diabetestalk.net

Fastest Acting Insulin

Share on facebook

New Ultra-rapid-acting Insulin Formulation

BIOD-531 is a new ultra-rapid-acting insulin formulation that has been shown to work better than current therapies at treating diabetes in a mid-stage trial…. BIOD-531 is an ultra-rapid-acting formulation of recombinant human insulin (RHI) at a concentration of 400 units/ml (U-400) combined with EDTA, citrate and magnesium sulfate. In the Phase 1 Study 3-150, the results of which were released in February 2014, BIOD-531 administered to non-diabetic, obese volunteers demonstrated ultra-rapid absorption and onset of action in comparison with Humalog Mix 75/25 and Humulin R U-500, and had an extended duration of action that is expected to be suitable for basal insulin needs. The recently completed Study 3-152 was designed to test the hypothesis that a single dose of BIOD-531 would confer better postprandial glucose control for two consecutive meals compared to Humalog Mix 75/25 when administered to type 2 diabetes patients with moderate insulin resistance. In Study 3-152, glucose profiles were assessed after single subcutaneous injection of 0.6 U/kg doses of the study drugs administered with a standardized breakfast on separate days in a randomized four arm cross-over sequence in wh Continue reading >>

Share on facebook

Popular Questions

  1. Autumn

    Two days ago I purchased 2 vials of insulin. I usually buy 2 at a time.
    Insulin I purchased had expiration of 2/10.
    I read on line about the expiration dates on insulin. I read the strength will become less after time, even if it has not open. Is this correct? Usually vials are a year or more from expiration when I get them. One replaced today does not expire till 2012. They would not replace one that had the box open, even though seal was not broken. Is this insulin still as effective as it should be? Should I just consider a loss and go right to the 2012 vial?
    Thanks!

  2. k9diabetes

    I know people who have used insulin past the expiration date, primarily because the insulin they were using had been discontinued and they couldn't buy any more of it. Since their dogs didn't do well on any of the other insulins available, they stockpiled it and extended its use past the expiration for quite a while.
    It's not like the insulin will magically cease to work when it hits that date. They just say that it will be good at least that long.
    Rather than going straight to the 2012 bottle, I would use the one that's nearing its expiration date first as you are currently still using it within it's expiration date.
    And then if you see that it's a problem, you could switch to the 2012 bottle. Chances are good the bottle you have that's about to expire will work just fine.
    Natalie

  3. eileen

    I completely agree with you Natalie. Regulations say that there must be an expiry date on the insulin so that it can be guarateed until this date. There is no way it will, as you put it, " magically cease to work..."
    I would imagine if the unopened vial had been stored properly in the fridge it will still be good long after the printed date.
    Eileen/Mil

  4. -> Continue reading
read more close

Related Articles

  • Long Acting And Short Acting Insulin

    What’s the difference between the different types of insulin? Long-acting, short-acting, premixed, learn more about all three. You may have a lot of questions as you begin insulin therapy. What are the different types of insulin available? Which should I be using and when? Insulins differ based on 3 key factors: 1 how quickly they work when they peak how long they last (duration) This table compares these factors in the types of insulin availab ...

    insulin Jan 20, 2018
  • Fastest Acting Insulin

    Fasting acting insulin is the insulin you inject to cover the rise in your blood sugar that occurs after you eat a meal. They are called "fast acting" because unlike the basal insulins, Lantus and Levemir, they are absorbed relatively quickly after injection. This is what makes it possible to use these fast acting insulins to cover a meal. In theory, if you can figure out how many grams of carbohydrate one unit of fast acting insulin will cover, ...

    insulin Jan 26, 2018
  • List The Steps For Mixing A Short Acting And Long Acting Insulin In The Same Syringe

    Intradermal injections (ID) are injections administered into the dermis, just below the epidermis. The ID injection route has the longest absorption time of all parenteral routes. These types of injections are used for sensitivity tests, such as TB (see Figure 7.13), allergy, and local anesthesia tests. The advantage of these tests is that the body reaction is easy to visualize, and the degree of reaction can be assessed. The most common sites us ...

    insulin Sep 22, 2018
  • What Is The Fastest Acting Insulin

    (Reuters) - The U.S. Food and Drug Administration on Friday approved Novo Nordisk’s fast-acting insulin to treat diabetes. The product, known as Fiasp, is designed to help diabetics control post-meal spikes in blood sugar. It is already approved in Canada and Europe. Fiasp, or faster acting insulin asparte, is designed to work faster than existing fast-acting insulin such as Eli Lilly and Co’s Humalog and Novo Nordisk’s own NovoLog, known a ...

    insulin Apr 28, 2018
  • Why Do You Draw Up Short Acting Insulin Before Long Acting?

    Why do I need to take insulin? When you digest food, your body changes most of the food you eat into glucose (a form of sugar). Insulin allows this glucose to enter all the cells of your body and be used as energy. When you have diabetes, your body doesn’t make enough insulin or can’t use it properly, so the glucose builds up in your blood instead of moving into the cells. Too much glucose in the blood can lead to serious health problems. All ...

    insulin Sep 22, 2018
  • Which Is The Fastest Acting Insulin?

    Novo Nordisk has announced that their ultra-fast rapid-acting insulin aspart called Fiasp has been approved by the European Commission, covering all 28 European Union member states. According to a GlobeNewswire press release, Fiasp is a new-generation mealtime insulin that works faster and more like the natural physiological insulin response to meals. It has a similar safety profile to Novolog insulin in the US and NovoRapid in the UK and is appr ...

    insulin Apr 1, 2018

Popular Articles

More in insulin