High-alert Medications - Lantus (insulin Glargine)
The leaflets are FREELY available for download and can be reproduced for free distribution to consumers. Or, if you are a facility or organization, you can order professional pre-printed leaflets shipped directly to you. Extra care is needed because Lantus is a high-alert medicine. High-alert medicines have been proven to be safe and effective. But these medicines can cause serious injury if a mistake happens while taking them. This means that it is very important for you to know about this medicine and take it exactly as directed. Top 10 List of Safety Tips for Lantus When taking your medicine 1. Know your insulin. Lantus is a long-acting insulin that should be injected below the skin once daily as directed by your doctor. On rare occasions, your physician may direct you to take Lantus two times daily. Take Lantus the same time every day. 2. Prepare your insulin. A rapid- or short-acting insulin is often prescribed with Lantus. However, Lantus should never be mixed in the same syringe with other insulins before injection. Do not vigorously shake insulin before use. 3. Don't reuse or recycle. Dispose of used syringes/needles, pens, and lancets in a sealable hard plastic or metal container (e.g., empty detergent bottle, sharps container from your pharmacy). When the container is full, seal the lid before placing it in the trash. Do not reuse or recycle syringes/needles or lancets. 4. Don't share. Even if you change the needle, sharing an insulin pen or syringe may spread diseases carried in the blood, including hepatitis and HIV. To avoid serious side effects 5. Avoid mix-ups. List If you use more than one type of insulin, make sure each vial or pen looks different to avoid mix-ups. Lantus is a long-acting insulin that may look like a rapid- or short-acting insulin. For Continue reading >>
Interactive Dosing Calculator
Lantus® is a long-acting insulin analog indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. Lantus® should be administered once a day at the same time every day. Limitations of Use: Lantus® is not recommended for the treatment of diabetic ketoacidosis. Contraindications Lantus® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to insulin glargine or one of its excipients. Warnings and Precautions Insulin pens, needles, or syringes must never be shared between patients. Do NOT reuse needles. Monitor blood glucose in all patients treated with insulin. Modify insulin regimen cautiously and only under medical supervision. Changes in insulin strength, manufacturer, type, or method of administration may result in the need for a change in insulin dose or an adjustment in concomitant oral antidiabetic treatment. Do not dilute or mix Lantus® with any other insulin or solution. If mixed or diluted, the solution may become cloudy, and the onset of action/time to peak effect may be altered in an unpredictable manner. Do not administer Lantus® via an insulin pump or intravenously because severe hypoglycemia can occur. Hypoglycemia is the most common adverse reaction of insulin therapy, including Lantus®, and may be life-threatening. Medication errors, such as accidental mix-ups between basal insulin products and other insulins, particularly rapid-acting insulins, have been reported. Patients should be instructed to always verify the insulin label before each injection. Severe life-threatening, generalized allergy, including anaphylaxis, can occur. Discontinue Lantus®, treat and monitor until symptoms resolve. A reduction in the Lantus® dose may be re Continue reading >>
Dailymed - Lantus - Insulin Glargin Injection, Solution
A number of drugs affect glucose metabolism and may require insulin dose adjustment and particularly close monitoring. The following are examples of drugs that may increase the blood-glucose-lowering effect of insulins including LANTUS and, therefore, increase the susceptibility to hypoglycemia: oral anti-diabetic products, pramlintide, angiotensin converting enzyme (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, pentoxifylline, salicylates, somatostatin analogs, and sulfonamide antibiotics. The following are examples of drugs that may reduce the blood-glucose-lowering effect of insulins including LANTUS: corticosteroids, niacin, danazol, diuretics, sympathomimetic agents (e.g., epinephrine, albuterol, terbutaline), glucagon, isoniazid, phenothiazine derivatives, somatropin, thyroid hormones, estrogens, progestogens (e.g., in oral contraceptives), protease inhibitors and atypical antipsychotic medications (e.g. olanzapine and clozapine). Beta-blockers, clonidine, lithium salts, and alcohol may either potentiate or weaken the blood-glucose-lowering effect of insulin. Pentamidine may cause hypoglycemia, which may sometimes be followed by hyperglycemia. The signs of hypoglycemia may be reduced or absent in patients taking sympatholytic drugs such as beta-blockers, clonidine, guanethidine, and reserpine. An excess of insulin relative to food intake, energy expenditure, or both may lead to severe and sometimes prolonged and life-threatening hypoglycemia. Mild episodes of hypoglycemia can usually be treated with oral carbohydrates. Adjustments in drug dosage, meal patterns, or exercise may be needed. More severe episodes of hypoglycemia with coma, seizure, or neurologic impairment may be treated with intramuscular/subcutaneou Continue reading >>
Lantus 100 Units/ml Solution For Injection In Solostar Pre-filled Pen
Lantus 100 Units/ml solution for injection in SoloStar pre-filled pen What is a Patient Information Leaflet and why is it useful? The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged. Download Leaflet View the patient leaflet in PDF format Below is a text only representation of the Patient Information Leaflet, the original can be viewed in PDF format using the link above. The text only version may be available from RNIB in large print, Braille or audio CD. For further information call RNIB Medicine Leaflet Line on 0800 198 5000. The product code(s) for this leaflet are: EU/1/00/134/030, EU/1/00/134/037, EU/1/00/134/031, EU/1/00/134/033, EU/1/00/134/036, EU/1/00/134/034, EU/1/00/134/035, EU/1/00/134/032. Lantus 100 Units/ml solution for injection in SoloStar pre-filled pen Package leaflet: Information for the user 100 units/ml solution for injection in a pre-filled pen Read all of this leaflet carefully including the Instructions for Use of Lantus SoloStar, pre- filled pen, before you start using this medicine because it contains important information for you. Keep this leaflet. You may need to read it again. If you have any further questions, ask your doctor, pharmacist or nurse. This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours. If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4. 1. What Lantus is and what it is u Continue reading >>
Bd Ultrafine Iii Mini-pen Needles
Writing Prescriptions for Diabetes Supplies in AIM Clinic (with links to charts from DiabetesHealth.com) Each insulin vial holds 1000 units of insulin; specify # U/dose on RX if possible, to calculate # vials needed Syringe size 3/10 cc (holds up to 30 Units) 1/2 cc (holds up to 50 Units) 1 cc** (holds up to 100 Units) **AIM preferred syringes: BD U-100 Insulin Syringes (easy to read, have ultrafine needle, can keep using as dose rises; #100/box) DISPOSABLE PENS Novolog, NovoLog® Mix 70/30, Levemir® Flexpen Dispense: 5x3 mL (box of 5 pens, Total: 1500 units) Humalog®, Humalog® Mix 75/25, NPH (Humulin N®) Pen Dispense: 5x3 mL (box of 5 pens, Total: 1500 units) Lantus SoloStar® Pen (new) Dispense: 5x3 mL (box of 5 pens, Total: 1500 units) Apidra® Pen (coming soon) REFILLABLE PENS Lantus® Refillable Pens Dispense: 5x3 ml (box of 5 pens, Total: 1500 units) Humalog® Humapen® Memoir *Insulin pens DO NOT come with needles. Need separate RX* **AIM preferred BLOOD GLUCOSE MONITORING DISPENSE: *One Touch Ultra 2 Meter Fast; good for frequent testers; in English and Spanish One Touch Ultra Mini Meter Simple; lightweight; portable; no memory - One Touch Ultra Teststrips Test ___ times/day; disp 50 or 100 strips - Microfine lancets Dispense: 100 lancets Ascensia Contour Meter Simple to use; self-coding; good for slow learners, elderly, low tech - Ascensia Contour Teststrips Test ___ times/day; disp 50 or 100 strips - Ascensia Contour lancets Dispense: 100 lancets Continue reading >>
(insulin Glargine Injection) 300 Units/ml
If you are a patient experiencing problems with a Sanofi US product, please contact Sanofi US at 1-800-633-1610. The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment. Continue reading >>
Tips For Prescribing Insulin Therapy And Diabetes Supplies
There are many different insulin preparations and supplies available in order to create individualized regimens for patients. Here are some tips and a checklist to help avoid getting future calls from pharmacies. · Standard concentration is 100 units/mL (there’s also a 500 units/mL but rarely used) § Before a pen or vial is opened, it won’t expire until the labeled expiration (could be a year) § After a pen or vial is opened, it expires in 28 days o Dispensed as 5 pens (3mL or 300 units each so 1500 units per box). The pharmacy won’t split a box so you can’t prescribe <5 pens. If you do, the pharmacist will round up to one box anyway. Insulin syringe prescribing: Insulin syringes availability: Capacity For doses up to: Gauge Needle length 3/10 mL 30 units 28 1/2" 29 1/2" 31 5/16” 1/2 mL 50 units 28 1/2" 29 1/2" 31 5/16” 1 mL 100 units 27 5/8” 28 1/2" 29 1/2" 31 5/16” Example: You want to prescribe 14 units three times a day. Select 3/10 mL because it holds up to 30 units. If you select a larger than necessary size, accuracy decreases and it becomes harder to read the markings on the barrel. Select the 31 gauge as this is generally more comfortable than thicker gauges. *Note: If someone’s insulin is around 30 units and they’ll be adjusting their dose in the future, give them the 1/2 mL (50 units maximum) since they won’t be able to use the 3/10 mL once they get to 31 units per injection. Insulin pen needles availability Needle Length Gauge Nano 4 mm (5/32”) 32 Mini 5 mm (3/16”) 31 Short 8 mm (5/16”) 31 Original 12.7 mm (1/2”) 29 · Don’t write “Use as directed” on any diabetes supply prescriptions (except glucometer) o Write out the whole directions on each of the prescriptions. Sometimes people go to different pharmacies so if the Continue reading >>
Insulin (medication)
"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[7] The wholesale cost in the developing world is about US$2.39 to $10.61 per 1,000 iu of regular insulin and $2.23 to $10.35 per 1,000 iu of NPH insulin.[8][9] In the United Kingdom 1,000 iu of regular or NPH insulin costs the NHS 7.48 pounds, while this amount of insulin glargine costs 30.68 pounds.[5] Medical uses[edit] Giving insulin with an insulin pen. Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacid Continue reading >>
Medication Errors In Adults: Case #6: Insulin
Medication Errors in Adults: Case #6: Insulin Diabetes Type 2 , Diabetes , Insulin , Safety and Error Prevention Medication errors may occur at any point in the health care system. Obtaining a true estimate of the number of errors is difficult, but preventable medication errors are known to increase patient harm and total health care costs.1 This series will highlight some of the most important drug errors and address methods to decrease the risk of them occurring. In the first article, I addressed a common error associated with warfarin.2 The second article focused on a common error that involved acetaminophen and duplicate therapy.3 In the third article, I addressed a common error associated with duplicate therapy.4 The fourth article discussed a common error with chemotherapy drug interactions.5 In the fifth article, I looked at potential errors related to pharmacotherapy in patients with renal insufficiency.6 This sixth article describes errors associated with insulin. A 54-year-old man with a past medical history of hypertension, hyperlipidemia, and type 2 diabetes mellitus (DM) presents to the clinic for follow-up of his DM. He reports several episodes of hyperglycemia, and his hemoglobin A1c level has increased from 7.1% to 8.2% (American Diabetes Association goal, less than 7.0%). His medications include lisinopril, 10 mg/d; atorvastatin, 20 mg/d; Lantus, 30 units qhs; and Apidra, 10 units tid AC. He reports that he often does not take his vials and syringes with him when he goes out to eat for lunch with his colleagues from the office or to dinner with his wife; however, he is otherwise adherent with his insulin doses. Insulin is one of the medications included on the Institute for Safe Medication Practices List of High-Alert Medications in Community/Ambulator Continue reading >>
Math Calculations With Lantus Insulin
www.TakeRx.com Calculate the total quantity and the total days supply for the following Rx: Lantus 100U/ML 25 units sq qam (1 month supply) ------------------------------------------------------------ The days supply is 30 days as stated by the doctor. The sig says: inject 25 units subcutaneously every morning Now, we need to convert 25 units (U) into mL The insulin ratio is 100 units per 1 mL, that is, 1 mL per 100 units x / 25 U = 1 mL / 100 U x = (25 * 1) / 100 x = 0.25 mL So, the patient will inject 0.25 mL per day. Then, the quantity will be 0.25mL * 30 days which is 7.5mL But, the pharmacist will have to dispense a 10mL vial of Lantus insulin. In other words, one bottle of Lantus insulin has 10mL So, the total quantity to be dispensed is 10 mL Calculate the total quantity and the total days supply for the following Rx: Lantus insulin 30U sq am 20 days ------------------------------------------------------------ The doctor has prescribed Lantus 100U/mL insulin injection. The total days supply is 20 days as stated by the doctor. The sig says: inject 30 units subcutaneously in the morning Now, we need to convert 30 units into mL The insulin ratio is 100 units per 1 mL, that is, 1 mL per 100 units x / 30 U = 1 mL / 100 U x = (30 * 1) / 100 x = 0.3 mL The patient will inject 0.3 mL per day. Then, the total quantity will be 0.3 mL * 20 days which is 6 mL But, one bottle of Lantus insulin has 10 mL and therefore the pharmacist will dispense a 10mL vial of Lantus insulin. So, the total quantity to be dispensed is 10 mL Calculate the total quantity and the total days supply for the following Rx: Lantus 100U/ML cartridge sig: 30 units qam ------------------------------------------------------------ The box has 5 cartridges and each cartridge has 3 mL of insulin. So, if 1 ca Continue reading >>
Pediatric Type 1 Diabetes Mellitus Medication
Medication Summary Insulin is always required to treat type 1 diabetes mellitus. Originally, all insulin was derived from the highly purified pancreatic extracts of pigs and cattle, and this form of insulin is still available. Human insulin was later manufactured using recombinant deoxyribonucleic acid (DNA) technology. "Designer" insulins are also now being produced; they are based on the human molecule and are tailored to meet specific pharmacologic targets, particularly duration of action. Insulin must be given parenterally, and this effectively means subcutaneous injection. [54] Alternatives to injecting insulin have been constantly sought, including an inhaled form of insulin. Several products were in development, and one (Exubera) was licensed for use but failed to generate sufficient market penetration to justify continued production. The search for alternatives continues, including oral sprays, sublingual lozenges, and delayed-absorption capsules. Insulin has 4 basic formulations: ultra ̶ short-acting (eg, lispro, aspart, glulisine), traditional short-acting (eg, regular, soluble), medium- or intermediate-acting (eg, isophane, lente, detemir), and long-acting (eg, ultralente, glargine). Regular or soluble insulin is bound to either protamine (eg, isophane) or zinc (eg, lente, ultralente) in order to prolong the duration of action. Combinations of isophane and regular, lispro, or aspart insulins are also available in a limited number of concentrations that vary around the world, ranging from 25:75 mixtures (ie, 25% lispro, 90% isophane) to 50:50 mixtures. The following image illustrates the activity profile of various insulins. The development of insulin analogues has attempted to address some of the shortcomings of traditional insulin. [55] Insulins lispro, glu Continue reading >>
Insulin And Medication Errors
Ms. Hall is a clinical assistant professor at the University of Oklahoma Health Sciences Center, College of Pharmacy. Dr. Armor is a clinical assistant professor at the University of Oklahoma Health Sciences Center, College of Pharmacy. Both are certified diabetes educators. Insulin is included on the Institute for Safe Medication Practices List of High-Alert Medications.1 Medications appearing on this list represent increased risk of causing significant harm if used in error. Special safeguards to reduce the risk of errors associated with these drugs are recommended, including strategies such as improving access to information about the drugs, standardized ordering, storage, and administration of them, and automated or independent double-checks to verify appropriate administration.1 This article summarizes commonly prescribed insulin products and medication errors encountered in an outpatient diabetes clinic. Managing diabetes with insulin is challenging for patients; therefore, sustained, ongoing support from a health care team is essential. In an effort to raise awareness among health care providers about insulin, case scenarios illustrating common errors and easily overlooked opportunities for educating patients are presented. Insulin In comparison with regular insulin, rapid-acting insulin analogs have a more rapid onset of action and shorter duration of action, reaching higher peak levels and achieving their peak much closer to injection time. They are designed to be administered 10 to 20 minutes before mealtimes. When compared with Neutral Protamine Hagedorn, basal insulin analogs have a prolonged duration of action without a pronounced peak. Premixed insulin analogs are single-peak insulin containing a portion of rapid-acting insulin for meal coverage, plus a pr Continue reading >>
Lantus (insulin Glargine) Side Effects
What Is Lantus (Insulin Glargine)? Lantus is the brand name of insulin glargine, a long-acting insulin used to treat adults and children with type 1 diabetes mellitus and adults with type 2 diabetes mellitus to control high blood sugar. Lantus replaces the insulin that your body no longer produces. Insulin is a natural substance that allows your body to convert dietary sugar into energy and helps store energy for later use. In type 2 diabetes mellitus, your body does not produce enough insulin, or the insulin produced is not used properly, causing a rise in blood sugar. Like other types of insulin, Lantus is used to normalize blood sugar levels. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual dysfunction. Proper control of diabetes has also been shown to reduce your risk of a heart attack or stroke. Lantus is meant to be used alongside a proper diet and exercise program recommended by your doctor. Lantus is manufactured by Sanofi-Aventis. It was approved for use by the Food and Drug Administration (FDA) in 2000 as the first long-acting human insulin administered once a day with a 24-hour sugar-lowering effect. Lantus Warnings You will be taught how to properly inject this medication since that is the only way to use it. Do not inject cold insulin because this can be painful. Always wash your hands before measuring and injecting insulin. Lantus is always clear and colorless; look for cloudy solution or clumps in the container before injecting it. Do not use Lantus to treat diabetic ketoacidosis. A short-acting insulin is used to treat this condition. It is recommended that you take a diabetes education program to learn more about diabetes and how to manage it. Other medical problems may affect the use of this Continue reading >>
Diabetes: Supplies And Teaching
Authors: Jenny Wright, MD, Diane Britt, ARNP Last updated: Testing Supplies: who needs testing? Patients with type 2 diabetes who are well controlled on metformin or diet alone may not need to test their blood sugars daily. However, checking periodically is still useful to identify changes in glycemic control prior to the next A1c test. Testing is useful when: -the patient is taking a hypoglycemic medication (eg sulfonylureas, insulin) -titrating insulin eg titrating insulin glargine to morning blood sugars – don’t have to wait for the next A1c -the patient finds the feedback useful for diabetes control: eg patients learning how foods affect their blood sugar Testing Supplies: how to order Option #1: order individually ‘Meds & Orders’ field -> Glucometer -> select first choice, ‘Blood Glucose Monitor and Supplies’ and all the supplies are pulled in in a bundle; do not specify brand Option #2: EPIC smart set Smart Sets à UWM DIABETES à ORDERS-SUPPLIES Check the ones you want: Blood Glucose Lancets Blood Glucose Monitoring Kit (Do not specify brand) Blood Glucose test strips (On Insulin) (Never specify brand unless asked to) Blood Glucose test strips (No insulin) (Never specify brand unless asked to) Insurance issues: Medicare: Can’t be e-prescribed. Give prescription to patient or have faxed Medicare/Medicaid allowed quantity of test strips: Once a day if not on insulin, 3 a day if on insulin You will ALWAYS get a fax to fill out later, even if you put all required information on your script. Insulin: how to order Glargine: Insulin glargine 100 units / mL solution (aka Lantus) Option #1: Epic smart set: Insulin syringe, ½ cc, 31g, 8mm (5/16). Insulin, typical starting prescription: Insulin glargine 10 units subcutaneous q HS, prescribe vials. Dispense: 1 Continue reading >>
Insulin And The Donut Hole: Lifesaving Drug Often Spikes Medicare Patients' Share Of Costs
Many diabetes patients requiring insulin will end up in the Medicare coverage gap known as the “donut hole,” where they’re responsible for a greater share of the drugs’ costs. When this happens, a patient’s out-of-pocket costs at the pharmacy spike dramatically — for example, from a $40-per-month co-pay to $350 a month. Even worse, some patients struggling with the expenses will drop or stop dosages or switch brands — decisions that can be dangerous to their health if not overseen by their doctor and can actually keep them in the donut hole, costing even more. These erratic costs can be a financial and emotional rollercoaster. Understanding how Medicare Part D Prescription Drug coverage works in regard to insulin can help you plan for price increases and the likelihood that you’ll enter the donut hole coverage gap. To help you, we’ll take you — chronologically — through a calendar year of expenses that a typical patient with diabetes on two forms of insulin may pay, so you can see real-world examples of how the four coverage phases can impact finances. But keep in mind that everyone’s situation can vary greatly, depending on their individual drug plans, other prescriptions and multiple other factors. The four Part D coverage phases First, it’s important to understand how your coverage works. Medicare Part B (medical insurance) does not cover insulin — unless use of an insulin pump is medically necessary. (If you use an external insulin pump, Part B may cover the insulin and the pump.) So having Part D — supplemental prescription drug coverage — is critical for many people to afford injectable insulin. Medicare Part D Prescription Drug coverage has four phases: The deductible phase — you pay the full drug cost until you hit your deductib Continue reading >>
