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Is Regular Insulin Short Acting?

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Insulin Lispro: A Fast-acting Insulin Analog

Research has established the importance of maintaining blood glucose levels near normal in patients with type 1 (insulin-dependent) diabetes mellitus. Short-acting insulin analogs are designed to overcome the limitations of regular short-acting insulins. Compared with regular human insulin, the analog insulin lispro offers faster subcutaneous absorption, an earlier and greater insulin peak and a more rapid post-peak decrease. Insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, and peak levels occur 30 to 90 minutes after administration. Duration of activity is less than five hours. Rates of insulin allergy, lipodystrophy, hypoglycemia and abnormal laboratory test results are essentially the same in patients using insulin lispro and in those using regular human insulin. The Diabetes Control and Complications Trial (DCCT)1 established the importance of maintaining near-normal blood glucose levels in patients with type 1 (insulin-dependent) diabetes mellitus. In these patients, intensive therapeutic regimens have been found to delay the onset and reduce the progression of microvascular complications by 50 to 75 percent as compared with conventi Continue reading >>

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Popular Questions

  1. janey.1971

    Hi everyone. I hope you will be able to help me. Last week, I got diagnosed with Gestational Diabetes. This is my fourth pregnancy. I got GD in my second pregnancy but not in the other 2. The first time round, I controlled it by diet alone with no problems. My baby was 7lbs 12ozs which was absolutely fine.
    This time, after my GTT, my levels were quite high. The Diabetic Midwife put me on a strict diet straight away and after a few days contacted me to say they were still too high and that I needed to go on Metformin. I am not that happy about this as every website I have been on has said that these tablets shouldn't be taken in pregnancy. I'm at a loss with what to do now. I'm almost 40 and this is my last child and I'm concerned taking these tablets will cause problems for the baby.
    I spoke to a Pharmacist about these tablets and he couldn't help either. I would be grateful if anyone could advise me on these tablets and what the possible side effects for the baby are and whether or not they are indeed safe.
    Thank you
    Jane

  2. cugila

    From my own reading into this subject, Metformin has been shown to improve Insulin sensitivity and may also help with weight loss. Apparently it does cross the placenta but but trials have shown no (serious) adverse effects.
    In one study in 2007 (MiG 2007) it was suggested that Metformin was safe to use and that there was no evidence of any increase in complications and/or birth defects. It was approved by NICE for use in pregnant Diabetic Women.
    If you are concerned then this is something you should discuss more fully with your Diabetic Midwife. You are obviously under enough stress without adding more. There have been some posts here about this before, in one instance I remember that the member persuaded her Consultant that she could manage using diet alone. She had a fine healthy baby !
    Best of luck to you and your baby whatever you decide to do. If you do go down the diet route, then the advice that Sue and I usually hand out to newly diagnosed Diabetic's may be of some benefit to you in taking better control of those Bg numbers. We could post it for you if you so wish ?
    Ken

  3. janey.1971

    Thank you very much for your reply. I'm just so confused about what to do. I am awaiting a callback from the Diabetic Midwife as I need reassurance before I attempt to take these tablets.
    I would be very grateful if you could send any information that you have as it is all quite confusing about what I can and can't eat. Do you have a list of foods which are ok to take for Diabetics. I thought vegetables were fine but I have been told to limit them plus fruit too.
    Thank you
    Jane

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