Diabetes Prescription Insulin Medications
font size A A A 1 2 3 4 5 Next For related diabetes medication information: Prescription Oral Diabetes Medications - on RxList What is the diabetes medication insulin and how does it work? Insulin is a hormone that is produced by certain cells in the pancreas called beta cells. Insulin helps the body use blood glucose (a type of sugar) for energy. When we eat and absorb food, glucose levels rise and insulin is released. Some people can't make insulin; those people are said to have type 1 diabetes. A person with type 2 diabetes can make insulin, but the body doesn't respond well to insulin; they are said to have “insulin resistance.” For what conditions is the diabetes medication insulin used? Insulin is always necessary for type 1 diabetes because the body has no internal source of insulin. People with type 2 diabetes may also need insulin, particularly those who have difficulty controlling their diabetes with oral medications. Are there differences among types of insulin? Insulins differ based on three characteristics: how quickly they start to work, when they reach their peak effect, and how long they last. Rapid-acting insulins start working in less than 15 minutes, peak in an hour, and continue working for another two to four hours. Regular, also known as short-acting insulin, takes about 30 minutes to reach the bloodstream. Its peak effect is in about two to three hours, and its effect lingers for three to six hours. Intermediate-acting insulin reaches the bloodstream in two to four hours, peaks in four to 12 hours, and works for up to 18 hours. Long-acting insulin takes six to 10 hours to start working, but it lasts for 20-24 hours. Many people with diabetes may use different types of insulins to get the optimal effect on their blood sugar levels. Premixed ins Continue reading >>
A Complete List Of Diabetes Medications
Diabetes is a condition that leads to high levels of blood glucose (or sugar) in the body. This happens when your body can’t make or use insulin like it’s supposed to. Insulin is a substance that helps your body use the sugar from the food you eat. There are two different types of diabetes: type 1 diabetes and type 2 diabetes. People with both types of diabetes need medications to help keep their blood sugar levels normal. The types of drugs that can treat you depend on the type of diabetes you have. This article gives you information about drugs that treat both types of diabetes to help give you an idea of the treatment options available to you. Insulin Insulin is the most common type of medication used in type 1 diabetes treatment. It’s also used in type 2 diabetes treatment. It’s given by injection and comes in different types. The type of insulin you need depends on how severe your insulin depletion is. Options include: Short-acting insulin regular insulin (Humulin and Novolin) Rapid-acting insulins Intermediate-acting insulin Long-acting insulins Combination insulins NovoLog Mix 70/30 (insulin aspart protamine-insulin aspart) Humalog Mix 75/25 (insulin lispro protamine-insulin lispro) Humalog Mix 50/50 (insulin lispro protamine-insulin lispro) Humulin 70/30 (human insulin NPH-human insulin regular) Novolin 70/30 (human insulin NPH-human insulin regular) Ryzodeg (insulin degludec-insulin aspart) Amylinomimetic drug Pramlintide (SymlinPen 120, SymlinPen 60) is an amylinomimetic drug. It’s an injectable drug used before meals. It works by delaying the time your stomach takes to empty itself. It reduces glucagon secretion after meals. This lowers your blood sugar. It also reduces appetite through a central mechanism. Most medications for type 2 diabetes are o Continue reading >>
Why Isn't Insulin Offered As A Generic Prescription Drug, Even Though It's Been Out For Longer That The Seven Year Patent Time Required For Other Drugs?
The pharmaceutical companies play all sorts of games to keep their patents. They change the formulation slightly, the delivery method, or even the indications for this. They then try to sue anyone who tries to make a generic copy, even when their patent expires. Sometimes, they pay off generic drug makers not to make a drug (illegal, but we know they do this anyways), buy a generic drug maker to prevent this, or even make the generic brand itself, alongside with the name brand. The drug companies in the USA have free reign to charge whatever they want for medication without government interference. When animal insulins were used, a bottle of NPH or Regular insulin cost about $15-$20. When synthetic humulin came out, it probably was about $40-$45. Now, the cost is approaching $200 a bottle sometimes. Why? Because our government is in the pocket of Big Pharm. Absolutely ludicrous! Continue reading >>
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What Drugs Can You Do With The Orange Insulin Needles?
The insulin syringes are used for most of the IV drugs. This includes meth, heroin, cocaine, ketamine, DMT, and most water soluable drugs. There are drugs that are taken intramuscularly with the large 3mil syringes. Most people are not really aware of these, they are niche drugs like DBol and similar substances. I have a friend who cycles test and DBol and when he brought out his syringes I thought he was trying to make a rabies shot. The needle must have been a 19 gauge or something. It looked like a spear. Anyway, the drug that's being taken intravenously with the 28 or 29 gauge insulin syringes can normally be identified by the process of preparing the dose. With heroin, the user will put the water in a little metal cup and add the drug to it. They will then heat it with a flame until it's all dissolved. They then add a ball of cotton and draw up a brownish liquid into the syringe. With meth the drug is mixed with water and stirred until it is all dissolved. The cotton is sometimes used but not necessary in most cases. The liquid is clear. With cocaine it is prepared like heroin but the liquid is clear or slightly off white. Ketamine is prepared like meth but it can be used IM, SC, and IV without any problems. Meth can only be done IV. Ketamine is an offwhite color which appears cloudy. Continue reading >>
Can Diabetics Use Insulin As A Performance-enhancing Drug?
Yes. See my “before and after steroids” answer. In it there is a picture of a book called the “gold s gym book of bodybuilding.” There is a man rowing a dumbell in one of the collage of pictures on the cover. He was diabetic and paved the way for others to look at insulin more closely as they noted what a crazy physique he developed. He manipulated his insulin dosages to achieve a synergistic effect on his muscle growth while staying lean. It resembles a mini version of today's crop of polypharmetic body augmentors. Pictured : Tim Belknap, type 2 diabetic. Manipulated his insulin and AAS to create a super dense and muscular build. Even at his short stature he overpowered those he competed against. Cf-2017 Continue reading >>
Why Have We Been So Unsuccessful In Developing Better Drug Delivery Mechanisms For Insulin?
Insulin is a hormone that works in the blood. It is a short protein which works to bring sugar out of the blood and into cells, amongst many other things. Because it's a protein, oral administration is difficult as it might be digested by enzymes called protease which break down protein into its building blocks - amino acids. This makes it lose its function as insulin. Moving a protein from the gastrointestinal tract into the blood, without it being broken down, is challenging. There might be some proteins which are resistant to proteases, but the need for it to act like insulin while being resistant is a venn diagram which to date has no overlap. That's why insulin is currently administered either as Subcutaneous (into fat) or Intravenous (into veins; but that happens mostly in emergencies). Addendum: I've just been to a few lectures since when I typed this out, so I have a few new fun treats to add! A further development would be the development of the artificial pancreas - which could be an implantable biological device that produces insulin and regulates its release just like a normal human pancreas would. This would change the lives of many a Type 1 diabetic. Currently, alternatives to Insulin administration include Pancreatic Transplantation, which is when a pancreas from a deceased donor is transplanted into a diabetic patient (or even patients who become diabetic following pancreas removal, due to cancer or pancreatitis amongst other reasons). The problems associated with this is that pancreas transplantation is major surgery, and the need for immunosuppression. Also, ideal donor organ availability remains an issue. An alternative is Pancreatic Stem Cell transplantation, where the insulin producing cells of the pancreas can be injected into the liver, where they Continue reading >>
Insulin Injection
Insulin injection is used to control blood sugar in people who have type 1 diabetes (condition in which the body does not make insulin and therefore cannot control the amount of sugar in the blood) or in people who have type 2 diabetes (condition in which the blood sugar is too high because the body does not produce or use insulin normally) that cannot be controlled with oral medications alone. Insulin injection is in a class of medications called hormones. Insulin injection is used to take the place of insulin that is normally produced by the body. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar. All of the types of insulin that are available work in this way. The types of insulin differ only in how quickly they begin to work and how long they continue to control blood sugar. Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes. Insulin comes as a solution (liquid) and a suspension (liquid with particles that will settle on standing) to be injected subcutaneousl Continue reading >>
In Mass Production Of Insulin, Antibiotic Resistance Strain Is Added To E.coli With The Insulin Gene. Is There A Risk That The Resistance Gene Would Be Passed To Other Bacteria, Resulting In Drug-resistant Disease Causing Bacteria?
It is a common practice to use an antibiotic resistance marker to select recombinantly expressed proteins. The resistance marker under consideration is typically coded in an extragenomic DNA vector called a plasmid. Plasmids are easy to transfer from parent to offspring. However horizontal transfer across different species is going to be more difficult because of many reasons. First the origin of replication that is essential to make copies of the plasmid via DNA replication is specific to the strain of E coli used. Other organisms will not be able to propagate this plasmid using this origin of replication. Secondly, maintaining this extragenomic plasmid in the cell comes at a great energetic penalty to the cell. So the bacteria do not retain this for many generations once the selective pressure of the antibiotic is removed. Third, for the plasmid to go across the physical barrier of the bacterial cell membrane and further into the target organism across its cell membrane is going to be a very improbable event. Biochemists jump through hoops (not really, but it is an involved process) to make this happen. For such a resistance gene to get successfully propagated in the target organism, it has to integrate with its genome, again this is a process that does not happen easily. It is more probable to find a pathogenic organism that is naturally resistant to your antibiotic (can be found by screening) than from such horizontal transfer processes. Also it needs to be added scientists did not "create" this antibiotic resistance gene. The found it probably in some natural source and used it to their advantage in the process. Continue reading >>
Insulin
What are Insulin Insulin is a hormone that occurs naturally in the body and can also be given by injection as a treatment for diabetes. Naturally-occurring insulin is made by the beta cells of the Islets of Langerhans located in the pancreas. It helps the cells of the body to uptake glucose (sugar) found in the carbohydrates we eat so that it can be used as energy or stored for later use. Insulin also controls glucose release from the liver. One of the main roles of insulin is to keep blood glucose levels from going too high (hyperglycemia) or too low (hypoglycemia). People with type 1 diabetes do not make enough insulin to satisfy their body's needs or make none at all. Insulin given by injection acts similarly to naturally occurring insulin. There are more than 20 different types of insulin available for diabetes treatment in the United States. The various types of insulin differ in several ways: such as source (animal, human or genetically engineered), the time for insulin to take effect and the length of time the insulin remains working (ie, rapid acting, short acting, intermediate acting, long acting or very long acting). Insulin is used to treat Type 1 diabetes and it may be used together with oral medications in the later stages of Type 2 diabetes. List of Insulin: Filter by: -- all conditions -- Drug Name View by: Brand | Generic Reviews Avg. Ratings Humulin R (Pro, More...) generic name: insulin regular 0 reviews 10 NovoLog Mix 70 / 30 FlexPen (More...) generic name: insulin aspart/insulin aspart protamine 0 reviews 10 Humalog Mix 75 / 25 (More...) generic name: insulin lispro/insulin lispro protamine 2 reviews 9.5 NovoLog Mix 70 / 30 (More...) generic name: insulin aspart/insulin aspart protamine 3 reviews 9.5 ReliOn / Novolin 70 / 30 (More...) generic name: i Continue reading >>
Which Has Less Side Effects For A Type 2 Diabetes Patient: Taking Insulin Or Taking Blood Sugar-lowering Drugs?
Thanks for the A2A. As a general rule OHAs (Oral hypoglycemic agents) are prescribed for Type 2 diabetes. Insulin is prescribed only when the blood sugar levels can't be maintained by OHAs alone / when there is a complication / when the patient cannot take Oral drugs for any reason. Now these are broad headings, which encompass a large number of clinical scenarios. Side effect profile of these drugs is an entire chapter in itself. The decision to use either is made after careful consideration of potential adverse effects and you'd be better off listening to your doctor who is familiar with the patient profile. There is no definite answer to your question, it is a subjective assessment. The main side effects of insulin are hypoglycaemia and weight gain. The major side effects of oral sugar-lowering drugs include hypoglycaemia, weight gain and fluid retention. They may also cause liver complications, urinary infections, and decreased absorption of Vitamin B12. If oral drugs are enough to maintain normal blood sugar levels, insulin treatment need not be started prematurely. However, if sugar levels are not under control, short term use of insulin is advised to prevent the onset of diabetic complications. In case the patient stops responding to oral drugs, then long term use of insulin is indicated. Editorial Team, 1mg It is very difficult to state with the given information if Insulin or blood sugar lowering drugs is having lesser side effects. Any treatment’s effects depend on various factors like age of patient, history of T2D and chronicity of disease. But usually doctors suggest , Combination drugs for patients with increased insulin resistance. Insulin + Drugs : where the function of the pancreas is severely limited. A healthier life style will reduce prescription t Continue reading >>
Insulin
Tweet Inside the pancreas, beta cells make the hormone insulin. With each meal, beta cells release insulin to help the body use or store the glucose it gets from food. Insulin is prescribed to people with type 1 diabetes. This is because type 1 diabetes destroys beta cells in the pancreas, meaning that the body can no longer produce insulin. People with type 2 diabetes make insulin, but their bodies don’t respond well to it. Some people with type 2 diabetes may take pills or insulin shots to help their bodies use glucose for energy. What you should know about insulin This section covers everything to do with insulin - insulin types, prescription, delivery, side effects, insulin pumps, over-dosage, lancets and more. Explore key guides in this section, including: How many types of insulin are there? There are 4 types of insulin, based on how soon the insulin starts working (onset), when it works the hardest (peak time) and how long it lasts in your body (duration). However, each person responds to insulin in his or her own way. That is why onset, peak time, and duration are given as ranges. The types of insulin are: Rapid-acting insulin (Lispro) reaches the blood within 15 minutes after injection. It peaks 30 to 90 minutes later and may last as long as 5 hours. Short-acting (regular) insulin usually reaches the blood within 30 minutes after injection. It peaks 2 to 4 hours later and stays in the blood for about 4 to 8 hours. Intermediate acting (NPH and lente) insulins reach the blood 2 to 6 hours after injection. They peak 4 to 14 hours later and stay in the blood for about 14 to 20 hours. Long acting (ultralente) insulin takes 6 to 14 hours to start working. It has no peak or a very small peak 10 to 16 hours after injection. It stays in the blood between 20 and 24 hou Continue reading >>
What Are The Possible Side Effects Of Insulin Lispro (humalog, Humalog Cartridge, Humalog Kwikpen, Humalog Pen)?
HUMALOG (insulin lispro) Injection DESCRIPTION HUMALOG® (insulin lispro injection) is a rapid-acting human insulin analog used to lower blood glucose. Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Insulin lispro differs from human insulin in that the amino acid proline at position B28 is replaced by lysine and the lysine in position B29 is replaced by proline. Chemically, it is Lys(B28), Pro(B29) human insulin analog and has the empirical formula C257H383N65O77S6 and a molecular weight of 5808, both identical to that of human insulin. HUMALOG has the following primary structure: HUMALOG is a sterile, aqueous, clear, and colorless solution. Each milliliter of HUMALOG U-100 contains insulin lispro 100 units, 16 mg glycerin, 1.88 mg dibasic sodium phosphate, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.0197 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. Each milliliter of HUMALOG U-200 contains insulin lispro 200 units, 16 mg glycerin, 5 mg tromethamine, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.046 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. font size A A A 1 2 3 4 5 Next What is Type 2 Diabetes? The most common form of diabetes is type 2 diabetes, formerly called non-insulin dependent diabetes mellitus or "adult onset" diabetes, so-called because it typically develops in adults over age 35, though it can develop at any age. Type 2 diabetes i Continue reading >>
Lantus (insulin Glargine) Side Effects
What Is Lantus (Insulin Glargine)? Lantus is the brand name of insulin glargine, a long-acting insulin used to treat adults and children with type 1 diabetes mellitus and adults with type 2 diabetes mellitus to control high blood sugar. Lantus replaces the insulin that your body no longer produces. Insulin is a natural substance that allows your body to convert dietary sugar into energy and helps store energy for later use. In type 2 diabetes mellitus, your body does not produce enough insulin, or the insulin produced is not used properly, causing a rise in blood sugar. Like other types of insulin, Lantus is used to normalize blood sugar levels. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual dysfunction. Proper control of diabetes has also been shown to reduce your risk of a heart attack or stroke. Lantus is meant to be used alongside a proper diet and exercise program recommended by your doctor. Lantus is manufactured by Sanofi-Aventis. It was approved for use by the Food and Drug Administration (FDA) in 2000 as the first long-acting human insulin administered once a day with a 24-hour sugar-lowering effect. Lantus Warnings You will be taught how to properly inject this medication since that is the only way to use it. Do not inject cold insulin because this can be painful. Always wash your hands before measuring and injecting insulin. Lantus is always clear and colorless; look for cloudy solution or clumps in the container before injecting it. Do not use Lantus to treat diabetic ketoacidosis. A short-acting insulin is used to treat this condition. It is recommended that you take a diabetes education program to learn more about diabetes and how to manage it. Other medical problems may affect the use of this Continue reading >>
Insulin Usually Better Than Oral Drugs For Type 2 Diabetes
According to a study published in , the combination of insulin and metformin may not benefit individuals with type 2 diabetes. Although the combination results in less weight gain, improved blood glucose control and less need for insulin, the researchers state that further research is required in order to provide solid evidence regarding the benefits and harms, as well as the risks of premature death. The study was conducted by researchers from the Copenhagen Trial Unit, Steno Hospital and the Copenhagen University Hospital. At present, guidelines recommend metformin, an oral blood glucose reducing medication, for type 2 diabetics starting insulin treatment. The researchers examined 2,217 individuals aged 18+ with type 2 diabetes. Among the trials examined, the team found insufficient reports of important patient outcomes, such as total mortality and death from heart disease. According to 20 trials, levels of HbA1c (a measure of average blood glucose levels over time) were reduced when insulin and metformin was taken together. Furthermore, the researchers found that the combination of drugs considerably reduced weight gain and body mass index (BMI) by an average of 1.6 kg. The researchers state that additional studies are required in order to research the long term benefits and harms of the combination, as it increases the risk of severe hypoglycaemic attack. In this week's BMJ podcast, Trish Groves, the deputy editor of BMJ, talks to lead author Bianca Hemmingsen about how this study was able to draw on more data than prior studies, and how the researchers examined major complications and mortality instead of surrogate outcomes, such as blood sugar levels and weight. In addition, Dr. Hemmingsen highlights the insufficient evidence for determining if the combination or Continue reading >>
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Insulin (medication)
"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[7] The wholesale cost in the developing world is about US$2.39 to $10.61 per 1,000 iu of regular insulin and $2.23 to $10.35 per 1,000 iu of NPH insulin.[8][9] In the United Kingdom 1,000 iu of regular or NPH insulin costs the NHS 7.48 pounds, while this amount of insulin glargine costs 30.68 pounds.[5] Medical uses[edit] Giving insulin with an insulin pen. Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacid Continue reading >>
