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Lack Of Insulin Causes Hypoglycemia

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Lack Of Hypoglycemic Symptoms And Decreased Beta-adrenergic Sensitivity Ininsulin-dependent Diabetic Patients.

1. J Clin Endocrinol Metab. 1988 Feb;66(2):273-8. Lack of hypoglycemic symptoms and decreased beta-adrenergic sensitivity ininsulin-dependent diabetic patients. Berlin I(1), Grimaldi A, Landault C, Zoghbi F, Thervet F, Puech AJ, Legrand JC. (1)Department of Clinical Pharmacology, Hpital Piti-Salptrire, Paris, France. Plasma epinephrine, norepinephrine, and dopamine responses were studied ininsulin-dependent diabetic patients at rest, on standing and duringinsulin-induced hypoglycemia. beta-Adrenergic sensitivity was evaluated by theisoproterenol sensitivity test. Five men who had adrenergic symptoms duringhypoglycemia and no severe hypoglycemic accidents (coma, seizures) (group A) and five men who had repeated severe hypoglycemic accidents but lack of adrenergicsymptoms of hypoglycemia (group B) were studied. The mean resting plasmaepinephrine was lower in group B (147 +/- 22 pmol/L, SEM) than in group A (398+/- 98 pmol/L, P less than 0.02). On standing plasma epinephrine increasedsignificantly in both groups. During hypoglycemia blood glucose decreasedidentically in the two groups; plasma epinephrine and norepinephrine increasedsignificantly and to the same extent in both groups; Continue reading >>

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  1. rcs451

    insurance cover testing strips

    I guess I never thought about testing strips being covered by insurance until the fellow in the drug store asked about insurance for the testing strips... hmmm? Those do add up.
    So are you getting insurance to pay for the testing strips? Do you simply contact the Dr. and ask them to send a prescription to the drug store for a month or two of testing strips?
    Thanks
    Ron

  2. dobelady

    Originally Posted by rcs451
    I guess I never thought about testing strips being covered by insurance until the fellow in the drug store asked about insurance for the testing strips... hmmm? Those do add up.
    So are you getting insurance to pay for the testing strips? Do you simply contact the Dr. and ask them to send a prescription to the drug store for a month or two of testing strips?
    Thanks
    Ron When I went in with my initial perscriptions, my Dr wrote one for testing strips and lancets. I was happily surprised that I pay nothing for either. My insurance covers them 100%. At $100.00 (USD) for a box of 100, I was very thankful. However, my Dr doesn't have me nearly testing as much as I do. They initially had me only testing 1 a day and I told him it was not enough so he bumped it up to 2x a day and I do it 4-5 times a day. So far my insurance hasn't balked at the refills.
    Oh and FYI it's United Health Care

  3. jason.rohde

    I get a 4 month supply (600 strips) every 3 months and I pay like $20.00, insurance (Blue Cross Blue Shield of Illinois)covers the rest. I use a mail order service so they are cheaper and automatically refilled and I always have a surplus of strips.

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Heoc 101, Pharmacology, Ch 15

metabolism, including body temperature and weight, blood and bone calcium by secreting calcitonin blood calcium level remains high and bone calcium level remains low, leading to bone fractures both energy and calcium storage, but prescriber may order only calcium supplements surface of thyroid gland and are responsibile for concentration of sodium and calcium in blood and urine; also help regulate calcium balance parathyroid glands:counteract calcitonin: with parathormone, which pulls calcium out of bones and into bloodstream melatonin, in response to input from eyes to sleep; in darker hours of night and wnter, we tend to feel sleepier sleep is impaired, and melatonin or barbiturates may be RX to correct this disorder meds used to treat endocrine system disorder: 3 categories: 1. meds for thyroid & parathyroid disorders individual cells to work; it's an "on" switch for the body stimulate every tissue in body to produce proteins and increaes amount of oxygen used by cells patient has less energy, and every cel in body is affected tachycardia, hyperthermia, chest pain, sweating, weakness, heart failure, anxiety, shortness of breath, disorientation thyroid can be inhibited from secr Continue reading >>

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  1. Jean and Charcoal

    Hi Everyone,
    My vet told me I could give B-12 once a week to my old girl, Ketchie, who is 17. When I had her to the vet's a week and a half ago, my vet gave Ketchie fluids, and she drew up the B-12 into a syringe that was marked with ml's. I have some 100 unit diabetic syringes, and wondered if anyone knows how many units would I draw into that syringe to equal .2ml's ?
    Thanks, if anyone can help me out here. I have hunted on the internet, but can't seem to find a conversion chart for that.
    Jean and Charcoal (GA)

  2. squeem3

    Re: Giving B-12 in 100 unit Insulin Syringe, how much is .2
    Jean and Charcoal said:
    . I have some 100 unit diabetic syringes, and wondered if anyone knows how many units would I draw into that syringe to equal .2ml's ?
    Measure to the 20 unit line for 0.2 ml.
    1 ml (1 cc) = 100 units
    0.5 ml (1/2 cc) = 50 units
    0.1 ml = 10 units
    0.01 ml = 1 unit

  3. Jean and Charcoal

    Re: Giving B-12 in 100 unit Insulin Syringe, how much is .2
    Thanks so much!!!
    Also, I finally found a site with the info, just now, in case anyone needs to see the conversion chart:
    http://www.petplace.com/dogs/how-to-convert-u-100-insulin-to-milliliters/page1.aspx

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Minireview: Glucagon In The Pathogenesis Of Hypoglycemia And Hyperglycemia In Diabetes

Minireview: Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes Division of Endocrinology, Metabolism, and Lipid Research, Washington University, St. Louis, Missouri 63110 Address all correspondence and requests for reprints to: Philip E. Cryer, M.D., Campus Box 8127, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, Missouri 63110. Search for other works by this author on: Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 10391048, Philip E. Cryer; Minireview: Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes, Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 10391048, Pancreatic islet -cell glucagon secretion is critically dependent on pancreatic islet -cell insulin secretion. Normally, a decrease in the plasma glucose concentration causes a decrease in -cell insulin secretion that signals an increase in -cell glucagon secretion during hypoglycemia. In contrast, an increase in the plasma glucose concentration, among other stimuli, causes an increase in -cell insulin secretion that signals a decrease, or at least no change, in -cell glucagon secretion after a meal. In absolute endogenous insul Continue reading >>

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  1. TimmyMac

    This is a new one. My new Lantus pen doesn't seem to want to inject more than a unit at a time. If I put pressure on the plunger, it will only click once. I had to let off the plunger and press it again 16 times to take my nightly Injection. I'm honestly not too sure how much insulin I even got after all that. I tried it with 3 separate needles in 3 different injection locations, so it's not a scar tissue or needle issue.

    What should I do about this? Can I get a replacement?

  2. Brian_BSC

    It sounds like you pen is broken. Something inside is physically broken. I have had than happen with a few pens. If you filled your prescription at a local pharmacy you should be able to take it in and show it to them and they should be able to replace, perhaps immediately. If you use a mail order pharmacy the process will likely be more difficult, but they should be able to replace it as well. Finally, if all else fails you should be call Sanofi and get some help.

  3. JoAnn2

    If you cannot get a replacement, what I have done in the past, is use a syringe and pull the amount I need from the pen and inject it that way. I do that with pens any way because after it will no longer allow further dosing, there is usually another 25 units that can be retrieved from the pen, as there is more than 300 units in the pens. (I am very frugal with the insulin.) Hope you get this resolved.

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    1. J Clin Endocrinol Metab. 1988 Feb;66(2):273-8. Lack of hypoglycemic symptoms and decreased beta-adrenergic sensitivity ininsulin-dependent diabetic patients. Berlin I(1), Grimaldi A, Landault C, Zoghbi F, Thervet F, Puech AJ, Legrand JC. (1)Department of Clinical Pharmacology, Hpital Piti-Salptrire, Paris, France. Plasma epinephrine, norepinephrine, and dopamine responses were studied ininsulin-dependent diabetic patients at rest, on standing ...

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