diabetestalk.net

Humalog Plain

What Are The Possible Side Effects Of Insulin Lispro (humalog, Humalog Cartridge, Humalog Kwikpen, Humalog Pen)?

What Are The Possible Side Effects Of Insulin Lispro (humalog, Humalog Cartridge, Humalog Kwikpen, Humalog Pen)?

HUMALOG (insulin lispro) Injection DESCRIPTION HUMALOG® (insulin lispro injection) is a rapid-acting human insulin analog used to lower blood glucose. Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Insulin lispro differs from human insulin in that the amino acid proline at position B28 is replaced by lysine and the lysine in position B29 is replaced by proline. Chemically, it is Lys(B28), Pro(B29) human insulin analog and has the empirical formula C257H383N65O77S6 and a molecular weight of 5808, both identical to that of human insulin. HUMALOG has the following primary structure: HUMALOG is a sterile, aqueous, clear, and colorless solution. Each milliliter of HUMALOG U-100 contains insulin lispro 100 units, 16 mg glycerin, 1.88 mg dibasic sodium phosphate, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.0197 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. Each milliliter of HUMALOG U-200 contains insulin lispro 200 units, 16 mg glycerin, 5 mg tromethamine, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.046 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. font size A A A 1 2 3 4 5 Next What is Type 2 Diabetes? The most common form of diabetes is type 2 diabetes, formerly called non-insulin dependent diabetes mellitus or "adult onset" diabetes, so-called because it typically develops in adults over age 35, though it can develop at any age. Type 2 diabetes i Continue reading >>

Combination Insulin Products Increase Opportunity For Errors

Combination Insulin Products Increase Opportunity For Errors

Combination Insulin Products Increase Opportunity for Errors Kate Kelly, PharmD, Editor, ISMP Medication Safety Alert! Community/ Ambulatory Care Edition, and Allen J. Vaida, PharmD, FASHP, Executive Director, Institute for Safe Medication Practices The Institute for Safe Medication Practices (ISMP) is concerned about a growing number of medication errors involving commercially available insulin mixtures. For example, ISMP recently received several reports about mix-ups between Humalog Mix 75/25 (75% insulin lispro protamine suspension and 25% insulin lispro injection [rDNA]) and Humulin 70/30 (70% human insulin isophane suspension [NPH] and 30% human insulin injection [regular] [rDNA]). Several locations have reported multiple mix-ups where Humalog (insulin lispro) was erroneously prescribed as a 70/30 mixture (no such ratio exists) and Hu-mulin 70/30 was dispensed and administered in error. In 1 instance, ISMP learned that an internist who prescribed Humalog 70/30 was not sure of the strength, but the internist intended for the patient to receive Humalog Mix 75/25. Also, ISMP has had cases where plain Humalog was prescribed for a patient, but the patient was given Humalog Mix 75/25. In addition, Humalog Mix 75/25 was accidentally entered into a computer when plain Humalog was prescribed. To add to the potential problems, in late September of 2002, Novo Nordisk announced the availability of NovoLog Mix 70/30 (70% insulin aspart [rDNA origin] protamine suspension and 30% insulin aspart [rDNA] injection) along with its currently available Novolin 70/30 (70% NPH, human insulin iso-phane suspension, and 30% regular, human insulin injection [rDNA]). The drug names and similar strengths of these combination products could cause confusion, and mix-ups between the different i Continue reading >>

Humalog Dosage

Humalog Dosage

Your healthcare provider will recommend a Humalog dosage based on how you respond to the medication and your current dose of other insulins. There is no standard dose that will work for the same person in all situations. For example, smaller Humalog doses are necessary if you eat a low-carbohydrate meal, while larger doses are necessary after meals with a high carbohydrate content. The dose of Humalog ( insulin lispro ) your healthcare provider recommends will vary, depending on a number of factors, including: How you respond to Humalog (especially as measured by your blood sugar levels) Other medications you are taking, including other diabetes medications As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so. This article refers to plain Humalog. Humalog is also available in combination with an intermediate-acting insulin ( Humalog Mix75/25 and Humalog Mix50/50 ). Humalog is dosed much like any other rapid-acting insulin. That means there is no "standard" dose that will work for all people, or even for the same person in all situations. Humalog is used to control blood sugar after meals. It can be taken any time within 15 minutes before or after a meal. Once you have taken a dose, you must start eating within 15 minutes. Otherwise, you may experience dangerously low blood sugar (hypoglycemia). You may be asked to measure your blood sugar before and after meals, and your healthcare provider may recommend carbohydrate counting. Both of these things can help you and your healthcare provider know how to figure your Humalog dose. In general, smaller doses of Humalog are necessary after meals with a low carbohydrate content, while larger doses are necessary after meals with a high carbohydrate content. Continue reading >>

Humalog Kwikpen

Humalog Kwikpen

D.D. Family T1 since 9/05, pump since 4/06, CGMS since 10/07 Anyone using this pen? I'm taking a mini pump break for a vacation, and my doctor gave me samples of this. However, it's acting differently from other pens I've used. I've only used the novo pens before, and with those, the knob is completely flat against the pen, then spins upward as you dial your dose. When you deliver it, you press the button down, and it's completely flat again. My Kwikpen the knob is never flat against the pen. It stays popped up. When you dial the dose, it pops up further, then when I push the knob down, it's flat against the pen, but when I let go of it, it pops back up. Is this normal, or did I get a defective pen? Should the knob stay completely depressed? I have the disposable ones from humalog. Have no clue what they are called, doesn't say anything about Kwik on mine. But my knob goes flat. I can send you some if you want. I have a million and probably will never use them. Just here in case of an emergency. [FONT=Century Gothic][SIZE=3][COLOR=Magenta]Kris[/COLOR][/SIZE][/FONT][FONT=Lucida Sans Unicode] Continue reading >>

Welcome To The Humalog® Family Of Insulins.

Welcome To The Humalog® Family Of Insulins.

Humalog® is used to treat people with diabetes for the control of blood sugar. Humalog® Mix75/25™(75% insulin lispro protamine suspension and 25% insulin lispro injection) and Humalog® Mix50/50™(50% insulin lispro protamine suspension and 50% insulin lispro injection) are used to treat adults with diabetes for the control of high blood sugar. Do not share your Humalog, Humalog Junior, Humalog Mix75/25, or Humalog Mix50/50 KwikPens, cartridges, reusable pen compatible with Lilly 3 mL cartridges, or syringes with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them. The Humalog contained in the Humalog U-200 KwikPen should ONLY be injected with the Humalog U-200 KwikPen. Do NOT withdraw Humalog U-200 from the pen using a syringe. It could result in an overdose causing severe low blood sugar which may put your life in danger. Do not change the insulin you use without talking to your healthcare provider. Changes may make you more likely to experience low or high blood sugar. Changes should be made cautiously under the supervision of your healthcare provider. When used in a pump, do not mix or dilute Humalog U-100 with any other insulin or liquid. Do NOT use Humalog U-200, Humalog Mix75/25 or Humalog Mix50/50 in a pump. These insulins start working faster than other insulins that contain regular human insulin. You should take Humalog within fifteen minutes before eating or right after eating a meal. You should take Humalog Mix75/25 and Humalog Mix50/50 within fifteen minutes before eating. Do not use Humalog Mix75/25 or Humalog Mix50/50 if they have solid particles or clumps in them. Humalog Mix75/25 and Humalog Mix50/50 should be mixed carefully before each use and should be cloudy or mi Continue reading >>

Insulin Lispro

Insulin Lispro

Insulin lispro, sold under the brand name Humalog among others, is a fast acting insulin analog. It was first approved for use in the United States in 1996, making it the first insulin analog to enter the market.[2] Engineered through recombinant DNA technology, the penultimate lysine and proline residues on the C-terminal end of the B-chain are reversed. This modification does not alter receptor binding, but blocks the formation of insulin dimers and hexamers. This allows larger amounts of active monomeric insulin to be immediately available for postprandial injections.[3] Insulin lispro has one primary advantage over regular insulin for postprandial glucose control. It has a shortened delay of onset, allowing slightly more flexibility than regular insulin, which requires a longer waiting period before starting a meal after injection. Both preparations should be coupled with a longer acting insulin (e.g. NPH insulin) for good glycemic control. Medical uses[edit] Insulin lispro is an FDA approved drug used to treat people living with Type 1 diabetes or Type 2 diabetes.[4] Insulin lispro has non-FDA labeled uses for diabetic neuropathy prevention and cardiovascular disease prevention.[4] Side effects[edit] Common side effects include skin irritation at the site of injection, hypoglycemia, hypokalemia, and lipodystrophy.[4] Other serious side effects include anaphylaxis, and hypersensitivity reactions.[4] Contraindications[edit] Do not administer insulin lispro during episodes of hypoglycemia, or if the patient has a hypersensitivity to insulin lispro or any of its excipients.[4] Cost[edit] In the United States as of 2015 the cost is between 10.06 and 29.36 USD per 100 units.[5] In Europe the price is far lower. The cost in the UK is between £1.66 (about $2.50) and £1.9 Continue reading >>

Humalog 100iu/ml Cartridge

Humalog 100iu/ml Cartridge

Taking Insulin lispro with alcohol may affect blood glucose levels in patients with diabetes. Humalog 100IU/ml Cartridge is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor. Humalog 100IU/ml Cartridge is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive. Humalog 100IU/ml Cartridge should be used with caution in patients with kidney disease. Dose adjustment of Humalog 100IU/ml Cartridge may be needed. Please consult your doctor. Frequent and regular monitoring of blood glucose levels in advised for dose adjustment. Humalog 100IU/ml Cartridge should be used with caution in patients with liver disease. Dose adjustment of Humalog 100IU/ml Cartridge may be needed. Please consult your doctor. .Frequent and regular monitoring of blood glucose levels in advised for dose adjustment. Continue reading >>

About Fast-acting Mealtime Insulin

About Fast-acting Mealtime Insulin

What is mealtime insulin? Mealtime insulins are fast-acting insulins that are taken immediately before or after meals. As you eat, your blood sugar naturally goes up, or “spikes.” Humalog® (a fast-acting insulin) works to manage those blood sugar spikes and may help keep your sugar levels in balance. Humalog should be taken within 15 minutes before eating or right after eating a meal. People who take Humalog will usually continue to take longer-acting insulin to help manage blood sugar levels at night and between meals. Taking mealtime insulin in addition to longer-acting insulin may help to control blood sugar levels throughout the day. Low blood sugar (hypoglycemia) is the most common side effect of Humalog that may be severe and cause unconsciousness (passing out), seizures, and death. Test your blood sugar levels as your doctor instructs. Talk to your doctor about low blood sugar symptoms and treatment. The orange area shows how blood sugar levels typically rise after meals. The pattern of insulin action may vary in different individuals or within the same individual. Comparing types of insulin Take a look at our overview below to find out about the different types of insulin. You’ll notice that there are differences in when the types of insulin reach your bloodstream, when they “peak” in your body, and how long they can last (length of time the insulin keeps lowering your blood sugar). Fast-acting insulin (also called rapid-acting) is absorbed quickly and starts working in about 15 minutes to lower blood sugar after meals. Humalog fast-acting insulin should be taken 15 minutes before eating or right after eating a meal. Depending on the type of diabetes you have, you may need to take Humalog with a longer-acting insulin or oral anti-diabetes medication. Continue reading >>

Humalog Side Effects

Humalog Side Effects

Generic Name: insulin lispro (IN soo lin LISS pro) Brand Names: HumaLOG, HumaLOG Cartridge, HumaLOG KwikPen, HumaLOG KwikPen (Concentrated) What is Humalog? Humalog (insulin lispro) is a fast-acting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Humalog is used to improve blood sugar control in adults and children with diabetes mellitus. Humalog is used to treat type 2 diabetes in adults. Humalog is also used to treat type 1 diabetes in adults and children who are at least 3 years old. Important information Humalog is a fast-acting insulin that begins to work very quickly. If you use this medication with meal, use it within 15 minutes before or just after you eat. Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. You should not use Humalog if you are having an episode of hypoglycemia (low blood sugar). Humalog is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels. Before taking this medicine You should not use Humalog if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar). Humalog should not be given to a child younger than 3 years old. Humalog should not be used to treat type 2 diabetes in a child of any age. To make sure Humalog is safe for you, tell your doctor if you have: liver or kidney disease; or low levels of potassium in your blood (hypokalemia). Tell your doctor if Continue reading >>

Humulin R Versus Humalog: A Side-by-side Comparison

Humulin R Versus Humalog: A Side-by-side Comparison

Diabetes is a disease that causes high blood sugar levels. Left untreated, high blood sugar levels can cause many problems, such as heart and blood vessel disease, stroke, kidney failure, and blindness. Humulin R and Humalog are two different types of insulin that can help lower your blood sugar level. These drugs work in slightly different ways. In general, insulin lowers your blood sugar level by signaling to your muscle and fat cells to use sugar from your blood. It also signals your liver to stop making sugar. Depending on the type and severity of your diabetes, you may need to take insulin. We’ll compare and contrast Humulin R and Humalog to help you decide if one may be a good choice to treat your diabetes. Humulin R is a brand name for regular insulin. It is a short-acting insulin. That means that it takes about 30 minutes to reach your bloodstream and works for about three to six hours. Humalog is a brand name for insulin lispro, which is a fast-acting insulin. It takes about 15 minutes to start working, but it only lasts two to four hours. The following table compares more features of these two drugs. Humulin R Humalog What drug is it? Regular insulin (short-acting insulin) Insulin lispro (fast-acting insulin) What’s it used for? Blood sugar control in people with diabetes Blood sugar control in people with diabetes Do I need a prescription to buy this drug? No Yes Is a generic version available? No No What forms does it come in? Injectable solution, available in a vial for use with a syringe Injectable solution, available in a vial for use with a syringe. Injectable solution, available in a cartridge that you use in a device called a KwikPen How much do I take? Your doctor will tell you what dose to inject. This depends on your blood sugar readings and the Continue reading >>

Humalog

Humalog

Humalog is a prescription medication approved to treat type 1 and type 2 diabetes. The insulin, which is injected within 15 minutes before or after meals, is designed to help control the blood sugar spike that occurs after meals. Potential side effects of Humalog include low blood sugar, skin reaction at the injection site, and thickening or pitting of the skin at the injection site. Humalog ( insulin lispro ) is a prescription form of insulin used to treat type 1 and type 2 diabetes . It is a rapid-acting insulin, used to help control the spike in blood sugar that occurs after meals. It is typically used in combination with a long-acting insulin. The medication can also be used in an insulin pump . This article refers to plain Humalog. Humalog is also available in combination with an intermediate-acting insulin ( Humalog Mix75/25 and Humalog Mix50/50 ). (Click Humalog Uses for more information, including possible off-label uses.) Humalog is manufactured by Eli Lilly and Company. Studies have shown that Humalog worked as well as regular human insulin. People with type 1 diabetes taking the drug may have a lower chance of nighttime hypoglycemia (low blood sugar), compared to those taking regular human insulin. Humalog is a form of insulin, which is a hormone that is naturally produced by the pancreas . This hormone is important for several functions, such as controlling blood sugar. Insulin helps the cells of your body remove glucose ("sugar") from your bloodstream. This sugar fuels your body's cells, giving them the energy they need to work properly. You may need to take insulin if your pancreas has trouble making enough insulin, which is the case in people with type 1 diabetes and in some people who have type 2 diabetes. Normally, your body is able to maintain proper Continue reading >>

Why Humalog® U-100?

Why Humalog® U-100?

You may have been taking a long-acting insulin for a while now. So why did your doctor prescribe another insulin? Well, it’s to help control the blood sugar spikes that happen naturally when you eat. Everyone gets them, but when you have diabetes you may need extra help controlling them. That’s where Humalog comes in. Humalog is different than your long-acting insulin. Long-acting insulin helps control your blood sugar throughout the whole day. Humalog is fast-acting insulin—it helps control the blood sugar spikes that happen naturally when you eat. Humalog is available in the Humalog U-100 KwikPen, which is portable and easy to use. And, since it shouldn’t be refrigerated after the first use, you can take it just about anywhere. Continue reading >>

Humalog Mix 75-25 Subcutaneous Reviews And User Ratings: Effectiveness, Ease Of Use, And Satisfaction

Humalog Mix 75-25 Subcutaneous Reviews And User Ratings: Effectiveness, Ease Of Use, And Satisfaction

IMPORTANT: About This Section and Other User-Generated Content on WebMD The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Continue reading >>

Humalog Uses

Humalog Uses

Humalog is used for treating type 1 and type 2 diabetes. It is a rapid-acting insulin that is specifically designed to help control the blood sugar spike that occurs after meals. The prescription medication is approved for use in both adults and children. Healthcare providers may also sometimes recommend off-label Humalog uses, such as for treating gestational diabetes. Humalog ( insulin lispro ) is a form of insulin used to help control blood sugar in people with type 1 and type 2 diabetes . This medication is rapid-acting and is used to control blood sugar after meals. Alternatively, Humalog can also be used in an insulin pump . The medication is designed to start working more quickly and has a shorter duration of action compared to regular human insulin. This article refers to plain Humalog. Humalog is also available in combination with an intermediate-acting insulin ( Humalog Mix75/25 and Humalog Mix50/50 ). Type 1 diabetes usually begins in young children and teenagers, although this is not always the case. People with this type of diabetes have a pancreas that produces little or no insulin. This means that such people need to have insulin on a regular basis to help keep their blood sugar at the right level. In healthy people without diabetes, insulin levels do not stay the same throughout the day; instead, they fluctuate in response to changes in blood sugar levels. In order to mimic the natural insulin changes that help keep blood sugar safely controlled, many healthcare providers recommend "basal-bolus" insulin regimens. These regimens often involve a longer-acting insulin to provide a basal insulin level (a relatively steady background level of insulin throughout the day). A rapid-acting insulin, such as Humalog, is added to provide the bolus (a quick, fast-ac Continue reading >>

Insulin Lispro (rx)

Insulin Lispro (rx)

Dosage Forms & Strengths Type 1 or 2 Diabetes Mellitus Rapid-acting human insulin analogue indicated to improve glycemic control in adults and children with type 1 or 2 diabetes mellitus Usual daily maintenance range is 0.5-1 unit/kg/day in divided doses; nonobese may require 0.4-0.6 unit/kg/day; obese may require 0.8-1.2 units/kg/day Intermediate- or long-acting insulin: Approximately one-third of the total daily insulin requirements SC Rapid-acting or short-acting, premeal insulin should be used to satisfy the remainder of the daily insulin requirements Type 2 diabetes mellitus Intermediate- or long-acting insulin: 10 units/day SC (or 0.1-0.2 unit/kg/day) at bedtime generally recommended Short-acting insulin: If necessary, start up to 4 units, 0.1 unit/kg SC within 15 min before each meal, or 10% basal dose; if A1C <8%, consider decreasing basal insulin dose by same amount Increase by 1-2 units or 10-15% qWeek or q2Weeks once self-monitoring of blood glucose (SMBG) is achieved (ADA guidelines 2018) Dosing Considerations Do not mix SC injection with insulin preparations other than NPH insulin Do not mix IV or continuous SC infusions with any other insulins Do NOT transfer Humalog U-200 from the KwikPen to a syringe for administration; the markings on the insulin syringe will not measure the dose correctly and can result in overdosage and severe hypoglycemia Do NOT perform dose conversion when using either the Humalog U-100 or U-200 KwikPens; the dose window shows number of insulin units to be delivered and no conversion is needed Do NOT mix Humalog U-200 with any other insulins Do NOT administer Humalog U-200 using a continuous subcutaneous infusion pump (i.e., insulin pump); insulin pump is to be used only for Humalog U-100 Do NOT administer Humalog U-200 intravenousl Continue reading >>

More in insulin