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Novolog 70/30 Vs Novolog

What Is Premixed Insulin?

What Is Premixed Insulin?

Insulin that comes in pre-mixed formulations combines insulins that have different onsets (how quickly they begin to work) and durations (how long the effects last) to best manage the blood glucose levels of the individual. Rapid-acting insulins work well for the increase in blood glucose that occurs right after meals, while longer-acting insulins help maintain blood glucose levels between meals and overnight. Many patients like pre-mixed insulins as they help reduce the number of injections needed per day, however they are not convenient for intensive insulin regimens. A person with diabetes may need to change their insulin regimen if they experience changes in their physical activity, weight gain or loss, increased stress, illness, or a change in diet. Changes like these should be discussed with a healthcare professional. Always check with your healthcare professional about any potential drug interactions before starting treatment and report any side effects you experience. Some of the long-acting insulins available in the US include: Humalog Mix 50/50 is a mix of 50% of a rapid-acting insulin (insulin lispro) and an intermediate-acting insulin (insulin lispro protamine suspension) used to treat adults with diabetes for the control of blood sugar. The rapid-acting insulin goes to work quickly in about 15 to 30 minutes, stimulating the cells to absorb glucose for their energy needs, while the intermediate acting insulin reaches its peak effect 2 to 4 hours after injection and continues working for up to 22 hours.* In addition to stimulating the absorption of glucose, insulin promotes the storage of glucose in the form of glycogen in the liver, stops the liver from producing more glucose, and promotes the conversion of excess glucose into fat. Humalog Mix 50/50 is avail Continue reading >>

Novolin 70/30 And Novolog Mix 70/30

Novolin 70/30 And Novolog Mix 70/30

Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. I'm curious to know if there is a difference between the two other than naming. I ask because I currently take Novolin 70/30 right now, but need the convenience of a pen needle. Novolin 70/30 doesnt have a pen but Novolog 70/30 does. They both seem to be made by Novo Nordisk but the website wasnt giving me the answer I'm looking for. I would (of course) ask my doctor, but that requires an appointment which is at this point 3 weeks away From a quick look around it appears that Novolin 70/30 contains regular insulin as the bolus component, while Novolog mix contains rapid (Novolog) insulin as the bolus component. Yep, they are different insulins and the bolus portion of the Novolog mix is intended to work a lot faster. You might also be able to get the Novolin mix in pen cartridges for refillable pens, if you end up deciding you want to stay with it. LocationSomewhare in the South Pacific??? I would think that they are the same. Just different names. Look at the active constitutent. Novolin is the older "slower" acting insulin. Novolog is the current "fasting" acting insulin. As such, they are not the same. I used to use the novolog flex pen as the fast acting before the novolin 70/30. So the novolog 70/30 flex pen is the same as the novolog flex pen? I understood the novolin 70/30 was a mix of slow and fast. Is this not what the novolog 70/30 is? I think im confusing myself lol If you use Novolog as the fast acting insulin. Chance are you also have a slow one (basel) like Lantus or Levemir. Novolog 70/30 is a mix of fast and slow. So that does a close job of Novolog+Levemir. I say close is bec Continue reading >>

Insulin Aspart

Insulin Aspart

Insulin aspart is a fast-acting insulin analog marketed by Novo Nordisk as NovoLog/NovoRapid. It is a manufactured form of human insulin; where a single amino acid has been exchanged. This change helps the fast-acting insulin analog be absorbed quickly into the bloodstream. As a result, it starts working in minutes, which allows one to take insulin and eat right away. Fast-acting insulin analogs are considered to act similarly to the way insulin is released in people without diabetes mellitus. Novolog allows for a flexible dosing schedule, which allows patients to adjust their insulin according to any changes in their eating habits.[1] The safety and efficacy of insulin aspart (NovoLog/NovoRapid) in real-life clinical practice was evaluated in the A1chieve study. It was created through recombinant DNA technology so that the amino acid, B28, which is normally proline, is substituted with an aspartic acid residue. This analog has increased charge repulsion, which prevents the formation of hexamers, to create a faster-acting insulin. The sequence was inserted into the yeast genome, and the yeast expressed the insulin analog, which was then harvested from a bioreactor. According to JDRF, insulin aspart was approved for marketing in the United States by the Food and Drug Administration in June 2000.[citation needed] Chemical properties[edit] The components of insulin aspart are as follows: Metal ion – zinc (19.6 μg/mL) Buffer – disodium hydrogen phosphate dihydrate (1.25 mg/mL) Preservatives – m-cresol (1.72 mg/mL) and phenol (1.50 mg/mL) Isotonicity agents – glycerin (16 mg/mL) and sodium chloride (0.58 mg/mL). The pH of insulin aspart is 7.2–7.6.[2] Action time[edit] The onset of action is approximately 15 minutes, the peak action is reached in 45–90 minutes, Continue reading >>

Novolog Mix 70/30, Novolog Mix 70/30 Flexpen, Novolog Mix 70/30 Penfill (insulin Aspart And Insulin Aspart Protamine) Drug Side Effects, Interactions, And Medication Information On Emedicinehealth.

Novolog Mix 70/30, Novolog Mix 70/30 Flexpen, Novolog Mix 70/30 Penfill (insulin Aspart And Insulin Aspart Protamine) Drug Side Effects, Interactions, And Medication Information On Emedicinehealth.

What is insulin aspart and insulin aspart protamine (NovoLog Mix 70/30, NovoLog Mix 70/30 FlexPen, Novolog Mix 70/30 PenFill)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart and insulin aspart protamine is a faster-acting form of insulin than regular human insulin. Insulin aspart and insulin aspart protamine is used to treat type 1 (insulin-dependent) diabetes in adults. Insulin aspart and insulin aspart protamine may also be used for purposes not listed in this medication guide. What are the possible side effects of insulin aspart and insulin aspart protamine (NovoLog Mix 70/30, NovoLog Mix 70/30 FlexPen, Novolog Mix 70/30 PenFill)? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Hypoglycemia, or low blood sugar, is the most common side effect of insulin. Symptoms include headache , hunger, weakness, sweating, tremors , irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting , or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar. Call your doctor at once if you have a serious side effect such as: low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling). Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin aspart and insulin aspart protamine. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-10 Continue reading >>

Study Demonstrates Long-term Efficacy And Safety Of Novolog® Mix 70/30 In Type 2 Diabetes As Compared To Biphasic Human Insulin 30

Study Demonstrates Long-term Efficacy And Safety Of Novolog® Mix 70/30 In Type 2 Diabetes As Compared To Biphasic Human Insulin 30

1 Preliminary data from the INITIATE study was initially presented at the 64th annual meeting of the American Diabetes Association (ADA) held in Orlando, Florida in June 2004. According to a two-year head-to-head study published today in the European Journal of Internal Medicine, patients with type 2 diabetes showed reduced incidences of major hypoglycemia when using Novolog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]) versus biphasic human insulin 30 (Novolin® 70/30, 70% NPH, human insulin isophane suspension and 30% regular, human insulin injection [rDNA origin]) (0% vs. 10%, p=0.04)) with comparable efficacy.1 "It appears that NovoLog® Mix 70/30 is a useful pharmacological tool that can help to redress the balance between hypoglycemia and hyperglycemia in the daily challenge to manage blood glucose levels in type 2 diabetes," concluded Bernhard Böhm,M.D.,Ph.D. Department of Internal Medicine, University of Ulm, Germany and lead investigator of the study. Symptoms associated with hypoglycemia, a condition that develops when blood glucose levels are critically low due to inappropriately matched levels of injected insulin, include disorientation, delirium, loss of consciousness, and in severe cases, coma and death. "The use of insulin in type 2 diabetes patients remains a barrier for many physicians and many patients. The ability to achieve comparable levels of glucose control with a premixed analog insulin and premixed human insulin but with a lower risk of major hypoglycemia as shown in European Journal of Internal Medicine report is significant," said Alan Moses, M.D., associate vice president of medical affairs, Novo Nordisk Inc. The two-year study, performed at 30 centers in Germany, was comprised of a thr Continue reading >>

Novolog Mix 70-30

Novolog Mix 70-30

NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart) Injection, [rDNA origin]) Suspension for Subcutaneous Injection DESCRIPTION NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]) is a human insulin analog suspension containing 70% insulin aspart protamine crystals and 30% soluble insulin aspart. NovoLog Mix 70/30 is a blood glucoselowering agent with an earlier onset and an intermediate duration of action. Insulin aspart is homologous with regular human insulin with the exception of a single substitution of the amino acid proline by aspartic acid in position B28, and is produced by recombinant DNA technology utilizing Saccharomyces cerevisiae (baker's part (NovoLog) has the empirical formula C256H381N65O79S6 and a molecular weight of 5825.8 Da. Figure 1: Structural formula of insulin aspart NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) is a uniform, white, sterile suspension that contains insulin aspart 100 Units/mL. Inactive ingredients for the 10 mL vial are mannitol 36.4 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 μg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.58 mg/mL, and protamine sulfate 0.32 mg/mL. Inactive ingredients for the NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) FlexPen are glycerol 16.0 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 μg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.877 mg/mL, and protamine sulfate 0.32 mg/mL. NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) has a pH of 7.20 - 7.44. Hydrochloric acid or sodium hydroxide may Continue reading >>

What Is Novolog (insulin Aspart)?

What Is Novolog (insulin Aspart)?

Before you receive DARZALEX®, tell your healthcare provider about all of your medical conditions, including if you: have a history of breathing problems have had shingles (herpes zoster) are pregnant or plan to become pregnant. DARZALEX® may harm your unborn baby. Females who are able to become pregnant should use an effective method of birth control during treatment and for at least 3 months after your final dose of DARZALEX®. Talk to your healthcare provider about birth control methods that you can use during this time. are breastfeeding or plan to breastfeed. It is not known if DARZALEX® passes into your breast milk. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DARZALEX® may be given alone or together with other medicines used to treat multiple myeloma. Your healthcare provider will decide the time between doses as well as how many treatments you will receive. Your healthcare provider will give you medicines before each dose of DARZALEX® and on the first day after each dose of DARZALEX® to help reduce the risk of infusion reactions. If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment. Infusion reactions. Infusion reactions are common with DARZALEX® and can be severe. Your healthcare provider may temporarily stop your infusion or completely stop treatment with DARZALEX® if you have infusion reactions. Tell your healthcare provider right away if you get any of the following symptoms: shortness of breath or trouble breathing dizziness or lightheadedness (hypotension) cough wheezing throat tightness runny or stuffy nose headache itching nausea vomiting chills fever Changes in blood tests. DARZALEX Continue reading >>

Product Important Safety Information

Product Important Safety Information

Selected Important Safety Information WARNING: RISK OF THYROID C-CELL TUMORS Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. It is unknown whether Victoza® causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of liraglutide-induced rodent thyroid C-cell tumors has not been determined. Victoza® is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk for MTC with the use of Victoza® and inform them of symptoms of thyroid tumors (eg, a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Victoza®. Selected Important Safety Information Tresiba® is contraindicated during episodes of hypoglycemia and in patients with hypersensitivity to Tresiba® or one of its excipients Levemir® is contraindicated in patients with hypersensitivity to Levemir® or any of its excipients NovoLog® and NovoLog® Mix 70/30 are contraindicated during episodes of hypoglycemia and in patients hypersensitive to insulin aspart or any of the excipients Warnings and Precautions Never Share a Tresiba® FlexTouch®; Levemir® FlexTouch®, NovoLog® FlexPen, NovoLog®FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device; or NovoLog®Mix 70/30 FlexPen® Between Patients, even if the needle is changed. Patients using vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens Hypoglyc Continue reading >>

The Difference Between Novolin Vs Novolog

The Difference Between Novolin Vs Novolog

What is Novolin? Novolin is a man made insulin that is used to control high blood sugar in people with diabetes. Insulin is a naturally occurring hormone that is produced by the hormone to help glucose get absorbed by the body cells for energy. Without insulin, there will be a build up of glucose in the blood, which can lead to high blood sugar. If high blood sugar is left untreated, it can lead to severe health complications including nerve damage, kidney damage, blindness and loss of limbs. Novolin is usually a combination of insulin isophane and insulin regular, that uses proper diet and exercise to improve blood sugar levels in people with diabetes. Whereas insulin isophane is an intermediate acting insulin, insulin regular is a short acting insulin. When you take this combination of insulin it starts to work within 10 to 20 minutes after injecting it under your skin. The medication usually peaks after 2 hours and can last up to 24 hours. What is Novolog? Novolog refers to a fast acting insulin, which helps to control blood glucose levels in patients with type 2 diabetes. This insulin begins to work within 15 minutes after injection. Novolog usually peaks after one hour and the effects can last between 2 to 4 hours. Since Novolog is a very fast acting insulin, it is recommended you eat within 5 to 10 minutes after taking an injection. Similarities Both Novolin and Novolog refer to man made insulin that is taken by diabetic patients to help them control their blood sugar levels. Both medications are injectable insulins that are taken by injecting them subcutaneously. To avoid the risk of transferring infections from one person to another, you should not share an injection pen with anyone. Another similarity is that both medicines have a clear appearance. You should n Continue reading >>

What Is The Difference Between Novolog 70/30 And Regular Novolog Flexpen?

What Is The Difference Between Novolog 70/30 And Regular Novolog Flexpen?

Home Q & A Questions What is the difference... What is the difference between novolog 70/30 and regular novolog flexpen? novolog , novolog flexpen , diabetes, type 2 I've always used novolog 70/30 flexpen, last week I had my refill and was given regular novolog, I'm wondering if I'm getting the same benefit? My bs has been higher than usual and I'm worried. Continue reading >>

What Is Novolog 70/30?

What Is Novolog 70/30?

QUICK LINKS Insulin aspart protamine and insulin aspart is a combination of a fast-acting insulin and an intermediate-acting type of human insulin. Insulin is used by people with diabetes to help keep blood sugar levels under control. When you have diabetes mellitus, your body cannot make enough or does not use insulin properly. So, you must take additional insulin to regulate your blood sugar and keep your body healthy. This is very important as too much sugar in your blood can be harmful to your health. This medicine is available only with your doctor's prescription. Find big savings at pharmacies near you with GoodRx discount coupons Lowest GoodRx Price $526.00 View All Prices A nurse or other trained health professional may give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot under your skin. Always double-check both the concentration (strength) of your insulin and your dose. Concentration and dose are not the same. The dose is how many units of insulin you will use. The concentration tells how many units of insulin are in each milliliter (mL), such as 100 units/mL (U-100), but this does not mean you will use 100 units at a time. Each package of insulin aspart protamine and insulin aspart combination contains a patient information sheet. Read this sheet carefully before beginning your treatment and each time you refill the medicine for any new information, and make sure you understand: How to prepare the medicine. How to inject the medicine. How to use disposable insulin delivery device. How to dispose of syringes, needles, and injection devices. It is best to use a different place on the body for each injection (eg, under the skin of your abdomen or stomach, thigh, buttocks, or upper arm). If you have qu Continue reading >>

Humulin 70/30 Mix And Novolog 70/30 Mix

Humulin 70/30 Mix And Novolog 70/30 Mix

Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. Hi to all. Can anyone tell me is Humulin good as Novolog. They're both "good" for what they're intended...but since you posted this in the "complications" section, maybe you could expand a little on what you're actually trying to figure out. Important distinction to keep in mind: you'll see humalog referred to often. I'd say at least 95% of the time this is referring to the bolus only, non-mix version. Humulin also refers to a few different products, and is not always going to be the mix being referred to. But is not such a common insulin these days. As far as how they compare, I don't know of arguments saying one is not "as good" as the other. Here are some details for each, from this link. Continue reading >>

Mix 70/30 Flexpen

Mix 70/30 Flexpen

Please scroll down for Important Safety Information and Prescribing Information. NovoLog® Mix 70/30 is a premixed insulin that works in 2 different ways to lower your A1C. It controls blood sugar in between meals for up to 24 hours and treats blood sugar spikes when you eat. NovoLog® Mix 70/30 is available in 10 mL vials, and in FlexPen®, a discreet, prefilled, dial-a-dose insulin pen. For more information, visit www.novologmix70-30.com. Indications and Usage What is NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL? NovoLog® Mix 70/30 is a man-made insulin used to control high blood sugar in adults with diabetes mellitus. It is not known if NovoLog® Mix 70/30 is safe or effective in children. Important Safety Information Do not share your NovoLog®® with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. Who should not take NovoLog® Mix 70/30? Do not take NovoLog® Mix 70/30 if: your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Before taking NovoLog® Mix 70/30, tell your healthcare provider about all your medical conditions including, if you are: pregnant, planning to become pregnant, or are breastfeeding. taking new prescription or over-the-counter medicines, including supplements. Talk to your health care provider about how to manage low blood sugar. How should I take NovoLog® Mix 70/30? Read the Instructions for Use and take exactly as directed. NovoLog® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. If you have type 2 diabetes, inject within 15 minutes before or after starting your meal. Do not mix NovoLog® Mix 70/30 with othe Continue reading >>

Novolog Mix 70/30 Suspension For Injection Drug Information, Side Effects, Faqs

Novolog Mix 70/30 Suspension For Injection Drug Information, Side Effects, Faqs

They need to know if you have any of these conditions: -an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives This medicine is for injection under the skin. Use exactly as directed. It is important to follow the directions given to you by your health care professional or doctor. You should inject this medicine within 15 minutes of starting your meal. You will be taught how to use this medicine and how to adjust doses for activities and illness. Do not use more insulin than prescribed. Do not use more or less often than prescribed. Always check the appearance of your insulin before using it. This medicine should be white and cloudy. Do not use if it is not uniformly cloudy after mixing. To mix this medicine, roll the vial gently 10 times in your hands. Make sure to perform the mixing procedures before each injection. Do not mix this medicine with any other insulin or diluent. It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. It is important not to miss a dose. Your health care professional or doctor should discuss a plan for missed doses with you. If you do miss a dose, follow their plan. Do not take double doses. Visit your health care professional or doctor for regular checks on your progress. A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months. Learn how to check your blood sugar. Learn the symptoms of low and high bl Continue reading >>

Novolog Mix 70/30 Confusion

Novolog Mix 70/30 Confusion

When prescribing NovoLog® Mix 70/30 analog insulin, health care professionals may write an unclear prescription, or if using an EMR system, inadvertently select Novolin® 70/30 human insulin instead. Be on the lookout for these errors. Read on for a breakdown of the key differences between these 2 types of insulin. Before the new “insulin pens” came out, there were four types of insulin: rapid-acting, short-acting, intermediate-acting, and long-acting. When it comes to the pre-mixed insulins, like Novolog 70/30, there are fewer differences between the brands (for example, Novolog versus Novolin)…. Whether contained in a bottle or in a pen, the premixed insulins all contain a combination of both an intermediate-acting insulin and a short-acting insulin. The numbers on the bottle or pen refer to the percentage of each type of insulin contained in the mixture. That means both Novolin 70/30 and Novolog 70/30 contain a mixture that is 70% intermediate-acting insulin with 30% short-acting insulin. However, Novolin 70/30 takes slightly longer to begin working than Novolog 70/30, which has a rapid onset. Both Novolin 70/30 and Novolog 70/30 may last up to 24 hours in the system. Novolin® 70/30 is not available in a pen. Novolin is the brand name given to all human insulins made by Novo Nordisk. Under this brand are specific types of insulin such as regular, nph, and 70/30. Novolog insulin is a synthetic recombinant insulin that is very rapid acting. You may often get this question because novolog is more expensive than any of the novolins. However, they cannot be substituted for each other. Two euglycemic clamp studies assessed glucose utilization after dosing of healthy volunteers. NovoLog Mix 70/30 has an earlier onset of action than human premix 70/30 in studies of n Continue reading >>

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