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What Causes Lack Of Insulin In The Body?

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Facts About Diabetes And Insulin

Diabetes is a very common disease, which, if not treated, can be very dangerous. There are two types of diabetes. They were once called juvenile-onset diabetes and adult diabetes. However, today we know that all ages can get both types so they are simply called type 1 and type 2 diabetes. Type 1, which occurs in approximately 10 percent of all cases, is an autoimmune disease in which the immune system, by mistake, attacks its own insulin-producing cells so that insufficient amounts of insulin are produced - or no insulin at all. Type 1 affects predominantly young people and usually makes its debut before the age of 30, and most frequently between the ages of 10 and 14. Type 2, which makes up the remaining 90 percent of diabetes cases, commonly affects patients during the second half of their lives. The cells of the body no longer react to insulin as they should. This is called insulin resistance. In the early 1920s, Frederick Banting, John Macleod, George Best and Bertram Collip isolated the hormone insulin and purified it so that it could be administered to humans. This was a major breakthrough in the treatment of diabetes type 1. Insulin Insulin is a hormone. Hormones are chemica Continue reading >>

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Popular Questions

  1. molson1959

    lack of insulin or insulin resistance

    Greetings members,
    As a newbie T2, i have lots of questions as i am sure a lot of you had.
    Can someone tell me in general terms how treatment differs with the two distinct diabetes problems mentioned above.
    I have looked through the forums but did not find what i was looking for, if this has been covered previously, accept my opologizes and perhaps direct me to the correct thread
    Thanks in advance
    mike

  2. jwags

    Welcome Mike to DD. Lack of insulin or insulin insufficiency can be tested by a C Peptide test. Insulin resistance can also be tested with a C Peptide. If you have a high level of insulin and high fasting numbers you probably are insulin resistant. A very low number may indicate lack of insulin. Once your beta cells are damaged they usually don't regenerate and you will probably need injected insulin.

  3. Lynnw

    From what I've read, a lot of doctors don't make the distinction between IR and insulin insufficiency. To my doctor, high blood sugar is the issue...WHY it's high is irrelevant. He started going down his list of medications, starting with Metformin. If it didn't work, he'd shrug and try the next drug on the list. I had to beg him to do tests (except lipids...he was crazy for lipid tests, even though mine were good every time). I want answers, so I wasn't happy with that. Seems to me you'd want to know WHY it's high to determine the best treatment.

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