Comprehensive List Of Diabetes Medications
Understanding Type 1 and Type 2 Diabetes Diabetes occurs when your body no longer makes or uses insulin as it’s intended to. Insulin is a naturally occurring substance in the body, but some people don’t make enough of it or their cells become insulin resistant. Diabetic patients must manage higher than normal blood sugar (or glucose) levels in the body. Diabetes is classified into two types (Type 1 and Type 2). Diabetics of both types require medicines to normalize blood glucose levels. If the doctor says you’re diabetic, he or she will prescribe drugs for Type 1 and Type 2 diabetes. It’s good to know about the universe of treatment options diabetics have today. Here’s a comprehensive list of available diabetes medications along with links to Type 1 and Type 2 Diabetes medication prices that will help you save up to 90% off U.S. retail prices. You may also find our Cheat Sheet helpful: 12 Ways to Save Money on Your Diabetes Medications [Cheat Sheet] Type 1 Diabetes Medications Short-Action Insulin Brand names: Novolin and Humulin (regular insulin) are two commonly prescribed, short-acting drugs your doctor may prescribe. Rapid-Action Insulin Brand names: Levemir FlexPen and NovoLog Flexpen are two commonly prescribed rapid action insulins. Brand name: Humalog Pen (insulin lispro) Brand name: Apidra (insulin glulisine) Intermediate-Action Insulin Brand name: Novolin N and Humulin N Pen (insulin isophane) are two intermediate-action insulins your doctor may prescribe. Long-Action Insulin Brand name Tresiba (insulin degludec) Brand name Levemir Flexpen (insulin detemir) Brand name Lantus Vials (insulin glargine) Brand name Toujeo (insulin glargine) Combination Medications Insulin Brand name: Ryzodeg Brand name: NovoLog Mix 70/30 Brand name: Novolin 70/30 Brand na Continue reading >>
Sanofi Says Mylan Infringing 18 Insulin Patents
Law360, New York (October 26, 2017, 3:33 PM EDT) -- Sanofi filed a patent infringement suit Tuesday in New Jersey federal court alleging Mylan’s planned generic version of Sanofi’s insulin pen, Lantus, infringes 18 of its patents. Sanofi said in the complaint that since Mylan informed the company last month that it was seeking U.S. Food and Drug Administration approval to sell generic versions of Sanofi’s Lantus and Lantus SoloSTAR once-a-day insulin medication owned by Sanofi, it has sought a compromise with Mylan but that Mylan has not supplied it with any information. Mylan has not... Continue reading >>
Tresiba
TRESIBA® (insulin degludec) for Injection DESCRIPTION TRESIBA (insulin degludec injection) is a long-acting basal human insulin analog for subcutaneous injection. Insulin degludec is produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae followed by chemical modification. Insulin degludec differs from human insulin in that the amino acid threonine in position B30 has been omitted and a side-chain consisting of glutamic acid and a C16 fatty acid has been attached (chemical name: LysB29(Nε-hexadecandioyl-γ-Glu) des(B30) human insulin). Insulin degludec has a molecular formula of C274H411N65O81S6 and a molecular weight of 6103.97. It has the following structure: Figure 1: Structural Formula of TRESIBA TRESIBAis a sterile, aqueous, clear, and colorless solution that contains insulin degludec 100 units/mL(U-100)or 200 units/mL(U-200). Inactive ingredients for the 100 units/m Lare: glycerol 19.6 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 32.7 mcg/m Land water for injection. Inactive ingredients for the 200 units/m Lare glycerol 19.6 mg/mL, phenol1.50 mg/mL, metacresol 1.72 mg/mL, zinc 71.9 mcg/m Land water for injection. TRESIBA has a pH of approximately 7.6. Hydrochloric acid or sodium hydroxide may beadded to adjust pH. font size A A A 1 2 3 4 5 Next What is Type 2 Diabetes? The most common form of diabetes is type 2 diabetes, formerly called non-insulin dependent diabetes mellitus or "adult onset" diabetes, so-called because it typically develops in adults over age 35, though it can develop at any age. Type 2 diabetes is diagnosed more often in people who are overweight or obese, and who are not physically active. Type 2 diabetes is an illness in which the body does not process ingested sugars (glucose) properly. In type Continue reading >>
Where Is Generic Insulin?
When I turned 65 last month, it was time to deal with that dreaded entity, Medicare. It was a confusing few weeks, but I was careful to read everything sent to me, trying to sort it all out. The biggest surprise was the prescription list. Of course my first concern was the cost of insulin. My endocrinologist (diabetes doctor) had started me on an injection pen, and I was ready to go back to vials if the pens cost too much. What did I find? Every type of insulin cost exactly the same co-pay. I had expected older medications to be on a lower tier, making them cost less, but this was not the case. There was no insulin listed in tier one medicines, which are the generics. No insulin on tier two either. All of the injectable products such as insulin were in tier three, making them more expensive. The first question on my mind was “Why?” A medication as old as insulin, which has been available since 1921, ought to have at least one generic brand. But there is not. That is sad when you know the history of insulin. Doctors had known about diabetes for thousands of years but had no effective treatment for it. In the 1860s, a doctor named Paul Langerhans found little areas like islands in the pancreas where hormones were made. He named them after himself, the islets of Langerhans. Then in the 1880s, the researchers Oskar Minkowski and Joseph von Mering found that dogs whose pancreases were removed developed all the signs of diabetes. In 1910, another doctor named Sir Edward Sharpey-Schafer discovered which substance was missing from the pancreases of people with diabetes. Since this hormone came from the islets of Langerhans, he named it “insulin,” which comes from the Latin word for island. In 1921, two doctors named Frederick Banting and Charles Best determined how to e Continue reading >>
Identification And Comparison Of Insulin Pharmacokinetics Injected With A New 4‐mm Needle Vs 6‐ And 8‐mm Needles Accounting For Endogenous Insulin And C‐peptide Secretion Kinetics In Non‐diabetic Adult Males
Go to: Introduction The goal of injections of insulin is to reliably deliver insulin into the subcutaneous space without leakage or discomfort1. Recent developments in insulin pen technology have overcome many of the perceived barriers associated with insulin injection. However, discomfort associated with needle insertion still has an adverse effect on quality of life. The discomfort often associated with needle insertion is at least partly related to the diameter (gauge) and length of the needle, the wall thickness and the shape of the needle tip. Because of this, needle manufacturers have endeavored to overcome these limitations through redesigning and refining needle properties. Such improvements have had substantial benefits on quality of life and patients often prefer the newer needles2. However, needle length is subject to some limitations, as it governs the depth of injection and must be long enough to reach the subcutaneous tissue, without penetrating the underlying muscle. Many of the currently available needles are 5, 6 or 8 mm long. In Japan, 5‐ or 6‐mm needles are more frequently used than 8‐mm needles. Some patients use longer needles (mainly 8 mm) for no specific reason other than their long‐held habit or their physicians' preference. Although subcutaneous tissue thickness varies between injection sites, it is possible that 8‐mm needles inserted perpendicular to the skin could be inserted into muscle tissue8. Intramuscular injection is associated with increased pain relative to subcutaneous injection and can increase the rate of uptake of insulin, because of differences in tissue vascularity9. The use of shorter needles might overcome these problems. Shorter needles have reduced the likelihood of insertion into muscle and are often better tolerat Continue reading >>
- Identification of novel biomarkers to monitor β-cell function and enable early detection of type 2 diabetes risk
- World Diabetes Day 2017: Game-changing new app can measure glucose levels without a needle
- Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes
Cheapest Insulin Pen In India
Insulin pen is used for injecting insulin in the body of diabetic for treating it. Most of the diabetic care products such as insulin & pen are imported from foreign countries. And since they are highly priced, common man is out of reach. However you can buy cheapest insulin pen in India manufactured by the top pharmaceutical company – Sanofi Aventis under the brand name B D Micro Fine and Insuman 25/75 Optiset. Here are the details of low cost Insulin pen: 1 Insulin (Human)-80 iu/40iu/100iu Pen can be purchased at Rs. 46 Pen Insuman 25/75 Optiset (100 iu) 5 pen costs Rs. 241.33 (Note: Local taxes are not included) Quality wise generic medicines are similar to branded drugs sold by big pharmaceutical companies and do not pose any health risks provided they are prescribed by the doctors. How to Buy Diabetics can buy cheap insulin pen at healthkartplus with following buying options available: 1) Buy directly online at healthkartplus.com OR 2) E-mail [email protected] along with all the product details. And you will get all the products delivered at your doorstep. Make sure to include your correct mailing address, contact number and PIN code. You can then pay by cash upon receiving the product. Products are delivered within 1-2 days (24*7) Save Money on Diabetes Treatment Apart from buying cheap insulin pen, diabetics can save money on their healthcare costs: Purchasing medicines in bulk as you’ll get discount Buy online as medicines are sold at cheaper rates Many sites also run offers for returning customers. Even if they don’t then you should ask them to provide discounts for all the purchase made Compare prices online at various websites and then buy Always ask your doctor for generic substitute for the prescribed drug Continue reading >>
Prior Authorization Approval Criteria
Page 1 of 1 11/16/04 Rev 07/2005 Rev 3/12/08 Insulin Pen Generic Name: Insulin Pen Brand Name: Novolog Penfill, Novolog Flexpen , Apidra Solostar, Levemir Flexpen, Novolog Mix 70/30 Flexpen Medication Class: insulin administration system FDA Approved Uses: Patients with Type I or II insulin-dependent diabetes Duration of Therapy: indefinite Approximate cost (based on AWP 2008): varies depending on the insulin Criteria for Use: (bullet points below are all inclusive unless otherwise noted) • The indicated diagnosis (including any applicable labs and /or tests) and medication usage must be supported by documentation from the patient’s medical records. • Patient must have clinically diagnosed Type I or Type II diabetes • Patient must be able to monitor blood glucose • Patient must have 1 or more of the following: o Unable to draw up insulin into a syringe or self administer, due to mechanical, physical or environmental factors o Visual impairment o Requires 1 or more injections per day during a work/school period o Has severe phobia to traditional syringes and needles as documented in the patient’s medical records Or • Patient is a child under 18 years of age. Not Approved if: • Does not meet the above criteria • Has any contraindication to the corresponding insulin P&T Approval: ___________________________________________ Date: ______________________ Continue reading >>
Novolog® (insulin Aspart Injection) 100 U/ml Indications And Usage
NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. NovoLog® (insulin aspart injection) 100 U/mL is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients. Never Share a NovoLog® FlexPen, NovoLog® FlexTouch®, PenFill® Cartridge, or PenFill® Cartridge Device Between Patients, even if the needle is changed. Patients using NovoLog® vials must never share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia. These changes should be made cautiously under close medical supervision and the frequency of blood glucose monitoring should be increased. Hypoglycemia is the most common adverse effect of insulin therapy. The timing of hypoglycemia may reflect the time-action profile of the insulin formulation. Glucose monitoring is re Continue reading >>
Insulin
What are Insulin Insulin is a hormone that occurs naturally in the body and can also be given by injection as a treatment for diabetes. Naturally-occurring insulin is made by the beta cells of the Islets of Langerhans located in the pancreas. It helps the cells of the body to uptake glucose (sugar) found in the carbohydrates we eat so that it can be used as energy or stored for later use. Insulin also controls glucose release from the liver. One of the main roles of insulin is to keep blood glucose levels from going too high (hyperglycemia) or too low (hypoglycemia). People with type 1 diabetes do not make enough insulin to satisfy their body's needs or make none at all. Insulin given by injection acts similarly to naturally occurring insulin. There are more than 20 different types of insulin available for diabetes treatment in the United States. The various types of insulin differ in several ways: such as source (animal, human or genetically engineered), the time for insulin to take effect and the length of time the insulin remains working (ie, rapid acting, short acting, intermediate acting, long acting or very long acting). Insulin is used to treat Type 1 diabetes and it may be used together with oral medications in the later stages of Type 2 diabetes. List of Insulin: Filter by: -- all conditions -- Drug Name View by: Brand | Generic Reviews Avg. Ratings Humulin R (Pro, More...) generic name: insulin regular 0 reviews 10 NovoLog Mix 70 / 30 FlexPen (More...) generic name: insulin aspart/insulin aspart protamine 0 reviews 10 Humalog Mix 75 / 25 (More...) generic name: insulin lispro/insulin lispro protamine 2 reviews 9.5 NovoLog Mix 70 / 30 (More...) generic name: insulin aspart/insulin aspart protamine 3 reviews 9.5 ReliOn / Novolin 70 / 30 (More...) generic name: i Continue reading >>
Insulin Prices Have Skyrocketed, Putting Drug Makers On The Defensive
Here’s a sticking point for diabetics: the cost of insulin more than tripled — from $231 to $736 a year per patient — between 2002 and 2013, according to a new analysis. The increase reflected rising prices for a milliliter of insulin, which climbed 197 percent from $4.34 per to $12.92 during the same period. Meanwhile, the amount of money spent by each patient on other diabetes medications fell 16 percent, to $502 from $600, according to a research letter published Tuesday in the Journal of the American Medical Association. “Insulin is a life-saving medication,” said Dr. William Herman, a coauthor of the analysis and a professor of medicine and epidemiology at the University of Michigan School of Public Health. “There are people with type 1 diabetes who will die without insulin. And while there have been incremental benefits in insulin products, prices have been rising. So there are people who can’t afford them. It’s a real problem.” The analysis also found that the cost of various widely used oral diabetes drugs either dropped in price or did not rise nearly as significantly as insulin. Metformin, for instance, which is available as a generic, fell to 31 cents in 2013 from $1.24 per tablet in 2002. And the newer class of diabetes drugs known as DPP-4 inhibitors rose 34 percent since becoming available in 2006. The researchers analyzed data from nearly 28,000 diabetes patients found in the Medical Expenditure Panel, a database on health care costs maintained by the US Department of Health and Human Services. About 1 in 4 people used insulin and two-thirds took a pill. Toward the end of the study period, a small percentage began taking new injectable medicines that are designed to complement pills. There have been previous efforts to track insulin pric Continue reading >>
'generic' Biosimilar Insulin Becoming Reality!
As our community struggles with the skyrocketing prices of insulin, new hope dawns. After screaming for years that "WE WANT GENERIC INSULIN!," we are now finally entering the long-awaited era of biosimilars (even if they aren't technically called that by U.S. regulatory leaders), that are basically similar lower-cost versions of already-approved insulins. To be clear, this is a whole new world of insulin products different from anything we've seen before. We’re not talking about those Walmart "generic" insulins that are just cheap forms of older-gen products like R, N, and 70/30 mix simply sold under Walmart’s ReliOn brand name. In contrast, these new biosimilar “generics” are actually novel formulations that copy the biological molecule of an existing insulin. As of today, Dec. 15, Eli Lilly's new Basaglar basal insulin becomes available to buy here in the U.S. This is the first so-called “follow-on” version of competitor Sanofi's successful long-acting insulin Lantus, and there’s been a ton of buzz about its potential to bring down insulin prices across the board and reshape insurance coverage. This is the first, and we expect to see a second biosim launched within a year, followed by a variety of these lower-cost insulins, both fast-acting and long-acting. You may be surprised to see that these copycat insulins are not coming from newcomers, but from established Pharma companies themselves, now that they finally have the opportunity to undercut each other as their signature insulins go off patent. But that's what it is, Folks: Insulin Wars. And although we may be caught in the middle as patients, we do have a chance to save money with the introduction of these new generics we've been demanding for so long. 'Generic' Insulins Coming Soon The three bigges Continue reading >>
How To Get Insulin At A Cheaper Price
Insulin can be expensive. If you’re one of the 6 million Americans with diabetes relying on this main-stay treatment, you could be paying out-of-pocket costs anywhere from $120 to $400 per month, according to a 2015 New England Journal of Medicine commentary. Drugs such as Lantus (insulin glargine) and Levemir (insulin detemir) have seen significant cost increases, according to a recent trend report by pharmacy benefit manager Express Scripts. One reason for the high prices is the lack of generic options for insulin. So for now, you’re stuck having to search around to find affordable options. Where do you shop for more affordable insulin? For some people though, high drug costs can mean making difficult financial choices. Our national polls show people might cut back on groceries and paying bills to pay for their medications. To minimize your costs, consider these options: Prescription Assistance Programs If you don’t have health insurance or are without drug coverage, look into applying for a patient assistance program (PAP). Through the nonprofit NeedyMeds, you can find some programs that offer free or low-cost insulin as long as you meet the eligibility requirements. Those are usually based on your insurance status, income, and diagnosis. You might also qualify for a diagnosis-specific program that can help you save on syringes, pumps, and other diabetes supplies. Pharmacists are also a great resource and can help you find a PAP that meets your financial needs. Switch Drugs Another way to save is by asking your doctor whether there’s a lower-priced insulin that’s right for you. While “long-acting” is a more popular type of insulin, it's also more expensive, but that doesn’t necessarily mean it works better. “It’s mostly a marketing ploy,” says M Continue reading >>
How Do I Get Lantus Insulin Less Expensively?
November 2, 2013-- How do I get Lantus Insulin Less Expensively? DCIN receives this question a few times a week from US caregivers of diabetic cats. I am often amazed by the question because of the “good” insulins for diabetic cats, Lantus can be the least expensive per unit. The problem often lies in knowing how to find the insulin inexpensively. (The hints I give also apply to Levemir, another human insulin often used by diabetic cats.) Your vet gave you a prescription that probably read “U100 Glargine/Lantus 10ml vial.” Lantus is the brand name for the generic insulin Glargine. Lantus is an insulin for humans and is only available from a human pharmacy (although some vets do hold some in stock). The company Sanofi makes Lantus, and no other companies currently make a generic Glargine because Sanofi still has an international patent on the insulin. That may change in 2014, and by then Sanofi may have developed a “second-generation” Lantus that is patent protected. Lantus is a U100 insulin, which describes the concentration of the insulin in the liquid suspension. A 10ml vial is the insulin’s containment device. It is a small glass bottle with a rubber stopper at the end that you pierce with a syringe. At a US retail pharmacy, a 10ml vial of Lantus can cost about $180 to $200. WOWZA! That does seem cause for sticker shock. A 10ml vial of U100 insulin holds 1000 units of insulin. At $200/vial, that is a price of $.20/unit. If your cat gets 2 units of insulin twice a day, that is $.80/day for its insulin (if you could completely use a vial of Lantus insulin). It would cost less each day to give your cat its life-saving medicine that to buy a soda from a vending machine. However, the problem with buying Lantus in a 10ml vial is that, properly handled, Lantus Continue reading >>
Fda Approves New Insulin Glargine Basaglar – The First “biosimilar” Insulin In The Us
Twitter Summary: 1st ever “biosimilar” insulin approved in US – potential to come cheaper than other insulins, with launch in December 2016 Lilly/BI recently announced the FDA approval of its long-awaited biosimilar insulin glargine, Basaglar, for type 1 and type 2 diabetes. Basaglar is biologically similar to Sanofi’s basal insulin Lantus (insulin glargine), including the same protein sequence and a similar glucose-lowering effect. While the FDA does not call it a “biosimilar” drug for regulatory reasons, it can essentially be thought of as an alternative form of Lantus. Pricing for Basaglar is unknown at this time (more on this below), and the drug will not be launching in the US until after December 15, 2016. Why are “biosimilar” insulin options exciting? Most notably, they could potentially be offered at lower costs than brand name insulins. Basaglar has already launched in several international countries (under the brand name Abasaglar) and is typically priced at a 15%-20% discount relative to Lantus in those markets. It’s not clear yet how the discounts for Basaglar will compare in the US, and how much less patients with insurance might pay. “Generic” versions of drugs in the US typically come at a 50-80% discount to the original product. But unlike most generic drugs, biosimilar insulins are much more expensive to manufacture, so it’s unlikely they’ll see that same level of discount in the US. Indeed, Novartis launched the first “biosimilar” drug approved in the US last September (not in diabetes), which came at a 15% discount. Still, we’ve heard great optimism that biosimilar insulin glargine will help patients facing higher insulin costs. At the IDF conference in December, Dr. Matthew Riddle suggested that of all the insulins new Continue reading >>
When You Can't Afford The Insulin That You Need To Survive | How To Use The Cheap "old-school" Insulin
Note: BootCamp for Betics is not a medical center. Anything you read on this site should not be considered medical advice, and is for educational purposes only. Always consult with a physician or a diabetes nurse educator before starting or changing insulin doses. Did you know that all type 1 diabetics and some type 2 diabetics need injectable insulin in order to live? Put another way, if a diabetic needs insulin in order to live, and the diabetic does not get insulin, the diabetic will die. Diabetic death from Diabetic Ketoacidosis is a grisly process, during which acid starts running through your bloodstream, searing your vessels and organs while your body shrivels up in dehydration as it tries to push the acid out of your body through your urine and lungs, and, left untreated, the condition shuts down your organs one by one until you are dead. If you're lucky, your brain will be the first thing to swell itself into a coma and you'll be unconscious for the remainder of the organ failures. In some cases, this grisly diabetic death can take a few days or weeks to complete its process. Or, if you're one of the luckier less-resistant insulin-dependent type 2 diabetics, you may actually get away with staying alive for quite a few years and suffer only some heart disease, stroke, kidney damage/failure, neuropathy, limb amputations and blindness. (my intent in describing how lack of insulin leads to death is not to cause fear in people with diabetes or their loved ones; rather, my intent is to make clear the reality that injectable insulin is absolutely vital to diabetics who depend on injectable insulin to live) While I'd love to go off on a political rant about how insulin should be a basic human right for all insulin-dependent diabetics (and why the hell isn't it?), that' Continue reading >>
