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Fastest Acting Insulin

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Full story: http://bit.ly/1zrXJ4F Cone snails spray an incapacitating chemical cocktail to knock out fish. And understanding the structure of a fast-working insulin molecule in that cocktail may help inform drug development for diabetes

Slow-moving Snails Make Fast-acting Insulin

Cone snail venom could inspire new drugs for treatment of diabetes. Insulin — a life-saving drug for diabetics — is also the deadly weapon of choice for aquatic cone snails, which release a specialized version of insulin to rapidly stun their fish prey before eating them alive. The cone snail insulin works so quickly that it could improve upon current fast-acting therapeutic insulin, potentially leading to new drugs for treating diabetes, according to a new paper in Nature Structural & Molecular Biology. “You look at what venoms animals make to affect the physiology of their prey, and you use that as a starting point," says study co-author Helena Safavi of the University of Utah in a press release. "You can get new ideas from venoms. To have something that has already been evolved -- that's a huge advantage." Human insulin gets secreted from the pancreas, stimulating the body’s cells to take up glucose from the bloodstream. When insulin production is impaired, blood glucose becomes elevated, resulting in diabetes. Synthetic insulin injections are commonly used as treatment. When insulin is stored in the pancreas, groups of six molecules will stick together. Even injected in Continue reading >>

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Popular Questions

  1. WelshWarrior

    How long to seperate carbs and hgh

    Off slin for 4 weeks. How long should I wait before ingesting carbs after my hgh shot?
    I have searched for ages and couldn't find this info but know there were some threads that included it.....

  2. Gear

    Since HGH takes approx 30 - 40min to travel to the liver post injection, I would wait about an hour before consuming carbohydrates. Keep in mind that you can still have carbs around HGH injection but not too much as it may severly effect your blood glucose.
    -Gear

  3. WelshWarrior

    Thanks Gear. So if I need a shot mid pm, about 1hr 30 before and after carbs is okay? (ie halfway between a 3 hour meal window.)

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http://diaberex.com/ Long Acting Insulin - What Is Long Acting Insulin? Type 2 diabetes is a chronic health condition that is characterized by a disruption in the normal way that sugars are processed by the body. Over time the pancreas decreases its output of sugar storing insulin, resulting in high blood sugar levels that cause damage throughout the body. Often patients are asked to modify their diet and to exercise to help reduce sugars. When this alone does not work, oral medications can be started to help regulate sugars. As the amount of insulin produced by the pancreas continues to decrease it is often necessary to start insulin. Long acting insulin is injected once per day and is used to reduce fasting glucose levels to a more normal range. These medications cause a reduction in the sugar levels outside of meal time and mimics the normal function of the pancreas in regulating fasting sugar levels. Long acting insulin can be used alone, in combination with other insulins or with oral medications for type 2 diabetics. This type of insulin is beneficial because it is injected daily and does not create highs and lows in glucose readings.

Faster Acting Insulin Could Be On The Horizion

When I first saw the article my first thought was faster lows…it kind of scared me. But after reading it, there seems to be some great promise in an insulin you can take before or even after you have eaten and it covers the meal quickly but also ends quicker, reducing the risk of a hypo event after taking it. Other countries have already approved it and it is looking like the concerns the FDA had are being addressed. Should be interesting to see. Here is the full article: Good morning. I am new here and looking for sound advice. My husband has type two diebetes and we can't seem to get his blood sugar down and we don't want more medication....We want to be medication free. I am following the Ketos diet because I need to lose weight but hubby is very thin and... I am my husband's caregiver and he has Type 2 Diabetes. I found this group and have already got a lot of questions answered so thanks! We have been hearing so much about Metformin and after him losing 50+ lbs. are wondering if he even needs to be on it to start with. His numbers have only been... Hello everyone, I was diagnosed with diabetes today. My A1C is at 10. I’m so lost and confused. I spent the entire day crying. Continue reading >>

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Popular Questions

  1. ldydi53

    how soon should you eat after taking a dose of Lantus Solostar?

    how soon should you eat after taking a dose of Lantus Solostar?

  2. SU suzanne66

    Lantus Solostar (Insulin glargine) is a man-made form of a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting form of insulin .
    You may eat as soon as you like after using the insulin. Remember to test your blood- glucose regularly.
    See https://www.drugs.com/mtm/lantus-solostar-pen.html

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how to draw out long acting and short acting insulin

Short-acting Insulins

Rapid-Acting Analogues Short-Acting Insulins Intermediate-Acting Insulins Long-Acting Insulins Combination Insulins Onset: 30 minutes Peak: 2.5 - 5 hours Duration: 4 - 12 hours Solution: Clear Comments: Best if administered 30 minutes before a meal. Mixing NPH: If Regular insulin is mixed with NPH human insulin, the Regular insulin should be drawn into the syringe first. Aspart - Novolog ®: Compatible - but NO support clinically for such a mixture. Draw up Novolog first before drawing up Regular Insulin. Lispro - Humalog ®: Compatible - but NO support clinically for such a mixture. Draw up Humalog first before drawing up Regular Insulin. Mixtures should not be administered intravenously. When mixing insulin in a syringe, draw up the quickest acting insulin first (e.g. draw up Humalog or Novolog before drawing up Regular Insulin, or draw up Regular insulin before Novolin N (NPH) or Lente insulin. CLINICAL PHARMACOLOGY Insulin is a polypeptide hormone that controls the storage and metabolism of carbohydrates, proteins, and fats. This activity occurs primarily in the liver, in muscle, and in adipose tissues after binding of the insulin molecules to receptor sites on cellular plasma Continue reading >>

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Popular Questions

  1. Limberis

    porcine (pork) insulin hyperin

    My father-in-law is 85 years old and has lived with diabetes since he was a teenager. Obviously, he manages his diabetes well. I need help finding him pork insulin at a better price than through the UK with $200 shipping; although $50 per 10ml vial can't be beat. Anybody use it and have a good source? Thanks

  2. Krisb0701

    Hello and welcome. Unfortunally here in the states not many people if any at all use the animal insulins. The majority use human insulin. I do not know where to look for it. My aunt who lives in germany says they use the animal insuins over there. You could try looking in some of the other europe countries. Kris

  3. blondy2061h

    Has he ever tried human insulin? It would be much easier to find.

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