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# How Much Is A Unit Of Insulin?

For those who take rapid-acting insulin at mealtimes and want any degree of meal planning flexibility, it is necessary to apply something known as insulin-to-carb (I:C) ratios. Now, if the mere thought of having to do math at every meal sends shivers up your spine, don’t despair. This is something that even the “mathematically challenged” can master in no time. The Method Behind the Mathematics One of the basic assumptions we make in the use of I:C ratios is that dietary carbohydrates, which include sugars, starches and fiber, are responsible for raising blood sugar levels after meals. Fiber, however, is usually not counted since it does not break down completely and does not raise blood sugar levels. And fat and protein have minimal short-term effects, particularly when consumed as part of a carbohydrate-containing meal. The rapid-acting insulin that we give at mealtimes is designed to offset the blood sugar rise induced by the carbohydrates. In most cases, insulin analogs such as aspart (Novolog/Novorapid), lispro (Humalog) or glulisine (Apidra) are used at meals. However, Regular insulin (Humulin R, Novolin R) may be used, but it tends to be less effective because of its slower action. Whichever insulin is used, success comes from matching the dose to the amounts of carbohydrate eaten. This is where I:C ratios come in. The I:C ratio specifies how many grams of carbohydrate are “covered” by each unit of insulin. For example, a 1-unit-per-10-grams-of-carb (1:10) ratio means that one unit of insulin covers 10 grams of carbohydrate. A 1:20 ratio means that each unit covers 20 grams. Calculating a meal or snack dose becomes simple when you know your I:C ratio: Simply divide your carbs by your ratio. If each unit covers 10g and you have a modest 20g meal, you wil Continue reading >>

## Calculating Insulin Dose

You'll need to calculate some of your insulin doses. You'll also need to know some basic things about insulin. For example, 40-50% of the total daily insulin dose is to replace insulin overnight. Your provider will prescribe an insulin dose regimen for you; however, you still need to calculate some of your insulin doses. Your insulin dose regimen provides formulas that allow you to calculate how much bolus insulin to take at meals and snacks, or to correct high blood sugars. In this section, you will find: First, some basic things to know about insulin: Approximately 40-50% of the total daily insulin dose is to replace insulin overnight, when you are fasting and between meals. This is called background or basal insulin replacement. The basal or background insulin dose usually is constant from day to day. The other 50-60% of the total daily insulin dose is for carbohydrate coverage (food) and high blood sugar correction. This is called the bolus insulin replacement. Bolus – Carbohydrate coverage The bolus dose for food coverage is prescribed as an insulin to carbohydrate ratio. The insulin to carbohydrate ratio represents how many grams of carbohydrate are covered or disposed of by 1 unit of insulin. Generally, one unit of rapid-acting insulin will dispose of 12-15 grams of carbohydrate. This range can vary from 6-30 grams or more of carbohydrate depending on an individual’s sensitivity to insulin. Insulin sensitivity can vary according to the time of day, from person to person, and is affected by physical activity and stress. Bolus – High blood sugar correction (also known as insulin sensitivity factor) The bolus dose for high blood sugar correction is defined as how much one unit of rapid-acting insulin will drop the blood sugar. Generally, to correct a high bloo Continue reading >>

## How To Read An Insulin Syringe

As with all medicine, it is important to take the right dose each time ​ ​​Injecting yourself with the right dose of insulin is very important. This is why you need to know how to read a syringe. ​ Parts of an Insulin Syringe An insulin syringe has three parts: a needle, a barrel and a plunger. The needle is short and thin. It is made of a special material that allows the needle to slide through the skin easily with less pain. It comes with a cap to cover and protect it before it is used. The barrel is the plastic chamber that holds the insulin. It is marked with lines (calibrations) on the side. The lines show you how many units of insulin you are injecting. The plunger is the long thin rod that slides up and down the inside of the barrel. Its function is to either draw the insulin into the barrel or push the insulin out of the barrel through the needle. It has a rubber seal at the lower end to prevent insulin from leaking out. The rubber seal is fitted in such a way that it matches the line on the barrel. Syringes are meant for one-time use. Once used, they must be thrown away in special puncture-proof containers. How to Know What Syringe Size to Choose Insulin syringes come in different sizes. Syringe Size Number of Units the Syringe Holds 0.25 ml 25 0.30 ml 30 0.50 ml 50 1.00 ml 100 The larger the syringe size, the more insulin it can hold. When choosing the size of a syringe, consider: the number of units of insulin you need, and how well you can see the line markings on the barrel. Go for the smallest syringe size you can for the dose of insulin you need. This is because the lines on the barrel of small syringes are further apart and easier to see. How to Read a Syringe When measuring the amount of insulin, read from the top ring (needle side), and not the Continue reading >>

## 1 Unit Insulin Lowers Glucose By How Much? Calculating Insulin/carb Ratio

Remember High School algebra? Problem after problem wondering, when am I EVER going to use this? I sure remember thinking that on more than one occasion. Well, it turns out math does have more practical application than balancing your checkbook, keeping a budget, and calculating tips for servers. If you have type 2 diabetes, simple math may be crucial to keeping blood glucose under control. Why? As it turns out, the total amount of carbohydrates is the single most significant factor in maintaining blood glucose control. While many other factors play a role – such as meal timing, quality of food choices, balance of food groups etc – consistently maintaining the proper number of carbohydrates at meal times is most significant. Foods Really Matter This means it is not only key to choose complex carbohydrate (not simple sugars) whole foods sources, but also to be conscientious of the amount of carbohydrates you regularly consume. The amount of carbohydrates to eat per day is a hot issue of debate, with recommendations ranging from 20 to 200+ grams per day! In most cases 200 grams is way too much for a diabetic, research indicating that a lower carb diet is best for glucose control. Still, what is best for you will depend on many factors including your height, weight, age, physical activity level, and how your body responds to carbs. Some people are much more sensitive than others. For example, some people can eat brown rice and oatmeal, while in many cases people find it difficult to control their blood glucose while still eating these high carb foods. It will take working with a team of trusted professionals and probably some trial and error to find out what works best for you as an individual. In theory, the more consistent your carbohydrate consumption is (all other Continue reading >>

## How Much Does 1 Unit Of Insulin Bring Your Sugar Down

Question Originally asked by Community Member karen How Much Does 1 Unit Of Insulin Bring Your Sugar Down Using a chart to give my mother her insulin, sometimes it just seams its not bringing her sugar down to a lower level. Answer The “correction factor” is the term used for the amount of insulin a person needs in order to bring their blood sugar down to 120. It is different for everyone! Your mother’s endocrinologist should have a note of what this dose has been in the past, but you can also figure this out purely by conducting SAFE trial and error. If her blood sugar is at 200, try giving her one unit of insulin and test her blood sugar a half hour later, and then an hour later. If it’s still high, give another. For example, in MY body, if my blood sugar is at 200, I take two units of insulin to bring it down to 100 to 120. If I was going to be doing any exercise also at this time, i would only take one unit as my “correction factor” because the exercise would help bring the blood sugar down, too. Ginger You should know Answers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Continue reading >>

## U-500 Insulin: How Much Do You Know?

In the case of significant insulin resistance (defined as needing more than 200 units per day), multiple injections of insulin are needed throughout the day to keep the blood sugar in check. There is no written rule about the maximum volume of insulin that can be absorbed by the subcutaneous tissue at one time, but many prescribers will split an insulin dose into multiple injections when dose requirements are approaching 70 units in a single administration. An insulin pen can deliver 80 units, and the largest size insulin syringe can hold 100 units. So if your insulin dose is somewhere between 60 and 100 units, you might need more than one injection to deliver all of that insulin at one time. In order to avoid becoming a human needle cushion, concentrated insulins like Humulin R U-500 were developed. What is the difference in insulin concentrations? Most of the insulins on the market today are U-100 strength, meaning there are 100 units of insulin per mL. Examples are Regular insulin, NPH, 70/30 and other mixed insulin, glargine and detemir. U-500 concentrated insulin has 5 times the potency of U-100 insulin, giving 500 units per mL. By reducing the injected volume, better absorption, less injection discomfort and decreased number of injections can be experienced. Until recently, U-500 was the only concentrated form of insulin. Since 2015, two concentrated basal insulins U-300 {Glargine (Toujeo)} and U-200 {Degludec (Tresiba)} have become available in the US. These have a strength of 300 units per mL and 200 units mL, also resulting in smaller volumes injected. Dosing conversion charts are used to safely move from a U-100 insulin to U-500 insulin. Who needs U-500 insulin? Good candidates for U500 insulin are those whose total daily insulin dose exceeds 200 units per day Continue reading >>

## Type 2 Diabetes And Insulin

Getting Started When most people find out they have Type 2 diabetes, they are first instructed to make changes in their diet and lifestyle. These changes, which are likely to include routine exercise, more nutritious food choices, and often a lower calorie intake, are crucial to managing diabetes and may successfully lower blood glucose levels to an acceptable level. If they do not, a drug such as glyburide, glipizide, or metformin is often prescribed. But lifestyle changes and oral drugs for Type 2 diabetes are unlikely to be permanent solutions. This is because over time, the pancreas tends to produce less and less insulin until eventually it cannot meet the body’s needs. Ultimately, insulin (injected or infused) is the most effective treatment for Type 2 diabetes. There are many barriers to starting insulin therapy: Often they are psychological; sometimes they are physical or financial. But if insulin is begun early enough and is used appropriately, people who use it have a marked decrease in complications related to diabetes such as retinopathy (a diabetic eye disease), nephropathy (diabetic kidney disease), and neuropathy (nerve damage). The need for insulin should not be viewed as a personal failure, but rather as a largely inevitable part of the treatment of Type 2 diabetes. This article offers some practical guidance on starting insulin for people with Type 2 diabetes. When to start insulin Insulin is usually started when oral medicines (usually no more than two) and lifestyle changes (which should be maintained for life even if oral pills or insulin are later prescribed) have failed to lower a person’s HbA1c level to less than 7%. (HbA1c stands for glycosylated hemoglobin and is a measure of blood glucose control.) However, a recent consensus statement from Continue reading >>