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High Fasting Insulin Levels

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Insulin Resistance

What is insulin resistance? Insulin is a hormone that facilitates the transport of blood sugar (glucose) from the bloodstream into cells throughout the body for use as fuel. In response to the normal increase in blood sugar after a meal, the pancreas secretes insulin into the bloodstream. With insulin resistance, the normal amount of insulin secreted is not sufficient to move glucose into the cells – thus the cells are said to be “resistant” to the action of insulin. To compensate, the pancreas secretes insulin in ever-increasing amounts to maintain fairly adequate blood-sugar movement into cells and a normal blood-sugar level. What are some insulin resistance symptoms? There are usually no obvious, outward signs of insulin resistance. However, when you are severely insulin resistant, dark patches of skin called acanthosis nigricans can develop on the back of the neck. Sometimes a dark ring forms around the neck. These dark patches can also occur on the elbows, knees, knuckles and armpits. More importantly, insulin has less visible effects on metabolic reactions throughout the body, including converting calories into fat. Insulin resistance influences the liver enzymes that p Continue reading >>

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  1. Jennifer72

    Fasting Insulin Level after 12-20 Hour Fast

    Had a fasting insulin blood test done at lab yesterday morning at 8:30 AM. It's the first time I've done it. Was curious. Only cost me like $26 to find out. I already knew I was highly insulin resistant type 2. i.e. I know that 1 unit of regular insulin only covers 2 mg/dL of blood glucose (as a corrective dose).
    I hadn't eaten any solid food before blood test, except for 20 hours earlier. I had coffee about 12 1/2 hours before test.. Nothing after the coffee.
    My Fasting Insulin was 12.9 uIU/ml and my fasting blood glucose was 124 mg/dL. (Normal fasting insulin range is 2.6 to 24.9 according to the blood test sheet).
    My calculated HOMA-IR score is then (12.9*124)/405 = 3.95. A score of 1.0 or less is normal from what I've read -- i.e. not insulin resistant.
    Anyways, since this is the first time I've done this test, I'd appreciate if anyone could chime in and tell me all they can about what I just found out with the test.
    Is there any way to determine how strong my pancreas is with this test? Or should I follow this fasting insulin test with another in a couple days where I drink like 100g of glucose 1 hour before the test? If the fasting insulin level is the same, then my pancreas is doing all it can do when fasting even right?

  2. Nicoletti

    I've never had any type of insulin test and it's never occurred to me to have one. My thought is with the way I eat my blood sugars are decent and that's all I care about.

  3. Jennifer72

    Originally Posted by Nicoletti
    I've never had any type of insulin test and it's never occurred to me to have one. My thought is with the way I eat my blood sugars are decent and that's all I care about. Well I've done everything I can with respect to eating and can't get blood sugar below 110-135 range all day. So I am concerned about it. I am thinking my pancreas might be weakened too much.. but again you've seen the amount of insulin it's putting out. 12.9 .. normal is down to 2.9 .. so I guess it still must be somewhat strong? I'm just highly resistant.

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