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Do Lantus Pens Need To Be Refrigerated?

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Unrefrigerated Lantus Question

Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. Went to the drug store, picked up new boxes of Lantus Solostar and Humalog Pens. Went home, got distracted, forgot to put pens in fridge for almost two hours. They were at room temperature, no sunlight or other warmth exposure. Did some research on the net and also called the manufacturers. Bottom line is this: Humalog should be okay with only very minimal efficacy difference (<1% difference), so I'm okay there. Sanofi Aventis tells me that the Lantus pens will only be good for 28 days, even though they were not opened. This translates to my having to throw out 2 of the 5 Solostar pens. Question- anyone have any experience with using unrefrigerated Lantus longer than 28 days? I always kept my Lantus at room temperature. I used it beyond the 28 days without a problem. I've had Lantus vials, being used, out at room temp for up to 60 days with no measurable signs of lost potency for me. Room temp in the summer time can be in the upper 70s for short periods. I don't see having left the pens out at room temp Continue reading >>

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Popular Questions

  1. Essie

    Does anyone use the Frio wallets? Do you recommend them.
    I started using insulin in November and have yet to encounter hot weather, but it is coming very soon. Where I live high 90's and triple digits are common. I am mostly homebound but we are planning some long day trips coming up. I am looking at two things. One, keeping my current opened Humalog and Lantus vials cool and it seems like the Frio will do this. Secondly because I worry that something could bappen while we are several hours away from home that would delay our return, I would like to carry an un-opened vial of each in case. If not opened but kept at room temperature will it now have the "good for 28 days" clock start ticking? Is there a better way to carry those?
    I would love to hear what others do to keep their insulin cool on the go.
    ​Thank you!

  2. mollythed

    I wouldn't worry about keeping a single pen of each type in a Frio pack for a day. The only significant factor I would be concerned about is that because the pack cools by evaporation, it is important to keep it in a place where air can circulate freely, not tucked away snugly in a purse or backpack, and not in directed sunlight all the time.
    I am a little less confident about how to carry a second pen. Usually, if you are traveling by car or plane, and carrying insulin you want to use for several days away from home, you can use a lunchbox, with ice or a reusuable icepack to keep the box cool, but wrapping the insulin pen or vial in something like a washcloth or towel to protect it from getting TOO cold and freezing. You can replace the ice as needed while you are traveling, with ice from flight attendants, a hotel, or even when eating at a restaurant.
    It gets a little more "iffy" keeping insulin in a Frio type pack. One thing to consider is how long it takes you to use each pen. If you are quite insulin resistant and normally use up an entire pen in, say, three days, and you really do use your spare pen next, so that it is reasonably cool for two to six days, you are probably fine with the Frio. If you normally use only ten units a day, so that the spare pen might go unrefrigerated for nearly a month, I would suggest using the lunch box method instead for your spare pens.
    The problem with insulin when it doesn't stay cool is that it gradually loses its effectiveness. It can still be used, but you may need a little more of it to get the effect you need. If I brought a pen home from a trip unused, I would want to be VERY careful to make sure I did begin using it regularly as soon as I needed a new pen. and watch for any loss of strenght as the days went by. I wouldn't just keep it separate to be used once again as a spare.
    When I bring new insulin home from the pharmacy, the expiration date is usually about two years in the future. Under the right conditions, it does last a long time. There are no guidlines, no clear-cut rules once we start to take liberties with those rules, and nobody wants to make any promises for those inbetween conditions. What we do know, is the longer it stays warm, and the warmer it gets, the sooner it will start to lose its strength. That's where we need to use a little common sense.

  3. Essie

    Thank you Molly. I don't know if it makes a difference but I don't have pens. I have the old fashioned syringes/vials of jnsulin.

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Refrigerating Lantus Pens?

This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More. I've always refrigerated normal Lantus vials because I was told it has to stay in the fridge.. no problem keeping it in the fridge as I don't need to be carrying it around with me anyway. Since we just switched to the pens though, it says on the back not to keep it in the fridge (unless unused of course). Does it matter if it's refrigerated or not? I would assume if the vial needed to be refrigerated, so would the pen.. maybe it doesn't need to be refrigerated at all? Once I took one out to open it, I kept it out of the fridge - tossed at 28 days same as Humalog. We were told an open vial or pen could stay out of the fridge for 28 days. Sophie and my dad(who is a t2d)both say cold lantus stings We did/do the same thing as previous posters. Kept in the fridge, but once opened, kept out of the fridge until time to toss it. All clear insulins are ok unrefrigerated for a month. You are supposed to store it in the fridge before opening so that you don't eat into that month when you don't need to. (Anecdotally, I've stored insulin unrefrigerated for many months without a problem, Continue reading >>

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Popular Questions

  1. Essie

    Does anyone use the Frio wallets? Do you recommend them.
    I started using insulin in November and have yet to encounter hot weather, but it is coming very soon. Where I live high 90's and triple digits are common. I am mostly homebound but we are planning some long day trips coming up. I am looking at two things. One, keeping my current opened Humalog and Lantus vials cool and it seems like the Frio will do this. Secondly because I worry that something could bappen while we are several hours away from home that would delay our return, I would like to carry an un-opened vial of each in case. If not opened but kept at room temperature will it now have the "good for 28 days" clock start ticking? Is there a better way to carry those?
    I would love to hear what others do to keep their insulin cool on the go.
    ​Thank you!

  2. mollythed

    I wouldn't worry about keeping a single pen of each type in a Frio pack for a day. The only significant factor I would be concerned about is that because the pack cools by evaporation, it is important to keep it in a place where air can circulate freely, not tucked away snugly in a purse or backpack, and not in directed sunlight all the time.
    I am a little less confident about how to carry a second pen. Usually, if you are traveling by car or plane, and carrying insulin you want to use for several days away from home, you can use a lunchbox, with ice or a reusuable icepack to keep the box cool, but wrapping the insulin pen or vial in something like a washcloth or towel to protect it from getting TOO cold and freezing. You can replace the ice as needed while you are traveling, with ice from flight attendants, a hotel, or even when eating at a restaurant.
    It gets a little more "iffy" keeping insulin in a Frio type pack. One thing to consider is how long it takes you to use each pen. If you are quite insulin resistant and normally use up an entire pen in, say, three days, and you really do use your spare pen next, so that it is reasonably cool for two to six days, you are probably fine with the Frio. If you normally use only ten units a day, so that the spare pen might go unrefrigerated for nearly a month, I would suggest using the lunch box method instead for your spare pens.
    The problem with insulin when it doesn't stay cool is that it gradually loses its effectiveness. It can still be used, but you may need a little more of it to get the effect you need. If I brought a pen home from a trip unused, I would want to be VERY careful to make sure I did begin using it regularly as soon as I needed a new pen. and watch for any loss of strenght as the days went by. I wouldn't just keep it separate to be used once again as a spare.
    When I bring new insulin home from the pharmacy, the expiration date is usually about two years in the future. Under the right conditions, it does last a long time. There are no guidlines, no clear-cut rules once we start to take liberties with those rules, and nobody wants to make any promises for those inbetween conditions. What we do know, is the longer it stays warm, and the warmer it gets, the sooner it will start to lose its strength. That's where we need to use a little common sense.

  3. Essie

    Thank you Molly. I don't know if it makes a difference but I don't have pens. I have the old fashioned syringes/vials of jnsulin.

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Find Resources To Help You With Toujeo (insulin Glargine Injection) 300 Units/ml --including Samples, Videos, Published Clinical Studies, And Faq's.

This site is intended for U.S. Healthcare Professionals only. PLEASE NOTE: This reprint includes information that is not contained within the full prescribing information (PI) for Toujeo (insulin glargine injection) 300 Units/mL and is not intended to offer recommendations about Toujeo that are inconsistent with the PI. Please read the full indication, the Important Safety Information and the full Prescribing Information . Sanofi US does not review the information contained in this website and/or database for content, accuracy, or completeness. Use of and access to this information is subject to the terms, limitations, and conditions set by the website and/or database producer. Sanofi US makes no representation as to the accuracy or any other aspect of the information contained on such website and/or database, nor does Sanofi US necessarily endorse such website and/or database. You are about to leave sanofi site for U.S. Sanofi US does not review the informationcontained on this website and/or databasefor content, accuracy or completeness. Useof and access to this information is subject tothe terms, limitations and conditions set by thewebsite and/or database producer. This site m Continue reading >>

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Popular Questions

  1. User34456

    Lantus Need refrigeration?

    I was told my Novelin does not need to be refrigerated but how about Lantus? Is it mandatory or just recommended? I am starting to travel and it would make a big difference if I could just throw them along with my kit in my purse and just go....

  2. fgummett

    Should say on the package insert but I understand that most insulins are stable at room temperature for at least 28 days (some longer). IIRC Lantus occasionally stings and the advice usually given is to ensure it is not refrigerated as this can make the stinging worse. I use Levemir and keep the spares in the fridge door but the current use penfill out

  3. User34456

    When I buy the Lantus it always comes directly out of the pharmacy fridge so I have always kept it in mine but you are right, it does sting. Is that the reason? I also keep my Novelin in the fridge just because it's convenient as that's where the Lantus is. Since I live in Florida it is 90 degrees in my house so I am afraid to leave them out.

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