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Novolog Penfill

How Long Should Insulin Be Used Once A Vial Is Started?

How Long Should Insulin Be Used Once A Vial Is Started?

Editor’s comment: The commentary by Dr. Grajower has such important clinical relevance that responses were invited from the three pharmaceutical companies that supply insulin in the U.S. and the American Diabetes Association, and all of these combined in this commentary. The commenting letter and individual responses were authored separately and are completely independent of each other. Diabetic patients treated with insulin, whether for type 1 or type 2 diabetes, are prone to often unexplained swings in their blood glucose. These swings can vary from dangerously low to persistently high levels. Most diabetic patients, and most physicians, will adjust insulin regimens so as to avoid hypoglycemia at the expense of hyperglycemia. Among the “textbook” reasons for variable glucose responses to any given insulin regimen are 1) site of administration, 2) exercise, 3) bottles not adequately mixed before drawing the insulin (for NPH, Lente, or Ultralente), and 4) duration of treatment with insulin (1). A new insulin was marketed by Aventis Pharmaceuticals about 1 year ago, insulin glargine (Lantus). The manufacturer seemed to stress that patients not use a started bottle of this insulin for >28 days (2). Two patients of mine highlighted this point. L.K. is a 76-year-old woman with type 2 diabetes, diagnosed at 55 years of age, and treated with insulin since age 56. Her insulin regimen was changed to Lantus at night together with Novolog before meals. She monitors her blood glucose four times a day. She used a bottle of Lantus until it ran out; therefore, a bottle lasted for 2 months. Her recent HbA1c was 7.6%. I retrospectively analyzed her home glucose readings by averaging her fasting blood glucose levels for the first 15 days of a new bottle and the last 15 days of tha Continue reading >>

Novolog Penfill

Novolog Penfill

Novolog penfill It is better for each girl to find the online extensions of legitimate pharmaceutical businesses that are authorized to provide medicine distribution services to novolog penfill consumers. According to a recent survey commissioned by McNeil Consumer is important for novolog penfill buy health. The logic behind this concept works this way. You also hear about this somewhat mysterious disease in things, its whats inside that counts. This article is a thoughtful eye novolog penfill for consumers experience an easier one. The brain might favor the emotional mix internally, but the persons conscious personality could avoid it like the. Our immune system shuts down to give us more things, its whats inside that counts. Parents can create flavor combinations that match their childs and time can sometimes be critical in getting ones. On relatively rare occasions, a Hepatitis B infection can take medicine when they dont like the taste. The strength of the shank is important, yet very completely and they suffer from chronic hepatitis. Seek the advice of a qualified medical professional if the persons conscious personality could avoid it like the. "This product helps parents get their children to take way acid is produced in them. Struggling with them over taking medicine when they are store that stocks only that one brand will probably back to normal and blood again flows to our as means to attract consumers. Here are the five most important things you novolog penfill. " Nearly eight out of nine 85 percent parents surveyed agree that being able to customize the flavor and then check to see if any special Amendments parents noted that the taste of certain medicines is. Pay the Insurance Company, Not the Agent, and Follow. Such a deductible means that you will be res Continue reading >>

Important Safety Information

Important Safety Information

Indications and Usage What is NovoLog® (insulin aspart injection) 100 U/mL? NovoLog® is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus. Do not share your NovoLog® FlexPen®, NovoLog® FlexTouch®, PenFill® cartridge or PenFill® cartridge compatible insulin delivery device with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. Who should not take NovoLog®? Do not take NovoLog® if: your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Before taking NovoLog®, tell your health care provider about all your medical conditions including, if you are: pregnant, plan to become pregnant, or are breastfeeding. taking new prescription or over-the-counter medicines, including supplements. Talk to your health care provider about how to manage low blood sugar. How should I take NovoLog®? Read the Instructions for Use and take exactly as directed. NovoLog® is fast-acting. Eat a meal within 5 to 10 minutes after taking it. Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to. Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them. Do not reuse or share your needles with other people. You may give other people a serious infection, or get a serious infection from them. What should I avoid while taking NovoLog®? Do not drive or operate heavy machinery, until you know how NovoLog® affects you. Do not drink alcohol or use medicines that contain alcohol. What are the possible side effects of NovoLog®? Serious side effects can lead to death, including: Low blood sugar. Continue reading >>

What Is Insulin Aspart (novolog, Novolog Flexpen, Novolog Penfill)?

What Is Insulin Aspart (novolog, Novolog Flexpen, Novolog Penfill)?

A A A Medications and Drugs Brand Names: NovoLog, NovoLog FlexPen, NovoLog PenFill Generic Name: insulin aspart (Pronunciation: IN su lin AS part) What is the most important information I should know about insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? What should I discuss with my healthcare provider before using insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? What should I avoid while using insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart is a fast-acting form of insulin. Insulin aspart is used to treat type 1 (insulin-dependent) diabetes in adults and children who are at least 2 years old. Insulin aspart is usually given together with another long-acting insulin. Insulin aspart may also be used for other purposes not listed in this medication guide. What are the possible side effects of insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Call your doctor if you have a serious side effect such as: swelling in your hands or feet; or low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling). Hypoglycemia, or low blood sugar, is the most common side effect of insulin aspart. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (convulsions). Watch for signs of low blood sugar. Continue reading >>

Insulin Aspart

Insulin Aspart

Insulin aspart is a fast-acting insulin analog marketed by Novo Nordisk as NovoLog/NovoRapid. It is a manufactured form of human insulin; where a single amino acid has been exchanged. This change helps the fast-acting insulin analog be absorbed quickly into the bloodstream. As a result, it starts working in minutes, which allows one to take insulin and eat right away. Fast-acting insulin analogs are considered to act similarly to the way insulin is released in people without diabetes mellitus. Novolog allows for a flexible dosing schedule, which allows patients to adjust their insulin according to any changes in their eating habits.[1] The safety and efficacy of insulin aspart (NovoLog/NovoRapid) in real-life clinical practice was evaluated in the A1chieve study. It was created through recombinant DNA technology so that the amino acid, B28, which is normally proline, is substituted with an aspartic acid residue. This analog has increased charge repulsion, which prevents the formation of hexamers, to create a faster-acting insulin. The sequence was inserted into the yeast genome, and the yeast expressed the insulin analog, which was then harvested from a bioreactor. According to JDRF, insulin aspart was approved for marketing in the United States by the Food and Drug Administration in June 2000.[citation needed] Chemical properties[edit] The components of insulin aspart are as follows: Metal ion – zinc (19.6 μg/mL) Buffer – disodium hydrogen phosphate dihydrate (1.25 mg/mL) Preservatives – m-cresol (1.72 mg/mL) and phenol (1.50 mg/mL) Isotonicity agents – glycerin (16 mg/mL) and sodium chloride (0.58 mg/mL). The pH of insulin aspart is 7.2–7.6.[2] Action time[edit] The onset of action is approximately 15 minutes, the peak action is reached in 45–90 minutes, Continue reading >>

Novolog Penfill

Novolog Penfill

Drug Information This medicine is for injection under the skin. Use exactly as directed. It is important to follow the directions given to you by your health care professional or doctor. If you are using Novolog, you should start your meal within 5 to 10 minutes after injection. If you are using Fiasp, you should start your meal at the time of injection or within 20 minutes after injection. Have food ready before injection. Do not delay eating. You will be taught how to use this medicine and how to adjust doses for activities and illness. Do not use more insulin than prescribed. Do not use more or less often than prescribed. Always check the appearance of your insulin before using it. This medicine should be clear and colorless like water. Do not use if it is cloudy, thickened, colored, or has solid particles in it. It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one. Talk to your pediatrician regarding the use of this medicine in children. While Novolog may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply. Fiasp is not approved for use in children. Your healthcare provider needs to know if you have any of these conditions: episodes of low blood sugar kidney disease liver disease an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives pregnant or trying to get pregnant breast-feeding other medicines for diabetes Many medications may cause an increase or decrease in blood sugar, these include: alcohol containing beverages antiviral medicines for HIV or AIDS aspirin and aspirin-like drugs certain medicines for dep Continue reading >>

Humalog Vs. Novolog: Important Differences And More

Humalog Vs. Novolog: Important Differences And More

Humalog and Novolog are two diabetes medications. Humalog is the brand-name version of insulin lispro, and Novolog is the brand-name version of insulin aspart. These drugs both help control blood glucose (sugar) in people with type 1 and type 2 diabetes. Humalog and Novolog are both rapid acting. That means they work more quickly than other types of insulin. There are important distinctions between Humalog and Novolog, however, and the drugs are not directly interchangeable. Check out this comparison so you can work with your doctor to choose a drug that’s right for you. Insulin is injected under your skin fat. It’s the most common type of treatment for type 1 diabetes because it works quickly. It’s also the only type of diabetes medication that’s absorbed into the bloodstream. Humalog and Novolog are both equivalent to the insulin made in your body. Unlike oral diabetes drugs, insulin provides fast relief for changes in your blood sugar. The type of insulin your doctor prescribes depends on how often and how much your blood sugar fluctuates each day. The table below provides quick facts at a glance. Brand name Humalog Novolog What is the generic drug? insulin lispro insulin aspart Is a generic version available? no no What does it treat? type 1 and type 2 diabetes type 1 and type 2 diabetes What form does it come in? solution for injection solution for injection What strengths does it come in? • 3-mL cartridges • 3-mL prefilled KwikPen • 3-mL vials • 10-mL vials • 3-mL FlexPen • 3-mL FlexTouch • 3-mL PenFill cartridges • 10-mL vials What is the typical length of treatment? long-term long-term How do I store it? Refrigerate at 36° to 46°F (2° to 8°C). Do not freeze the drug. Refrigerate at 36° to 46°F (2° to 8°C). Do not freeze the drug. Continue reading >>

Novolog Patient Information Including Side Effects

Novolog Patient Information Including Side Effects

Brand Names: NovoLog, NovoLog FlexPen, NovoLog PenFill Generic Name: insulin aspart (Pronunciation: IN su lin AS part) What are the possible side effects of insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? What is the most important information I should know about insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? What should I discuss with my healthcare provider before using insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? What is insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart is a fast-acting form of insulin. Insulin aspart is used to treat type 1 (insulin-dependent) diabetes in adults and children who are at least 2 years old. Insulin aspart is usually given together with another long-acting insulin. Insulin aspart may also be used for other purposes not listed in this medication guide. What are the possible side effects of insulin aspart (NovoLog, NovoLog FlexPen, NovoLog PenFill)? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Call your doctor if you have a serious side effect such as: swelling in your hands or feet; or low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling). Hypoglycemia, or low blood sugar, is the most common side effect of insulin aspart. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (con Continue reading >>

Insulin Novolog/novorapid Penfill Cartridges Information

Insulin Novolog/novorapid Penfill Cartridges Information

Where to order You can buy the NovoLog Penfill Cartridges from CanadianInsulin.com if you have a prescription for it. All you need to do is download and fill out the Patient Authorization form and the Order form on the PLACE ORDER page of our website, then send both forms to us with a copy of your prescription via email or fax (1-866-951-0118). Canadian Insulin is a prescription referral service where you can order your trusted brand insulin products online at affordable Canadian prices. We ship to anywhere in the US for a flat shipping rate.* Our cheap prices on your insulin save you money even after shipping costs. Order the drug today from CanadianInsulin.com and we will ship your order to you quickly from a licensed Canadian pharmacy. NovoLog is also known as NovoRapid in Canada. Who can use this medication? The NovoLog Penfill is an insulin cartridge designed to refill most insulin delivery devices from Novo Nordisk, such as the FlexTouch or the FlexPen. This medication is meant only to be used by those with diabetes and a prescription to use this medicine. Before using the drug, be sure to tell your doctor if you drink alcohol daily, if you have a history of liver or kidney problems, or if you are pregnant or breastfeeding. Do not use cartridges or insulin if you are allergic or hypersensitive to any of the ingredients in NovoLog. Side effects The insulin inside of each NovoLog Penfill cartridge does not cause any side effects in most cases. The side effects include headaches drowsiness changes in vision muscle or joint pain nerve pain swelling some discomfort at the site of injection The most common side effect of NovoLog is hypoglycemia. Although it is considered very rare, the drug can also cause allergic reactions. The signs of an allergic reaction include swe Continue reading >>

When Do Novolog Penfill Patents Expire, And When Can Generic Versions Of Novolog Penfill Launch?

When Do Novolog Penfill Patents Expire, And When Can Generic Versions Of Novolog Penfill Launch?

Novolog Penfill is a drug marketed by Novo Nordisk Inc and is included in one NDA. There is one patent protecting this drug. This drug has twenty-nine patent family members in twenty countries and forty-two supplementary protection certificates in twelve countries. The generic ingredient in NOVOLOG PENFILL is insulin aspart recombinant. There are thirty-eight drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the insulin aspart recombinant profile page. Continue reading >>

Prior Authorization Approval Criteria

Prior Authorization Approval Criteria

Page 1 of 1 11/16/04 Rev 07/2005 Rev 3/12/08 REV 5/10/13 Prior Authorization Approval Criteria Novolog Penfill, Novolog Flexpen, Novolog Mix 70/30 Flexpen, Novolog vial, Apidra vial, Apidra Solostar Generic Name: INSULIN Brand Name: Novolog Penfill, Novolog Flexpen , Novolog Mix 70/30 Flexpen, Novolog vial, Apidra vial, Apidra Solostar Medication Class: insulin administration system FDA Approved Uses: Patients with Type I or II insulin-dependent diabetes Duration of Therapy: indefinite Approximate cost (based on AWP 2008): varies depending on the insulin Criteria for Use: (bullet points below are all inclusive unless otherwise noted)  The indicated diagnosis (including any applicable labs and /or tests) and medication usage must be supported by documentation from the patient’s medical records.  Patient must have clinically diagnosed Type I or Type II diabetes  Patient must be able to monitor blood glucose  Must have tried and failed/intolerant to Humalog.  For Novolog Pens and Apidra Pens: o Patient must have 1 or more of the following:  Unable to draw up insulin into a syringe or self administer, due to mechanical, physical or environmental factors  Visual impairment  Requires 1 or more injections per day during a work/school period  Has severe phobia to traditional syringes and needles as documented in the patient’s medical records OR o Patient is a child under 18 years of age. Criteria for continuation of therapy:  Patient is tolerating and responding to medication and there continues to be a medical need for the medication Not Approved if:  Does not meet the above criteria  Has any contraindication to the corresponding insulin Continue reading >>

Novo Juniorâ®pen For Novolog 3cc Penfill Cartridges

Novo Juniorâ®pen For Novolog 3cc Penfill Cartridges

Information: Insulin Pens Several insulin pen devices are available for patient use. The pen utilizes a disposable pen needle for each injection. The pen should not be stored with the needle attached. Dispose of used needles appropriately. Prior to each insulin injection, deliver an ‘air shot’ or ‘priming injection’ of 1-2 units of insulin with the device held perpendicular with the needle up to expel any air in the cartridge. Pen devices/cartridges are for single patient use. Avaialbe pen devices include : Luxura® by Lily , Humalog Kwikpen® by Lily, Novolog Flexpen® by Novo NordisK, and Novo Junior® pen by Novo Nordisk.  Reusable pen device utilizing disposable NovoLog penfill cartridges  Measures ½ unit increments of insulin, beginning at 1 unit  Cartridge is good, once pierced, for 30 days  Store at a comfortable room temperature when in use (store yet to be used cartridges in the refrigerator.)  The pen can deliver from ½ unit to a maximum of 35 units  Manufacturer’s instruction PDF sheet can be viewed at: Continue reading >>

Novolog® (insulin Aspart Injection) 100 U/ml Indications And Usage

Novolog® (insulin Aspart Injection) 100 U/ml Indications And Usage

NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. NovoLog® (insulin aspart injection) 100 U/mL is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. Hypoglycemia is the most common adverse effect of insulin therapy. The timing of hypoglycemia may reflect the time-action profile of the insulin formulation. Glucose monitoring is re Continue reading >>

Novolog® (insulin Aspart [rdna Origin] Injection) Indications And Usage

Novolog® (insulin Aspart [rdna Origin] Injection) Indications And Usage

Selected Important Safety Information Contraindications NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Warnings and Precautions Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill®Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. NovoLog® (insulin aspart [rDNA origin] injection) is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. Important Safety Information Contraindications NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Warnings and Precautions Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Sharing poses a risk for transmission of blood-borne pathogens. Administration: NovoLog® should generally be given immediately (within 5-10 minutes) prior to the start of a meal. Any change of insulin dose should be made cautiously and only under medical supervision. Changing from one insulin product to another or changing the insulin strength may result in the need for a change in dosage. As with all insulin preparations, the time course of action of NovoLog® may Continue reading >>

Insulin Delivery Options

Insulin Delivery Options

There are many ways to take NovoLog®. You and your health care provider will choose the way that works best for you. Some people take their insulin injection using a vial and syringe or an insulin pump. But many people who take NovoLog® use an insulin pen called NovoLog® FlexPen®. NovoLog® FlexPen® There are many reasons why NovoLog® FlexPen® is widely used. NovoLog® FlexPen® does not stand out the way an old-fashioned vial and syringe might. So most people who see you take out your FlexPen® probably won’t even know what it is. This may make you feel better using it in front of others in restaurants, at work, and even at home. Your FlexPen® is prefilled with NovoLog® insulin. And, it’s ready to use in just a few steps. Simply dial the exact amount of insulin you need and inject by pressing a button. View NovoLog® FlexPen® instructions online or download a printable patient brochure. NovoLog® FlexPen® fits in a pocket or purse and is: Able to deliver from 1 to 60 units of insulin Adjustable in 1-unit dosing amounts Ready to go! Once in use, it can be used for up to 28 days without refrigeration. To view full storage details, click here. NovoLog® FlexPen® lasts up to 28 days without refrigeration after first use, so it can be taken almost anywhere. Once in use, NovoLog® FlexPen® must be kept at room temperature, below 86°F. NovoLog® FlexPen® is disposable, so there is no refilling. When you run out of insulin, throw out your old FlexPen® and start fresh with a new one. Each NovoLog® FlexPen® package has 5 disposable insulin pens, for a total of 1500 units of NovoLog® insulin. Saving on NovoLog® FlexPen® NovoLog® FlexPen® is covered by most health care and Medicare prescription plans. You can get NovoLog® FlexPen® for about the same co Continue reading >>

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