How Does Use Of Insulin Lead To Hypokalemia?

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Insulin And Potassium

Insulin has a number of actions on the body besides lowering your blood glucose levels. Insulin suppresses the breakdown and buildup of glycogen, which is the storage form of glucose, it blocks fat metabolism and the release of fatty acids, and it puts potassium into the cells by activating the sodium-potassium cellular channels. Insulin stimulates the uptake of glucose and potassium in all cells of the body but primarily fuels the muscle cells as well as some of the fat cells. In type 2 diabetes or metabolic syndrome (a form of metabolic disease), insulin is not functioning up to its normal level. The cells of the body become resistant to insulin and the blood sugar levels are elevated. The serum potassium (K+) level is a reflection of the total body stores of potassium, although it can be inaccurate in some conditions that affect the distribution of potassium in the body’s cells. The plasma potassium level determines the resting potential of the cells of the body. A person can have low potassium (hypokalemia) or high potassium (hyperkalemia), both of which are asymptomatic conditions that can be serious as they both cause heart arrhythmias. The Relationship between Insulin and Continue reading >>

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Popular Questions

  1. cybron

    Can you plz tell me why insulin cuZ hypokalemia???

  2. Master shifu

    Insulin results Hypokalemia just by increasing the activity of H*K ATPase pump. So insulin only shifts the K+ from the extracellular compartment to the intracellular compartment, it doesn't decrease the total K+ content of the body........remember it......that's why during management of Hyperkalemia 1st initial therapy is done by giving Insulin + Glucose combination which usually needs 30 minutes to come into action........Hope it helps

  3. cybron

    Thanks master but i heard there is increase activity of Na/K pump not H/K pump..can u plz clarify??
    If H/K pump increases then acid production also increases??

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