Mix 70/30 Flexpen
Please scroll down for Important Safety Information and Prescribing Information. NovoLog® Mix 70/30 is a premixed insulin that works in 2 different ways to lower your A1C. It controls blood sugar in between meals for up to 24 hours and treats blood sugar spikes when you eat. NovoLog® Mix 70/30 is available in 10 mL vials, and in FlexPen®, a discreet, prefilled, dial-a-dose insulin pen. For more information, visit www.novologmix70-30.com. Indications and Usage What is NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL? NovoLog® Mix 70/30 is a man-made insulin used to control high blood sugar in adults with diabetes mellitus. It is not known if NovoLog® Mix 70/30 is safe or effective in children. Important Safety Information Do not share your NovoLog®® with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. Who should not take NovoLog® Mix 70/30? Do not take NovoLog® Mix 70/30 if: your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Before taking NovoLog® Mix 70/30, tell your healthcare provider about all your medical conditions including, if you are: pregnant, planning to become pregnant, or are breastfeeding. taking new prescription or over-the-counter medicines, including supplements. Talk to your health care provider about how to manage low blood sugar. How should I take NovoLog® Mix 70/30? Read the Instructions for Use and take exactly as directed. NovoLog® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. If you have type 2 diabetes, inject within 15 minutes before or after starting your meal. Do not mix NovoLog® Mix 70/30 with othe Continue reading >>
Selected Important Safety Information
NovoLog® Mix 70/30 is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® Mix 70/30 or one of its excipients. Never Share a NovoLog® Mix 70/30 FlexPen® Between Patients, even if the needle is changed. Patients using NovoLog® Mix 70/30 vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. Changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL Indications and Usage NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL is a mixture of insulin aspart protamine and insulin aspart indicated to improve glycemic control in patients with diabetes mellitus. NovoLog® Mix 70/30 is not recommended for the treatment of diabetic ketoacidosis. The proportions of rapid-acting and long-acting insulins are fixed and do not allow for basal versus prandial dose adjustments. NovoLog® Mix 70/30 is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® Mix 70/30 or one of its excipients. Never Share a NovoLog® Mix 70/30 FlexPen® Between Patients, even if the needle is changed. Patients using NovoLog® Mix 70/30 vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or Continue reading >>
Novolog Mix 70-30
NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart) Injection, [rDNA origin]) Suspension for Subcutaneous Injection DESCRIPTION NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]) is a human insulin analog suspension containing 70% insulin aspart protamine crystals and 30% soluble insulin aspart. NovoLog Mix 70/30 is a blood glucoselowering agent with an earlier onset and an intermediate duration of action. Insulin aspart is homologous with regular human insulin with the exception of a single substitution of the amino acid proline by aspartic acid in position B28, and is produced by recombinant DNA technology utilizing Saccharomyces cerevisiae (baker's part (NovoLog) has the empirical formula C256H381N65O79S6 and a molecular weight of 5825.8 Da. Figure 1: Structural formula of insulin aspart NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) is a uniform, white, sterile suspension that contains insulin aspart 100 Units/mL. Inactive ingredients for the 10 mL vial are mannitol 36.4 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 μg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.58 mg/mL, and protamine sulfate 0.32 mg/mL. Inactive ingredients for the NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) FlexPen are glycerol 16.0 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 μg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.877 mg/mL, and protamine sulfate 0.32 mg/mL. NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart rdna origin) has a pH of 7.20 - 7.44. Hydrochloric acid or sodium hydroxide may Continue reading >>
What Is Novolog 70/30?
QUICK LINKS Insulin aspart protamine and insulin aspart is a combination of a fast-acting insulin and an intermediate-acting type of human insulin. Insulin is used by people with diabetes to help keep blood sugar levels under control. When you have diabetes mellitus, your body cannot make enough or does not use insulin properly. So, you must take additional insulin to regulate your blood sugar and keep your body healthy. This is very important as too much sugar in your blood can be harmful to your health. This medicine is available only with your doctor's prescription. Find big savings at pharmacies near you with GoodRx discount coupons Lowest GoodRx Price $526.00 View All Prices A nurse or other trained health professional may give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot under your skin. Always double-check both the concentration (strength) of your insulin and your dose. Concentration and dose are not the same. The dose is how many units of insulin you will use. The concentration tells how many units of insulin are in each milliliter (mL), such as 100 units/mL (U-100), but this does not mean you will use 100 units at a time. Each package of insulin aspart protamine and insulin aspart combination contains a patient information sheet. Read this sheet carefully before beginning your treatment and each time you refill the medicine for any new information, and make sure you understand: How to prepare the medicine. How to inject the medicine. How to use disposable insulin delivery device. How to dispose of syringes, needles, and injection devices. It is best to use a different place on the body for each injection (eg, under the skin of your abdomen or stomach, thigh, buttocks, or upper arm). If you have qu Continue reading >>
Novolog Mix 70/30 Flexpen
Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin aspart is a fast-acting insulin. Insulin aspart protamine is an intermediate-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. NovoLog Mix 70/30 FlexPen is a combination medicine used to improve blood sugar control in adults with diabetes mellitus (type 1 or type 2). NovoLog Mix 70/30 FlexPen may also be used for purposes not listed in this medication guide. Never share an injection pen or syringe with another person, even if the needle has been changed. You should not use this medicine if you are allergic to insulin aspart, or if you are having an episode of hypoglycemia ( low blood sugar ). NovoLog Mix 70/30 FlexPen is not approved for use by anyone younger than 18 years old. To make sure this medicine is safe for you, tell your doctor if you have ever had: low levels of potassium in your blood ( hypokalemia ). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin ). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems. Follow your doctor's instructions about using insulin if you are pregnant or breast-feeding a baby. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Your dose needs may also be different while you are breast-feeding. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Insulin is injected under the skin. You will be shown how to use injections at home. Do not giv Continue reading >>
Novolog Mix 70/30 (insulin Aspart,insulin Aspart Protamine) Dosage, Indication, Interactions, Side Effects | Empr
Do not reuse or share pens between patients; or needles and syringes when using vials. Instruct patients on proper administration of insulin, check insulin label before each injection, and management of hypoglycemia. Increased risk of hypo- or hyperglycemia if changes in physical activity, meal patterns, renal or hepatic function, insulin regimen and if acute illness occurs: monitor glucose more frequently and may need to adjust dose. Monitor potassium levels in patients at risk for hypokalemia (eg, concomitant K+-lowering or K+-sensitive drugs). Discontinue if hypersensitivity reactions occur. Hyperglycemia and ketoacidosis due to insulin pump device malfunction: see full labeling. Renal or hepatic impairment. Pregnancy (Cat.B). Nursing mothers. Concomitant thiazolidinediones (TZDs) may cause fluid retention and heart failure; consider dose reduction or discontinue TZDs. Potentiated by oral antidiabetic agents, ACE inhibitors, ARBs, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analog, sulfonamide antibiotics. Antagonized by atypical antipsychotics, corticosteroids, isoniazid, niacin, danazol, diuretics, glucagon, thiazides, phenothiazines, sympathomimetics, somatropin, thyroid hormones, estrogens, progestogens, protease inhibitors. Variable effects with -blockers, clonidine, lithium salts, alcohol, pentamidine. Concomitant -blockers, clonidine, guanethidine, reserpine may blunt hypoglycemia. Do not mix with other insulins. Hypoglycemia, hypokalemia, local inj site reactions, lipodystrophy, rash, pruritus, edema, sodium retention, weight gain; hypersensitivity and allergic reactions. Continue reading >>
Novolog Mix 70-30
NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart (rdna origin)) is a form of insulin, a hormone that is produced in the body, used to treat type 1 (insulin-dependent) diabetes in adults. Common side effects of NovoLog Mix 70/30 include: redness, swelling or itching at the injection site. Side effects of NovoLog Mix 70/30 usually go away after a few days or weeks. Low blood sugar (hypoglycemia) is the most common side effect of NovoLog Mix 70/30 (insulin). Symptoms of low blood sugar include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure. NovoLog Mix 70/30 is typically dosed on a twice-daily basis (with each dose intended to cover 2 meals or a meal and a snack). Dosage is individualized. NovoLog Mix 70/30 may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. Many other medicines can increase or decrease the effects of insulin aspart and insulin aspart protamine on lowering your blood sugar. Tell your doctor all prescription and over-the-counter medications and supplements you use. Tell your doctor if you are pregnant before using NovoLog Mix 70/30. Consult your doctor to manage blood sugars before becoming pregnant. Your doctor may switch the type of insulin used during pregnancy. It is unknown if this drug passes into breast milk. Insulin needs may change while breastfeeding. Consult your doctor before breastfeeding. Our NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart (rdna origin)) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice Continue reading >>
Novolog® Mix 70/30 Storage
Home or Away, NovoLog® Mix 70/30 Goes With You NovoLog® lasts up to 14 days without refrigeration after first use, so it can be taken almost anywhere. Once in use, NovoLog® Mix 70/30 FlexPen® must be kept at room temperature below 86°F for up to 14 days. Here is a quick guide to NovoLog® Mix 70/30 storage: Not in use (unopened) Room temperature: below 86°F Not in use (unopened) Refrigerated In use (opened) Room temperature: below 86°F 10-mL vial 28 days Until expiration date 28 days (can be kept refrigerated or at room temperature) 3-mL NovoLog® Mix 70/30 FlexPen® 14 days Until expiration date 14 days (do not refrigerate) Do’s: Don’ts: Do store unused NovoLog® Mix 70/30 in a refrigerator between 36° to 46°F (2° and 8°C) Don't store NovoLog® Mix 70/30 in the freezer or directly adjacent to the refrigerator cooling element Don't freeze NovoLog® Mix 70/30 or use NovoLog® Mix 70/30 if it has been frozen Don't draw NovoLog® Mix 70/30 into a syringe and store for later use Do keep vials at temperatures below 86°F (30°C) for up to 28 days after initial use. Opened vials may be refrigerated Do use unpunctured vials until the expiration date printed on the label if they are stored in a refrigerator Do keep unused vials in the carton so they will stay clean and protected from light Don't expose vials to excessive heat or light Do keep NovoLog® Mix 70/30 FlexPen® at room temperatures below 86°F (30°C) for up to 14 days once it is punctured Don't store in use NovoLog® Mix 70/30 FlexPen® in the refrigerator Do keep NovoLog® Mix 70/30 FlexPen® away from direct heat and sunlight Don't expose NovoLog® Mix 70/30 FlexPen® to excessive heat or sunlight Do use unpunctured NovoLog® Mix 70/30 FlexPen® until the expiration date printed on the label if they Continue reading >>
Dailymed - Novolog Mix 70/30- Insulin Aspart Injection, Suspension
Table 3: Clinically Significant Drug Interactions with NOVOLOG MIX 70/30 Drugs that May Increase the Risk of Hypoglycemia Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics Dose adjustment and increased frequency of glucose monitoring may be required when NOVOLOG MIX 70/30 is co-administered with these drugs. Drugs that May Decrease the Blood Glucose Lowering Effect of NOVOLOG MIX 70/30 Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. Dose adjustment and increased frequency of glucose monitoring may be required when NOVOLOG MIX 70/30 is co-administered with these drugs. Drugs that May Increase or Decrease the Blood Glucose Lowering Effect ofNOVOLOG MIX 70/30 Alcohol, beta-blockers, clonidine, and lithium salts. Pentamidine may cause hypoglycemia, which may sometimes be followed by hyperglycemia. Dose adjustment and increased frequency of glucose monitoring may be required when NOVOLOG MIX 70/30 is co-administered with these drugs. Drugs that May Blunt Signs and Symptoms of Hypoglycemia Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use). Never Share a NOVOLOG MIX 70/30 FlexPen between Patients Advise patients that they must never share NOVOLOG MIX 70/30 FlexPen device with another person even if the needle is changed. Advise pati Continue reading >>
Novolog 70/30 Prices And Novolog 70/30 Coupons - Goodrx
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Novolog Mix 70/30, Novolog Mix 70/30 Flexpen, Novolog Mix 70/30 Penfill (insulin Aspart And Insulin Aspart Protamine) Drug Side Effects, Interactions, And Medication Information On Emedicinehealth.
What is insulin aspart and insulin aspart protamine (NovoLog Mix 70/30, NovoLog Mix 70/30 FlexPen, Novolog Mix 70/30 PenFill)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin aspart and insulin aspart protamine is a faster-acting form of insulin than regular human insulin. Insulin aspart and insulin aspart protamine is used to treat type 1 (insulin-dependent) diabetes in adults. Insulin aspart and insulin aspart protamine may also be used for purposes not listed in this medication guide. What are the possible side effects of insulin aspart and insulin aspart protamine (NovoLog Mix 70/30, NovoLog Mix 70/30 FlexPen, Novolog Mix 70/30 PenFill)? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Hypoglycemia, or low blood sugar, is the most common side effect of insulin. Symptoms include headache , hunger, weakness, sweating, tremors , irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting , or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar. Call your doctor at once if you have a serious side effect such as: low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling). Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin aspart and insulin aspart protamine. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-10 Continue reading >>
Novolog Mix 70-30 Flexpen Prescription Price Comparison | Compare Drug Prices | Scriptsave Wellrx
The entered address, city, state, or zip was not found. Please re-enter and try again. Please enter an address, city, state, or zip. Special characters not allowed in Drug Name field. Location information is unavailable Please enter your address, city, state, or zip in the field provided. The request to Geolocate timed out. Please enter your address, city, state, or zip in the field provided. An unknown error occurred. Please enter your address, city, state, or zip in the field provided. Compare Pharmacy Prescription Drug Prices ScriptSave WellRx is the smart and trusted resource that makes prescription medicines more affordable and easier to manage, because ScriptSave WellRx cares about helping people stay healthy. ScriptSave WellRx is free to join, and we're accepted nationwide at more than 62,000 pharmacies. Enter the prescription drugs you are searching for along with your address or zip code and compare pharmacy prices to find the best prescription drug prices in your area. You can also download our app and use its functionality on the go. How does the ScriptSave WellRx Card work? Simply present your ScriptSave WellRx card at any of the thousands of participating pharmacies nationwide to receive your instant savings. It's that easy! Just show your card to the pharmacist each time you pick up your prescription, whether you're filling for the first time or refilling. There is no paperwork to complete and no limit on usage. How much will I save with the ScriptSave WellRx card? Savings average 54%, and, in some cases, can be 80% or more.* Savings vary based upon the medication and the pharmacy you choose to use. Start saving big on all of your medicine needs with ScriptSave WellRx. Do all pharmacies accept the ScriptSave WellRx Card? ScriptSave WellRx is accepted at 6 Continue reading >>
Instructions For Use
Do not share your NovoLog® Mix 70/30 FlexPen® with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. Who should not take NovoLog® Mix 70/30? Do not take NovoLog® Mix 70/30 if: your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Before taking NovoLog® Mix 70/30, tell your healthcare provider about all your medical conditions including, if you are: pregnant, planning to become pregnant, or are breastfeeding. taking new prescription or over-the-counter medicines, including supplements. Talk to your health care provider about how to manage low blood sugar How should I take NovoLog® Mix 70/30? Read the Instructions for Use and take exactly as directed. NovoLog® Mix 70/30 starts acting fast. If you have type 1 diabetes, inject within 15 minutes before you eat a meal. If you have type 2 diabetes, inject within 15 minutes before or after starting your meal. Do not mix NovoLog® Mix 70/30 with other insulin products or use in an insulin pump. Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to. Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them. Do not reuse or share your needles or syringes with other people. You may give other people a serious infection, or get a serious infection from them. Do not share your NovoLog® Mix 70/30 FlexPen® with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. Who should not take NovoLog® Mix 70/30? Do not take NovoLog® Mix 70/30 if: your blood sugar is too low (hypoglycemia) or you Continue reading >>
Novolog Mix 70-30 Flexpen Insulin Pen
Insulin aspart protamine/ insulin aspart is used along with a proper diet and exercise program to control high blood sugar in people with diabetes . This product is a combination of two man-made insulins: intermediate-acting insulin aspart protamine and rapid-acting insulin aspart. This combination starts working faster and lasts for a longer time than regular insulin. Insulin is a natural substance that allows the body to properly use sugar from the diet. It replaces the insulin that your body no longer produces, thereby lowering your blood sugar . Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke . How to use Novolog Mix 70-30 Flexpen Insulin Pen Read the patient information leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Follow all package directions for proper use/injection/storage of the particular type of device/ insulin you are using. Your health care professional will teach you how to properly inject this medication. If any of the information is unclear, consult your doctor or pharmacist. Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature. Wash your hands before measuring and injecting insulin . Check the product visually for particles, thickening, or clumps before rolling and turning the container. If any are present, discard that container. To avoid damaging the insulin, do not shake the container. Gently roll and turn it between your palms at least 10 times. If using a cartridge or pen, turn it upsid Continue reading >>
Novolog® Mix 70/30 Ifu
NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL Indications and Usage NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL is an insulin analog indicated to improve glycemic control in patients with diabetes mellitus. NovoLog® Mix 70/30 is not recommended for the treatment of diabetic ketoacidosis. The proportions of rapid-acting and long-acting insulins are fixed and do not allow for basal versus prandial dose adjustments. Important Safety Information NovoLog® Mix 70/30 is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® Mix 70/30 or one of its excipients. Never Share a NovoLog® Mix 70/30 FlexPen® Between Patients, even if the needle is changed. Patients using NovoLog® Mix 70/30 vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. Changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. Hypoglycemia is the most common adverse effect of insulin therapy. The timing of hypoglycemia may reflect the time-action profile of the insulin formulation. Glucose monitoring is recommended for all patients with diabetes. To avoid medication errors and accidental mix-ups between NovoLog® Mix 70/30 and other insulin products, instruct patients to always check the insulin label before injection. Severe, life-threatening, generalized allergy, including anaphylaxis, may occur with insulin products, including NovoLog® Mix 70/30. As with all insulins, Continue reading >>
