A Large Difference In Dose Timing Of Basal Insulin Introduces Risk Of Hypoglycemia And Overweight: A Cross-sectional Study
Go to: Abstract Basal insulin should be injected at the same time each day, but people with diabetes sometimes mistime their injections. It is not known whether irregular daily dose timing affects diabetes-related factors. We report here our evaluation of the effects of deviations from a regular dosing schedule on glycemic control and hypoglycemia on patients treated with long-acting insulin (insulin glargine U100). We also consider the effects of ultra-long-acting insulin (insulin degludec) in this context. Methods Nineteen individuals with type 1 diabetes and 58 with type 2 diabetes were enrolled. Demographic data on all participants were retrieved from their medical records. Variation in dose timing was determined as the difference between the time of the earliest mistimed dose and the time of the latest mistimed dose, for each participant, over a 2-week period. All participants completed the Summary of Diabetes Self-Care Activities questionnaire, Problem Areas in Diabetes scale and 5-Item World Health Organization Well-being Index. Glargine U100 was switched to degludec in those individuals with type 2 diabetes who achieved inadequate glycemic control or suffered from frequent hypoglycemic episodes or who required two injections per day, and changes in hemoglobin A1c level and frequency of hypoglycemic episodes during the 12-week period were compared. A greater difference in dose timing was related to a higher frequency of hypoglycemic episodes and overweight in persons with type 2 diabetes. Smoking, drinking and living alone were independently associated with a greater difference in dose timing. Insulin degludec decreased the frequency of hypoglycemia and improved glycemic control in participants whose dose mistiming was >120 min. Fixed dose timing should be employ Continue reading >>
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Forgot To Take Lantus..what Should I Do?
Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. I was at a party the other night, and I honestly forgot to take my Lantus. I wasent quite sure what to do the next morning, so I just decided to check my sugars at random parts of the day, and just use my correction dosage. But I also realized that I am still in the honeymoon period, so its not like I had NO insulin in me whatso ever. If you guys have any suggestions or better steps to take for me to take if I ever forget to take it again, pleaseeeee tell me. Thanks If it were me, I would just monitor and cover all day until my normal shot time. I'd probably also be taking it twice a day, as from what I read it seems to work better that way, and would also cut down on the severity of a missed shot. It has been awhile since I used lantus, but I probably would have gone with a split dose and then checked all day long and corrected. I've done this before when I was taking my Lantus before bed. Woke up about 3AM and remembered that I had not taken my shot before bed. Checked my bg to be sure and sure enough, middle 300's !!! Called one of our local ER's and to tell you the truth, they were NOT much help. When I explained my situation, their response was "Well, we don't think it would hurt you to take it now but we really aren't advising you one way or the other." I was like WTF?? Aren't they supposed to be there to help you?? I finally was able to get in touch with my CDE through the hospital and he told me to go ahead and take it but to monitor the next 24 hrs very closely. My suggestion would be to discuss this with your endo. It's best to know what to do before a situation arises. i'm pretty s Continue reading >>
Lantus Side Effects
Generic Name: insulin glargine (IN su lin GLAR gine) Brand Names: Basaglar KwikPen, Lantus, Lantus Solostar Pen, Toujeo SoloStar What is Lantus? Lantus (insulin glargine) is a man-made form of a hormone that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Lantus is used to improve blood sugar control in adults and children with diabetes mellitus. Lantus is used to treat type 1 or type 2 diabetes in adults, and type 1 diabetes children who are at least 6 years old. Some brands of insulin glargine are for use only in adults. Carefully follow all instructions for the brand of insulin glargine you are using. Important information You should not use Lantus if you are having an episode of hypoglycemia (low blood sugar), or if you are in a state of diabetic ketoacidosis. Never share a Lantus injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another. Lantus is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels. Before taking this medicine You should not use Lantus if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar). Lantus is not approved for use by anyone younger than 6 years old, and should not be used to treat type 2 diabetes in a child of any age. To make sure Lantus is safe for you, tell your docto Continue reading >>
Insulin Glargine
Why has my veterinarian prescribed this medicine? Insulin glargine is a long-acting insulin used in cats with diabetes mellitus to help regulate blood sugar. How do I give this medication? "An overdose could seriously harm your cat." This medication is injected under the skin (subcutaneously) usually twice a day. Read the label carefully. Allow the medication to come to room temperature before injecting. This medication does not need shaking or swirling. Ensure your veterinarian has demonstrated the proper technique for withdrawing the insulin and proper injection technique. Do not dilute or mix glargine insulin with diluents or other medications. Measure the dose with reasonable care. Double-check the dose in the syringe. An overdose could seriously harm your cat. The dose is generally only a few units of insulin and the gradations on a syringe are tiny. Try to give this medication at about the same time each day. Do not give the pet more insulin than directed and do not give more often than directed. Try not to miss giving any doses. It is a good idea to keep two vials of insulin on hand, just in case one is broken or you run out over a weekend or holiday. Be aware of your pet's normal behavior. This will help determine when something is wrong. If your pet is not acting normal, suspect low blood sugar (hypoglycemia). You may wish to carry packets of honey, packets of sugar or a small bottle of corn syrup for emergency administration when leaving home with your pet. What do I do if I miss giving a dose? Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. NEVER give the cat two doses at once. How do I store this medicine? Keep this medicine out of reach of children. Store the insulin in Continue reading >>
Lantus (insulin Glargine)
What is it used for? How does it work? Lantus vials, Lantus SoloStar pre-filled pens and Lantus penfill cartridges (for use with ClikSTAR or Autopen 24 pens) contain the active ingredient insulin glargine. They are used to treat diabetes. People with diabetes have a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar (glucose) in the blood. People with type one diabetes need to have injections of insulin to control the amount of glucose in their bloodstream. Insulin injections act as a replacement for natural insulin and allow people with diabetes to achieve normal blood glucose levels. Insulin injections work in the same way as natural insulin, by binding to insulin receptors on cells in the body. Insulin causes cells in the liver, muscle and fat tissue to increase their uptake of glucose from the bloodstream. It also decreases the production of glucose by the liver, and has various other effects that lower the amount of glucose in the blood. Lantus contains a type of insulin called insulin glargine. This is known as a long-acting insulin. When injected under the skin it starts working within two to three hours and produces a steady effect for 25 hours. It is used to help provide background control of blood glucose throughout the day. Insulin glargine is normally used in combination with a short-acting insulin, which is given before meals to control the increasing blood glucose levels after eating. It is important to monitor your blood glucose regularly and adjust your insulin dose as required. Your doctor or diabetic team will explain how to do this. Keeping your blood glucose level as close to normal as possible, and not too high or too low, significantly reduces the risk of Continue reading >>
Missing Insulin Injections
Tweet Missed insulin injections are much more of a pain than the injections themselves and can cause a headache as to what effect a late injection will have and what dose should be administered. We look at this common problem and provide some guidance. Always remember that if you are at all unsure what to do, you should contact your health team for advice rather than risk making a mistake. In this article, when it says contact your health team, note that you may need to contact your out of hours service if your health team is not available. Common causes of missed injections Commonly cited reasons for missed injections include: Forgetting to take insulin Oversleeping Not having your injection kit with you Running out of insulin Having a fear of needles Deliberately missing insulin If you have problems with forgetting injections, see our forgetting injections guide dedicated to help prevent problems with forgetting to inject and if you forget whether you have injected or not. What to do if an insulin injection is missed There is not a set rule of what to do if an injection is missed as it can depend on how long ago the injection was meant to be administered and what type of insulin was to be taken. We provide some general tips but if you are in doubt, it is best to consult your health team and follow their advice. If long term/basal insulin was forgotten If you forget to take your long term insulin (basal insulin) and you realise relatively soon, it should usually be fine to inject your usual dose if the dose is given within 2 hours of when it should have been done. In this case, you’ll need to be aware that the injection was taken later and so the insulin will also be active in your body later than it would usually be. In some cases this could increase the chance of h Continue reading >>
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Missed Pm Lantus | Diabetic Connect
I did not give myself the 60 units of Lantus last night. Could that be the cause of a high BG late afternoon and evening. After lunch of a salad w/low carb salad dressing; I was at 200 at 4:30 (2 hour after lunch; ate lunch late). Before dinner of a salad (9:30), I was 194. 2 hrs later I'm 197. As a Type 1, nearly 50 years now (: (, while very rarely, I have had this issue. Cannot tell from your profile, though a T2 if you use short acting insulins or not? I suspect you do not, but no proof one way or another until we hear back. The SHORT answer, try not to make this mistake a second, third, forth, + time. It will not kill you, but it is a baaaad habit to get into, try and avoid this game. It is likely that there is some residual lantus in your body which did not get totally absorbed. Not lots and lots, but a few units likely. In that way, you very likely have some insulin on board, if only a couple units??? You could call the doctor, if the numbers worried you enough, but given the numbers you provided, its not remotely high enough to worry about in the least. 500, HI then I might get concerned. But 200's, 300's not too much. Try not to let it happen again. If you use short acting, I would use whatever formula you use/were given, and cover the high(s), until its time for your lantus again. If you don't have short acting Try and take it easy with excess carbs that day, wait until you would normally take it again. No serious harm, try not do it too often!!! Lantus provides you with "Basal insulin", a small amount of insulin that your body would normally secrete throughout the day/night. Lantus usually lasts 24 hours. Do you take another fast-acting (e.g. Humalog or Novolog) insulin to handle the food you eat? This is called "Bolus" insulin. When did you realize you skip Continue reading >>
Lantus
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. (lant-us) What is in this leaflet It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator. All medicines have risks and benefits. Your doctor has weighed the risks of you using Lantus against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. What Lantus is used for Lantus is used to reduce high blood sugar (glucose) levels in people with diabetes mellitus. Lantus is a modified insulin that is very similar to human insulin. It is a substitute for the insulin produced by the pancreas. Lantus is a long-acting insulin. Your doctor may tell you to use a rapid-acting human insulin or oral diabetes medication in combination with Lantus. Ask your doctor if you have any questions about why Lantus has been prescribed for you. Before you use Lantus When you must not use Lantus Some of the symptoms of an allergic reaction may include: If you have a lot of hypos discuss appropriate treatment with your doctor. After the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If you use Lantus after the expiry date has passed, it may not work as well. If it has expired or is damaged, return it to your pharmacist for disposal. If the product appears cloudy, discoloured or contains particles, or if the injection pen/cartridge/vial appears damaged. If you are not sure whether you should start using this medicine, talk to your doctor. There is no experience with the use of Lantus in children less than 6 years. Before you start to use Lantus Tell your doctor if you have allergies to any other medicines, foo Continue reading >>
Getting The Right Dosage
Even for those on Lantus® for a while, it may take a little time to get to the right dose of insulin. Your doctor may change your Lantus® dose several times in the first few weeks. This is to be expected. For best results, keep taking your Lantus® as prescribed, and keep talking to your doctor. What if You Miss a Dose? Your doctor will guide you on when to take Lantus®. Ask him or her what to do if you forget to take your insulin, so you can be prepared in advance in case it ever happens. Here are a few ways to remember to take your Lantus® once-a-day: 3 Helpful Tips Make yourself a reminder If you take your Lantus® at night, it might also be a good idea to leave yourself a note on your nightstand as a way to remember. If you take it in the morning, put your supplies where you can't miss them—next to your toothbrush, for example. Keep out of reach of children. Add it to your other daily "to dos" Many people take Lantus® right after brushing their teeth in the evening or while making breakfast in the morning. Set an Alarm Some people set alarms on their wristwatches or mobile devices to remind them when to take their Lantus®. “We changed doses a couple of times when I started on Lantus®, until we found the right amount for me.” Continue reading >>
Missed Insulin | Feline Diabetes Message Board - Fdmb
This morning I tried to give my 14 year old cat his insulin injection twice and he jumped out of my lap. He gets Lantus insulin 1 unit twice a day. Is it ok to wait until tonight to give him his injection. I have been doing it at the scruff of the neck, would there be a better place to do it? Our first diabetic Nigel was very cooperative but after 18 months his numbers went up. Before we upped his dose I thought he might be getting scar tissue (that's doubtful) and when I switched to his back shoulder everything went back to normal. Noah gets his in the shoulder, not enough meat on his scruff. The missed dose, it's 2:40 here. Check his numbers now. I can't keep Noah on a 12/12 schedule and I would give him a 1/4 dose if I were really late but that's only Noah. I can't ethically advise either way, best to watch his levels and at least do him early tonight. Yes, you can wait until tonight. You might have to change the location of the injections. I sit on the bath mat on the floor in my bathroom, door closed. I put my cat between my legs facing forward. If getting down on the floor won't work, maybe on the couch or the bed? You can use the scruff for now until you're sure you have a secure way of corralling him. I see you joined today which doesn't mean you don't know what you're doing. We have an expression, fur shot, which means a complete miss. I've seen vets do this with vaccinations, squirt right across the room. It's not a tragedy as long as you're on top of things. The 12/12 thing? I've broken all the rules as far as food, eating schedules, strict dosing advice. That only comes after years of knowing what works and what doesn't. This isn't medical school, you can't fail. Kris & Teasel are correct, you can miss a shot without killing you cat. It's one part rocket su Continue reading >>
Lantus Patient Information Including Side Effects
Brand Names: Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen Generic Name: insulin glargine (Pronunciation: IN su lin AS part, IN su lin AS part PRO ta meen) What is the most important information I should know about insulin glargine (Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen)? What should I discuss with my healthcare provider before using insulin glargine (Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen)? What is insulin glargine (Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen)? Insulin glargine is a man-made form of a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting form of insulin that is slightly different from other forms of insulin that are not man-made. Insulin glargine is used to treat type 1 or type 2 diabetes. Insulin glargine may also be used for purposes not listed in this medication guide. What are the possible side effects of insulin glargine (Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen)? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Hypoglycemia, or low blood sugar, is the most common side effect of insulin glargine. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar. Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin glargine. This is not a complete list of side effects and others may occur. Call Continue reading >>
Missed Lantus Last Night>>
D.D. Family 44 Years Old Type 2 Since October 2009 I fell asleep last night, so tired, and missed my lantus dose. What do you all do if you accidently miss your nightly shot? Should I take it this morning or wait until nighttime usual shot? I have diabetes, IT DOES NOT HAVE ME !!!!! Lisinopril 40mg, Metformin 1000mg 2 x day, and Lantus 18u 1x at night Friend T1 since febuary 1997, on pump started 2nd 08.10 do you take more then one shot a day of lantus? if it was me i would be feeling pretty rotten now, and would of proberly had a bad night getting up to pee every hour! if it was me i would take some rapid to lower sugar as mine would be very high by this point, and take my second dose of levermir soon as! Friend Diagnosed '91-Type 2 Lantus Pen approx 47-50units That is a Q I had not thought of! I take mine at night to bring down skyhigh fastings...yet if I skipped it my meal numbers would go coo coo too. For today you could just really low carb it and wait for your usual night dose (that's what I would do) or call the Doc. D.D. Family 44 Years Old Type 2 Since October 2009 Woke up with 142 bg..not too bad. I am going to call endo in a few hours and ask her. She may very well tell ne to just hold on till tonight. Thanks alotan I usually worry about double dosing by accident, not missing a shot. Take 1/2 now. eg. if you take 14 units take 7 now. Then tonight take 10 units. The following night go back up to 14 units. Friend Dexcom 7+, combined Omnipod and Lantus therapy I never get into splitting the dose--it was hard to get it back on track when I was one shot a day. -maintained a basal regimen with small humalog shots every 3 hours--it's not perfect, but it got me through -kept one bottle of lente or NPH in the frig so i could take a small shot of that to give me basal Continue reading >>
What Happens If I Miss A Dose Of Lantus?
Lantus should be taken at the same time every day. Your doctor will give you instructions on what to do if you miss a dose. Maintaining a proper balance of insulin and sugar in the body is important to avoid possibly serious side effects from hypoglycemia or hyperglycemia, including coma and death. You should not take more than one dose of Lantus in a 24 hour period unless your doctor instructs you otherwise. Chemical Toxins Relationship Abuse Diabetes Complications Body Contouring Your Lifestyle The Five Senses Stages Of Colon Cancer Patient Education For Improving Rx Drug Adherence Your Mind Male Reproductive System Parts Parenting Teens Morning Sickness & Pregnancy Mental Health Therapies Sharecare Bladder Cancer Obsessive Compulsive Disorder Digestive Diseases Schizophrenia Hydrocephalus Conception Achieved (Pregnancy) Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs. Continue reading >>
Lantus 100 Unit/ml Subcutaneous Solution
Insulin glargine is used with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.Insulin glargine is a man-made product that is similar to human insulin. It replaces the insulin that your body would normally make. It acts longer than regular insulin, providing a low, steady level of insulin. It works by helping blood sugar (glucose) get into cells so your body can use it for energy. Insulin glargine may be used with a shorter-acting insulin product. It may also be used alone or with other diabetes drugs. Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist.Follow all package directions for proper use/injection/storage of the particular type of device/insulin you are using. Your health care professional will teach you how to properly inject this medication. If any of the information is unclear, consult your doctor or pharmacist.Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature (see also Storage section). Wash your hands before measuring and injecting insulin. Before using, check the product visually for particles, thickening, or clumps. If any are present, discard that container. Insulin glargine should be clear and colorless. To avoid damaging the insulin, do not shake the container.The dosage is based on your medical condition and response to treatment. Measure each dose carefully, and Continue reading >>
Insulin Glargine - Injection
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Insulin glargine is used with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Insulin glargine is a man-made product that is similar to human insulin. It replaces the insulin that your body would normally make. It acts longer than regular insulin, providing a low, steady level of insulin. It works by helping blood sugar (glucose) get into cells so your body can use it for energy. Insulin glargine may be used with a shorter-acting insulin product. It may also be used alone or with other diabetes drugs. Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist. Follow all package directions for proper use/injection/storage of the particular type of device/insulin you are using. Your health care professional will teach you how to properly inject this medication. If any of the information is unclear, consult your doctor or pharmacist. Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature Continue reading >>
