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How Does Pcos Cause Insulin Resistance?

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What Causes Insulin Resistance?

Insulin Resistance has many factors that contribute to its presence in the body. In essence, our environment and lifestyles have evolved too rapidly for our bodies to keep pace. We are still genetically “wired” to thrive on the entrenched habits of our ancestors who consumed different, nutrient-rich foods, a diet low in carbohydrates, and also sustained greater levels of movement and exercise. Some women might also have a genetic predisposition to Insulin Resistance. Others develop Insulin Resistance through unhealthy lifestyles. Over time, the above factors have damaged the complex ability of our bodies’ cells to properly utilize insulin to convert glucose to energy. Unhealthy diets cause the pancreas to overproduce insulin that then overwhelms the cells reducing their sensitivity to insulin and impairing the vital process whereby glucose passes through the cell membrane to be converted into energy. Effects of Insulin Resistance Left unchecked, Insulin Resistance can cause a number of negative effects in the body: The de-sensitized cell membrane causes the “rejected” insulin to stay in the bloodstream where it causes a variety of conditions, including the unbalanced horm Continue reading >>

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Popular Questions

  1. Mimi's

    Hi,
    I have recently been diagnosed with Polycystic Ovaries which I believe is related to insulin resistance or vice versa. I am now put on metformin 500 mg thrice a day. However, even on a sparse diet, I am unable to lose weight. I would like to know if the poly cystic ovaries are under control, will my system still be insulin resistant? I am worried as my food habits are good and I walk a lot every day and I don't want to suffer from this condition. Thanks

  2. catherinecherub

    Hi @Mimi"s and welcome to the forum.
    I will tag @Brunneria who may be able to answer your queries.

  3. Brunneria

    Thanks @catherinecherub
    Hi and welcome @Mimi's
    You said
    Mimi's said: ↑
    Hi,
    I have recently been diagnosed with Polycystic Ovaries which I believe is related to insulin resistance or vice versa. I am now put on metformin 500 mg thrice a day. However, even on a sparse diet, I am unable to lose weight. I would like to know if the poly cystic ovaries are under control, will my system still be insulin resistant? I am worried as my food habits are good and I walk a lot every day and I don't want to suffer from this condition. Thanks And there is a lot in there
    so i will try and take things one at a time (although please remember that i am not a medical professional, just someone with PCOS!)
    Ok, so PCOS is a situation where your hormones are not working as normal - they are being produced on the wrong quantities - causing multiple cysts on the ovaries, with all those symptoms that we know and love, eh? Furriness, weight gain, insulin resistance, hunger, carb cravings, infertility, etc.
    The insulin resistance is a result of the hormones (it happens to type 2 diabetics), and quite a few PCOSers become type 2 by middle age. It sort of comes with the territory, I am afraid.
    The insulin resistance => hunger and carb cravings and (usually) weight gain.
    The fatter we get, the more insulin resistance we get, and the more symptoms of PCOS we get.
    As you can see, it is a vicious circle.
    But worry not! There are answers to each of the steps in the circle.
    You have been given metformin - that works to lower blood glucose a little, suppresses appetite a little, and reduces insulin resistance (this is key). What it doesn't do is work on the hormones themselves, or why your hormones are out of wack.
    Diet is the biggest weapon you have. PCOSers usually respond excellently to Low Carb diets - so you may want to think about that, if you havent started already.
    Low Carbing also helps reduce carb cravings (which is GREAT) and often enables weight loss. You have already discovered how difficult it is for us PCOSers to lose weight. I have the same problem. But orthodox low fat high carb diets and portion reduction make the carb cravings worse, and the weight loss well nigh impossible. I would starve myself until the cravings overwhelmed me, then binge. Now i low carb, i am never hungry, and i don't crave. It is bliss.
    So, can you see how it all fits together?
    High carb, low cal diet => cravings and weight gain => increased insulin resistance => escalating spiral.
    On the other hand
    Low carb diet + metformin => reduced insulin resistance, reduced cravings, hopefully weight loss => reduced insulin resistance.
    If we can get slim, our hormones tend to improve. The fatter we are, the worse all our symptoms seem to get.
    Hope that helps!
    And please, if there are any other PCOSers out there, let me know if you agree/disagree.

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