Humulin 70/30 Dosage Chart

Novolin 70/30

Novolin 70/30 R/Neutral/NPH/Isophane Mix by Novo Nordisk intermediate-acting r-DNA/GE/GM U100 isophane Action in dogs: onset 0.5-3h, peak 2-10h, duration 4-24h Line: Novolin Also known as: Actraphane 30/70, Mixtard 30[1] Penmix 30,[2] Novolin 30R, ReliOn/Novolin 70/30 Similar to: Huminsulin Profil III, Humulin 3/7 Humulin 30/70, Humulina 30/70, Humuline 30/70, Humulin M3, Profil 30, Umuline Profil 30 Humulin 70/30, Humulin Mix 30/70 Humulin ReliOn 70/30 Insuman Comb 30, Winthrop Comb 30 Names of Lilly r-DNA/GE/GM insulins worldwide Use and Handling: Shelf Life: 24 months Type: cloudy When Opened: 6 weeks room temp. In Pen: 6 weeks room temp. Notes: Protect from light and heat Do Not Freeze, Resuspend Do not use if product does not re-suspend Do not use intravenously [3] This is the Novo Nordisk brand name for one of the mixed 30% R/neutral, 70% NPH/isophane crystal insulin it sells in North America; the other is ReliOn/Novolin 70/30. The same insulin made by the same company is called Mixtard 30 [4][5] and Actraphane 30/70 [6][7] once you cross the Atlantic. As of January 1, 2010, Novo has discontinued offering Novolin 70/30 in cartridges for refillable insulin pens. [12][13] Let's look at the differences in the two insulins. Lente is comprised of 70 % long-acting Ultralente insulin and 30% short-acting Semilente insulin. So proportions of a long-acting and short-acting insulin are being combined to produce a intermediate-acting insulin. Both Ultralente and Semilente insulin are suspended by adding zinc and the size of their respective insulin crystals. The largest insulin crystals are those of Ultralente, while Semilente contains the smallest, or microcrystals. Simply put, you're combining a long insulin and a short insulin to make an intermediate-acting one.[14] 70/30 Continue reading >>

Types Of Insulin For Diabetes Treatment

Many forms of insulin treat diabetes. They're grouped by how fast they start to work and how long their effects last. The types of insulin include: Rapid-acting Short-acting Intermediate-acting Long-acting Pre-mixed What Type of Insulin Is Best for My Diabetes? Your doctor will work with you to prescribe the type of insulin that's best for you and your diabetes. Making that choice will depend on many things, including: How you respond to insulin. (How long it takes the body to absorb it and how long it remains active varies from person to person.) Lifestyle choices. The type of food you eat, how much alcohol you drink, or how much exercise you get will all affect how your body uses insulin. Your willingness to give yourself multiple injections per day Your age Your goals for managing your blood sugar Afrezza, a rapid-acting inhaled insulin, is FDA-approved for use before meals for both type 1 and type 2 diabetes. The drug peaks in your blood in about 15-20 minutes and it clears your body in 2-3 hours. It must be used along with long-acting insulin in people with type 1 diabetes. The chart below lists the types of injectable insulin with details about onset (the length of time before insulin reaches the bloodstream and begins to lower blood sugar), peak (the time period when it best lowers blood sugar) and duration (how long insulin continues to work). These three things may vary. The final column offers some insight into the "coverage" provided by the different insulin types in relation to mealtime. Type of Insulin & Brand Names Onset Peak Duration Role in Blood Sugar Management Rapid-Acting Lispro (Humalog) 15-30 min. 30-90 min 3-5 hours Rapid-acting insulin covers insulin needs for meals eaten at the same time as the injection. This type of insulin is often used with Continue reading >>

Important Safety Information For Humulin R U-500

Humulin R U-500 is contraindicated during episodes of hypoglycemia and in patients hypersensitive to Humulin R U-500 or any of its excipients. Dosing Errors: Extreme caution must be observed in measuring the dose of Humulin R U-500 because inadvertent overdose may result in serious adverse reaction or life-threatening hypoglycemia. Hyperglycemia, Hypoglycemia or Death Due to Dosing Errors in the Vial Presentation: Medication errors associated with the Humulin R U-500 vial resulting in patients experiencing hyperglycemia, hypoglycemia or death have been reported. Instruct patients to always inspect insulin vials to confirm that the correct insulin is dispensed including the correct brand and concentration. For the Humulin R U-500 vial, particular attention should be paid to the 20-mL vial size, prominent “U-500” and warning statements on the vial label, and distinctive coloring on the vial and carton. Dosing errors have occurred when Humulin R U-500 was administered with syringes other than a U-500 insulin syringe. Patients should be prescribed U-500 syringes for use with Humulin R U-500 vials. The dose of Humulin R U-500 should always be expressed in units of insulin. Instruct patients to always check the insulin label before each injection. Use only a U-500 insulin syringe with Humulin R U-500 to avoid administration errors. Do not use any other type of syringe to administer Humulin R U-500. Adhere to administration instructions. Instruct the patient to inform hospital or emergency department staff of the dose of Humulin R U-500 prescribed. If using the Humulin R U-500 KwikPen, patients should be counseled to dial and dose the prescribed number of units of insulin (NO dose conversion is required). DO NOT transfer Humulin R U-500 from the Humulin R U-500 KwikPen int Continue reading >>

Combination Insulins

Rapid-Acting Analogues Short-Acting Insulins Intermediate-Acting Insulins Long-Acting Insulins Combination Insulins Novolin® 70/30 - Humulin® 70/30 Novolog® Mix 70/30 Humalog® Mix 75/25 SOLIQUA™ 100/33 (insulin glargine and lixisenatide injection) XULTOPHY® 100/3.6 (insulin degludec and liraglutide injection) --® Onset: 30-60 min Peak: 2-12 hours Duration: 18 - 24 hours Solution: Cloudy Comments: Mixture of 70% NPH, Human Insulin Isophane Suspension and 30% Regular, Human Insulin Injection. Recommended interval between dosing and meal initiation: 30 minutes. Mixing You should not attempt to change the ratio of this product by adding additional NPH or Regular insulin to the vial. If the physician has prescribed insulin mixed in a proportion other than 70% NPH and 30% Regular, you should use the separate insulin formulations (e.g. NPH and Regular insulin ) in the amounts recommended by the physician. All Unopened Novolin 70/30: • Keep all unopened Novolin 70/30 in the refrigerator between 36° to 46°F (2° to 8°C). • Do not freeze. Do not use Novolin 70/30 if it has been frozen. • If refrigeration is not possible, the unopened vial may be kept at room temperature for up to 6 weeks (42 days), as long as it is kept at or below 77°F (25°C). • Keep unopened Novolin 70/30 in the carton to protect from light. Novolin 70/30 in use: Vials • Keep at room temperature below 77°F (25°C) for up to 6 weeks (42 days). • Keep vials away from direct heat or light. • Throw away an opened vial after 6 weeks (42 days) of use, even if there is insulin left in the vial. • Unopened vials can be used until the expiration date on the Novolin 70/30 label, if the medicine has been stored in a refrigerator. Note: double mouse click to return to the top of the page Onset Continue reading >>

What Should Be Considered When Selecting Insulin Or Another Injectable Diabetes Product From The Fridge?

Detail-Document; 280316 Insulins differ from each other in regard to source (e.g., human, human insulin analog, pork [Canada only]) and duration of action (e.g., rapid-, short-, intermediate-, or long-acting). Human insulin does not actually come from humans; it is genetically engineered, but it is identical to the insulin produced by the human pancreas. Human insulin analogs are human insulin that has been modified to make the insulin act more quickly for use around mealtimes (e.g., Humalog, Apidra) or last longer (e.g., Levemir, Lantus). Mixtures of short- and longer-acting insulins are also available to reduce the number of injections for patients requiring both shorter- and longer-acting insulins. For example, Humulin 70/30 is 70% NPH (an intermediate-acting insulin) and 30% regular insulin (a short-acting insulin). It's a good idea to use separate bins or shelf alerts to distinguish among products that look similar. For example, Lantus and Apidra vials are both manufactured by Sanofi-Aventis and have similar packaging that has contributed to mix-ups with these products. Insulin most commonly comes in a concentration of 100 units per mL. This strength is referred to as U-100. Vials contain 10 mL, or 1000 units (100 units/mL x 10 mL/vial = 1000 units). A 500 unit per mL Humulin R (referred to as U-500) is available by prescription in the U.S. for people requiring large doses. If this very concentrated insulin is available in your pharmacy, it should be kept in a special place in the fridge to avoid mix-ups. Mistakenly dispensing 500 units per mL Humulin R in place of the 100 units per mL strength could result in a five-fold overdose. The patient's blood sugar could plummet, which could be fatal. Another uncommon insulin is pork insulin (Canada only). Some insulins ar Continue reading >>

[full Text] Update On Insulin Treatment For Dogs And Cats: Insulin Dosing Pens And | Vmrr

Editor who approved publication: Professor Takashi Agui Ann Thompson,1 Patty Lathan,2 Linda Fleeman3 1School of Veterinary Science, The University of Queensland, Gatton, QLD, Australia; 2College of Veterinary Medicine Mississippi State University, Starkville, MS, USA; 3Animal Diabetes Australia, Melbourne, VIC, Australia Abstract: Insulin therapy is still the primary therapy for all diabetic dogs and cats. Several insulin options are available for each species, including veterinary registered products and human insulin preparations. The insulin chosen depends on the individual patient's requirements. Intermediate-acting insulin is usually the first choice for dogs, and longer-acting insulin is the first choice for cats. Once the insulin type is chosen, the best method of insulin administration should be considered. Traditionally, insulin vials and syringes have been used, but insulin pen devices have recently entered the veterinary market. Pens have different handling requirements when compared with standard insulin vials including: storage out of the refrigerator for some insulin preparations once pen cartridges are in use; priming of the pen to ensure a full dose of insulin is administered; and holding the pen device in place for several seconds during the injection. Many different types of pen devices are available, with features such as half-unit dosing, large dials for visually impaired people, and memory that can display the last time and dose of insulin administered. Insulin pens come in both reusable and disposable options. Pens have several benefits over syringes, including improved dose accuracy, especially for low insulin doses. Keywords: diabetes, mellitus, canine, feline, NPH, glargine, porcine lente Insulin therapy is the cornerstone of management for dia Continue reading >>

New Insulin And Crashing

This last week I had to switch Bender over to a new insulin. Vetsulin is no longer available and it is unknown how long it will be till it is. These last few months have been great. I got Bender regulated. Down to 22ml per shot, he was up to 37 at one point. Healthy eating on a home cooked diet. And in general a happy dog. That all ended this week. I started Bender out on the normal measurement. It is some thing like .75 units per kilogram. Bender is 45 lb = 20.4116 kg x .75 = 15 units. My vet recommended Novolin N and I could get the generic from Walmart called ReliOn N. Which I did. He got 15 units per shot the first day. That night he crash. Peanut Butter and carrots to the rescue. The next night the same thing. By the third day I changed his dose to 10 units. He started to get worse. He was crashing twice a day. Last night was scary. Woke at 1:30 to Bender milling around. He was crashing. I got him PB and carrots. After ten minutes he was ok. We went back to bed. 20 minutes later he is up milling around, worse than before. Falling over, bumping into every thing. He has never been this bad. I tested his level. 41. My meter doesn’t read below 40. It just says low. This time I give him some honey and 1/3 of his food for a meal. After 25 minutes I test his glucose level. It was 61. Not high enough. So I gave him the rest of his food and sat up with him for another 45 mins. At that point he was 109 and we went back to bed. At 9am I tested him after I fed him. 192. Excellent. He got 7 units. By 6. He was crashing again. No time to test. I gave him a spoon full of honey and then his meal. Afterwards I tested. He was at 90. No shot. Some thing is going on here. There has to be a huge difference between Vetsulin and Novolin – N. Upon some research, there is. I honestly n Continue reading >>

Selected Important Safety Information

Tresiba® is contraindicated during episodes of hypoglycemia and in patients with hypersensitivity to Tresiba® or one of its excipients Never Share a Tresiba® FlexTouch® Pen Between Patients, even if the needle is changed. Sharing poses a risk for transmission of blood-borne pathogens Monitor blood glucose in all patients treated with insulin. Changes in insulin may affect glycemic control. These changes should be made cautiously and under medical supervision. Adjustments in concomitant oral anti-diabetic treatment may be needed Hypoglycemia is the most common adverse reaction of insulin, including Tresiba®, and may be life-threatening Tresiba® (insulin degludec injection) is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus. Tresiba® is not recommended for treating diabetic ketoacidosis or for pediatric patients requiring less than 5 units of Tresiba®. Tresiba® is contraindicated during episodes of hypoglycemia and in patients with hypersensitivity to Tresiba® or one of its excipients Never Share a Tresiba® FlexTouch® Pen Between Patients, even if the needle is changed. Sharing poses a risk for transmission of blood-borne pathogens Monitor blood glucose in all patients treated with insulin. Changes in insulin may affect glycemic control. These changes should be made cautiously and under medical supervision. Adjustments in concomitant oral anti-diabetic treatment may be needed Hypoglycemia is the most common adverse reaction of insulin, including Tresiba®, and may be life-threatening. Increase monitoring with changes to: insulin dose, co-administered glucose lowering medications, meal pattern, physical activity; and in patients with hypoglycemia unawareness or renal or hepatic impairment Accidental mix-ups betwe Continue reading >>

Insulin Isophane Human/insulin Regular Human (otc)

Type 1 Diabetes Mellitus Suggested guidelines for beginning dose Ketones moderate or less: 0.5 U/kg/day SC Ketones large: 0.7 U/kg/day SC Typically, 50-75% of total daily dose is given as intermediate- or long-acting insulin May use this combination product if the dosage ratio of NPH (isophane) to regular is 2:1 Type 2 Diabetes Mellitus Suggested guidelines for beginning dose; adjust according to blood glucose levels Initial dose: 0.5-1 units/kg/day in divided doses Typically, 50-75% of total daily dose is given as intermediate- or long-acting insulin May use this combination product if the dosage ratio of NPH (isophane) to regular is 2:1 Administer within 15 min before a meal or immediately after a meal Store unopened vials/pens refrigerated; do not freeze Opened (in-use) product may be stored at ambient room temperature (below 86°F [30°C]) and away from heat and light Dosage Adjustment Strategies Dosage of human insulin, which is always expressed in USP units, must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect Dose adjustments should be based on regular blood glucose testing (See Dosage Adjustment Strategies) Adjust to achieve appropriate glucose control Adjust only one insulin dose at a time Correct hypoglycemia first Correct highest blood sugars next If all blood sugars are high (within 2.75 mmol/L [50 mg/dL]): correct morning fasting blood glucose 1st Many sliding scales exist to determine exact insulin dose based on frequent blood glucose monitoring - Commonly written for q4hr blood glucose test - Sliding scale coverage usually begins after blood glucose >11 mmol/L (200 mg/dL) - If coverage is needed q4hr x 24 hr, then base insulin dose is adjusted first; sliding scale doses may be adjusted upward Continue reading >>

Insulin Dosing Made Simple

I have found, in my years of practicing correctional medicine, that few practitioners who come to corrections are comfortable with insulin dosing. In my experience, this is especially true for physician assistants and nurse practitioners, but many physicians have problems, too. Insulin dosing can be complicated and tricky at times, but for most patients, 10 simple rules will get you to where you need to be. We first need to cover some groundwork and some terms. Insulin terminology can be confusing. First, it is very important to remember that this discussion applies to type 1 diabetics only. Type 2 diabetics sometimes use insulin, but that’s a “whole ‘nother ballgame.” There are two types of insulin used for two very different purposes when treating type 1 diabetics. The first is basal insulin, which is used to replace the insulin that the normal pancreas releases constantly—whether we eat or not. Long-acting insulin is used to provide coverage for the basal metabolic needs of type 1 diabetics. Examples are insulin glargine (Lantus) and insulin detemir (Levemir). The most commonly used long-acting insulin is Lantus, so I am going to use that name in this article. (I have no financial ties to the maker of Lantus—I use that name because it is the name most commonly used by patients). The second type of insulin that type 1 diabetics need is short-acting insulin, which is given to cover the carbohydrates in the food they eat. Short-acting insulins are given just before a meal or snack and, ideally, the dose should vary depending on how many carbohydrates are in the food. Examples of short acting insulins are insulin regular, insulin aspart (Novolog) and insulin lispro (Humalog). Again, I will use the term Humalog in this article because it is the term most often Continue reading >>

When Does Humulin Insulin Peak?

Like all regular insulins, Humulin R helps to prevent your blood sugar level from rising excessively after meals. The activity of Humulin R typically peaks two to four hours after you inject the medication. To synchronize the peak activity of Humulin R with the blood sugar peak associated with eating, you inject this form of insulin approximately 20 to 30 minutes before meals. Humulin N contains insulin in a chemical suspension that slows and prolongs its release. The peak activity of Humulin N typically occurs approximately eight hours after your injection. The duration of activity is approximately 12 to 16 hours. The activity profile of Humulin N makes it useful for maintaining a relatively constant level of insulin in your bloodstream if administered twice daily. This helps keep your blood sugar level steady between meals. Humulin 70/30 is a premixed formulation containing 70 percent Humulin N and 30 percent Humulin R. The premixed drug is convenient if your doctor prescribes both regular and NPH insulin. Two activity peaks occur with this combination medication; one approximately two hours after injection from the regular insulin and a second lower peak approximately 10 hours after injection from the NPH insulin. Variability in Peak Activity The reported peak activity times for various types of Humulin are averages; your experience may be different. After using Humulin for several weeks, you and your doctor may discover from your home glucose monitoring that you are experiencing peak activity earlier or later than the reported average. If this occurs, the timing of your injections may need to be adjusted. Do not change the dose or timing of your insulin injections unless you talk with your doctor. The peak activity of your insulin dose may also change from one day t Continue reading >>

Humulin 70/30 Dosage

There is no standard dosage of Humulin 70/30 that will work for all people, so dosing must be individualized for each person. In order to help determine an appropriate dose, your healthcare provider may recommend carbohydrate counting and ask you to measure your blood sugar before and after meals. The medication is typically administered twice a day, about 30 minutes before meals. The dose of Humulin 70/30 (NPH insulin / regular insulin ) that your healthcare provider recommends will vary, depending on a number of factors, including: Your blood sugar goals (which can vary from person to person) Other medications you are taking, including other diabetes medications As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so. Dosing for Humulin 70/30 must be individualized for each different person. There is no "standard" Humulin 70/30 dose that will work for all people or even for the same person in all situations. Humulin 70/30 is made up of two different insulins, 70 percent intermediate-acting (NPH insulin) and 30 percent short-acting (regular insulin). It is typically taken twice a day before meals (often about 30 minutes before eating). Your healthcare provider may ask you to measure your blood sugar before and after meals and may also recommend carbohydrate counting. Both of these things can help you and your healthcare provider know how to dose your Humulin 70/30. In some situations, you and your healthcare provider may prefer "aggressive" insulin dosing, which may help reduce the risk of long-term diabetes complications but increases the risk of dangerously low blood sugar (hypoglycemia). Some people may need more relaxed insulin dosing, especially if they live alone (making it difficult to adequately resp Continue reading >>

Insulin (medication)

"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[7] The wholesale cost in the developing world is about US$2.39 to $10.61 per 1,000 iu of regular insulin and $2.23 to $10.35 per 1,000 iu of NPH insulin.[8][9] In the United Kingdom 1,000 iu of regular or NPH insulin costs the NHS 7.48 pounds, while this amount of insulin glargine costs 30.68 pounds.[5] Medical uses[edit] Giving insulin with an insulin pen. Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacid Continue reading >>

What Is Humulin 70/30 Kwikpen?

Before you receive DARZALEX®, tell your healthcare provider about all of your medical conditions, including if you: have a history of breathing problems have had shingles (herpes zoster) are pregnant or plan to become pregnant. DARZALEX® may harm your unborn baby. Females who are able to become pregnant should use an effective method of birth control during treatment and for at least 3 months after your final dose of DARZALEX®. Talk to your healthcare provider about birth control methods that you can use during this time. are breastfeeding or plan to breastfeed. It is not known if DARZALEX® passes into your breast milk. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. DARZALEX® may be given alone or together with other medicines used to treat multiple myeloma. Your healthcare provider will decide the time between doses as well as how many treatments you will receive. Your healthcare provider will give you medicines before each dose of DARZALEX® and on the first day after each dose of DARZALEX® to help reduce the risk of infusion reactions. If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment. Infusion reactions. Infusion reactions are common with DARZALEX® and can be severe. Your healthcare provider may temporarily stop your infusion or completely stop treatment with DARZALEX® if you have infusion reactions. Tell your healthcare provider right away if you get any of the following symptoms: shortness of breath or trouble breathing dizziness or lightheadedness (hypotension) cough wheezing throat tightness runny or stuffy nose headache itching nausea vomiting chills fever Changes in blood tests. DARZALEX� Continue reading >>

Conversion Chart For Humulin R U-500 Insulin Dose

When using a U-100 insulin syringe or a tuberculin syringe, use this handy U-500 Conversion Chart. Humulin U-500 Conversion Chart Mar 2011 Continue reading >>