Diet For Hyperinsulinism
Based in Springfield, Mo., Jillian Ball, registered and licensed dietitian, has been writing nutrition-based content since 2004. Ball is a nutrition consultant and diabetes educator, and is certified in childhood and adolescent weight management. She holds a bachelor's degree in dietetics with cum laude honors from Missouri State University. Insulin and syringe.Photo Credit: Creatas Images/Creatas/Getty Images Hyperinsulinism occurs when the body produces too much insulin. According to Genetics Home Reference, this can happen as a result of genetics, called familial hyperinsulinism, or it can occur in response to insulin resistance, which causes the pancreas to overproduce insulin in an effort to maintain normal blood sugar levels. Insulin is a hormone that is released in response to glucose, or sugar, in the blood stream, making diet a major part of treatment. Doctors may not identify hyperinsulinism.Photo Credit: Monkey Business Images/Monkey Business/Getty Images The identification, or diagnosis, of hyperinsulinism often goes undetected by you or your doctor. Explained by the January 2013 "Gene Reveiw," hyperinsulinism does not usually present itself with signs or symptoms until low blood sugar occurs, also known as hypoglycemia. Even then, signs of hypoglycemia are somewhat generic resulting in fatigue, weakness, dizziness or irritability, which can point to a number of conditions. In infants, hyperinsulinism symptoms include poor feeding and seizures. Diet is important to keep healthy.Photo Credit: olgakr/iStock/Getty Images When combating abnormalities in glucose -- sugar -- or insulin regulation in the body, diet intake is always a concern and should be closely monitored. Sugar, especially refined sugars such as white or brown sugar, honey, jellies and syrups, w Continue reading >>
Causes Of Insulin Resistance And Hyperinsulinism
Home Conditions Insulin Resistance Causes of Insulin Resistance and Hyperinsulinism Causes of Insulin Resistance and Hyperinsulinism The Causes of Insulin Resistance and Hyperinsulinism The main reason for hyperinsulinism or excessive release of insulin is insulin resistance . Most of the time people get insulin resistance as a result of eating too much and being overweight. Even if you are overweight, theyre ways to increase insulin sensitivity . Usually, if people lose weight their insulin resistance will go down. One should realize that insulin resistance is a broad term and that you could be insulin sensitive in one way and resistant in another. Fat, muscle and the liver store glucose . You could be insulin sensitive in your muscles and resistant in your fat cells, in which case youll be muscular and lean. This isnt always optimally healthy. For example, if you have elevated levels of the inflammatory cytokine TNF-alpha it will cause insulin resistance in fat cells but not muscle cells. This isnt a good situation even though aesthetically youll look good. Sometimesthin people can also have insulin resistance. PCOS is a relatively common disorder among women, affecting up to 10% of women 12-45. Thin women with PCOS also have insulin resistance. There is also research that suggests that there is a male version of PCOS experienced by a certain percentage of men. PCOS and its associated IR is much easier to detect in women because of overt androgenic signs like facial hair growth, alopecia (balding) and fertility issues, but males can have a similar kind of issue and wouldnt be noticeable because men all healthy men have facial hair, etc However, the symptoms can manifest itself as premature balding. In thin people, IR can in part be caused by an inefficient conversion Continue reading >>
How Hyperinsulinemia Affects Your Health
Hyperinsulinemia is a medical condition where the pancreas produces excess insulin, which results in high insulin levels in your blood stream. This disorder can result from a variety of medical conditions. Hyperinsulinemia (also called insulin resistance) is linked to obesity as well as many other health problems. Although people who have hyperinsulinemia may exhibit few or no symptoms, there can be some indicators that suggest testing is needed. However, many signs also mimic symptoms of other health issues. If you experience any of the symptoms below, you need to schedule a consultation and diagnostic testing with your medical practitioner. Weight gain (or resistant to weight loss techniques) Visual problems such as blurred vision or double vision Like other health conditions, you can reduce the risks of hyperinsulinemia by making good lifestyle choices. Following a healthy diet that is rich in vegetables and fruits is an excellent start. Its also important to avoid starchy foods (breads, pasta, etc.) that cause high insulin. Daily exercise is also important. Contact us for nutritional support, guidance and or group classes in creating a healthier lifestyle. People with hyperinsulinemia are at risk for high triglycerides, low HDL and type II diabetes. In addition, you have an increased risk for kidney and heart disease. Its often associated with other metabolic disorders such as glucose intolerance and dyslipidemia. This close association between metabolic disorders and hyperinsulinemia suggest that they are linked. The sooner your symptoms are diagnosed with a treatment plan, the sooner you can reduce your health risks and damage. Check out our hyperinsulin article to learn more. Then, take control of your health. Contact us to discuss your symptoms or request your Continue reading >>
What medical conditions are associated with insulin resistance? While the metabolic syndrome links insulin resistance with abdominal obesity, elevated cholesterol, and high blood pressure; several other medical other conditions are specifically associated with insulin resistance. Insulin resistance may contribute to the following conditions: Type 2 Diabetes: Overt diabetes may be the first sign insulin resistance is present. Insulin resistance can be noted long before type 2 diabetes develops. Individuals reluctant or unable to see a health-care professional often seek medical attention when they have already developed type 2 diabetes and insulin resistance. Fatty liver: Fatty liver is strongly associated with insulin resistance. Accumulation of fat in the liver is a manifestation of the disordered control of lipids that occurs with insulin resistance. Fatty liver associated with insulin resistance may be mild or severe. Newer evidence suggests fatty liver may even lead to cirrhosis of the liver and, possibly, liver cancer. Arteriosclerosis: Arteriosclerosis (also known as atherosclerosis) is a process of progressive thickening and hardening of the walls of medium-sized and large arteries. Arteriosclerosis is responsible for: Other risk factors for arteriosclerosis include: High levels of "bad" (LDL) cholesterol Diabetes mellitus from any cause Family history of arteriosclerosis Skin Lesions: Skin lesions include increased skin tags and a condition called acanthosis nigerians (AN). Acanthosis nigricans is a darkening and thickening of the skin, especially in folds such as the neck, under the arms, and in the groin. This condition is directly related to the insulin resistance, though the exact mechanism is not clear. Acanthosis nigricans is a cosmetic condition strongly Continue reading >>
Hyperinsulinemia: Is It Diabetes?
Is hyperinsulinemia a form of diabetes? Answers from M. Regina Castro, M.D. Hyperinsulinemia (hi-pur-in-suh-lih-NEE-me-uh) means the amount of insulin in your blood is higher than what's considered normal. Alone, it isn't diabetes. But hyperinsulinemia is often associated with type 2 diabetes. Insulin is a hormone that's normally produced by your pancreas, which helps regulate blood sugar. Hyperinsulinemia is a sign of an underlying problem. Hyperinsulinemia is most often caused by insulin resistance — a condition in which your body doesn't respond well to the effects of insulin. Your pancreas tries to compensate by making more insulin. Insulin resistance may eventually lead to the development of type 2 diabetes. This happens when your pancreas is no longer able to compensate by secreting the large amounts of insulin required to keep the blood sugar normal. Rarely, hyperinsulinemia is caused by: A rare tumor of the insulin-producing cells of the pancreas (insulinoma) Excessive numbers or growth of insulin-producing cells in the pancreas (nesidioblastosis) Hyperinsulinemia usually causes no signs or symptoms, except in people with insulinomas in whom hyperinsulemia can cause low blood sugar (hypoglycemia). Treatment of hyperinsulinemia is directed at the underlying problem. Continue reading >>
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Determination Of Insulin For The Diagnosis Of Hyperinsulinemic Hypoglycemia
Determination of Insulin for the Diagnosis of Hyperinsulinemic Hypoglycemia The publisher's final edited version of this article is available at Best Pract Res Clin Endocrinol Metab See other articles in PMC that cite the published article. Hyperinsulinemic hypoglycemia is the most common cause of persistent hypoglycemia in children and adults. The diagnosis of hyperinsulinemic hypoglycemia relies on the evaluation of the biochemical profile at the time of hypoglycemia, however, contrary to common perception, plasma insulin is not always elevated. Thus, the diagnosis must often be based on the examination of other physiologic manifestations of excessive insulin secretion, such as suppression of glycogenolysis, lipolysis and ketogenesis, which can be inferred by the finding of a glycemic response to glucagon, and the suppression of plasma free fatty acids and beta-hydroxybutyrate concentrations during hypoglycemia. Keywords: hypoglycemia, insulinoma, hyperinsulinism, beta cells, pancreas Hyperinsulinemic hypoglycemia is the most frequent cause of persistent hypoglycemia in children and adults. In adults, hyperinsulinemic hypoglycemia is most commonly an acquired problem due to an insulin-secreting tumor; while in children, with only rare exceptions, it represents a congenital disorder ( 1 ). The development of a radioimmunoassay for insulin by Yalow and Berson in 1960 ( 2 ) made it possible to demonstrate the role of endogenous insulin in hypoglycemic disorders. However, as discussed below, simply measuring plasma insulin concentrations is often not enough to establish the diagnosis of hyperinsulinemic hypoglycemia. A literature search of PubMed ( ) was performed for studies published up to April 2013. Keywords used included insulin, C-peptide, proinsulin, insulin assay Continue reading >>
Hyperinsulinemia: Symptoms, Treatments, And Diet
The typical cause of hyperinsulinemia is insulin resistance . Insulin resistance is what happens when your body doesnt respond correctly to insulin. This incorrect response causes your body to need the pancreas to produce more insulin. As your pancreas makes more insulin, your body continues to resist and respond incorrectly to the higher levels of insulin. Your pancreas will continually need to make more to compensate. Eventually, your pancreas wont be able to keep up with the amount of insulin your body needs to keep your blood sugar at a healthy level. Insulin resistance can eventually lead to type 2 diabetes . Less common causes of this condition are insulinoma and nesidioblastosis. Insulinoma is a rare tumor of the pancreas cells that produce insulin. Nesidioblastosis is when the pancreas produces too many cells that make insulin. Hyperinsulinemia may also develop after having gastric bypass surgery. The theory is that the cells have become too large and active for the body, but the body has changed significantly after the bypass. Doctors arent fully sure why this happens. Hyperinsulinemia is usually diagnosed through a blood test taken when youre fasting. It may also be diagnosed when your doctor is checking for other conditions like diabetes. Treatment for hyperinsulinemia begins by treating whatever is causing it. This is particularly true if your condition is caused by insulinoma or nesidioblastosis. Your treatment may also include a combination of medication, lifestyle changes, and possibly surgery. These lifestyle changes include diet and exercise. The medications used to treat this condition are the same or similar to the medications used to treat diabetes. However, medication should be used only if diet and exercise arent enough to control the condition. S Continue reading >>
Hyperinsulinemia is a condition where the blood insulin level is higher than what is considered normal in people without diabetes. Although hyperinsulinemia is not diabetes, the condition is often associated with type 2 diabetes. People with hyperinsulinemia have difficulty maintaining a normal blood sugar level, which means the pancreas has to produce increasing amounts of insulin in order to control it. The primary cause of hyperinsulinemia is insulin resistance, which occurs when the insulin level remains high enough over a long period for the body to become less sensitive to the hormone. This means that the body’s usual response to a given amount of insulin is decreased, which results in the pancreas secreting higher levels of insulin in order for the hormone to exert its usual effects. The pancreas produces increasing levels of insulin until eventually it can no longer produce enough to meet the body’s needs. This leads to a rise in the blood sugar level and insulin resistance is therefore a risk factor for the development of diabetes. In rare cases, hyperinsulinemia may be caused by the presence of a tumor in the insulin-producing cells (islets of Langerhans) of the pancreas. This tumor is referred to as an insulinoma. Another rare cause is a condition called nesidioblastosis, a genetic disorder where abnormal islets of Langerhans produce an excess of insulin. Insulin resistance may occur in response to the body’s endogenous insulin or exogenous insulin given via injection. Insulin resistance is closely associated with inflammation and is thought to be caused by cytokine release disrupting the usual action of insulin. The chronic inflammation seen in obesity can therefore increases the risk of type 2 diabetes. Symptoms of insulin resistance One of the first Continue reading >>
General Discussion Congenital hyperinsulinism (HI) is the most frequent cause of severe, persistent hypoglycemia in newborn babies, infants, and children. In most countries it occurs in approximately 1/25,000 to 1/50,000 births. About 60% of babies with HI are diagnosed during the first month of life. An additional 30% will be diagnosed later in the first year and the remainder after that. With early treatment and aggressive prevention of hypoglycemia, brain damage can be prevented. However, brain damage can occur in children with HI if the condition is not recognized or if treatment is ineffective in the prevention of hypoglycemia. Insulin is the most important hormone for controlling the concentration of glucose in the blood. As food is eaten, blood glucose rises and the pancreas secretes insulin to keep blood glucose in the normal range. Insulin acts by driving glucose into the cells of the body. This action of insulin maintains blood glucose levels and stores glucose as glycogen in the liver. Once feeding is completed and glucose levels fall, insulin secretion is turned off, allowing the stores of glucose in glycogen to be released into the bloodstream to keep blood glucose normal. In addition, with the switching off of insulin secretion, protein and fat stores become accessible and can be used instead of glucose as sources of fuel. In this manner, whether one eats or is fasting blood glucose levels remain in the normal range and the body has access to energy at all times. This close regulation of blood glucose and insulin secretion does not occur normally in people who have HI. The beta cells in the pancreas, which are responsible for insulin secretion, are blind to the blood glucose level and secrete insulin regardless of the blood glucose concentration. As a resu Continue reading >>
Hyperinsulinemia And Insulin Resistance: World's Biggest Killers?
When we think about the world’s biggest killer, different things come to mind. Or possibly heart disease, cancer, or maybe even dementia? Well, those three chronic diseases are all good bets. But what if they are just the result of something else, and they all have a common cause? In that case, that common cause could be the world’s biggest killer – and it goes by the name of hyperinsulinemia. This article takes a look at the rapidly growing problem of hyperinsulinemia and insulin resistance, and how they affect our health . Insulin resistance is a term to describe when our body develops a resistance to the effects of the hormone insulin ( 1 ). As a result, we experience increasing blood sugar levels and higher levels of circulating insulin ( 2 , 3 ). Hyperinsulinemia refers to the situation where we have a constant elevation of insulin levels ( 4 ). The literal definition is simply an excess amount of insulin in the blood. Insulin resistance is the usual cause of hyperinsulinemia, and the resulting high insulin levels can be very damaging to our body ( 5 ). There is a strong connection between hyperinsulinemia and type 2 diabetes, but they are not the same thing. Type 2 diabetes occurs when the pancreas fails to produce enough insulin to maintain normal blood sugar levels ( 6 ). However, hyperinsulinemia refers to when the body is producing too much insulin to keep high blood sugar levels in check ( 7 ). Without adequate intervention, chronic hyperinsulinemia can lead to type 2 diabetes ( 8 ). But it must be remembered: hyperinsulinemia is associated with metabolic syndrome, and it’s harmful independently of diabetes. Key Point: Insulin resistance leads to hyperinsulinemia – excess amounts of circulating insulin in the body. As shown above, insulin resist Continue reading >>
Hyperinsulinemia: A Cause Of Obesity?
1Obesity Research Center, Department of Medicine, Boston University School of Medicine, 650 Albany St, Boston, MA 02118 USA 2Division of Endocrinology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA USA 1Obesity Research Center, Department of Medicine, Boston University School of Medicine, 650 Albany St, Boston, MA 02118 USA 1Obesity Research Center, Department of Medicine, Boston University School of Medicine, 650 Albany St, Boston, MA 02118 USA 2Division of Endocrinology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA USA Karel A. Erion, Email: [email protected] . Author information Copyright and License information Disclaimer Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. This perspective is motivated by the need to question dogma that does not work: that the problem is insulin resistance (IR). We highlight the need to investigate potential environmental obesogens and toxins. The prequel to severe metabolic disease includes three interacting components that are abnormal: (a) IR, (b) elevated lipids and (c) elevated basal insulin (HI). HI is more common than IR and is a significant independent predictor of diabetes. We hypothesize that (1) the initiating defect is HI that increases nutrient consumption and hyperlipidemia (HL); (2) the cause of HI may include food additives, environmental obesogens or toxins that have entered our f Continue reading >>
Hyperinsulinemia, The Danger Of Too Much Insulin
Hyperinsulinemia is not another word for type 2 diabetes or even for borderline diabetes. It literally means there is too much insulin in your blood. If you have high blood sugar, that is called hyperglycemia. Too little sugar is hypoglycemia. Both can be found in a diabetic. Your pancreas, or more precisely the beta cells inside it, make the two hormones that keep glucose at a safe and steady level in your blood. Hormones make them part of your endocrine system. Endocrine glands release the hormones that affect every organ and cell, and they always come in pairs so they can balance, or turn on and off effects like your bone growth, mood and digestion. An endocrinologist is the kind of doctor who specializes in endocrine systems. That's why type 2 diabetic doctors are endocrinologists. They study the disease and its symptoms, and they have learned how to treat those symptoms. They can identify hyperinsulinemia, and they know what it does. Elevated insulin in the blood causes an increased inflammatory effect in every organ of the body. That doesn't sound terrible until you look at problems caused by inflammation. Here are just a few: Crohn's disease, rheumatoid arthritis, chronic fatigue syndrome, diabetes, Alzheimer's and Parkinson's. In hyperinsulinemia your pancreas is putting out larger amounts of insulin than your cells can use. The excess insulin builds up in your blood. Sometimes this is because of insulin resistance in the cells. Doctors know insulin resistance is connected to the metabolic syndrome. For diabetics this compounds the problems caused by high blood sugar. Elevated sugar in your blood damages blood vessels and spreads candidal infections through your bloodstream. Hyperglycemic symptoms are not as obvious as those for hypoglycemia, which is why it is Continue reading >>
Hyperinsulinemia is the state of having increased fasting insulin level in the blood that is beyond normal level. Although it is often associated with type 2 diabetes, hyperinsulinemia does not necessarily mean that one is diabetic. Hyperinsulinemia is a condition when the body produces too much insulin than what it usually needs. Insulin is a hormone produced by the pancreas, an endocrine organ located in the upper portion of the abdomen. Its function is to regulate the entry of sugar (glucose) into the cells, which use it to produce energy, and to store excess sugar in the liver for later use. The body detects an increase in sugar in the blood when food is ingested, which signals the pancreas to produce insulin. An increase in insulin allows sugar to enter the cells to be converted to energy. The reduction of sugar levels in the blood triggers the pancreas to stop producing insulin, until more food is ingested. Insulin therefore regulates blood sugar levels, thus preventing a condition known as hyperglycemia (high blood sugar levels), which is often associated with type 2 diabetes. However, some people tend to produce too much insulin compared to other people, even when they are in a fasting state, signalling hyperinsulinemia. This condition is strongly linked to an underlying condition, which could lead to other health problems. The most common cause of hyperinsulinemia is insulin resistance, a condition where the cells are resistant to insulin effects, and are thereby unable to utilize glucose. To compensate, the pancreas compensates by producing more insulin. Insulin resistance is a condition that covers a wide clinical spectrum, including obesity, glucose intolerance (prediabetes), diabetes, and metabolic syndrome. These disorders, in turn are linked with various Continue reading >>
Hyperinsulinemia Symptoms, Diagnosis, Treatments And Causes - Rightdiagnosis.com
Hyperinsulemia means having too much insulin in the bloodstream.Hyperinsulemia is a common condition in Type 2 diabetes with underlying cause of insulin resistence .It is a somewhat paradoxical situation because you can be diabetic and still have too much insulin in your body.Ordinarily, too much insulin would lead to a low ( hypo ), but with insulin resistence,the body cannot use the insulin that it has,and for various reasons the pancreas actually produces more insulin leadingto an excess of insulin in the bloodstream. The fact that hyperinsulemia occurs is the basis of some low-carbo diets,such as the Dr Atkins diet.The theory is that diabetics cannot lose weight because there is alwaystoo much insulin around that processes every single ounce of carbothat you eat, adding weight.Hence, for a diabetic, it might appear that a low-carbo dietwould work, not a low fat diet.On the other hand, insulin resistence should preventthat excess insulin from processing all the carbo,so perhaps the whole premise is unjustified.As with all diets, the issue is unclear. ... more There are no real symptoms in a diabetic . In a non-diabetic, hyperinsulemia would lead rapidly to a dangerous hypo ,but in a Type 2 diabetic the insulin resistence nullifies the hyperinsulemia. ... more symptoms The correct approach for treatment of hyperinsulinemia is unclear.Hyperinsulemia does not typically require special treatment for a diabetic,unless it is extreme.Moderate hyperinsulemia is common in Type 2 diabetics ,but is neutralized by the insulin resistence .Hence, many Type 2 diabetics do not require special treatment for hyperinsulemia,though they need to treat the ... more treatments In-Depth Reports: Diagnosis and Misdiagnosis Diabetes diagnosis and misdiagnosis (In-Depth Report): Detailed repo Continue reading >>
Tweet Hyperinsulinemia is often associated with type 2 diabetes, but it isn’t diabetes as such. Hyperinsulinemia means that the amount of insulin in the blood is higher than considered normal amongst non-diabetics. When a person has hyperinsulinemia they have a problem controlling blood sugar, meaning that the pancreas has to secrete larger amounts of insulin to keep blood sugar at a normal level. How is hyperinsulinemia caused? Insulin resistance is the primary cause of hyperinsulinemia, with the pancreas compensating by producing more insulin. Insulin resistance of this type can lead to the development of type 2 diabetes, which occurs when the pancreas cannot secrete the insulin required to maintain normal blood glucose levels. In more rare cases, hyperinsulinemia may be caused by a tumour of the insulin-producing cells of the pancreas (insulinoma). It may also be caused by excessive numbers of insulin-producing cells in the pancreas (nesidioblastosis). What are the risks of having hyperinsulinemia? There are a number of risks involved in having hyperinsulinemia which include: Higher triglyceride levels High uric acid Hardening of the arteries (artherosclerosis) Weight gain Hypertension Type 2 diabetes The sooner hyperinsulinemia is diagnosed, which may be in the form of pre-diabetes or type 2 diabetes, the sooner the risks or extent of the above can be reduced. What are the symptoms of hyperinsulinemia? Although hyperinsulinemia often has little clear indicator, hyperinsulinemia symptoms may include: Weight gain Cravings for sugar Intense hunger Feeling frequently hungry Difficulty concentrating Feeling anxious or panicky Lacking focus or motivation Fatigue How is hyperinsulinemia treated? Medical treatment, in the form of diabetes medication, may help to relieve t Continue reading >>