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Is Humulin Supposed To Be Cloudy?

Insulins - Brand Names

Insulins - Brand Names

Sort Which types of insulin are clear? Which types are cloudy? Three CLEAR (1) rapid-acting (2) short-acting (3) long-acting Three CLOUDY (1) intermediate-acting (2) human mixture (3) analog mixture Which insulin mixtures include insulin analogs? Are they cloudy or clear? (1) insulin lispro protamine 75% / insulin lispro (Humalog Mix 75/25) (2) insulin lispro protamine 50% / insulin lispro 50% (Humalog 50/50) (3) insulin aspart protamine 70% / insulin aspart 30% (NovoLog Mix 70/30) CLOUDY Continue reading >>

Humalog Kwikpens

Humalog Kwikpens

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet is designed to provide you with answers to some common questions about these medicines. It does not contain all the available information and does not take the place of talking with your doctor. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMALOG and its use that you should be aware of. All medicines have risks and benefits. Your doctor has more information about these medicines than is contained in this leaflet. Also, your doctor has had the benefit of taking a full and detailed history from you and is in the best position to make an expert judgement to meet your individual needs. If you have any concerns about using these medicines, talk to your doctor or pharmacist. What the HUMALOG insulins are used for HUMALOG insulins are used to reduce high blood sugar (glucose) levels in insulin dependent diabetic patients. Diabetes is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. Type 1 diabetes - also called Insulin Dependent Diabetes Mellitus (IDDM). Patients with type 1 diabetes always need insulin to control their blood sugar levels. Type 2 diabetes - also called Non insulin dependent diabetes mellitus (NIDDM). Some patients with type 2 diabetes may also need insulin after initial treatment with diet, exercise an Continue reading >>

Humulin N

Humulin N

Generic Name: insulin human Dosage Form: injection, suspension Indications and Usage for Humulin N HUMULIN N is an intermediate-acting recombinant human insulin indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus. Humulin N Dosage and Administration Important Administration Instructions Inspect HUMULIN N visually before use. It should not contain particulate matter and should appear uniformly cloudy after mixing. Do not use HUMULIN N if particulate matter is seen. Route of Administration HUMULIN N should only be administered subcutaneously. Administer in the subcutaneous tissue of the abdominal wall, thigh, upper arm, or buttocks. To reduce the risk of lipodystrophy, rotate the injection site within the same region from one injection to the next [see Adverse Reactions (6)]. Do not administer HUMULIN N intravenously or intramuscularly and do not use HUMULIN N in an insulin infusion pump. Dosage Information Individualize and adjust the dosage of HUMULIN N based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal. Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function or during acute illness [see Warnings and Precautions (5.2, 5.3), and Use in Specific Populations (8.6, 8.7)]. Dosage Adjustment due to Drug Interactions Dosage adjustment may be needed when HUMULIN N is coadministered with certain drugs [see Drug Interactions (7)]. Dosage adjustment may be needed when switching from another insulin to HUMULIN N [see Warnings and Precautions (5.2)]. Instructions for Mixing with Other Insulins HUMULIN N may be used with a prandial insulin if indicated. HUMULIN N m Continue reading >>

Humulin N

Humulin N

HUMULIN® N (human insulin [rDNA origin]) isophane) Suspension DESCRIPTION HUMULIN N (human insulin [rDNA origin] isophane) suspension is a human insulin suspension. Human insulin is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. HUMULIN N is a suspension of crystals produced from combining human insulin and protamine sulfate under appropriate conditions for crystal formation. The amino acid sequence of HUMULIN N is identical to human insulin and has the empirical formula C257H383N65O77S6 with a molecular weight of 5808. HUMULIN N is a sterile white suspension. Each milliliter of HUMULIN N contains 100 units of insulin human, 0.35 mg of protamine sulfate, 16 mg of glycerin, 3.78 mg of dibasic sodium phosphate, 1.6 mg of metacresol, 0.65 mg of phenol, zinc oxide content adjusted to provide 0.025 mg zinc ion, and Water for Injection. The pH is 7.0 to 7.5. Sodium hydroxide and/or hydrochloric acid may be added during manufacture to adjust the pH. Continue reading >>

Insulin In The Uk

Insulin In The Uk

Tweet Insulin may be a key part of your treatment if you suffer from diabetes. Insulin enables your body to use glucose. Different types of insulin can act very differently in different people. Insulin regime suitable for individual patients are tailored by your diabetes care team. Type or dosage of insulin can be changed if required to meet the individual needs of the patient. Insulin can be packaged in vials (bottles), cartridges or prefilled pens. The vials are used with syringes, whereas the cartridges are used with pen injectors. Prefilled pens are disposable pen injectors, which contain insulin. Prefilled pens are useful for people with dexterity or visual problems. List of insulins The table highlights the various insulin types, their manufacturers, the insulin source and how it's available. It also highlights insulin ranges that have been discontinued. Insulin type Name Manufacturer Type Source Rapid-acting analogue Apidra Sanofi analogue vial & cartridge Apidra Sanofi analogue prefilled pen Humalog Lilly analogue vial & cartridge Humalog Lilly analogue prefilled pen Novorapid Novo Nordisk analogue vial Novorapid Penfill Novo Nordisk analogue cartridge Novorapid Novolet Novo Nordisk analogue prefilled pen Long-acting analogue Lantus Sanofi analogue vial, cartridge & prefilled pen Levemir Novo Nordisk analogue cartridge & prefilled pen Tresiba Novo Nordisk analogue cartridge & prefilled pen Short-acting Human Actrapid Novo Nordisk human vial Actrapid Pen* Novo Nordisk human prefilled pen Actrapid Penfill* Novo Nordisk human cartridge Human Velosulin* Novo Nordisk human vial Pork Actrapid* Novo Nordisk pork vial Humaject S* Lilly human prefilled pen Humulin S Lilly human vial & cartridge Hypurin Bovine Neutral CP Pharmaceuticals beef vial & cartridge Hypurin Porci Continue reading >>

Insulin Use Tips

Insulin Use Tips

Before each use, take a moment to inspect the insulin prior to drawing it into the syringe; clear insulins should appear not discolored and clear; suspended insulins should be uniform in their cloudiness. [1][2] Do not use the insulin if: The bottle looks frosted. [3][4][5][6][7][8] Clear insulin that looks discolored or has turned cloudy, contains particles or haze. [9] Cloudy insulin that appears yellowish or remains lumpy or clotted after mixing. [10][8] See Insulin problems for more information about "bad" insulin. Damaged Insulin: Insulin that is getting too old, or has been dropped or shaken or mishandled, or exposed to a lot of light or heat, will be less effective than before. Freezing [11] destroys the molecules of ANY insulin; any that has either been frozen or is suspected of having been frozen should not be used. Insulin which has been frozen will not be able to do an effective job of controlling blood glucose. [12] Check for discoloration or floating objects in the insulin -- it may also be contaminated. It's also possible that the new or newer vial from the pharmacy may be flawed. If you've recently started it and are having problems, this might be the case. Taking down the lot number and getting a new vial that has a different batch/lot number should take care of this. Frosted insulin: If insulin is subjected to temperature extremes, such as freezing or overheating, the insulin can precipitate [13] on the vial's walls, giving it a frosty or frosted appearance.[5] Another term used to describe this is flocculation. [7][14] In the photo above, the insulin vial on the right is a visual example of what a frosted vial would look like. You can see the precipitated insulin clinging to the sides of it. The problem seems to be a particular one with R-DNA/GE/GM NPH Continue reading >>

Types Of Insulin - Topic Overview

Types Of Insulin - Topic Overview

Insulin is used to treat people who have diabetes. Each type of insulin acts over a specific amount of time. The amount of time can be affected by exercise, diet, illness, some medicines, stress, the dose, how you take it, or where you inject it. Insulin strength is usually U-100 (or 100 units of insulin in one milliliter of fluid). Short-acting (regular) insulin is also available in U-500. This is five times more concentrated than U-100 regular insulin. Long-acting insulin (glargine) is also available in U-300. This is three times more concentrated than U-100 long-acting insulin. Be sure to check the concentration of your insulin so you take the right amount. Insulin is made by different companies. Make sure you use the same type of insulin consistently. Types of insulin Type Examples Appearance When it starts to work (onset) The time of greatest effect (peak) How long it lasts (duration) Rapid-acting Apidra (insulin glulisine) Clear 5-15 minutes 30-60 minutes 3-5 hours Humalog (insulin lispro) Clear 5-15 minutes 30-90 minutes 3-5 hours NovoLog (insulin aspart) Clear 5-15 minutes 40-50 minutes 3-5 hours Afrezza (insulin human, inhaled) Contained in a cartridge 10-15 minutes 30-90 minutes 2½-3 hours Short-acting Humulin R, Novolin R (insulin regular) Clear 30 minutes 1½-2 hours 6-8 hours Intermediate-acting Humulin N, Novolin N (insulin NPH) Cloudy 1-4 hours 4-12 hours 14-24 hours Long-acting Lantus (insulin glargine) Clear 1-2 hours Minimal peak Up to 24 hours Levemir (insulin detemir) Clear 2 hours Minimal peak Up to 24 hours Rapid-acting insulins work over a narrow, more predictable range of time. Because they work quickly, they are used most often at the start of a meal. Rapid-acting insulin acts most like insulin that is produced by the human pancreas. It quickly Continue reading >>

Humulin N, 100 Units

Humulin N, 100 Units

INFORMATION FOR THE PATIENT WARNINGS THIS LILLY HUMAN INSULIN PRODUCT DIFFERS FROM ANIMAL-SOURCE INSULINS BECAUSE IT IS STRUCTURALLY IDENTICAL TO THE INSULIN PRODUCED BY YOUR BODY'S PANCREAS AND BECAUSE OF ITS UNIQUE MANUFACTURING PROCESS. ANY CHANGE OF INSULIN SHOULD BE MADE CAUTIOUSLY AND ONLY UNDER MEDICAL SUPERVISION. CHANGES IN STRENGTH, MANUFACTURER, TYPE (E.G., REGULAR, NPH, LENTE), SPECIES (BEEF, PORK, BEEF-PORK, HUMAN), OR METHOD OF MANUFACTURE (rDNA VERSUS ANIMAL-SOURCE INSULIN) MAY RESULT IN THE NEED FOR A CHANGE IN DOSAGE. SOME PATIENTS TAKING HUMULIN (HUMAN INSULIN, rDNA ORIGIN) MAY REQUIRE A CHANGE IN DOSAGE FROM THAT USED WITH ANIMAL-SOURCE INSULINS. IF AN ADJUSTMENT IS NEEDED, IT MAY OCCUR WITH THE FIRST DOSE OR DURING THE FIRST SEVERAL WEEKS OR MONTHS. DIABETES Insulin is a hormone produced by the pancreas, a large gland that lies near the stomach. This hormone is necessary for the body's correct use of food, especially sugar. Diabetes occurs when the pancreas does not make enough insulin to meet your body's needs. To control your diabetes, your doctor has prescribed injections of insulin products to keep your blood glucose at a near-normal level. You have been instructed to test your blood and/or your urine regularly for glucose. Studies have shown that some chronic complications of diabetes such as eye disease, kidney disease, and nerve disease can be significantly reduced if the blood sugar is maintained as close to normal as possible. The American Diabetes Association recommends that if your premeal glucose levels are consistently above 140 mg/dL or your hemoglobin A 1c (HbA 1c ) is more than 8%, consult your doctor. A change in your diabetes therapy may be needed. If your blood tests consistently show below-normal glucose levels you should also let Continue reading >>

What Is Humulin 70/30 Kwikpen?

What Is Humulin 70/30 Kwikpen?

Before you receive DARZALEX®, tell your healthcare provider about all of your medical conditions, including if you: have a history of breathing problems have had shingles (herpes zoster) are pregnant or plan to become pregnant. DARZALEX® may harm your unborn baby. Females who are able to become pregnant should use an effective method of birth control during treatment and for at least 3 months after your final dose of DARZALEX®. Talk to your healthcare provider about birth control methods that you can use during this time. are breastfeeding or plan to breastfeed. It is not known if DARZALEX® passes into your breast milk. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DARZALEX® may be given alone or together with other medicines used to treat multiple myeloma. Your healthcare provider will decide the time between doses as well as how many treatments you will receive. Your healthcare provider will give you medicines before each dose of DARZALEX® and on the first day after each dose of DARZALEX® to help reduce the risk of infusion reactions. If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment. Infusion reactions. Infusion reactions are common with DARZALEX® and can be severe. Your healthcare provider may temporarily stop your infusion or completely stop treatment with DARZALEX® if you have infusion reactions. Tell your healthcare provider right away if you get any of the following symptoms: shortness of breath or trouble breathing dizziness or lightheadedness (hypotension) cough wheezing throat tightness runny or stuffy nose headache itching nausea vomiting chills fever Changes in blood tests. DARZALEX Continue reading >>

Humulin-n

Humulin-n

How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. NPH is an intermediate-acting insulin. It takes 1 to 3 hours to begin working after injection, reaches its maximum effect between 5 and 8 hours, and stops working after about 18 to 24 hours. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. What form(s) does this medication come in? Vial Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. May contain dimethicone, hydrochloric acid, and sodium hydroxide. Cartridge/KwikPen Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, Continue reading >>

Humulin 30/70 (vial) Suspension For Injection

Humulin 30/70 (vial) Suspension For Injection

Brand Information Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Humulin 30/70 (Vial) Suspension for injection. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes mellitus is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets Continue reading >>

Intermediate-acting Insulins

Intermediate-acting Insulins

Rapid-Acting Analogues Short-Acting Insulins Intermediate-Acting Insulins Long-Acting Insulins Combination Insulins Onset: 1- 2 hours Peak: 4-12 hours Duration: 14 - 24 hours (up to 24 hours) Solution: Cloudy Comments: Human Insulin Isophane Suspension. Cloudy/ milky suspension of human insulin with protamine and zinc. Mixing NPH + Aspart (Novolog ®): Compatible - NovoLog should be drawn into the syringe first. The injection should be made immediately after mixing. NPH + Lispro (Humalog ®): Compatible - Humalog should be drawn into the syringe first. The injection should be made immediately after mixing. NPH +Regular insulin: Always draw the Regular (clear) insulin into the syringe first. Phosphate-buffered insulins ( NPH insulin) should NOT be mixed with lente insulins. Zinc phosphate may precipitate, and the longer-acting insulin will convert to a short-acting insulin to an unpredictable extent. Currently available NPH and short-acting insulin formulations when mixed may be used immediately or stored for future use. NPH HUMAN INSULIN Description Humulin N [Human insulin (rDNA origin) isophane suspension] is a crystalline suspension of human insulin with protamine and zinc providing an intermediate-acting insulin with a slower onset of action and a longer duration of activity (up to 24 hours) than that of Regular human insulin. The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual. As with all insulin preparations, the duration of action of Humulin N is dependent on dose, site of injection, blood supply, temperature, and physical activity. Humulin N is a sterile suspension and is for subcutaneous injection only. It should not be used intravenously or intramuscularly. The concentration of H Continue reading >>

N Human Insulin Isophane Suspension (recombinant Dna Origin) 100 Units/ml

N Human Insulin Isophane Suspension (recombinant Dna Origin) 100 Units/ml

NOVOLIN N - insulin human injection, suspension Novo Nordisk ---------- NOVOLIN® PATIENT PACKAGE INSERT Patient Information for Novolin® N NOVOLIN® N (NO-voe-lin) NPH, Human Insulin Isophane Suspension Injection (recombinant DNA origin) 100 units/mL Important: Know your insulin. Do not change the type of insulin you use unless told to do so by your healthcare provider. The amount of insulin you take as well as the best time for you to take your insulin may need to change if you take a different type of insulin. Make sure that you know the type and strength of insulin that is prescribed for you. Read the Patient Information leaflet that comes with Novolin N before you start taking it and each time you get a refill. There may be new information. This leaflet does not take the place of talking with your healthcare provider about your diabetes or your treatment. Make sure you know how to manage your diabetes. Ask your healthcare provider if you have any questions about managing your diabetes. What is Novolin N? Novolin N is a man-made insulin (recombinant DNA origin) NPH, Human Insulin Isophane Suspension that is structurally identical to the insulin produced by the human pancreas that is used to control high blood sugar in patients with diabetes mellitus. Who should not use Novolin N? Do not take Novolin N if: Your blood sugar is too low (hypoglycemia). You are allergic to anything in Novolin N. See the end of this leaflet for a complete list of ingredients in Novolin N. Check with your healthcare provider if you are not sure. Tell your healthcare provider: about all of your medical conditions. Medical conditions can affect your insulin needs and your dose of Novolin N. if you are pregnant or breastfeeding. You and your healthcare provider should talk about the best way Continue reading >>

Humulin-n

Humulin-n

How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. NPH is an intermediate-acting insulin. It takes 1 to 3 hours to begin working after injection, reaches its maximum effect between 5 and 8 hours, and stops working after about 18 to 24 hours. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. What form(s) does this medication come in? Vial Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. May contain dimethicone, hydrochloric acid, and sodium hydroxide. Cartridge/KwikPen Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, Continue reading >>

Humulin Nph (vial) Suspension For Injection

Humulin Nph (vial) Suspension For Injection

Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Humulin NPH (Vial) Suspension for injection. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes mellitus is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets. HUMULIN is identic Continue reading >>

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