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Lack Of Insulin

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Diabetes Causes

Diabetes is a chronic disease that occurs because the body is unable to use blood sugar (glucose) properly. The exact cause of this malfunction is unknown, but genetic and environmental factors play a part. Risk factors for diabetes include obesity and high levels of cholesterol. Some specific causes are discussed below. Lack of insulin production This is primarily the cause of type 1 diabetes. It occurs when insulin-producing cells are damaged or destroyed and stop producing insulin. Insulin is needed to move blood sugar into cells throughout the body. The resulting insulin deficiency leaves too much sugar in the blood and not enough in the cells for energy. Insulin resistance This is specific to type 2 diabetes. It occurs when insulin is produced normally in the pancreas, but the body is still unable move glucose into the cells for fuel. At first, the pancreas will create more insulin to overcome the body’s resistance. Eventually the cells “wear out.” At that point the body slows insulin production, leaving too much glucose in the blood. This is known as prediabetes. A person with prediabetes has a blood sugar level higher than normal but not high enough for a diagnosis of Continue reading >>

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Popular Questions

  1. molson1959

    lack of insulin or insulin resistance

    Greetings members,
    As a newbie T2, i have lots of questions as i am sure a lot of you had.
    Can someone tell me in general terms how treatment differs with the two distinct diabetes problems mentioned above.
    I have looked through the forums but did not find what i was looking for, if this has been covered previously, accept my opologizes and perhaps direct me to the correct thread
    Thanks in advance
    mike

  2. jwags

    Welcome Mike to DD. Lack of insulin or insulin insufficiency can be tested by a C Peptide test. Insulin resistance can also be tested with a C Peptide. If you have a high level of insulin and high fasting numbers you probably are insulin resistant. A very low number may indicate lack of insulin. Once your beta cells are damaged they usually don't regenerate and you will probably need injected insulin.

  3. Lynnw

    From what I've read, a lot of doctors don't make the distinction between IR and insulin insufficiency. To my doctor, high blood sugar is the issue...WHY it's high is irrelevant. He started going down his list of medications, starting with Metformin. If it didn't work, he'd shrug and try the next drug on the list. I had to beg him to do tests (except lipids...he was crazy for lipid tests, even though mine were good every time). I want answers, so I wasn't happy with that. Seems to me you'd want to know WHY it's high to determine the best treatment.

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