulin pump, the criteria for a good pump candidate are the same, no matter what type of diabetes a person has. In general, a good pump candidate has uncontrolled blood glucose, but also has a desire to try for better control of his diabetes, is willing to measure and document food intake and blood glucose levels, and is physically, emotionally, and cognitively able to manage a pump (or has a caregiver who is). Another important characteristic is a willingness to keep appointments with members of his diabetes care team. Insulin pumps are cell-phone-size devices used to deliver preprogrammed and user-adjusted doses of insulin. Depending on the brand and model, they hold between 180 and 315 units of insulin. Most people use rapid-acting insulin — options include insulin lispro (brand name Humalog), insulin aspart (NovoLog), and insulin glulisine (Apidra) — in their pumps, with a few using Regular. Instead of using an intermediate- or long-acting insulin as a background — or basal — insulin, a user simulates the pancreas’s steady release of insulin by programming the pump to automatically give small amounts of the rapid-acting or Regular insulin around the clock, based on Continue reading >>

Insulin Pump Therapy For Type 2 Diabetes

Insulin Pump Therapy For Type 2 Diabetes

The Simple Truth About Insulin Pump Therapy You have type 2 diabetes, but diabetes shouldn’t rule your life. You want to manage your sugar levels well, but with shots, you must deal with frequent challenges to keep your sugar levels under control. You wish there was an easier way to manage insulin dosing without compromising your health. You’re not alone. MiniMed insulin pump therapy helps you achieve better control by providing convenient insulin delivery that’s easy for you to manage. Only MiniMed insulin pump therapy is clinically proven to reduce A1C better than multiple daily shots for people with type 2 diabetes.4 Studies have shown that A1C reduction can significantly reduce the occurrence of long-term complications.5, 6 With MiniMed insulin pump therapy, you can worry less about your risk for long-term complications, such as: You are a candidate for MiniMed insulin pump therapy if: You are taking three or more insulin injections per day. You may be taking additional medications for your diabetes management, beyond just insulin. Your healthcare provider informed you that your A1C is elevated and your diabetes is not well controlled. You find it challenging to follow your prescribed insulin regimen for diabetes management. What is a pump and how does it work? The MiniMed insulin pump is an external device about the size of a cell phone that you can easily carry on a belt, place inside a pocket or wear under your clothes. The pump contains insulin and delivers it in a continuous and precise flow through a thin, flexible tube called an infusion set. The end of this tube sits comfortably under the skin and is replaced every two to three days. Basal rate You can program your insulin pump to continuously deliver tiny and precise amounts of insulin 24 hours a day. Continue reading >>

How Pumping Works

How Pumping Works

An insulin pump is a device about the size of a cell phone that contains a cartridge of rapid-acting insulin. A pump has a screen and buttons for programming the pump’s internal computer, and a precise motor that pushes the insulin from the cartridge into your body through a thin plastic tube called an infusion set. How is insulin delivered? Like your pancreas, an insulin pump releases small amounts of rapid-acting insulin to keep blood glucose levels steady between meals and during sleep. This is called the basal rate. Basal insulin takes the place of long-acting insulin. Then, at meal or snack time, you can tell the pump to deliver the amount of insulin needed to match the grams of carbohydrate in the food that is eaten, just like a healthy pancreas. This is called a bolus. A bolus can also be given to correct a high blood glucose. How is an insulin pump connected to my body? Every 2-3 days, a thin plastic tube called a cannula is inserted just underneath the skin using an infusion set. The infusion set is typically an all-in-one set that uses a thin introducer needle to insert the soft, thin cannula, which is then removed once the cannula is under the skin. A tube connects the infusion set to the pump using a Luer connector, a standard locking mechanism that securely attaches the tube to the pump.. Your healthcare professional will help you determine the best insulin infusion site for you. Typical infusion sites include the abdomen, hips, buttocks, upper back arm, and thighs. How is an insulin pump worn? Most pumps are so small and discreet, no one has to know you're wearing one unless you want them to. Plus, there are so many accessories available, you have many options to choose from. And for pumps that share information and communicate wirelessly using a meter-r Continue reading >>

Insulin Pumps

Insulin Pumps

Insulin pumps are an increasingly common treatment for type 1 diabetes. They can improve glucose control in people with type 1 diabetes but do not suit everyone. An insulin pump delivers insulin every few minutes in tiny amounts, 24 hours a day. It is usually about the size of a deck of cards, but can be much smaller. The insulin flows through a cannula which sits in the subcutaneous tissue (where you inject) and is changed by the pump user every few days. Basal (background) insulin is programmed to meet the pump user’s needs. The bolus insulin is delivered at the touch of a button to cover food or bring down a high blood glucose level. Only rapid-acting insulin is needed and provides all your insulin requirements. Insulin pumps reduce the need for multiple injections and give the user the ability to make smaller, more accurate adjustments to insulin delivery. Note: insulin pumps do not measure blood glucose levels, but some pumps can read the signal from a separate glucose sensor. What sort of insulin pumps are there? There are a number of different types of insulin pump and accessories. They vary in aspects such as weight; units of adjustment; whether they have tubing or not and battery life. A ‘tethered’ pump uses a fine tube to connect the pump to the cannula; the pump is worn in a pocket or clipped to a belt. A patch pump or micro pump has no tubing or a very short tube, and the pump is usually stuck on to the skin. The following suppliers currently offer pumps in the UK: Animas Advanced Therapeutics Cellnovo Medtronic Roche OmniPod A good document for comparison can be downloaded here. Type 1 Technology guide We have produced a family-friendly guide to type 1 diabetes technology, which highlights recommendations from NICE on treatments and technology for chi Continue reading >>

Insulin Analogs

Insulin Analogs

Insulin analogs mimic the body’s natural pattern of insulin release. Once absorbed, they act on cells like human insulin, but are absorbed from fatty tissue more predictably. An analog refers to something that is “analogous” or similar to something else. Therefore, “insulin” analogs are analogs that have been designed to mimic the body’s natural pattern of insulin release. These synthetic-made insulins are called analogs of human insulin. However, they have minor structural or amino acid changes that give them special desirable characteristics when injected under the skin. Once absorbed, they act on cells like human insulin, but are absorbed from fatty tissue more predictably. In this section, you will find information about: Rapid-acting injected insulin analog The fastest working insulins are referred to as rapid-acting insulin. They include: These insulin analogs enter the bloodstream within minutes, so it is important to inject them within 5 to 10 minutes of eating. They have a peak action period of 60-120 minutes, and fade completely after about four hours. Higher doses may last slightly longer, but will last no more than five or six hours. Rapid acting insulin analogs are ideal for bolus insulin replacement. They are given at mealtimes and for high blood sugar correction. Rapid-acting insulins are used in insulin pumps, also known as continuous subcutaneous insulin infusion (CSII) devices. When delivered through a CSII pump, the rapid-acting insulins provide the basal insulin replacement, as well as the mealtime and high blood sugar correction insulin replacement. The insulins that work for the longest period of time are referred to as long-acting insulin. They provide relatively constant insulin levels that plateau for many hours after injection. Some Continue reading >>

Type 1 Insulin Pump Therapy

Type 1 Insulin Pump Therapy

Insulin pump therapy can improve your blood sugar control. Insulin pumps more closely mimic what your body does naturally, so you can enjoy a more flexible lifestyle. Insulin pump therapy is an increasingly popular method of insulin replacement therapy. Because the insulin delivery from insulin pumps can more closely mimic what your body does naturally, you can improve your blood sugar control. With that control comes a more flexible lifestyle. Remember, though, that the pumps still require a lot of input from users. If you are wondering whether you should use a pump or are already on a pump, this section explains: Advanced programming features: How to get the most out of the pump and use all the options Ketones and insulin pumps: Why to watch for ketones and what to do if you have them Self-assessment Quiz Self assessment quizzes are available for topics covered in this website. To find out how much you have learned about Insulin Pumps, take our self assessment quiz when you have completed this section. The quiz is multiple choice. Please choose the single best answer to each question. At the end of the quiz, your score will display. If your score is over 70% correct, you are doing very well. If your score is less than 70%, you can return to this section and review the information. Continue reading >>

Insulin Pump For Diabetes

Insulin Pump For Diabetes

How does an insulin pump work? The typical insulin pump is attached to a thin plastic tube (an infusion set) that has a soft cannula (or plastic needle) at the end through which insulin passes. This cannula is inserted under the skin, usually on the abdomen. The cannula is changed every two days. The tubing can be disconnected from the pump while showering or swimming. The pump is used for continuous insulin delivery, 24 hours a day. The amount of insulin is programmed and is administered at a constant rate (basal rate). Often, the amount of insulin needed over the course of 24 hours varies depending on factors like exercise, activity level, and sleep. The insulin pump allows the user to program many different basal rates to allow for variation in lifestyle. In addition, the user can program the pump to deliver a bolus (large dose of insulin) during meals to cover the excess demands of carbohydrate ingestion. How common is an insulin pump? Hundreds of thousands of people with diabetes worldwide are using an insulin pump. Although insulin pumps were first used by people with type 1 diabetes, people with type 2 diabetes sometime use them as well. Many children successfully use insulin pumps. Insulin pumps allow for tight blood sugar control and lifestyle flexibility while minimizing the effects of low blood sugar (hypoglycemia). Newer models of the pump have been developed that do not require a tubing, in fact - the insulin delivery device is placed directly on the skin and any adjustments needed for insulin delivery are made through a PDA like device that must be kept within a 6 foot range of the insulin delivery device, and can be worn in a pocket, kept in a purse, or on a tabletop when working. Probably the most exciting innovation in pump technology is the ability to Continue reading >>

Long-acting Insulin Analogs Versus Insulin Pump Therapy For The Treatment Of Type 1 And Type 2 Diabetes

Long-acting Insulin Analogs Versus Insulin Pump Therapy For The Treatment Of Type 1 And Type 2 Diabetes

Insulin pump therapy (continuous subcutaneous insulin infusion [CSII]) is now an established form of intensive insulin treatment. It is pertinent to ask, however, if multiple daily injection (MDI) regimens based on new long-acting insulin analogs such as glargine and detemir have now replaced the need for CSII. In type 1 diabetes, CSII reduces the frequency of severe hypoglycemia compared with isophane-based MDIs, but the rate of severe hypoglycemia is usually similar on glargine- or detemir-based MDIs compared with isophane-based MDIs. CSII reduces A1C and glycemic variability compared with isophane-based MDIs; but glargine and detemir do not improve A1C or variability in many patients, particularly those who are prone to hypoglycemia. Head-to-head comparisons of CSII with MDI based on glargine indicate lower A1C, fructosamine, or glucose levels on CSII. It can be concluded that long-acting insulin analogs have not yet replaced the need for insulin pump therapy in type 1 diabetes, and CSII is the best current therapeutic option for some type 1 diabetic subjects. In type 2 diabetes, CSII and MDI produce similar glycemic control, although there is little study of MDI based on long-acting analogs compared with pumps. It is possible that CSII will be beneficial in selected patient groups with type 2 diabetes, but this requires further study. For many decades, it has been accepted that poor glycemic control in insulin injection–treated diabetes is mainly due to the inadequacies of insulin pharmacology (1,2). Regular (short-acting) insulin is absorbed too slowly from the subcutaneous site to control postprandial hyperglycemia, and the delayed absorption then results in late hypoglycemia. Both of these problems have now been much improved by the introduction of more quickly Continue reading >>

Novolog® (insulin Aspart Injection) 100 U/ml Indications And Usage

Novolog® (insulin Aspart Injection) 100 U/ml Indications And Usage

NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. NovoLog® (insulin aspart injection) 100 U/mL is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. Hypoglycemia is the most common adverse effect of insulin therapy. The timing of hypoglycemia may reflect the time-action profile of the insulin formulation. Glucose monitoring is re Continue reading >>

Insulin Pump

Insulin Pump

An insulin pump is a medical device used for the administration of insulin in the treatment of diabetes mellitus, also known as continuous subcutaneous insulin infusion therapy. The device configuration may vary depending on design. A traditional pump includes: the pump (including controls, processing module, and batteries) a disposable reservoir for insulin (inside the pump) a disposable infusion set, including a cannula for subcutaneous insertion (under the skin) and a tubing system to interface the insulin reservoir to the cannula. Other configurations are possible. For instance, more recent models may include disposable or semi-disposable designs for the pumping mechanism and may eliminate tubing from the infusion set. An insulin pump is an alternative to multiple daily injections of insulin by insulin syringes or an insulin pen and allows for intensive insulin therapy when used in conjunction with blood glucose monitoring and carb counting. Medical uses[edit] Advantages[edit] Users report better quality of life (QOL) compared to using other devices for administering insulin. The improvement in QOL is reported in type 1 and insulin-requiring type 2 diabetes subjects on pumps.[1] The use of rapid-acting insulin for basal needs offers relative freedom from a structured meal and exercise regime previously needed to control blood sugar with slow-acting insulin.[citation needed] Programmable basal rates allow for scheduled insulin deliveries of varying amounts at different times of the day. This is especially useful in controlling events such as the dawn phenomenon resulting in less low blood sugar during the night.[2] Many users feel that bolusing insulin from a pump is more convenient and discreet than injection.[2][3] Insulin pumps make it possible to deliver more pre Continue reading >>

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