diabetestalk.net

Insulin Mimicking Supplements

  1. Insulin
  2. Insulin Mimicking Supplements
Study Shows Herbal Extracts Can Mimic Insulin’s Effects

Study Shows Herbal Extracts Can Mimic Insulin’s Effects

Natural Health News — Substances found in the herbs purslane and tindora appear to reduce blood sugar levels, according to a new research. The possibility of using herbal extracts to treat metabolic conditions is receiving more and more research interest. Alternatives to conventional drugs used in the treatment of type-2 diabetes are needed because these drugs can cause adverse effects like fat accumulation and liver problems. In general the herbs with the most potential include plants with a high concentration of polyphenolic compounds, alkaloids or alpha lipoic acid. Bilberry (vaccinium myrtillus) for example, contains high levels of polyphenolic compounds. It is considered a potential anti-diabetic plant and has recently been shown to help reduce the risk of cardiovascular disease. There are also clinical studies that suggest that ginger (zingiber officinale) can reduce blood glucose levels in humans, while milk-thistle (silybum marianum) and jiaogulan (gynostemma pentaphyllum) – a creeping vine native to China, northern Vietnam, southern Korea, and Japan – has been shown to stimulate insulin secretion, inhibit gluconeogenesis, or reduce triglycerides and insulin resistance, the researchers at the University of Applied Sciences in Austria note. Insulin-like activity The leaves of the purslane plant are likewise rich in nutrients including omega-3 fatty acids (a-linolenic acid), vitamin A, C and some B-complex vitamins. With this in mind, the researchers looked at the two extracts taken from six different plants: purslane, tindora, ginger, bilberry, jiaogulan, and milk thistle as well as a mixture of different polyphenols. Of these, purslane (portulaca oleracea), found throughout the world, and tindora (coccinia grandis) – a native of Southeast Asia, also know Continue reading >>

Nutritional Supplements And Diabetes

Nutritional Supplements And Diabetes

This month, we feature a three-part series on diabetes to observe American Diabetes Month. This article reviews the role nutritional supplements play if you’ve already been diagnosed with diabetes. Because diabetes is a disease inherently tied to nutrition, nutrition is an important factor in managing diabetes. While it may not be replacement for traditional treatment in all cases, nutritional supplements provide key nutrients, antioxidants, minerals, and herbs that can help manage blood glucose levels, enhance insulin sensitivity, minimize neuropathy (nerve damage disorders) and provide cardiovascular support. To be supplement-smart, learn about the potential benefits of the following: Alpha Lipoic Acid (ALA) ALA is a powerful antioxidant that neutralizes free-radicals in nearly all areas of the cell. High blood glucose can cause free-radical buildup due to oxidative stress, resulting in nerve damage and other issues, but ALA can help combat this process. ALA has also been shown to improve insulin sensitivity, improve circulation, and may help muscle cells take up blood sugar. The recommended dosage level is 200-600 mg/day, but because it may affect glucose and minerals in the blood, levels should be monitored carefully. It is also used as a treatment for nerve regeneration against diabetic neuropathy in Germany. Bilberry A relative of the blueberry, its fruit and leaves provide powerful antioxidants called anthocyanidins which can help prevent damage to blood vessels, a cause of nerve pain. Anthocyanidins can also prevent damage to the retina and prevent and reduce the severity of diabetic cataracts. The potential for lowering blood glucose has also been demonstrated in animal studies. Biotin One of the B-vitamins, biotin works in conjunction with chromium to increa Continue reading >>

Supplements

Supplements

The Diabetes Control & Complications Trial established that diabetics won't get complications if the blood sugar is normal, but their six times elevated risk of heart disease remains. Hence, I take supplements to protect me from heart disease, as well as to protect my general health. If there should be any doubt about vitamin status, the truth can be determined with the Spectracell test which looks at how long white blood cells survive in growth medium low in one nutrient: If the cells die quickly, there can be no doubt of a deficiency in that nutrient. If taking supplements for a period of time doesn't improve the test result, I change the brand of supplement until the test show repletion. The antioxidants lessen free radical activity and so retards ageing. I think of them protecting my fat from rancidity (called "lipid peroxidation") and preventing damage to my DNA. Diabetics have more damaged DNA, which means they have inadequate antioxidant protection. Age spots mean excess free radical activity. Antioxidants help with heart disease because oxidized LDL cholesterol is closely correlated with heart disease, and because they normalize the excessive clotting tendency of diabetics' blood (better than aspirin) which lessens heart attacks. The antioxidants work as a team: vitamin C revitalizes vitamin E and the others, and is itself revitalized by a selenium-dependant enzyme, glutathione peroxidase. Vitamin A and its precursor, beta-carotene, protect the skin and mucous membranes. Vitamin C protects the watery parts like the blood serum, E protects the cell membranes, and so on. You can, however, have too much of a good thing - after all, without the oxidation of glucose, we'd have no way to power our metabolic processeses. Vitamin C: 2+ grams: the studies are crystal cle Continue reading >>

Can Glycolog Really Turn Carbs Into Muscle Fuel?

Can Glycolog Really Turn Carbs Into Muscle Fuel?

GlycoLog by Blackstone Labs is a product specifically designed to mimic Insulin and help transport the nutrients more effectively. Specifically, it will transport the carbs you eat to the muscles making them muscle fuel and allowing them to be put to good use. This is a special kind of supplement and certainly not something we see every day, but we decided to have a closer look and find out how effective the product actually is. See, loading up on empty carbs is usually not a great idea when trying to build a lean physique and lose pounds. But the thing is in some cases it can actually be a good thing. The insulin spikes you experience from eating carbs can be used to advantage and the carbs can be used to fuel your muscles instead of turning into fat. So without further ado, let's give Glycolog a closer look… What’s in Glycolog? Let's kick things off by having a look at some of the ingredients that make up this product: Cinnamon Bark Extract: This compound is meant to lower your Glucose levels and raise your insulin sensitivity. Bitter Melon: Increases the utilization of Glucose and reduces glycogenesis in the liver. Chromium: Scientifically shown to stabilize blood sugar levels and improve their utilization. Super Berberine: Has the ability to reduce Glucose levels and increase the Glucose uptake by muscle cells. At its simplest, it is designed to help improve how your body utilizes the sugars you ingest through your normal diet and prevent them from turning fat gainers and instead converting them into muscle builders. Here is the complete supplement label with all the ingredients on it: Benefits The main benefits that Blackstone Labs claims from the use of GlycoLog include: More carbs delivered to the muscles More muscle gains Better glucose utilization Increased Continue reading >>

Articles Written By Rehan Jalali

Articles Written By Rehan Jalali

Supplementation Articles The Power Of Insulin: Supplements to maximize insulin and blood sugar levels to increase lean muscle mass and reduce body fat Is Insulin good or bad? Many people talk about controlling blood sugar levels and hence insulin levels to prevent fat storage, reduce cravings, and sustain energy levels. Other diets have you cut out carbohydrates all together to minimize and control insulin levels. But can insulin really help you build more muscle mass? Will it just cause more fat storage and halt your fat loss goals? Insulin is a hormone that has been discussed heavily in the bodybuilding and health communities. It’s time to set the insulin record straight and find out more about this intriguing hormone and the supplements that can help you positively manipulate it. Let’s dive into the functionality of insulin including biochemistry (for all those non-techies, you can skip this detailed section) and see exactly how it works in the body and its metabolic consequences. Insulin is a peptide hormone that is released from the beta cells of the pancreas. It is released due to a rise in blood sugar levels in the body that is induced mainly by eating carbohydrates but to a lesser degree by some amino acids in protein sources. This hormone is primarily responsible for the direction of energy metabolism after eating. Insulin helps regulate blood sugar levels and helps keep them in the range of 75-120 mg/dl. Individuals with metabolic disorders such as type I and type II diabetes mellitus cannot endogenously produce insulin so insulin shots are necessary or they cannot use their insulin properly and may have insulin insensitivity. Insulin binds to specific receptors in cell membranes and helps drive glucose into the cell. Normally the cell membranes are imperm Continue reading >>

Diabetes Medication: Insulin-sensitizers & Insulin Mimetics

Diabetes Medication: Insulin-sensitizers & Insulin Mimetics

If diet and exercise are not adequate to bring your blood sugars under control, the next level of treatment to consider is oral blood sugar–lowering medication, commonly known as oral hypoglycemic agents (OHAs). There are three categories of OHAs, those that increase sensitivity to insulin, those whose action resembles that of insulin, and those that provoke your pancreas to produce more insulin. The first group is known as insulin sensitizers (or ISAs, for insulin-sensitizing agents); the second are the insulin mimetics (or IMAs, for insulin-mimetic agents), which act like insulin but do not build fat. Finally, there are the original OHAs, like sulfonylureas. I only recommend the insulin sensitizers and insulin mimetics, for reasons that will become plain in short order. (Some drug companies have combined the old OHAs with insulin sensitizers, a move I strongly challenge. Tell your doctor you do not want any product containing an agent that works by causing the pancreas to make more insulin. This includes the old sulfonylureas and the new, similar drugs called meglitinides.*) For people who still have sufficient insulin-producing capacity, insulin sensitizers alone may provide the extra help they need to reach their blood sugar target. Some insulin-resistant individuals who produce little or no insulin on their own may find a combination of insulin sensitizers and insulin mimetics useful in reducing their doses of injected insulin. *In addition to causing beta cell burnout, sulfonylureas also impair circulation in the heart and elsewhere by closing ATP-sensitive potassium channels that relax blood vessels. There are three ISAs currently on the market, and at this writing I prescribe all three of them—metformin (Glucophage), rosiglitazone (Avandia), and pioglitazone Continue reading >>

Alpha Lipoic Acid, Vanadyl Sulfate, And Chromium

Alpha Lipoic Acid, Vanadyl Sulfate, And Chromium

Insulin Mimickers and Insulin Sensitizers It used to be that you heard a lot about insulin and a few supplements that would make it work better. Unfortunately, the supplements that were recommended were not marketed as insulin sensitizers, but instead, anabolics. When people would purchase the supplements and failed to experience astounding muscle growth, they simply wrote it off as yet another worthless supplement. Sales soon dropped and supplement companies stopped marketing them all together. Then came the low carb craze. Now this same group of supplements popped their heads up and called themselves "carbohydrate managers". Once again the public is given slightly skewed information about what these compounds actually do. They are told that they will reduce the fattening affect of carbohydrates. After all, that is what the public wants to hear. Just as the bodybuilding public wanted to hear that they made you grow muscles. But if you think about it, there is nothing more fattening than insulin, and if you have a supplement that mimics the effects of insulin, you basically have a supplement that "helps" insulin make you fatter. Despite the picture that I have just painted, I am still a fan of "insulin agonists", specifically, alpha lipoic acid, vanadyl, and chromium. Lets take a look at what they actually do and why I think they are valuable to anybody trying to alter their body composition. The Science First of all, to understand how these supplements work you have to understand how insulin works. I am going to give you the "science" answer strait from the research without watering it down too much so hold onto your thinking cap? Insulin signaling regulates glucose uptake into fat and muscle cells through the recruitment of glucose transporters (GLUT 4) from an intrac Continue reading >>

5 Supplements For Insulin Control

5 Supplements For Insulin Control

Insulin is secreted from the pancreas whenever we eat any food that contains sugar—so basically that includes all carbohydrates. While most people only associate Insulin with sugar and weight gain, it also has an important role in building muscle. Insulin is considered one of the most anabolic, or muscle building, hormones in the body, so it is rather important when it comes to putting on any lean muscle. However, too much insulin will cause you to gain excess fat. HOW INSULIN WORKS After you eat, blood glucose rises and insulin is released to control blood glucose levels, ensuring a normal level is reached. Once insulin is released, it goes to work by clearing the blood of sugar and delivering it directly to the muscles to help reload glycogen. However, the muscles have a limited capacity for sugar or glucose storage. Once the muscles’ glycogen stores are full, glucose is shuttled directly to adipose or fat tissue for storage. NUTRIENT TIMING The key to managing your insulin is using strategic nutrient timing. You should eat the majority of your carbohydrates when your glycogen stores are most depleted, such as after a workout or first thing in the morning. Then, you should maintain healthy insulin and blood glucose levels the rest of day by eating low glycemic, fiber-rich carbohydrates such as whole grains, greens, nuts and even the occasional piece of fruit. In fact, the only time you should deliberately increase insulin levels is after a workout during the “anabolic window.” 5 SUPPLEMENTS With that being said, there are also a few supplements that you may want to consider to enhance blood sugar control and insulin levels throughout the day. Alpha Lipoic Acid: This potent antioxidant is considered an insulin mimicker, which means it mimics the action of insul Continue reading >>

Glucose Disposal - Winning The War With Carbs!

Glucose Disposal - Winning The War With Carbs!

Proper glucose disposal and utilization is one of the primary factors to superior muscle building, fat loss, and athletic performance. If you're one of the few blessed with incredible genetics that process carbs (glucose) in an efficient manner, building size and losing flab will come rather easily. However, the majority of us aren't genetic freaks and our nutrient partitioning and glucose disposal abilities are somewhere between mediocre and extremely poor. For us, adding muscle and losing fat take considerably more effort, but all is not lost. Related - Whey Protein's Impact on Blood Glucose Fortunately, researchers have identified several all natural compounds that improve the body's absorption, utilization, and disposal of glucose. These are aptly titled glucose disposal agents. Don't worry if you're not familiar with the term or even how they work because we've got all the info ahead in easy to understand terms. Up Close With Carbs To understand how glucose disposal agents (GDAs) work, we first must gain an understanding of what happens when we consume carbohydrates. Most carbs are composed of large chains of sugar molecules, known as monosaccharides. When several monosaccharides (simple sugars) are linked together, they form a polysaccharide, or complex carbohydrate. Your body must break down these longer chains into smaller ones before they can be absorbed into the bloodstream and utilized by the body. Carb digestion begins in the mouth where amylase (a salivary enzyme) breaks down starch (a complex sugar found in plant foods) into smaller molecules. Carbs then enter the stomach and pass right on through to the small intestine, where other enzymes convert these smaller, simple sugars into glucose and fructose. These are the two sugars that enter the bloodstream a Continue reading >>

Protocatechuic Acid Activates Key Components Of Insulin Signaling Pathway Mimicking Insulin Activity.

Protocatechuic Acid Activates Key Components Of Insulin Signaling Pathway Mimicking Insulin Activity.

Abstract SCOPE: Insulin resistance represents an independent risk factor for metabolic and cardiovascular diseases. Researchers have been interested in identifying active harmless compounds, as many insulin-sensitizing drugs have shown unwanted side-effects. It has been demonstrated that anthocyanins and one of their representative metabolites, protocatechuic acid (PCA), ameliorate hyperglycemia, and insulin sensitivity. This study investigated the mechanism of action of PCA responsible for the glucose uptake upregulation. METHODS AND RESULTS: In human visceral adipocytes, PCA stimulated insulin receptor substrate-1 (IRS-1) tyrosine phosphorylation (+40% with respect to untreated cells) and the downstream events, i.e. phosphoinositide 3-kinase binding to IRS-1 and Akt phosphorylation (+100%, +180%, respectively, with respect to untreated cells). The insulin-like activity of PCA seemed to be mediated by insulin receptor since by inhibiting its autophosphorylation, the PCA effects were completely abolished. Furthermore, PCA was able to activate adenosine monophosphate-activated protein kinase, a serine/threonine kinase whose activation elicits insulin-sensitizing effects. CONCLUSION: This study showed that PCA stimulates the insulin signaling pathway in human adipocytes increasing GLUT4 translocation and glucose uptake. Decreasing insulin resistance is a most desirable aim to be reached for an effective therapeutic/preventive action against metabolic syndrome and type 2 diabetes. Identifying specific food/food components able to improve glucose metabolism can offer an attractive, novel, and economical strategy. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Continue reading >>

Only The Latest Insulin Research For Your Knowledge

Only The Latest Insulin Research For Your Knowledge

Only the Latest Insulin Research for your Knowledge fitFLEX Articles - Learn, Share and Discover google_ad_client="ca-pub-1779295655237148";google_ad_slot="5106849510";google_adsbygoogle_status="done";google_ad_width=930;google_ad_height=250;google_loader_features_used=256;google_responsive_auto_format=12;google_ad_modifications={"plle":true,"eids":["368226201","62710010","62710013","38893302","21061122","191880502"],"loeids":["368226211","38893312"]};google_loader_used="aa";google_reactive_tag_first=false;google_ad_format="930x250";google_ad_unit_key="4097502506";google_ad_dom_fingerprint="817738208";google_sailm=false;google_unique_id=2;google_async_iframe_id="aswift_1";google_start_time=1514671949792;google_pub_vars="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";google_bpp=2;google_async_rrc=0;google_iframe_start_time=new Dat Continue reading >>

Helpful Supplements For Diabetes

Helpful Supplements For Diabetes

There are only a handful of supplements promoted as being helpful for people with diabetes that actually work. You can read about the ones that don't and learn about the flawed research and fake online marketing with shills that is used to promote them HERE. Here we'll look at the few supplements that may be helpful. To be included on this page, the usefulness of a supplement must be supported by peer reviewed research not funded by someone with a financial stake in the supplement. In addition, the supplement should be recommended by people with diabetes with long-term reputations among the online community as objective sources--not shills for supplement companies who suddenly pop up claiming excellent results for some currently popular supplement. Vitamin D is Low in People Diagnosed with Diabetes But Supplementation Doesn't Help Evidence is accumulating that suggests that Vitamin D is low in people who develop Type 2 diabetes. Because of this there has been speculation that Vitamin D improves insulin sensitivity. Unfortunately, there is not a scintilla of evidence that supplementing with Vitamin D in any form will reverse diabetes. I am temporarily leaving Vitamin D in the "helpful" category, because it is possible it has some value in countering heart disease, but the evidence is accumulating that it may be just another overhyped simplistic cure promoted by unscrupulous celebrity doctors looking to earn fortunes selling products to people suffering serious chronic illnesses. The early enthusiasm for Vitamin D as a treatment for diabetes occurred after a November 2007 a study headed by Dr. Paul Knekt published in Diabetes Care found that over 17 years in a population of roughly 4,000 Finnish men and women, individuals with higher blood levels of vitamin D had a 40 per Continue reading >>

3 Of The Best Insulin Supplements For Weight Loss

3 Of The Best Insulin Supplements For Weight Loss

There is no denying that insulin issues and weight issues go together. When you eat foods that have carbohydrates, insulin is released to remove glucose. When insulin starts to not work as well, fat starts to deposit on the body and weight loss becomes a battle. Insulin supplements can help things get back on track and promote weight loss without having to cut out carbs. But, which supplements are the best supplements to take? Here is a look at 3 of the most popular insulin supplements that will help with weight loss: BioTrust’s IC-5 IC-5 from BioTrust contains known ingredients that help you combat insulin sensitivity issues. For instance, the cinnamon bark has been shown to increase glucose metabolism by up to 10 times. Moreover, it can help to manage blood sugar after a high-carb meal. Another ingredient is Berberine, which helps to increase the signal between insulin and the receptors it is associated with. It also increases glucose metabolism, and it promotes the muscle to use the glucose rather than the fat. Of course, reducing blood sugar levels can help with your insulin and weight loss efforts too, and the Pterocarpus Marsupium inside of BioTrust’s IC-5, has been shown to reduce blood sugar levels but 21% two hours after a meal. Also, a phytochemical from Fenugreek is included to increase the sensitivity of insulin receptors in the muscle tissue and increase glycogen storage, as well as decrease fat storage. And the last ingredient, R-ALA, is an acid that has been shown to increase insulin sensitivity by 25% in one month. It also helps to increase the number of glucose transporters to help get rid of the glucose from the blood stream. Combine all of these ingredients with BioTrust’s amazing customer service and money back guarantee, and you have one of th Continue reading >>

Ala: The Most Powerful Anti-oxidant Supplement

Ala: The Most Powerful Anti-oxidant Supplement

Do you know about the most powerful anti-oxidant in the world? You probably wouldn’t. It’s called Alpha Lipoic Acid aka ALA. It is one of the most powerful antioxidants present today and is widely used as a supplement in the world of bodybuilding, fat loss and general well-being. What is Alpha Lipoic Acid aka ALA? Alpha lipoic acid (ALA), also known as thioctic acid, is basically a fatty acid also found in the human body. It exists in the mitochondria of the cell and is involved in energy metabolism. Since it is an anti-oxidant its prime function is the prevention of free radical attack. Being both water and fat soluble, this unique trait of ALA allows it to cross the blood brain barrier and therefore, makes it the most preferable anti-oxidant by most fitness coaches and athletes in the world. Benefits Of ALA ALA is a very versatile antioxidant, capable of fighting against almost every free radical species. It is known to prevent various types of oxidations and inflammations that occur in the body which further prevents heart diseases, liver diseases, obesity, Alzheimer’s disease and a few other neurological issues. It is also known to oxidize nutrients from the food by converting simple sugars into energy. ALA And Insulin: Diabetes And Muscle Repair ALA has proven to a boon for diabetic patients because of its insulin mimicking traits which helps in enhancing the insulin sensitivity. It is capable of functioning in both extracellular and intracellular environments in the body. Lifters who train at a high intensity can boost muscle repair and recovery by supplementing with ALA. Food Sources ALA in food sources is almost negligible. However, organ meats such as liver and to a lesser extents spinach and broccoli contain small traces of ALA. Dosage There is no specif Continue reading >>

Cinnamon Mimics Insulin, But Does Not Increase Creatine Uptake

Cinnamon Mimics Insulin, But Does Not Increase Creatine Uptake

Cinnamon is a spice from the dried aromatic bark of the cinnamon tree. It is used as a spice for all sorts of cookery and is lately added to some bodybuilding supplements. Creatine monohydrate has without a doubt become one of the most popular nutritional supplements, and it is used to enhance athletic performance. Companies strive to develop formulations in order to maximize creatine absorption and may also provide a means to either partially bypass or up-regulate the function of creatine transporter-1. It has been observed that cinnamon extract (Cinnulin) mimics the effects of insulin, thereby up-regulating glucose uptake and insulin signaling. [1] It has been observed in the literature that Cinnamon extract (Cinnulin™) potentiates an insulin effect and successive insulin signaling through the up-regulation of glucose transport.[2] So, combining creatine monohydrate with Cinnamon extract (Cinnulin™) may increase muscle creatine uptake by stimulating skeletal muscle-mediated glucose uptake. A study in rats suggested that the cinnamon extract would improve insulin action via increasing glucose uptake, at least in part through enhancing the insulin-signaling pathway in skeletal muscle.[3] Cinnulin appears to act like insulin, which may up-regulate insulin signaling. A research done by Ryan D. Schoch [1] examined the effects of seven-week Cinnulin and Creatine monohydrate supplementation. Muscle strength and mass, body composition, muscle creatine uptake, serum insulin and IGF-1 were measured. Subjects were administered 20 g of Creatine monohydrate and Cinnamon extract (as Cinnulin) during the loading phase, and 5 g of creatine and 250 mg of Cinnulin per day during the maintenance phase. It has been concluded that Cinnulin combined with creatine monohydrate is no more Continue reading >>

More in insulin